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    • 1. 发明申请
    • PYRIDAZINE DERIVATIVES
    • 吡啶衍生物
    • WO2008049585A1
    • 2008-05-02
    • PCT/EP2007/009189
    • 2007-10-23
    • SYNGENTA PARTICIPATIONS AGTRAH, StephanLAMBERTH, ClemensWENDEBORN, Sebastian
    • TRAH, StephanLAMBERTH, ClemensWENDEBORN, Sebastian
    • C07D237/08C07D237/12C07D237/14C07D237/18C07D237/04C07D405/04C07D409/04C07D401/04C07D403/04C07D413/04C07D417/04C07D401/12C07D409/12C07D307/60
    • C07D237/14A01N43/58C07D237/08C07D237/12C07D307/60C07D307/79C07D401/04C07D401/12C07D403/04C07D405/04C07D405/12C07D407/04C07D409/04C07D409/12C07D413/04C07D417/04
    • The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R 1 is hydrogen, C 1 -C 6 alkyl, C 1 -C 8 haloalkyl or C 3 -C 6 cycloalkyl; R 2 is cycloalkyl, cycloalkylalkyl, halocycloalkyl, cycloalkoxy, halocycloalkoxy, cycloalkylalkoxy, halocycloalkylalkoxy, alkoxyalkyl, cycloalkoxyalkoxyalkyl, haloalkoxyalkyl, trialkylsilyl, alkylthioalkyl, haloalkylthioalkyl, cycloalkylthio, halocycloalkylthio, cycloalkylalkylthio, halocycloalkylalkylthio, alkylsulfinylalkyl, alkylsulfonylalkyl, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, optionally substituted arylsulfonyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted arylthio, optionally substituted heteroarylthio; or R 2 together with an adjacent carbon atom forms an optionally substituted fused ring; R 3 is an optionally substituted aryl; R 4 is hydrogen, halogen, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 8 alkoxy, C 1 -C 6 haloalkoxy, hydroxy or cyano; and n is a whole number from 1 to 4; or an agrochemically usable salt form thereof.
    • 本发明涉及式(I)的新颖哒嗪衍生物作为具有杀微生物活性,特别是杀真菌活性的活性成分:其中R 1是氢,C 1 -C C 1 -C 6烷基,C 1 -C 8卤代烷基或C 3 -C 6烷基, 环烷基; R 2是环烷基,环烷基烷基,卤代环烷基,环烷氧基,卤代环烷氧基,环烷基烷氧基,卤代环烷基烷氧基,烷氧基烷基,环烷氧基烷氧基烷基,卤代烷氧基烷基,三烷基甲硅烷基,烷硫基烷基,卤代烷硫基烷基,环烷硫基,卤代环烷基硫基,环烷基烷硫基,卤代环烷基烷硫基,烷基亚磺酰基烷基, 卤代烷基亚磺酰基,烷基磺酰基,卤代烷基磺酰基,C 2 -C 6亚烷基,C 2 -C 6 - 炔基,任选取代的 芳基磺酰基,任选取代的芳氧基,任选取代的杂芳氧基,任选取代的芳硫基,任选取代的杂芳硫基; 或R 2与相邻碳原子一起形成任选取代的稠合环; R 3是任选取代的芳基; R 4是氢,卤素,C 1 -C 6烷基,C 1 -C 6烷基,C 1 -C 6烷基,C 1 -C 6烷基,C 1 -C 6 - 卤代烷基,C 1 -C 8烷氧基,C 1 -C 6卤代烷氧基,羟基或 氰基; n为1〜4的整数; 或其农业化学上可用的盐形式。
    • 6. 发明申请
    • NOVEL PYRIDOPYRAZINE DERIVATIVES
    • 新型吡咯烷酮衍生物
    • WO2008031566A2
    • 2008-03-20
    • PCT/EP2007/007912
    • 2007-09-11
    • SYNGENTA PARTICIPATIONS AGSYNGENTA LIMITEDCROWLEY, Patrick, JelfLAMBERTH, ClemensWENDEBORN, Sebastian, VolkerTRAH, Stephan
    • CROWLEY, Patrick, JelfLAMBERTH, ClemensWENDEBORN, Sebastian, VolkerTRAH, Stephan
    • C07D471/04A01N43/90
    • The present invention relates to novel N -oxide derivatives of pyridopyrazines of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity :wherein X is N + -O" and Y is N; or X is N and Y is N + -O"; or X and Y are both N + -O"; R is for example H, halo, cyano, C 1-6 alkyl or C 1-6 alkoxy; R 1 is optionally substituted aryl or heteroaryl; R 2 is for example halo, C 1-8 alkyl, C 3-8 CycloaIkyI, aryl, or heteroaryl; R 3 and R 4 independently of each other are for example H, C 1-8 alkyl, halo(d-8)alkyl, C 2-8 alkenyl, C 2-8 alkynyl or aryl; or R 3 and R 4 together with the nitrogen atom to which they are attached form a C 3-10 alkylene chain or C 3-7 alkenylene chain optionally substituted with halo, C 1-4 alkyl, C 1-4 haloalkyl, C1-4 alkoxy; or R 3 and R 4 together with the nitrogen atom to which they are attached form for example a morpholine, thiomorpholine or thiomorpholine S-oxide ring; or R 3 and R 4 together with the nitrogen atom to which they are attached form a bicyclic annelated or fused ring; and R 7 and R 8 independently of each other are for example H, halo, cyano, C 1-4 alkyl, C 1-4 aIkoxy or halo(C 1-4 )alkyl.
    • 本发明涉及式(I)吡啶并吡嗪的新型N-氧化物衍生物作为具有杀微生物活性,特别是杀真菌活性的活性成分:其中X为N + -O,Y为N; 或X为N且Y为N + O“; 或X和Y均为N + O-O“; R为例如H,卤素,氰基,C 1-6烷基或C 1-6烷基, R 1是任选取代的芳基或杂芳基; R 2是例如卤素,C 1-8烷基,C 1-4烷基, 环烷基,芳基或杂芳基; R 3和R 4彼此独立地是例如H,C 1〜 烷基,卤代(C 1-8)烷基,C 2-8链烯基,C 2-8炔基或芳基;或R 3, R 4和R 4与它们所连接的氮原子一起形成C 3-10亚烷基链或C 3-7亚烷基, 任选被卤素取代的亚烯基链,C 1-4烷基,C 1-4卤代烷基,C 1-4烷氧基或R 3和R 3 与它们所连接的氮原子一起形成例如吗啉,硫代吗啉或硫代吗啉S-氧化物环;或R 3和R 4, SUP与它们所连接的氮原子一起形成a 双环环或稠环; R 7和R 8彼此独立地是例如H,卤素,氰基,C 1-4烷基,C 1 -C 4烷基, 1-4烷氧基或卤代(C 1-4烷基)烷基。