专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2013086636A1 SOLUBLE IGF RECEPTOR FC FUSION PROTEINS AND USES THEREOF 审中-公开
标题翻译：可溶性IGF受体FC融合蛋白及其用途
公开(公告)号：WO2013086636A1
公开(公告)日：2013-06-20
申请号：PCT/CA2012/050899
申请日：2012-12-14
申请人： THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY , NATIONAL RESEARCH COUNCIL OF CANADA
发明人： BRODT, Pnina , MASSIE, Bernard , SULEA, Traian
IPC分类号： C12N15/62 , A61K47/48 , A61P35/00 , A61P35/04 , C07K14/71 , C07K16/00 , C07K19/00 , C12N15/63 , A61K35/28
CPC分类号： C07K14/71 , A61K35/28 , A61K38/00 , A61K39/3955 , A61K45/06 , A61K48/00 , A61K2035/124 , A61K2039/505 , A61K2039/515 , C07K14/72 , C07K16/22 , C07K2319/01 , C07K2319/21 , C07K2319/30
摘要： There are described herein novel soluble IGF receptor Fc fusion proteins and compositions and methods of use thereof for treating angiogenesis associated disorders and malignant disease, such as cancer and metastasis, wherein the fusion proteins bind specifically to IGF-1 or IGF-2.
摘要翻译：本文描述了新颖的可溶性IGF受体Fc融合蛋白及其用于治疗血管生成相关疾病和恶性疾病如癌症和转移的组合物及其使用方法，其中所述融合蛋白特异性结合IGF-1或IGF-2。

2. 发明申请

WO2022115946A1 THERAPEUTIC APPLICATIONS OF TYPE 1 INSULIN-LIKE GROWTH FACTOR (IGF-1) RECEPTOR ANTAGONISTS 审中-公开
公开(公告)号：WO2022115946A1
公开(公告)日：2022-06-09
申请号：PCT/CA2021/051714
申请日：2021-12-01
申请人： THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
发明人： BRODT, Pnina
IPC分类号： A61K47/68 , A61K38/30 , A61K39/395 , A61P35/00 , A61P35/04 , A61P37/02 , C07K14/72 , C07K16/28 , C07K19/00
摘要： The present disclosure concerns the reduction in the immunosuppression and the increase in the anti-tumor immune cytotoxicity in a tissue by using an antagonist of the type 1 insulin growth factor receptor (IGF-1R). The present disclosure also concerns the combination of the antagonist of the IGF-1R with an an immune response activating agent to mitigate the symptom or treat a cancer in a subject.

3. 发明申请

WO2010012088A1 APPARATUS AND METHOD FOR LOADING AND TRANSPORTING CONTAINERS 审中-公开
标题翻译：装载和运输集装箱的装置和方法
公开(公告)号：WO2010012088A1
公开(公告)日：2010-02-04
申请号：PCT/CA2009/001060
申请日：2009-07-28
申请人： THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY , BRODT, Pnina , YOU, Zhipeng
发明人： BRODT, Pnina , YOU, Zhipeng
IPC分类号： A61K38/30 , A61K35/12 , A61K35/28 , A61K48/00 , A61P35/00 , A61P35/04
CPC分类号： C07K14/005 , A61K35/35 , A61K38/30 , A61K48/00 , C12N2740/16122
摘要： Apparatus and methods for loading, transporting and dumping a plurality of containers on a vehicle are provided. The apparatus includes a frame pivotally attachable a vehicle bed, an upper container engaging means and a lower container engaging means, both coupled to the frame. The upper container engaging means is moveable between a first height and a second height, the first height and the second height differing by greater than at least the height of a container. The lower container engaging means may be stowed and deployed. The upper container engaging means is moveable to the first height for loading a first container when the lower container engaging means is stowed. The lower container engaging means is deployed at the first height for loading the second container when the upper container engaging means is at the second height. The first container and second container may thereby be sequentially loaded and simultaneously transported on the vehicle.
摘要翻译：提供了用于在车辆上装载，运输和倾倒多个容器的装置和方法。该装置包括可枢转地附接到车床的框架，上部容器接合装置和下部容器接合装置，两者都联接到框架。上容器接合装置可在第一高度和第二高度之间移动，第一高度和第二高度至少高于容器的高度。下容器接合装置可以被收起和展开。当下部容器接合装置被收起时，上部容器接合装置可移动到用于装载第一容器的第一高度。当上部容器接合装置处于第二高度时，下容器接合装置展开在第一高度处以装载第二容器。因此，第一容器和第二容器可以依次装载并同时在车辆上运输。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式