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1. 发明申请

WO2003095086A2 FLUID REACTOR 审中-公开
标题翻译：流体反应器
公开(公告)号：WO2003095086A2
公开(公告)日：2003-11-20
申请号：PCT/GB2003/001993
申请日：2003-05-09
申请人： THE UNIVERSITY OF DURHAM , CHAMBERS, Richard, Dickinson , HOLLING, Darren , SANDFORD, Graham
发明人： CHAMBERS, Richard, Dickinson , HOLLING, Darren , SANDFORD, Graham
IPC分类号： B01J19/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/0086 , B01J2219/00869 , B01J2219/00961 , B01J2219/00963 , B01L3/5027
摘要： A reactor for carrying out a reaction between at least two fluids comprises a reactor plate (20) with a plurality of grooves or through slots (22) in which the fluids mix and react and a separable overlying reservoir plate (2) for supplying the fluids to slots (22) from reservoirs (4, 6) via slots (10) a, (10) b, with a collecting conduit or reservoir (8) and slots (10) c for the product of the reaction. Reservoir plate (2) may lie between two reactor plates, or a single reactor plate (20) may lie between two reservoir plates. Third or further reservoirs may or may not be spaced from the second reservoir (6) depending on whether more than two fluids need to be present simultaneously, or whether a second reaction is required after the first two fluids have had time to react. Means may be provided for controlling the pressure in slots (22), the pressure differential (and flow rate) along slot (22), and/or the temperature in the reservoirs (4, 6) or slots (22). Multiple reactors may be coupled in parallel/series for scaling up or for performing plural or progressive reactions (such as perfluorination).
摘要翻译：用于在至少两种流体之间进行反应的反应器包括具有多个槽的反应器板（20）或通过槽（22），流体混合和反应的反应器板（20）和用于供应流体的可分离的上部储存器板（2）通过槽（10）a，（10）b与储存器（4,6）的槽（22）与收集管道或储存器（8）和用于反应产物的槽（10）c相连。储层板（2）可以位于两个反应器板之间，或者单个反应器板（20）可以位于两个储存器板之间。取决于是否需要同时存在多于两种的流体，或者在前两种流体有时间反应之后是否需要第二反应，第三或另外的储存器可以或可以不与第二储存器（6）间隔开。可以提供用于控制槽（22）中的压力，沿着槽（22）的压力差（和流速）和/或储存器（4,6）或槽（22）中的温度的装置。多个反应器可以并联/串联以进行放大或用于进行多个或逐步反应（例如全氟化）。

2. 发明申请

WO2003095086A3 FLUID REACTOR 审中-公开
公开(公告)号：WO2003095086A3
公开(公告)日：2003-11-20
申请号：PCT/GB2003/001993
申请日：2003-05-09
申请人： THE UNIVERSITY OF DURHAM , CHAMBERS, Richard, Dickinson , HOLLING, Darren , SANDFORD, Graham
发明人： CHAMBERS, Richard, Dickinson , HOLLING, Darren , SANDFORD, Graham
IPC分类号： B01J19/00
摘要： A reactor for carrying out a reaction between at least two fluids comprises a reactor plate (20) with a plurality of grooves or through slots (22) in which the fluids mix and react and a separable overlying reservoir plate (2) for supplying the fluids to slots (22) from reservoirs (4, 6) via slots (10) a, (10) b, with a collecting conduit or reservoir (8) and slots (10) c for the product of the reaction. Reservoir plate (2) may lie between two reactor plates, or a single reactor plate (20) may lie between two reservoir plates. Third or further reservoirs may or may not be spaced from the second reservoir (6) depending on whether more than two fluids need to be present simultaneously, or whether a second reaction is required after the first two fluids have had time to react. Means may be provided for controlling the pressure in slots (22), the pressure differential (and flow rate) along slot (22), and/or the temperature in the reservoirs (4, 6) or slots (22). Multiple reactors may be coupled in parallel/series for scaling up or for performing plural or progressive reactions (such as perfluorination).

3. 发明申请

WO2015181545A1 CYCLISING PEPTIDES 审中-公开
标题翻译：循环肽
公开(公告)号：WO2015181545A1
公开(公告)日：2015-12-03
申请号：PCT/GB2015/051543
申请日：2015-05-28
申请人： THE UNIVERSITY OF DURHAM
发明人： COBB, Steven , COXON, Christopher , SANDFORD, Graham
IPC分类号： C07K1/113 , C07K1/08 , C07K1/107
CPC分类号： C07K1/088 , C07K1/084 , C07K1/1072 , C07K1/113 , C07K7/52
摘要： A method for preparing a cyclic peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to cyclise the peptide, derivative or analogue thereof.
摘要翻译：描述了制备环肽，其衍生物或类似物的方法。该方法包括使肽，其衍生物或类似物与氟 - 杂芳族化合物接触以使肽，衍生物或类似物环化。

4. 发明申请

WO2015181544A2 CHEMICALLY MODIFYING PEPTIDES 审中-公开
标题翻译：化学修饰肽
公开(公告)号：WO2015181544A2
公开(公告)日：2015-12-03
申请号：PCT/GB2015/051542
申请日：2015-05-28
申请人： THE UNIVERSITY OF DURHAM
发明人： COBB, Steven , COXON, Christopher , SANDFORD, Graham
IPC分类号： C07K1/113
CPC分类号： C07K1/1077 , C07K1/02 , C07K1/084 , C07K1/088 , C07K1/1072 , C07K1/113
摘要： A method for chemically modifying a peptide, derivative or analogue thereof is described. The method comprises contacting a peptide, derivative or analogue thereof with a fluoro-heteroaromatic compound to activate the peptide, derivative or analogue thereof. The activated peptide, derivative or analogue thereof is then contacted with a nucleophile or base to create a chemically modified peptide, derivative or analogue thereof.
摘要翻译：描述了用于化学修饰其肽，衍生物或类似物的方法。该方法包括使肽，其衍生物或类似物与氟 - 杂芳族化合物接触以活化其肽，衍生物或类似物。然后将活化的肽，其衍生物或类似物与亲核试剂或碱基接触以产生化学修饰的肽，其衍生物或类似物。

5. 发明申请

WO2007112985A1 A COMPOSITION COMPRISING AT LEAST ONE TYPE OF LIQUID CRYSTAL 审中-公开
标题翻译：包含至少一种类型的液晶的组合物
公开(公告)号：WO2007112985A1
公开(公告)日：2007-10-11
申请号：PCT/EP2007/002902
申请日：2007-03-30
申请人： SONY DEUTSCHLAND GMBH , KILICKIRAN, Pinar , MASUTANI, Akira , ROBERTS, Anthony , NELLES, Gabriele , YASUDA, Akio , TADEUSIAK, Andrzej , SANDFORD, Graham
发明人： KILICKIRAN, Pinar , MASUTANI, Akira , ROBERTS, Anthony , NELLES, Gabriele , YASUDA, Akio , TADEUSIAK, Andrzej , SANDFORD, Graham
IPC分类号： C09K19/54
CPC分类号： C09K19/54 , Y10T428/10 , Y10T428/1036
摘要： The present invention relates to a composition comprising at least one type of liquid crystal, to a liquid crystal cell and liquid crystal display device comprising such composition and to a method of preparing such a composition and/or such a liquid crystal cell.
摘要翻译：本发明涉及包含至少一种液晶的组合物，液晶单元和包含这种组合物的液晶显示装置，以及制备这种组合物和/或这种液晶盒的方法。

6. 发明申请

WO2009030928A2 A PROCESS FOR MAKING AND USING HOF.RCN 审中-公开
标题翻译：制作和使用HOF.RCN的过程
公开(公告)号：WO2009030928A2
公开(公告)日：2009-03-12
申请号：PCT/GB2008/003018
申请日：2008-09-05
申请人： THE SECRETARY OF STATE FOR DEFENCE , MURRAY, Christopher , SANDFORD, Graham
发明人： MURRAY, Christopher , SANDFORD, Graham
CPC分类号： C07B33/00 , B01J19/0093 , B01J2219/00867 , B01J2219/00891
摘要： The invention relates to a process for making HOF.RCN and using it to oxidise organic substrates in a quick and safe way. The process comprises passing diluted fluorine through a conduit and RCN in water through another conduit into a microreactor to form HOF.RCN and reacting this with an organic substrates.
摘要翻译：本发明涉及一种制备HOF.RCN的方法，并使用它以快速和安全的方式氧化有机基材。该方法包括将稀释的氟通过导管和RCN在水中通过另一导管进入微反应器以形成HOF.RCN并使其与有机底物反应。

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