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    • 3. 发明申请
    • PEST CONTROL COMPOSITIONS AND METHODS
    • 害虫控制组合物和方法
    • WO2009117621A1
    • 2009-09-24
    • PCT/US2009/037733
    • 2009-03-19
    • TYRATECH, INC.ENAN, Essam
    • ENAN, Essam
    • A61K31/535
    • A01N61/00A01N65/00A01N65/08A01N65/16A01N65/22Y02A50/331A01N31/16A01N37/18A01N37/40A01N37/46A01N41/08A01N43/08A01N43/16A01N43/90A01N47/02A01N47/46A01N51/00
    • Embodiments of the present invention provide compositions for controlling a target pest including a first agent and a second agent comprising a pest control product or a signal cascade modulator, wherein the first agent and the second agent act synergistically to control the target pest. The first agent can be capable of interacting with a receptor in the target pest. The pest control product can have a first activity against the target pest when applied without the active agent and the compositions can have a second activity against the target pest; and the second activity can be greater than the first activity. Embodiments of the invention can include compositions that modulate the signal cascade initiated by the binding of ligands to, for example, cell surface receptors. Methods of screening such compositions are also disclosed.
    • 本发明的实施方案提供了用于控制目标害虫的组合物,其包括第一药剂和包含害虫防治产品或信号级联调节剂的第二药剂,其中所述第一药剂和所述第二药剂协同作用以控制所述有害生物。 第一种药剂能够与目标害虫中的受体相互作用。 当没有活性剂时,害虫防治产品可以具有抵抗目标害虫的第一活性,并且组合物可以具有针对目标害虫的第二活性; 并且第二活动可以大于第一活动。 本发明的实施方案可以包括调节由配体结合例如细胞表面受体引发的信号级联的组合物。 还公开了筛选这些组合物的方法。