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1. 发明申请

WO2011157299A1 IMPLANTABLE SENSOR DEVICE AND SYSTEM 审中-公开
标题翻译：可植入传感器装置和系统
公开(公告)号：WO2011157299A1
公开(公告)日：2011-12-22
申请号：PCT/EP2010/058624
申请日：2010-06-18
申请人： St. Jude Medical AB , HILL, Rolf , PERSSON, Torbjörn , STEGFELDT, Olof
发明人： HILL, Rolf , PERSSON, Torbjörn , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61B5/02055 , A61B5/01 , A61B5/0205 , A61B5/0215 , A61B5/1118 , A61B5/14532 , A61B5/14542 , A61B5/6848 , A61N1/0573 , A61N1/362 , A61N1/36564
摘要： The present invention relates generally to implantable medical devices and more particularly to implantable sensors, such as pressure sensors. The implantable medical device (10; 100) for measuring pressure is connectable to a medical lead (11; 111) and comprises an outer sheath (13; 113) and a helically shaped needle (14; 114) arranged at the outer sheath (13; 113). A pressure sensing body (15; 30; 40; 50; 60; 115) having a distal part (16; 36; 46; 56; 66; 116) is movably arranged in the outer sheath (13; 113). The pressure sensing body (15; 30; 40; 50; 60; 115) is arranged such that the distal part (16; 36; 46; 56; 66; 116) is located within the outer sheath (13; 113) in an initial state of the pressure sensing body (15; 30; 40; 50; 60; 115), wherein the pressure sensing body (15; 30; 40; 50; 60; 115) is arranged to be advanced from the initial state to protrude from the outer sheath (13; 113) and such that it is at least partially surrounded by the helically shaped needle (14; 114); and a pressure sensor (12, 34; 48; 58; 68) arranged at or adjacent to the distal part (16; 36; 46; 56; 66; 116) of the pressure sensing body (15; 30; 40; 50; 60; 115) for sensing pressure.
摘要翻译：本发明一般涉及可植入医疗装置，更具体地涉及可植入传感器，例如压力传感器。用于测量压力的可植入医疗装置（10; 100）可连接到医用引线（11; 111）并且包括外护套（13; 113）和布置在外鞘（13; 113）处的螺旋形针（14; 114） ; 113）。具有远端部分（16; 36; 46; 56; 66; 116）的压力感测体（15; 30; 40; 50; 60; 115）可移动地布置在外护套（13; 113）中。压力感测体（15; 30; 40; 50; 60; 115）被布置成使得远端部分（16; 36; 46; 56; 66; 116）位于外护套（13; 113）内，压力感测体（15; 30; 40; 50; 60; 115）的初始状态，其中所述压力感测体（15; 30; 40; 50; 60; 115）布置成从所述初始状态前进到突出并且使得其至少部分被螺旋形针（14; 114）包围; 以及压力传感器（12,34; 48; 58; 68），布置在所述压力感测体（15; 30; 40; 50; 50; 60; 115）用于感测压力。

2. 发明申请

WO2009070079A1 AN ACTIVE FIXATION HELIX AND A MEDICAL IMPLANTABLE LEAD 审中-公开
标题翻译：活动固定螺旋和医疗可植入式导管
公开(公告)号：WO2009070079A1
公开(公告)日：2009-06-04
申请号：PCT/SE2008/000639
申请日：2008-11-12
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof , JARL, Per, E.
发明人： HILL, Rolf , STEGFELDT, Olof , JARL, Per, E.
IPC分类号： A61N1/05 , A61B5/042
CPC分类号： A61N1/0573
摘要： The invention relates to an active fixation helix (2) for use as a tissue attaching element of a medical implantable lead and which is formed of a he- Nx wire (4), defining an inner diameter space confined by helix windings. The cross sectional dimension of the helix wire (4) is smaller in a direction in parallel to the longitudinal axis of the lead than in a direction transverse of the longitudinal axis of the lead. The invention also relates to a medical implantable lead comprising such an active fixation helix.
摘要翻译：本发明涉及用作医用可植入引线的组织附着元件的主动固定螺旋（2），并且由有效的螺旋线（4）形成，其限定由螺旋绕组限定的内径空间。螺旋线（4）的横截面尺寸在与引线的纵向轴线横向的方向上平行于引线的纵向轴线的方向上较小。本发明还涉及包括这种活性固定螺旋的医用可植入引线。

3. 发明申请

WO2009157818A1 A SET COMPRISING A MEDICAL IMPLANTABLE LEAD AS WELL AS A METHOD FOR IMPLANTING THE SAME 审中-公开
标题翻译：包括医用可植入引线的设备，作为用于将其植入的方法
公开(公告)号：WO2009157818A1
公开(公告)日：2009-12-30
申请号：PCT/SE2008/000416
申请日：2008-06-27
申请人： ST. JUDE MEDICAL AB , DJURLING, Henrik , HILL, Rolf , STEGFELDT, Olof , BROOME,, Åsa , STRANDBERG, Hans
发明人： DJURLING, Henrik , HILL, Rolf , STEGFELDT, Olof , BROOME,, Åsa , STRANDBERG, Hans
IPC分类号： A61N1/02 , A61N1/05 , A61N1/375
CPC分类号： A61N1/05 , A61M25/0054 , A61M2025/0063 , A61N1/056 , A61N1/086 , A61N2001/0578
摘要： The invention relates to a set comprising a medical implantable lead being adapted to be attached with a distal end of the lead to an organ inside a human or animal body. The medical implantable lead is formed with an inner lumen (7) extending along essentially the entire length of the lead. The set also comprises a support core (14), which has a desirable stiffness and a suitably cross sectional dimension such that it is insertable into the lumen (7) in order to increase the stiffness of the lead along its length during its working life when being implanted into a body. The invention also relates to a method for implanting a medical implantable lead into a human or animal body.
摘要翻译：本发明涉及一种包括医用可植入引线的组合件，其适于与引线的远端附接到人或动物体内的器官。医用可植入引线形成有沿着铅的整个长度延伸的内腔（7）。该组件还包括支撑芯（14），其具有期望的刚度和适当的横截面尺寸，使得其可插入到腔（7）中，以便在其工作寿命期间增加导线沿其长度的刚度，被植入体内。本发明还涉及一种用于将医学可植入的铅植入人体或动物体内的方法。

4. 发明申请

WO2008133575A1 A MEDICAL IMPLANTABLE LEAD AND A METHOD FOR ATTACHING THE SAME 审中-公开
标题翻译：医用可植入引线及其连接方法
公开(公告)号：WO2008133575A1
公开(公告)日：2008-11-06
申请号：PCT/SE2008/000292
申请日：2008-04-25
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof
发明人： HILL, Rolf , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： The invention relates to a medical implantable lead of the type being adapted to be implanted into a human or animal body and attached with a distal end to an organ inside the body, comprising a helix (1 ) of a helical wire in the distal end which is adapted to be screwed into the organ. In addition to the first helix, the lead also comprises a second helix (2) of a helical wire, the second helix having the same diameter, the same pitch and being intertwined with the helical wire of the first helix and which, upon rotation of the first helix, will be rotated and screwed into the tissue. The first helix is electrically non-conductive whereas the second helix is electrically conductive. The invention also relates to a method for attaching a medical implantable lead to an organ inside a human or animal body.
摘要翻译：本发明涉及一种适于被植入到人或动物体内并且具有远端附接到身体内的器官的医用可植入引线，其包括在远端的螺旋线的螺旋（1），适于拧入器官。除了第一螺旋之外，引线还包括螺旋线的第二螺旋（2），第二螺旋具有相同的直径，相同的间距并且与第一螺旋的螺旋线相互缠绕，并且在旋转时第一个螺旋，将旋转并拧入组织。第一螺旋是非导电的，而第二螺旋是导电的。本发明还涉及将医用可植入引线附接到人或动物体内的器官的方法。

5. 发明申请

WO2009002239A1 MEDICAL IMPLANTABLE LEAD AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：医用可植入式铅及其制造方法
公开(公告)号：WO2009002239A1
公开(公告)日：2008-12-31
申请号：PCT/SE2007/000634
申请日：2007-06-28
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof
发明人： HILL, Rolf , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , Y10T29/4921
摘要： The invention relates to a medical implantable lead for monitoring and/or controlling of an organ inside a human or animal body, comprising two electrical conductors (6, 9), each connected to a respective electrode for re¬ ceiving or transmitting of electrical signals from or to the organ, and a tubular header (14) in a distal end of the lead. One electrode (3) is positioned in the outermost distal end of the lead whereas the other is a ring formed electrode (16), which is mounted by means of a coupling on the outside of the lead in a proximal end of the header. According to the invention the coupling (15) and the header (14) is integrated into one unitary piece of an electrically insulating material and the coupling is formed with a quick fixating connection (17, 19) in the proximal end of the header by means of which the ring electrode (16) is mounted to the header. The invention also relates to a method for manufac- turing of a medical implantable lead.
摘要翻译：本发明涉及一种用于监测和/或控制人或动物体内器官的医用可植入引线，包括两个电导体（6,9），每个电导体连接到相应的电极，用于将电信号从或器官，以及在引线的远端中的管状头部（14）。一个电极（3）位于引线的最外远端，而另一个是环形电极（16），其通过联接器安装在引线的近端处的引线外侧。根据本发明，联接器（15）和集管（14）被整合成电绝缘材料的一个整体件，并且联接器通过装置在集管的近端形成有快速固定连接件（17,19）其中环形电极（16）安装到头部。本发明还涉及一种用于制造医用可植入引线的方法。

6. 发明申请

WO2008153451A1 MEDICAL IMPLANTABLE LEAD AND METHOD FOR MOUNTING THE SAME 审中-公开
标题翻译：医用可植入引线及其安装方法
公开(公告)号：WO2008153451A1
公开(公告)日：2008-12-18
申请号：PCT/SE2007/000582
申请日：2007-06-13
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof
发明人： HILL, Rolf , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/058
摘要： The invention relates to a medical implantable lead for monitoring and/or controlling of an organ inside a human or animal body. The lead comprising a helix (3) in a distal end which is rotatable by means of an inner wire coil (5), which is disposed inside of and along essentially the hole length of the lead and which is rotatably arranged in relation to an outer sleeve, such that the helix is attachable to the organ by being screwed into the tissue inside the body. The lead is provided with a connector (2) in a proximal end which is connectible to an electronic device for monitoring or controlling the function of the organ, the connector comprising a connector pin (4), which is in engagement with the wire coil and which is rotatably journalled inside a connector housing (7). During mounting of the medical implantable lead to the organ, the inner wire coil is rotatable by rotating the connector pin in relation to the connector housing by means of a suitable tool. According to the invention, the connector (2) is provided with a friction brake (16, 17) between the connector pin (4) and the connector housing (7). The invention also relates to a method for mounting a medical implantable lead to an organ inside a human or animal body.
摘要翻译：本发明涉及用于监测和/或控制人或动物体内的器官的医用可植入引线。所述引线包括远端的螺旋（3），所述螺旋（3）可通过内部线圈（5）旋转，所述螺旋线设置在所述引线的内部并且基本上位于所述引线的孔长度的内部，并且可相对于外部使得螺旋通过拧入到身体内的组织中而附着到器官上。引线设置有可连接到电子设备的近端的连接器（2），用于监视或控制器官的功能，该连接器包括与线圈接合的连接器销（4）和其可旋转地安装在连接器壳体（7）内。在将医用可植入引线安装到器官期间，通过借助于合适的工具使连接器销相对于连接器壳体转动，内部线圈可旋转。根据本发明，连接器（2）在连接器销（4）和连接器壳体（7）之间设置有摩擦制动器（16,17）。本发明还涉及将医用可植入引线安装在人体或动物体内的器官的方法。

7. 发明申请

WO2009082283A1 IMPLANTABLE MEDICAL LEAD 审中-公开
标题翻译：可植入医疗领域
公开(公告)号：WO2009082283A1
公开(公告)日：2009-07-02
申请号：PCT/SE2007/001154
申请日：2007-12-21
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof
发明人： HILL, Rolf , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , Y10T29/49002
摘要： The invention relates to an implantable medical lead (1) comprising a header assembly (100) having an inner header channel (130) and a radial aperture (140). An inner lead assembly (200) comprises a helical active fixation element (210) connected to an inner conductor (230). The inner lead assembly (200) is coaxially housed within the header channel (130). A post (250) is inserted into the radial aperture (140) after insertion of the inner lead assembly (200) into the channel (130). The post (250) projects radially inwardly into the header channel (130) to become interposed between adjacent turns of the helical fixation element (210). At this position the post (250) is able to transform a rotation of the helical fixation element (210) to a longitudinal movement of the fixation element (210).
摘要翻译：本发明涉及一种植入式医疗引线（1），其包括具有内部通道（130）和径向孔（140）的头部组件（100）。内引线组件（200）包括连接到内导体（230）的螺旋主动固定元件（210）。内引线组件（200）同轴地容纳在集管通道（130）内。在将内引线组件（200）插入通道（130）之后，将柱（250）插入到径向孔（140）中。柱（250）径向向内突出到集管通道（130）中以插入在螺旋固定元件（210）的相邻匝之间。在该位置，柱（250）能够将螺旋固定元件（210）的旋转变换为固定元件（210）的纵向运动。

8. 发明申请

WO2008140364A1 MEDICAL IMPLANTABLE LEAD WITH FLEXIBLE SEGMENTED SLEEVE 审中-公开
标题翻译：医用可伸缩导线，带有柔软的SEGMENTED SLEEVE
公开(公告)号：WO2008140364A1
公开(公告)日：2008-11-20
申请号：PCT/SE2007/000470
申请日：2007-05-15
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof , BARLOV, Armin
发明人： HILL, Rolf , STEGFELDT, Olof , BARLOV, Armin
IPC分类号： A61N1/05 , A61N1/02
CPC分类号： A61N1/057 , A61N1/0573
摘要： The invention relates to a medical implantable lead, which is adapted to be attached with a distal end (2) to tissue inside a human or animal body and which comprises a flexible sleeve (6) in the distal end which protrudes a distance in an axial direction from the rest of the lead. When in a desired position, a force acting in an axial direction on the flexible sleeve will bring the sleeve to be compressed in the axial direction such that the surface area of the distal end will be enlarged. According to the invention, the flexible sleeve (6) is formed with axial slots (8) from an unbroken ring segment (7) in an outermost distal edge of the sleeve and a distance in the proximal direction such that flexible segments (9) are formed in the sleeve, wherein a force acting in an axial direction on the flexible sleeve will bring the sleeve to be compressed in the axial direction by folding outwards of the flexible segments.
摘要翻译：本发明涉及一种医用可植入引线，其适于与远端（2）连接到人或动物体内的组织，并且其包括远端中的柔性套筒（6），所述柔性套筒（6）沿轴向突出一段距离方向从其余的铅。当处于所需位置时，沿着轴向方向作用在柔性套筒上的力将使套筒沿轴向方向被压缩，使得远端的表面积将被扩大。根据本发明，柔性套筒（6）在套筒的最外侧远侧边缘处形成有来自未断裂的环形部分（7）的轴向狭槽（8），并且在近端方向上具有距离，使得柔性部分（9）为形成在套筒中，其中沿着轴向方向作用在柔性套筒上的力将通过向外折叠柔性段使套筒沿轴向被压缩。

9. 发明申请

WO2009070074A1 ACTIVE FIXATION ELEMENT 审中-公开
标题翻译：主动固定元件
公开(公告)号：WO2009070074A1
公开(公告)日：2009-06-04
申请号：PCT/SE2007/050925
申请日：2007-11-29
申请人： ST. JUDE MEDICAL AB , JARL, Per, E. , HILL, Rolf , STEGFELDT, Olof
发明人： JARL, Per, E. , HILL, Rolf , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61N1/0573
摘要： The invention relates to a helical fixation element (100; 200; 300; 400; 500) of an implantable medical lead (10). The fixation element (100; 200; 300; 400; 500) comprises at least one blood drainage channel (100; 210; 310; 410; 510, 515) running along at least a tissue-penetrating portion of the helix windings (120; 220; 320; 420; 520) of the fixation element (100; 200; 300; 500; 500). The channel (100; 2100; 310; 410; 510, 510) guides, during penetration and anchoring of the fixation element (100; 200; 300; 400; 500) and the lead (1) in a tissue (55), blood leaking from the tissue (55) away from the vicinity of the fixation element (100; 200; 300; 400; 500), thereby reducing the size of a fibrin clot formed around the fixation element (100; 200; 300; 400; 500). The capture threshold for stimulating the tissue (55) is therefore reduced.
摘要翻译：本发明涉及可植入医疗引线（10）的螺旋固定元件（100; 200; 300; 400; 500）。所述固定元件（100; 200; 300; 400; 500）包括沿着所述螺旋绕组（120; 200; 300; 400; 500）的至少一个组织穿透部分延伸的至少一个排血通道（100; 210; 310; 220; 320; 420; 520）的固定元件（100; 200; 300; 500; 500）。在固定元件（100; 200; 300; 400; 500）和导线（1）在组织（55）中的穿透和锚定过程中，通道（100; 2100; 310; 410; 510,510）引导血液从所述组织（55）远离所述固定元件（100; 200; 300; 400; 500）的附近泄漏，由此减小在所述固定元件（100; 200; 300; 400; 500）周围形成的纤维蛋白凝块的尺寸）。因此减少了用于刺激组织（55）的捕获阈值。

10. 发明申请

WO2009002240A1 MEDICAL IMPLANTABLE LEAD AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：医用可植入式铅及其制造方法
公开(公告)号：WO2009002240A1
公开(公告)日：2008-12-31
申请号：PCT/SE2007/001153
申请日：2007-12-21
申请人： ST. JUDE MEDICAL AB , HILL, Rolf , STEGFELDT, Olof
发明人： HILL, Rolf , STEGFELDT, Olof
IPC分类号： A61N1/05
CPC分类号： A61N1/0573 , Y10T29/4921
摘要： The invention relates to a medical implantable lead for monitoring and/or controlling of an organ inside a human or animal body, comprising two electrical conductors (6, 9), each connected to a respective electrode for re¬ ceiving or transmitting of electrical signals from or to the organ, and a tubular header (14) in a distal end of the lead. One electrode (3) is positioned in the outermost distal end of the lead whereas the other is a ring formed electrode (16), which is mounted by means of a coupling on the outside of the header. According to the invention the coupling and the header (14) is integrated into one unitary piece of an electrically insulating material having a coupling por¬ tion (15, 25) and the coupling portion is adapted for quick fixating connection of the ring electrode to the header. The invention also relates to a method for manufacturing of a medical implantable lead.
摘要翻译：本发明涉及一种用于监测和/或控制人或动物体内器官的医用可植入引线，包括两个电导体（6,9），每个电导体连接到相应的电极，用于将电信号从或器官，以及在引线的远端中的管状头部（14）。一个电极（3）定位在引线的最外面的远端，而另一个是环形电极（16），其通过联接器安装在集管的外部。根据本发明，联接器和集管（14）被集成为具有联接部分（15,25）的电绝缘材料的一个整体件，并且联接部分适于将环形电极的连接快速固定到头。本发明还涉及医用可植入引线的制造方法。

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