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1. 发明申请

WO2004037184A2 METHODS FOR THE TREATMENT OF SKIN DISORDERS 审中-公开
标题翻译：治疗皮肤病的方法
公开(公告)号：WO2004037184A2
公开(公告)日：2004-05-06
申请号：PCT/US2003/033415
申请日：2003-10-22
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K
CPC分类号： A61K45/06 , A61K8/42 , A61K8/4913 , A61K8/498 , A61K8/4986 , A61K8/602 , A61K8/67 , A61K8/676 , A61K8/678 , A61K8/922 , A61K8/97 , A61K9/0014 , A61K31/353 , A61K31/385 , A61K31/7048 , A61K36/185 , A61K36/254 , A61K36/258 , A61K36/736 , A61K36/82 , A61K41/00 , A61K47/10 , A61K2800/522 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61K2300/00
摘要： Methods for the reduction, treatment or partial prevention of reactive and inflammatory dermatoses, including eczema and psoriasis, are provided. The methods comprise administering a composition that includes one or more flavonoids and is optionally formulated in a pharmaceutically acceptable carrier. Also provided are methods of facilitating the healing of wounds, and of cleansing, beautifying, and improving the cosmetic appearance of the skin. Further optional ingredients may be added to the composition used in the present invention, such as non-flavonoid antioxidants, and one or more compounds that regulate cell differentiation and/or cell proliferation. The composition may be administered as a topical composition.
摘要翻译：提供了减少，治疗或部分预防包括湿疹和牛皮癣在内的反应性和炎症性皮肤病的方法。该方法包括施用包含一种或多种类黄酮并任选配制在药学上可接受的载体中的组合物。还提供促进伤口愈合，清洁，美化和改善皮肤美容外观的方法。其他任选成分可以加入到用于本发明的组合物中，例如非类黄酮抗氧化剂，以及一种或多种调节细胞分化和/或细胞增殖的化合物。该组合物可以作为局部组合物给药。

2. 发明申请

WO2006065889A3 COMPOSITIONS AND METHODS FOR REDUCING THE TRANSMISSIVITY OF ILLNESSES 审中-公开
公开(公告)号：WO2006065889A3
公开(公告)日：2006-06-22
申请号：PCT/US2005/045218
申请日：2005-12-14
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： C12Q1/70
摘要： Methods for prophylactic and anti-transmissivity uses of an anti-microbial composition are disclosed. The method comprise the step of administering to a mammal or a bird, and amount of a composition having a first ingredient obtainable from ginger; a second ingredient obtainable from green tea; an optional third ingredient obtainable from turmeric; andan acceptable carrier. When administered the composition is effective to reduce the incidence of contracting an illness or to prophylactically prevent transmission of an illness. Also disclosed are nasal and throat spray compositions for use in the methods of the invention.

3. 发明申请

WO2003053336A2 METHODS FOR THE TREATMENT OF PERIPHERAL NEURAL AND VASCULAR AILMENTS 审中-公开
标题翻译：治疗外周神经和血管病的方法
公开(公告)号：WO2003053336A2
公开(公告)日：2003-07-03
申请号：PCT/US2002/035654
申请日：2002-11-06
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K
CPC分类号： A61Q19/08 , A61K8/355 , A61K8/42 , A61K8/4913 , A61K8/498 , A61K8/4986 , A61K8/602 , A61K8/64 , A61K8/671 , A61K8/676 , A61K8/678 , A61K8/97 , A61K31/07 , A61K31/352 , A61K31/353 , A61K31/355 , A61K31/375 , A61K31/7048 , A61K36/82 , A61K2800/522 , A61Q7/00 , A61Q19/00 , A61K2300/00
摘要： Compositions and methods for the treatment of peripheral neuraland vascular ailments are disclosed. The method comprises administering a flavonoid compound with antioxidant properties, optionally formulated in a pharmaceutically acceptable carrier. This compound or combination of compounds provides significant, effective relief of the symptoms of peripheral neural or vascular ailments. In addition, the compositions, when used according to the methods of the present invention, do not exhibit the severe side effects of many prior art compositions proposed for treatment of these ailments.
摘要翻译：公开了治疗周围神经和血管疾病的组合物和方法。该方法包括施用具有抗氧化性质的类黄酮化合物，任选地配制在药学上可接受的载体中。这种化合物或化合物的组合提供了显着的，有效的缓解周围神经或血管疾病的症状。此外，当根据本发明的方法使用时，组合物不表现出许多提出用于治疗这些疾病的现有技术组合物的严重副作用。

4. 发明申请

WO2003053336A3 METHODS FOR THE TREATMENT OF PERIPHERAL NEURAL AND VASCULAR AILMENTS 审中-公开
公开(公告)号：WO2003053336A3
公开(公告)日：2003-07-03
申请号：PCT/US2002/035654
申请日：2002-11-06
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K31/35
摘要： Compositions and methods for the treatment of peripheral neuraland vascular ailments are disclosed. The method comprises administering a flavonoid compound with antioxidant properties, optionally formulated in a pharmaceutically acceptable carrier. This compound or combination of compounds provides significant, effective relief of the symptoms of peripheral neural or vascular ailments. In addition, the compositions, when used according to the methods of the present invention, do not exhibit the severe side effects of many prior art compositions proposed for treatment of these ailments.

5. 发明申请

WO2003013428A3 NUTRITIONAL SUPPLEMENTS AND METHODS OF USING SAME 审中-公开
公开(公告)号：WO2003013428A3
公开(公告)日：2003-02-20
申请号：PCT/US2002/024794
申请日：2002-08-06
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K9/20
摘要： A nutritional supplement for providing, and for promoting the health of salivary glands and/or supporting normal or healthy swallowing includes ingredients obtainable from turmeric, ginger, and horseradish. The nutritional supplement may also be used to treat symptoms such as symptoms of a common cold, sore throat, congestion, mucositis, laryngitis, mucous membrane inflammation and sialorrhea, as well as inflammation and viral infectin, or to inhibit or exterminate a virus. This nutritional supplement can be orally administered a person. The nutritional supplement may further include optional ingredients such as ingredients obtainable from slippery elm bark powder and green tea, as well as other optional ingredients. This nutritional supplement may further include a pharmaceutically acceptable carrier for oral administration. Also disclosed are methods of providing nutrition, for promoting the health of salivary glands and/or supporting normal or healthy swallowing, as well as methods for treating symptoms of a common cold, sore throat, congestion, mucositis, laryngitis, mucous membrane inflammation and sialorrhea. Methods of treating inflammation, and viral infections, as well as inhibiting or exterminating viruses are also disclosed.

6. 发明申请

WO2007038506A2 METHOD FOR THE TREATMENT OF CACHEXIA 审中-公开
标题翻译：治疗慢性乙型肝炎的方法
公开(公告)号：WO2007038506A2
公开(公告)日：2007-04-05
申请号：PCT/US2006/037469
申请日：2006-09-27
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K36/906 , A61K36/82 , A61K36/31
CPC分类号： C07D209/42 , Y02P20/55
摘要： A method for treatment of cachexia and or alleviating one or more symptoms of cachexia involving the step of administering, to a human or animal, a composition including ingredients obtainable from turmeric, ginger, green tea, and, optionally, horseradish. This composition may further include a pharmaceutically acceptable carrier.
摘要翻译：一种用于治疗恶病质和/或减轻一种或多种恶病质症状的方法，其涉及向人或动物施用包含可从姜黄，姜，绿茶和任选地辣根获得的成分的组合物的步骤。该组合物还可以包括药学上可接受的载体。

7. 发明申请

WO2003051287A3 TOPICAL COMPOSITIONS AND METHODS FOR TREATMENT OF ADVERSE EFFECTS OF IONIZING RADIATION 审中-公开
公开(公告)号：WO2003051287A3
公开(公告)日：2003-06-26
申请号：PCT/US2002/035701
申请日：2002-11-06
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K31/59
摘要： Compositions and methods for the prevention, reduction or treatment of adverse effects due to exposure to ionizing radiation, including at least one flavonoid and at least one non-flavonoid antioxidant, optionally formulated in a acceptable carrier for a topical composition. The composition of the present invention may further include optional ingredients such as selenium, selenium compounds, anti-inflammatories, organic germanium compounds, compounds that regulate cell differentiation, Korean ginseng, American ginseng, Siberian ginseng and B-complex vitamins. A method for the topical administration of the composition in accordance with the present invention for the purpose of reducing, treating or preventing adverse effects caused by ionizing radiation involves topically administering a safe and effective amount of the composition of the invention an area of skin, which has been, is being or will be exposed to ionizing radiation. The compositions and methods can be employed to reduce, treat or prevent radiation injury caused by a wide variety of types of exposure to ionizing radiation.

8. 发明申请

WO2003051287A2 TOPICAL COMPOSITIONS AND METHODS FOR TREATMENT OF ADVERSE EFFECTS OF IONIZING RADIATION 审中-公开
标题翻译：用于治疗放射性不良影响的局部组合物和方法
公开(公告)号：WO2003051287A2
公开(公告)日：2003-06-26
申请号：PCT/US2002/035701
申请日：2002-11-06
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K
CPC分类号： A61K9/0014 , A61K8/42 , A61K8/4913 , A61K8/498 , A61K8/4986 , A61K8/602 , A61K8/67 , A61K8/676 , A61K8/678 , A61K8/922 , A61K8/97 , A61K31/353 , A61K31/385 , A61K31/7048 , A61K36/254 , A61K36/258 , A61K36/82 , A61K41/00 , A61K45/06 , A61K47/10 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61K2300/00
摘要： Compositions and methods for the prevention, reduction or treatment of adverse effects due to exposure to ionizing radiation, including at least one flavonoid and at least one non-flavonoid antioxidant, optionally formulated in a acceptable carrier for a topical composition. The composition of the present invention may further include optional ingredients such as selenium, selenium compounds, anti-inflammatories, organic germanium compounds, compounds that regulate cell differentiation, Korean ginseng, American ginseng, Siberian ginseng and B-complex vitamins. A method for the topical administration of the composition in accordance with the present invention for the purpose of reducing, treating or preventing adverse effects caused by ionizing radiation involves topically administering a safe and effective amount of the composition of the invention an area of skin, which has been, is being or will be exposed to ionizing radiation. The compositions and methods can be employed to reduce, treat or prevent radiation injury caused by a wide variety of types of exposure to ionizing radiation.
摘要翻译：用于预防，减少或治疗由于暴露于电离辐射引起的不利影响的组合物和方法，包括至少一种类黄酮和至少一种非类黄酮抗氧化剂，任选地配制在局部组合物的可接受载体中。本发明的组合物还可以包括任选的成分，例如硒，硒化合物，抗炎剂，有机锗化合物，调节细胞分化的化合物，韩国人参，西洋参，西伯利亚人参和B复合维生素。为了减少，治疗或预防由电离辐射引起的不良反应，本发明的组合物的局部施用方法包括局部施用本发明组合物的安全有效量的皮肤区域，其中已经或将要暴露于电离辐射。组合物和方法可用于减少，治疗或预防由各种各样的暴露于电离辐射的类型引起的辐射损伤。

9. 发明申请

WO2003039452A3 NUTRITIONAL SUPPLEMENTS AND METHODS FOR PREVENTION, REDUCTION AND TREATMENT OF RADIATION INJURY 审中-公开
公开(公告)号：WO2003039452A3
公开(公告)日：2003-05-15
申请号：PCT/US2002/013526
申请日：2002-05-01
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K31/59
摘要： A nutritional supplement composition for the prevention, reduction or treatment of radiation injury due to exposure to ionizing radiation, including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants, optionally formulated in a pharmaceutically acceptable carrier for an oral composition. The composition of the present invention may further include optional ingredients such as flavonoids, flavonoid derivatives, selenium, selenium compounds, anti-inflammatories, organic germanium, Korean ginseng, American ginseng, Siberian ginseng and B-complex vitamins. A method for the administration of an oral composition for the purpose of preventing, reducing or treating radiation injury involves orally administering an effective amount of a composition including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants to a person before, during or after radiation exposure. A method for the topical administration of the composition in accordance with the present invention for the purpose of preventing, reducing or treating radiation injury involves topically administering an effective amount of the composition of the invention an area of skin, which has been or will be exposed to ionizing radiation. The compositions and methods can be employed to prevent, reduce or treat radiation injury caused by a wide variety of types of radiation exposure.

10. 发明申请

WO2003039452A2 NUTRITIONAL SUPPLEMENTS AND METHODS FOR PREVENTION, REDUCTION AND TREATMENT OF RADIATION INJURY 审中-公开
标题翻译：营养补充和预防，减少和治疗辐射伤害的方法
公开(公告)号：WO2003039452A2
公开(公告)日：2003-05-15
申请号：PCT/US2002/013526
申请日：2002-05-01
申请人： THE QUIGLEY CORPORATION , ROSENBLOOM, Richard, A.
发明人： ROSENBLOOM, Richard, A.
IPC分类号： A61K
CPC分类号： A61K9/0014 , A61K8/42 , A61K8/4913 , A61K8/498 , A61K8/4986 , A61K8/602 , A61K8/67 , A61K8/676 , A61K8/678 , A61K8/922 , A61K8/97 , A61K31/353 , A61K31/385 , A61K31/7048 , A61K36/254 , A61K36/258 , A61K36/82 , A61K41/00 , A61K45/06 , A61K47/10 , A61Q17/00 , A61Q17/04 , A61Q19/00 , A61Q19/004 , A61K2300/00
摘要： A nutritional supplement composition for the prevention, reduction or treatment of radiation injury due to exposure to ionizing radiation, including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants, optionally formulated in a pharmaceutically acceptable carrier for an oral composition. The composition of the present invention may further include optional ingredients such as flavonoids, flavonoid derivatives, selenium, selenium compounds, anti-inflammatories, organic germanium, Korean ginseng, American ginseng, Siberian ginseng and B-complex vitamins. A method for the administration of an oral composition for the purpose of preventing, reducing or treating radiation injury involves orally administering an effective amount of a composition including one or more compounds that regulates cell differentiation and/or cell proliferation, and one or more antioxidants to a person before, during or after radiation exposure. A method for the topical administration of the composition in accordance with the present invention for the purpose of preventing, reducing or treating radiation injury involves topically administering an effective amount of the composition of the invention an area of skin, which has been or will be exposed to ionizing radiation. The compositions and methods can be employed to prevent, reduce or treat radiation injury caused by a wide variety of types of radiation exposure.
摘要翻译：一种营养补充剂组合物，用于预防，减少或治疗由于暴露于电离辐射引起的辐射损伤，包括一种或多种调节细胞分化和/或细胞增殖的化合物，以及一种或多种抗氧化剂，任选地配制在药学上可接受的载体中一种口服组合物。本发明的组合物还可以包括任选的成分，例如类黄酮，类黄酮衍生物，硒，硒化合物，抗炎剂，有机锗，韩国人参，西洋参，西伯利亚人参和B复合维生素。为了防止，减少或治疗放射性损伤的口服组合物的给药方法包括口服施用有效量的包含一种或多种调节细胞分化和/或细胞增殖的化合物的组合物和一种或多种抗氧化剂，一个人在放射线之前，期间或之后。根据本发明的用于局部给予本发明组合物以防止，减少或治疗放射性损伤的方法涉及局部施用有效量的本发明组合物，该组合物已经或将被暴露的皮肤区域到电离辐射。组合物和方法可用于预防，减少或治疗由各种类型的辐射暴露引起的放射性损伤。

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