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    • 9. 发明申请
    • ANTIMICROBIAL COMPOSITIONS
    • 抗微生物组合物
    • WO2018068825A1
    • 2018-04-19
    • PCT/EP2016/074286
    • 2016-10-11
    • SYMRISE AG
    • PESARO, ManuelHÖLSCHER, BerndJOIN, Benoit
    • A01N37/12A01N37/22A01N37/24A01N43/08A01P3/00A01P1/00
    • The present invention is the use of a compound of formula (I) or a (pharmaceutically) acceptable salt thereof, wherein (a) X denotes CH=CH or CZ1=CZ2, wherein if Z1 is H then Z2 denotes a radical selected from the group consisting of OH, NH 2 , NHMe, NMe 2 , OMe and OEt and if Z2 is H then Z1 denotes a radical selected from the group consisting of OH, NH 2 , NHMe, NMe 2 , OMe and OEt, Y denotes a radical selected from the group consisting of NH 2 , NHMe, NMe 2 , NHEt, O-(CH 2 ) n -OH, wherein n is 2 to 5 and R denotes a radical selected from the group consisting of H, OH, Me, Et, OMe, OEt, NH 2 , NHMe, NMe 2 , NHEt and NEt 2 , or (b) X denotes O, Y denotes a radical selected from the group consisting of NH 2 , NHMe, NMe 2 , NHEt, O-(CH 2 ) n -OH and OMe, wherein n is 2 to 5 and R denotes H, OH, Me, Et, OMe, OEt, NH 2 , NHMe, NMe 2 , NHEt, NEt 2 as antimicrobial agent as well as to composition comprising said agent.
    • (a)X表示CH = CH或CZ 1 = CZ 2,其中如果Z 1是H 则Z 2表示选自由OH,NH 2,NHMe,NMe 2,OMe和OEt组成的组的基团,并且如果Z 2是H,则Z 1表示选自 由OH,NH 2,NHMe,NMe 2,OMe和OEt组成的基团,Y表示选自NH 2 2 / ,NHMe,NMe 2,NHEt,O-(CH 2)n -OH,其中n为2至5且R表示 选自由H,OH,Me,Et,OMe,OEt,NH 2,NHMe,NMe 2,NHEt和NEt 2组成的组的基团。 (b)X表示O,Y表示选自NH 2,NHMe,NMe 2,NHEt,O-(CH 3) 其中n为2至5,并且R表示H,OH,Me,Et,OMe,OEt,NH 2 2 >,NHMe,NMe