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    • 5. 发明申请
    • STABILIZED PREPARATIONS COMPRISING PHENOLIC COMPOUNDS AND BENZOPHENONES
    • 包含苯酚化合物和苯并噻唑的稳定化制剂
    • WO2007077258A1
    • 2007-07-12
    • PCT/EP2007/050123
    • 2007-01-05
    • SYMRISE GMBH & CO. KGLANGE, SabineSCHMAUS, GerhardVIELHABER, Gabriele
    • LANGE, SabineSCHMAUS, GerhardVIELHABER, Gabriele
    • A61K8/35A61K8/34A61Q19/02A61Q19/08A61Q5/08
    • A61K8/347A61K8/35A61K2800/52A61K2800/782A61Q5/08A61Q17/04A61Q19/02A61Q19/08
    • The present invention relates primarily to a cosmetic and/or pharmaceutical preparation comprising of consisting of one or more phenolic compounds of the formula (I) where for formula (I) it is the case that: R 1 , R 2 , R 3 , R 4 and R 5 are independently of one another hydrogen, halogen, an OH group, methyl or a linear or branched alkyl having 2, 3, 4 or 5 C atoms, with 1 , 2 or 3 different radicals from the group R 1 , R 2 , R 3 , R 4 and R 5 simultaneously representing an OH group, R 6 and R 7 are independently of one another hydrogen, methyl or a linear or branched alkyl having 2, 3, 4 or 5 C atoms, is an integer from O to 20 and R 8 is methyl or a linear or branched alkyl having 2 or 3 C atoms, a cycloalkyl having 3, 4, 5, 6 or 7 C atoms or a phenyl and one or more compounds of the formula (II) where for formula (II) it is the case that: R 9 , R 10 , R 11 and R 12 independently of one another are hydrogen, methyl, an OH group or a group -O- R and R 13 is methyl or a linear or branched alkyl having 2, 3, 4, 5, 6, 7, 8, 9 or 10 C atoms, and to uses of compounds of the formula (II) for stabilizing compounds of the formula (I), and also to methods of stabilizing compounds of the formula (I).
    • 本发明主要涉及一种化妆品和/或药物制剂,其包含一种或多种式(I)的酚类化合物,其中对于式(I),其中:R 1, R 2,R 3,R 4,R 5和R 5彼此独立地为氢,卤素,OH 基团,甲基或具有2,3,4或5个C原子的直链或支链烷基,具有1,2或3个不同基团R 1,R 2, R 3,R 4和R 5同时表示OH基团,R 6和R 5, 7个彼此独立地为氢,甲基或具有2,3,4或5个C原子的直链或支链烷基,为O至20的整数,R 8为甲基或 具有2或3个C原子的直链或支链烷基,具有3,4,5,6或7个C原子的环烷基或苯基和一种或多种式(II)化合物,其中对于式(II) R 9,R 9, R 10,R 11和R 12彼此独立地是氢,甲基,OH基团或基团-O-R和R“ 13是甲基或具有2,3,4,5,6,7,8,9或10个C原子的直链或支链烷基,以及式(II)化合物用于稳定化合物 式(I)化合物的方法,以及稳定式(I)化合物的方法。