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1. 发明申请

WO2008077263A3 DENTAL IMPLANT AND METHOD FOR THE PRODUCTION THEREOF 审中-公开
标题翻译：假牙和方法及其
公开(公告)号：WO2008077263A3
公开(公告)日：2008-08-28
申请号：PCT/CH2007000638
申请日：2007-12-17
申请人： THOMMEN MEDICAL AG , SCHLOTTIG FALKO , ORTEGA CRUZ LUIS ALFONSO
发明人： SCHLOTTIG FALKO , ORTEGA CRUZ LUIS ALFONSO
IPC分类号： A61F2/30 , A61C5/73 , A61L27/02
CPC分类号： A61F2/30767 , A61C2008/0046 , A61F2002/30906 , A61F2002/3092 , A61F2002/30968 , A61F2310/00179 , A61L27/047 , A61L27/10 , A61L27/56 , B22F3/1109 , B22F2998/00 , B22F2998/10 , B22F2999/00 , Y10T29/49568 , B22F2207/11 , B22F3/04 , B22F3/225 , B22F2003/247 , B22F3/1007 , B22F2003/241
摘要： The invention discloses a novel implant provided with a macroporous surface on the top surface, and a method for the production of such a metallic and/or ceramic implant having a textured, particularly porous, surface for the at least partial insertion in hard tissue, such as in a bone, and/or into soft tissue. The implant is produced as a green compact, at least in sections, using a cold isostatic pressing, casting, and/or injecting (CIM, MIM) with subsequent sintering to obtain an implant, and is particularly characterized in that the surface is modified and/or prepared before sintering such that a macroporous surface is present after sintering without requiring any finishing.
摘要翻译：公开的是一种新的，具有大孔表面的植入物和用于制造这样的金属和/或具有陶瓷植入物的纹理化，特别是多孔表面上至少部分地插入到硬组织，例如在骨和/或软组织的方法所提供的表面上。所述植入物，从而产生至少部分地用冷等静压的辅助下，模制和/或喷涂（CIM MIM）为生坯随后烧结到植入物，并且特别是其特征在于，前表面烧结改变，和/或制备是，如果没有附加的后处理大孔表面在烧结后存在。

2. 发明申请

WO2009106502A3 IMPLANT AND METHOD FOR THE MANUFACTURE THEREOF 审中-公开
标题翻译：植入物和方法及其
公开(公告)号：WO2009106502A3
公开(公告)日：2010-07-01
申请号：PCT/EP2009052112
申请日：2009-02-23
申请人： THOMMEN MEDICAL AG , SCHNABELRAUCH MATTHIAS , KAUTZ ARMIN REX , SCHLOTTIG FALKO
发明人： SCHNABELRAUCH MATTHIAS , KAUTZ ARMIN REX , SCHLOTTIG FALKO
IPC分类号： A61L27/34 , A61K31/366 , A61K47/48
CPC分类号： A61L27/34 , A61K31/366 , A61K47/61
摘要： What is described is an implant that comprises a coating, at least in areas, in the implanted state in the surface areas that are at least directly in contact with skin and/or soft tissue. The implant is preferably characterized in that the coating comprises both a statin, such as simvastatin, in the hydrolyzed or unhydrolyzed form, or pharmaceutically compatible salts thereof, as well as at least one other component selected from the group consisting of branched or linear, substituted or unsubstituted, saturated or partially unsaturated C10-C30 alkyl, alkenyl, alkylaryl, aryl, cycloalkyl, alkylcycloalkyl, alkylcycloaryl amines or mixtures thereof and/or at least one water-soluble ionic polymer component. A method for production such an implant is also described as well as a composition that can be used in such a method.
摘要翻译：描述了一种至少部分地在植入状态中的表面区域，其与硬和/或软组织的至少间接地相接触具有涂层的植入物。优选的植入物，其特征在于，两个他汀类药物如辛伐他汀的包衣，在选自支链或直链的，取代或未取代的选择的水解或未水解形式或药学上可接受的盐，和至少一种另外的组分，饱和或部分不饱和的 C10-C30烷基，烯基，烷基芳基，芳基，环烷基，烷基环烷基，Alkylcycloaryl胺或它们的混合物和/或含有至少一种水溶性离子聚合物组分。此外，制造这种植入物的方法被描述，以及其可以在这样的方法中使用的组合物。

3. 发明申请

WO2013131993A3 CHEWING GUM FOR THE DIAGNOSIS OF INFLAMMATORY TISSUES IN DENTAL APPLICATIONS 审中-公开
标题翻译：用于诊断牙科应用中炎症组织的凝胶
公开(公告)号：WO2013131993A3
公开(公告)日：2013-10-31
申请号：PCT/EP2013054569
申请日：2013-03-07
申请人： THOMMEN MEDICAL AG
发明人： SCHNABELRAUCH MATTHIAS , MEINEL LORENZ , SCHLOTTIG FALKO , WYRWA RALF
IPC分类号： A61K49/00 , A61C8/00
CPC分类号： A61K49/0004 , A23G4/14 , A61B5/14546 , A61B5/4552 , A61C19/04 , A61C2201/00 , A61C2201/002 , A61K9/0058 , A61K49/0069 , C12Q1/04 , C12Q1/37 , C12Q2304/00 , G01N33/528 , G01N33/68 , G01N33/6893 , G01N2333/96494 , G01N2800/18
摘要： The document proposes a diagnostic chewing gum for identifying the presence of inflammatory tissues in the mouth, in particular in or adjacent to the mandible, the maxilla, an implant or the teeth of a user, comprising a base material or particles (3) embedded and/or attached to said base material; an element (1, 5-7), like e.g. a releasable flavor molecule, attached to said base material and/or said particles, for the generation of a change in the chewing gum directly detectable by the user; wherein the element (1, 5-7) generates the change upon direct or indirect contact with a marker (4), e.g. a proteolytic enzyme, which is released by inflammatory tissue in response to bacterial mediators.
摘要翻译：该文件提出了一种诊断口香糖，用于鉴定口中，特别是在下颌骨，上颌骨，植入物或使用者的牙齿中或附近的炎症组织的存在，其包括基材或颗粒（3） /或附着在所述基材上; 元素（1，5-7），例如附着在所述基材和/或所述颗粒上的可释放风味分子，用于产生用户可直接检测的口香糖的变化; 其中所述元件（1,57）在与标记（4）直接或间接接触时产生变化，例如，一种蛋白水解酶，其由炎症组织响应于细菌介质释放。

4. 发明申请

WO2013131994A3 COATING FOR THE DIAGNOSIS OF INFLAMMATORY TISSUES IN DENTAL APPLICATIONS 审中-公开
标题翻译：涂层用于牙科应用中的炎性组织的诊断
公开(公告)号：WO2013131994A3
公开(公告)日：2013-10-31
申请号：PCT/EP2013054571
申请日：2013-03-07
申请人： THOMMEN MEDICAL AG
发明人： SCHLOTTIG FALKO , SCHNABELRAUCH MATTHIAS , MEINEL LORENZ , WYRWA RALF
IPC分类号： A61K49/00 , A61C8/00
CPC分类号： A61K49/0004 , A61B5/14546 , A61B5/4552 , A61C8/0013
摘要： The document proposes a coating for a fixed dental device, in particular for a dental implant, for a dental abutment, for a dental abutment screw and/or for a dental crown (as well as a device provided with such a coating) for identifying the presence of inflammatory tissues in the mouth, in particular adjacent to said device, comprising a base material or particles (3) embedded and/or attached to said base material; an element (1, 5-7) attached to said base material and/or said particles for the generation of a change in the coating directly detectable by the user; wherein the element (1, 5-7) generates the change upon direct or indirect contact with a marker (4) which is released by inflammatory tissue in response to bacterial mediators.
摘要翻译：该文献提出了用于固定牙科装置，特别是用于牙科植入物，用于牙科基台，用于牙科基台螺钉和/或用于牙冠的涂层（以及提供有这样的涂层的装置），用于识别特别是在所述装置附近的口腔中存在炎性组织，所述炎性组织包含嵌入和/或附着于所述基底材料的基底材料或颗粒（3）附着到所述基底材料和/或所述颗粒上的元件（1,5-7），用于产生可由使用者直接检测的涂层的变化; 其中元件（1,5-7）在与标记物（4）直接或间接接触时产生变化，标记物（4）响应于细菌介质而被炎性组织释放。

5. 发明申请

WO2008074175A3 BIOACTIVE IMPLANT COATING 审中-公开
标题翻译：生物活性涂层种植体
公开(公告)号：WO2008074175A3
公开(公告)日：2009-03-26
申请号：PCT/CH2007000637
申请日：2007-12-17
申请人： THOMMEN MEDICAL AG , BAYER ULRICH , SCHMIDT JUERGEN , HENNING ANGELIKA , KAUTZ ARMIN REX , WEISSER JUERGEN , SCHNABELRAUCH MATTHIAS , SCHLOTTIG FALKO
发明人： BAYER ULRICH , SCHMIDT JUERGEN , HENNING ANGELIKA , KAUTZ ARMIN REX , WEISSER JUERGEN , SCHNABELRAUCH MATTHIAS , SCHLOTTIG FALKO
IPC分类号： A61L27/30 , A61C8/00 , A61F2/28 , A61L27/06 , A61L27/54
CPC分类号： A61C8/0012 , A61F2/30767 , A61F2/3094 , A61F2002/3092 , A61F2310/00598 , A61F2310/00796 , A61L27/06 , A61L27/30 , A61L27/306 , A61L27/54 , A61L2300/414 , A61L2400/18
摘要： Disclosed is a method for coating a medical implant, particularly a metal-based dental implant, as well as an implant that can be produced by means of said method. The disclosed method is characterized in that the implant is dipped into an (aqueous) (electrolyte) solution comprising strontium ions at least in an area exposed to the bone in the implanted state, and the coating is formed in a plasma-chemical preferably electrolytic oxidation process.
摘要翻译：公开了一种用于涂覆医疗植入物，特别是方法的牙科植入物的基于金属的，以及与该方法中，植入物的帮助下生产。该方法的特征在于，所述植入物是至少在植入状态的暴露骨的范围（水溶液）（电解质）浸入用锶离子的溶液，并形成为优选的化合物的等离子体化学阳极氧化涂层。

6. 发明申请

WO2006131010A3 DENTAL IMPLANT AND METHOD FOR THE PRODUCTION THEREOF 审中-公开
标题翻译：假牙和方法及其
公开(公告)号：WO2006131010A3
公开(公告)日：2007-04-05
申请号：PCT/CH2006000296
申请日：2006-06-01
申请人： THOMMEN MEDICAL AG , SCHLOTTIG FALKO , HEFTI THOMAS
发明人： SCHLOTTIG FALKO , HEFTI THOMAS
IPC分类号： A61L27/56 , A61L27/10
CPC分类号： A61L27/56 , A61L27/10
摘要： The invention relates to a ceramic implant, especially a dental implant, comprising a structured or porous surface for at least partially inserting into a bone. An especially advantageous surface is obtained when it is at least partially modified by a salt melt. These excellent osteointegration properties can be obtained by a method whereby the surface is modified in a salt melt at least in the regions exposed to the bones and/or soft tissue, optionally following a previous modification of the surface whereby material has been removed.
摘要翻译：本发明公开了一种陶瓷的植入物，特别是牙科植入物，具有凹凸，RESP。多孔表面用于至少部分地插入骨。一种特别有利的多孔表面时，可以使用它是至少部分地熔融盐改性。这些优异的骨整合性质可以在一个过程，其中，任选地事先烧蚀表面改性后，至少在暴露于该表面上的骨和/或软组织的区域是表面改性的盐熔体引起。

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