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1. 发明申请

WO2010017325A2 THERMALLY-ACTIVATABLE LIPOSOME COMPOSITIONS AND METHODS FOR IMAGING, DIAGNOSIS AND THERAPY 审中-公开
标题翻译：热激活脂肪组合物和成像，诊断和治疗方法
公开(公告)号：WO2010017325A2
公开(公告)日：2010-02-11
申请号：PCT/US2009/052895
申请日：2009-08-05
申请人： THE METHODIST HOSPITAL RESEARCH INSTITUTE , LI, King, Chuen , LI, Zheng , QIN, Guoting
发明人： LI, King, Chuen , LI, Zheng , QIN, Guoting
IPC分类号： A61K9/127
CPC分类号： A61K9/127 , A61K9/1273
摘要： Disclosed are thermally-activatable liposomal compositions and methods for their use in the formulation and administration of therapeutic, prophylactic, and diagnostic agents. The disclosed liposome structures are capable of carrying a variety of biologically active reagents, and permitting their controlled release in vivo by exploiting properties of their thermoregulatable lability.
摘要翻译：公开了可热活化的脂质体组合物及其用于制剂和给药治疗剂，预防剂和诊断剂的方法。所公开的脂质体结构能够携带各种生物活性试剂，并且通过利用它们的可热定性不稳定性质允许其在体内的受控释放。

2. 发明申请

WO2012103328A1 LABELED, NON- PEPTIDIC MULTIVALENT INTEGRIN ALPHA -V - BETA - 3 ANTAGONISTS, COMPOSITIONS CONTAINING THEM AND THEIR USE 审中-公开
标题翻译：标记的，非多肽多功能整合素ALPHA -V-BETA-3拮抗剂，包含它们的组合物及其使用
公开(公告)号：WO2012103328A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/022712
申请日：2012-01-26
申请人： THE METHODIST HOSPITAL RESEARCH INSTITUTE , LI, King Chuen , LI, Zheng , LI, Feng
发明人： LI, King Chuen , LI, Zheng , LI, Feng
IPC分类号： A61K31/00
CPC分类号： A61K49/0021 , A61K9/127 , A61K9/51 , A61K31/505 , A61K31/506 , A61K45/06 , A61K47/55 , A61K47/60 , A61K49/0052 , A61K51/0459 , C07D239/14 , C07D403/14
摘要： Disclosed are multivalent integrin receptor antagonists (including near-infrared [NIR], fluorescent, and/or radio-labeled, non-peptidic integrin α ν β 3 antagonist compositions), that are useful in a variety of therapeutic, prophylactic, and diagnostic imaging modalities, including for example, in the imaging, detection, localization, quantitation, and/or as agents in the prevention, treatment, and/or amelioration of symptoms of one or more diseases, including proliferative diseases such as cancer, in an affected animal, and particularly in affect mammals such as humans. In particular embodiments, fluorescently- or radio-labeled- non-peptidic, multivalent integrin α ν β 3 compounds are provided. Compositions including such compounds have been shown to have utility in detecting, localizing, quantitating, and/or imaging integrin alpha-nu-beta-3 receptor-expressing cells, including, for example, cancer cells in vitro , in vivo , or in situ .
摘要翻译：公开了多价整联蛋白受体拮抗剂（包括近红外[NIR]，荧光和/或放射性标记的非肽整联蛋白α3拮抗剂组合物），其可用于多种治疗，预防和诊断成像模式，包括例如成像，检测，定位，定量和/或在受影响的动物中预防，治疗和/或改善一种或多种疾病（包括增殖性疾病如癌症）的症状的药剂，特别是影响哺乳动物如人类。在特定实施方案中，提供了荧光或放射性标记的非肽，多价整联蛋白α3 3化合物。已经显示包含这些化合物的组合物可用于检测，定位，定量和/或成像整合素α-nu-β-3受体表达细胞，包括例如体外，体内或原位的癌细胞。

3. 发明申请

WO2021011151A2 BATTERY WITH SULFUR-CONTAINING ELECTRODE 审中-公开
公开(公告)号：WO2021011151A2
公开(公告)日：2021-01-21
申请号：PCT/US2020/038866
申请日：2020-06-21
申请人： ZHANG, Sanpei , LI, Zheng
发明人： ZHANG, Sanpei , LI, Zheng
IPC分类号： H01M10/0525 , H01M10/0562 , H01M4/485
摘要： A variety of batteries are provided having a sulfur-containing cathode; a metal anode; and an electrolyte between the cathode and the anode, wherein the electrolyte is capable of solvating metal ions produced from the metal anode, polysulfide species produced from the sulfurcontaining cathode, and dissolved oxygen species. In some aspects, the batteries include a separator separating the battery into a cathode region nearest the cathode and an anode region nearest the anode, wherein the separator permits permeability of the electrolyte and the metal ions. Methods of using and batteries are also provided. In some aspects, the batteries are capable of charge/discharge cycles in excess of 10, 100, or 1000 cycles.

4. 发明申请

WO2004086174A3 BATCH-BASED METHOD AND TOOL FOR GRAPHICAL MANIPULATION OF WORKFLOWS 审中-公开
公开(公告)号：WO2004086174A3
公开(公告)日：2004-10-07
申请号：PCT/US2004/007748
申请日：2004-03-11
申请人： TERANODE CORPORATION , ARNSTEIN, Lawrence, F. , LI, Zheng , HILL, John, M. , KELLEN, Michael, R. , POULAIN, Christophe , FANGER, Neil, A. , CHEN, Kuang
发明人： ARNSTEIN, Lawrence, F. , LI, Zheng , HILL, John, M. , KELLEN, Michael, R. , POULAIN, Christophe , FANGER, Neil, A. , CHEN, Kuang
IPC分类号： G06F3/00
摘要： An autofill algorithm provides tools for defining and automatically executing batch based procedures in an adaptive hierarchical workflow environment, and may be suitable for a large variety of applications including laboratory procedure planning, execution, documentation, as well as a driving robotic apparatus.

5. 发明申请

WO2015066555A1 VARIATION-TOLERANT WAVELENGTH DIVISION MULTIPLEXING RECEIVER AND TRANSCEIVER, AND ASSOCIATED METHODS 审中-公开
标题翻译：易变宽波段多路复用接收机和收发器及相关方法
公开(公告)号：WO2015066555A1
公开(公告)日：2015-05-07
申请号：PCT/US2014/063584
申请日：2014-10-31
申请人： THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE , MICKELSON, Alan , LI, Zheng , MOHAMED, Moustafa , CHEN, Xi
发明人： MICKELSON, Alan , LI, Zheng , MOHAMED, Moustafa , CHEN, Xi
IPC分类号： H04L25/06
CPC分类号： H04J14/0254 , H04B10/40 , H04B10/516 , H04B10/671 , H04B10/801
摘要： A variation-tolerant receiver includes a plurality of receiver resonators configured to demultiplex a multiplexed modulated signal received from at least one wavelength division multiplexing (WDM) transmitter having a plurality of transmitter resonators and wherein operationally each of the receiver resonators has a receiver resonance linewidth not exceeding a minimum spacing between two adjacent transmitter resonances of the transmitter resonators, the receiver resonances collectively spanning a free spectral range of one of the receiver resonators such that the variation-tolerant receiver achieves gapless spectral response. A method passively compensates transmitter-receiver channel mismatch in a transceiver by: separating a broadband carrier into a plurality of narrowband transmitter carriers; modulating the narrowband transmitter carriers to form a plurality of modulated signals; multiplexing each of the modulated signals to form a multiplexed modulated signal; and demultiplexing the multiplexed modulated signal onto a plurality of receiver channels.
摘要翻译：一种变形容限接收机包括多个接收机谐振器，其被配置为对从具有多个发射机谐振器的至少一个波分多路复用（WDM）发射机接收的复用调制信号进行解复用，并且其中每个接收机谐振器的接收机共振线宽不是超过发射机谐振器的两个相邻发射机谐振之间的最小间距，接收机谐振共同跨越一个接收机谐振器的自由频谱范围，使得变化容限接收机实现无缝隙频谱响应。一种方法，通过以下步骤被动地补偿收发信机中的发射机 - 接收机信道不匹配：将宽带载波分离成多个窄带发射机载波; 调制窄带发射机载波以形成多个调制信号; 复用每个调制信号以形成多路调制信号; 以及将多路复用的调制信号解复用到多个接收机信道上。

6. 发明申请

WO2014053072A1 RECREATIONAL VEHICLE BEAM SWITCH ASSEMBLY 审中-公开
标题翻译：娱乐车梁开关总成
公开(公告)号：WO2014053072A1
公开(公告)日：2014-04-10
申请号：PCT/CN2012/082518
申请日：2012-10-03
申请人： HONEYWELL INTERNATIONAL INC. , QIN, Lei , ZHU, Xiansi , LI, Zheng , DENG, Dongmei
发明人： QIN, Lei , ZHU, Xiansi , LI, Zheng , DENG, Dongmei
IPC分类号： H01H9/22 , H01H13/34 , B60Q1/00 , B60K37/06
CPC分类号： H01H9/223 , B60K37/06 , B60Q1/0076 , B60Q1/1453 , H01H9/06 , H01H13/56 , H01H2009/068
摘要： A switch assembly (108) includes a housing (202), a switch (204), a lock mechanism (206), and an input element (208). The switch (204) is disposed within the housing (202) and configured to translate, along a first axis (212), between a first switch position and a second switch position. The lock mechanism (206) is disposed within the housing (202) and configured to translate, along a second axis (216) that is parallel to the first axis (212), between an unlock position and a lock position. The input element (208) is coupled to the switch (204) and the lock mechanism (206) and is movable relative to the housing (202). The input element (208) is adapted to receive an input force and is configured, upon receipt thereof to selectively and simultaneously move the switch (204) and the lock mechanism (206) between the first and second switch positions and the unlock and lock positions, respectively.
摘要翻译：开关组件（108）包括壳体（202），开关（204），锁定机构（206）和输入元件（208）。开关（204）设置在壳体（202）内并且被构造成沿着第一轴线（212）在第一开关位置和第二开关位置之间平移。锁定机构（206）设置在壳体（202）内并被构造成沿着平行于第一轴线（212）的第二轴线（216）在解锁位置和锁定位置之间平移。输入元件（208）联接到开关（204）和锁定机构（206）并且可相对于壳体（202）移动。输入元件（208）适于接收输入力，并且在其被接收时被配置为选择性地并同时地将开关（204）和锁定机构（206）移动在第一和第二开关位置与解锁和锁定位置之间，分别。

7. 发明申请

WO2012163726A1 DISTRIBUTING L2 BASEBAND PROCESSING IN A RADIO NETWORK 审中-公开
标题翻译：在无线电网络中分配L2基带处理
公开(公告)号：WO2012163726A1
公开(公告)日：2012-12-06
申请号：PCT/EP2012/059451
申请日：2012-05-22
申请人： NOKIA SIEMENS NETWORKS OY , LI, Zheng , BERGLUND, Jan, Erik, Johan , SIPOLA, Jussi, Matti , RAMIREZ MONTALVO, Manuel, Enrique
发明人： LI, Zheng , BERGLUND, Jan, Erik, Johan , SIPOLA, Jussi, Matti , RAMIREZ MONTALVO, Manuel, Enrique
IPC分类号： H04W88/08
CPC分类号： H04W88/085 , H04W72/12 , H04W74/00
摘要： Functions for a data link layer are split between an access point and an access controller. The functions performed for uplink and downlink for the data link layer are some but not all of the functions performed by the data link layer to convert information between transport channels and radio bearers.
摘要翻译：数据链路层的功能在接入点和接入控制器之间分离。为数据链路层的上行链路和下行链路执行的功能是数据链路层执行的一些功能，但不是全部功能，用于在传输信道和无线电承载之间转换信息。

8. 发明申请

WO2012139295A1 METHOD AND APPARATUS FOR IMPLEMENTING HIGH-ORDER MODULATION SCHEMES USING LOW-ORDER MODULATORS 审中-公开
标题翻译：使用低阶调制器实现高阶调制方案的方法和装置
公开(公告)号：WO2012139295A1
公开(公告)日：2012-10-18
申请号：PCT/CN2011/072802
申请日：2011-04-14
申请人： ALCATEL LUCENT , ALCATEL-LUCENT SHANGHAI BELL CO., LTD. , LI, Zheng , ZHANG, Rong , CHEN, Guoyong , CLARK, Doug , CHEN, Hai , WAN, Yu , LENG, Jiaguan , SHELTON, Marc
发明人： LI, Zheng , ZHANG, Rong , CHEN, Guoyong , CLARK, Doug , CHEN, Hai , WAN, Yu , LENG, Jiaguan , SHELTON, Marc
IPC分类号： H04L27/36
CPC分类号： H03C5/00 , H04L27/0008 , H04L27/20 , H04L27/32
摘要： A processing device includes a plurality of modulators, the plurality of modulators performing modulation according to a first modulation scheme, a combiner configured to combine outputs from the plurality of modulators, and a signal processor configured to receive a bit stream and convert the bit stream into a plurality of input signals for the plurality of modulators such that the combiner generates a modulated output according to a second modulation scheme. The plurality of modulators may be low order modulators and a modulation schemes of the modulated output may include, for example, rotated quadrature phase shift keying (QPSK), pulse amplitude modulation (PAM), high order quadrature amplitude modulation (QAM), and multi-resolution high order quadrature amplitude modulation (M-QAM).
摘要翻译：处理装置包括多个调制器，所述多个调制器根据第一调制方案执行调制，组合器被配置为组合来自所述多个调制器的输出，以及信号处理器，被配置为接收比特流并将所述比特流转换成用于所述多个调制器的多个输入信号，使得所述组合器根据第二调制方案产生调制输出。多个调制器可以是低阶调制器，并且调制输出的调制方案可以包括例如旋转正交相移键控（QPSK），脉冲幅度调制（PAM），高阶正交幅度调制（QAM）和多 - 分辨率高阶正交幅度调制（M-QAM）。

9. 发明申请

WO2009138467A1 CHANNEL ALLOCATION PROCEDURE IN A MESHED NETWORK 审中-公开
标题翻译：渠道分配程序在网络中
公开(公告)号：WO2009138467A1
公开(公告)日：2009-11-19
申请号：PCT/EP2009/055853
申请日：2009-05-14
申请人： NOKIA SIEMENS NETWORKS OY , BERGLUND, Jan , LI, Zheng , TANG, Kevin
发明人： BERGLUND, Jan , LI, Zheng , TANG, Kevin
IPC分类号： H04W72/08
CPC分类号： H04W72/082
摘要： A method includes receiving at a gateway mesh node a channel set list indicating radio channels that are allowed for use by the gateway mesh node, scanning channels in the channel set list and creating a list of channels in order of interference that is present, allocating channels from the list of channels to a plurality of radios that comprise the gateway mesh node, and initiating transmission of beacon frames from each of the plurality of radios on a main channel. Each beacon frame includes information descriptive of a path cost representing a sum of all link costs back to a central point, a primary radio channel used by the radio transmitting the beacon frame, a channel set indicating only those channels that an associated portion of the mesh network is allowed to use, and a set of meshed nodes associated with the radio.
摘要翻译：一种方法包括在网关网状节点处接收指示被网关网节点允许使用的无线电信道的信道集列表，在信道集列表中扫描信道，并按存在的干扰顺序创建信道列表，分配信道从信道列表到包括网关网格节点的多个无线电，以及从主信道上的多个无线电装置中的每一个发起信标帧的发送。每个信标帧包括描述代表到中心点的所有链路成本的总和的路径成本的信息，由无线电发送信标帧使用的主无线电信道，仅指示那些信道的相关部分的信道集合网络被允许使用，以及一组与无线电相关联的网状节点。

10. 发明申请

WO2008004067A2 METHODS OF TREATMENT USING ALPHA-2-DELTA-1 SELECTIVE COMPOUNDS 审中-公开
标题翻译：使用ALPHA-2-DELTA-1选择性化合物治疗的方法
公开(公告)号：WO2008004067A2
公开(公告)日：2008-01-10
申请号：PCT/IB2007/001789
申请日：2007-06-29
申请人： PFIZER PRODUCTS INC. , LI, Zheng , SCHWARZ, Jacob Bradley
发明人： LI, Zheng , SCHWARZ, Jacob Bradley
IPC分类号： A61K31/185 , A61P25/08 , A61P25/22
CPC分类号： A61K31/185
摘要： The invention is directed to a method of treating a disorder or condition using an alpha-2-delta ligand with high affinity and selectivity for the alpha-2-delta-1 calcium channel subunit subtype. Administration of the alρha-2-delta-1 selective ligand, or a pharmaceutically acceptable salt, to a mammal, including a human, avoids or reduces the adverse effects compared to the administration of an alpha-2-delta non-selective ligand.
摘要翻译：本发明涉及使用对α-2-δ-1钙通道亚基亚型具有高亲和力和选择性的α-2-δ配体治疗病症或病症的方法。向哺乳动物（包括人）施用al-ha-2-δ-1选择性配体或药学上可接受的盐避免或减少与施用α-2-δ非选择性配体相比的不利影响。

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