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1. 发明申请

WO0194832A8 PIPE JOINT 审中-公开
标题翻译：管接头
公开(公告)号：WO0194832A8
公开(公告)日：2002-07-11
申请号：PCT/JP0104834
申请日：2001-06-08
申请人： SUMITOMO METAL IND , NAGASAKU SHIGEO , MAEDA JUN , SUMITANI KATSUTOSHI
发明人： NAGASAKU SHIGEO , MAEDA JUN , SUMITANI KATSUTOSHI
IPC分类号： F16L15/06
CPC分类号： F16L15/001 , F16L15/006
摘要： A pipe joint, comprising a shape having a stub side clearance (C) of 0.5-1.0 mm, a stub side thread angle ( theta ) of 15-60, the top and bottom faces of a thread positioned parallel with an axis, and a radius (R) at a male thread stub side corner of 1.0-1.25 mm, wherein a pin part having a tapered male screw formed in the end part outer peripheral surface of a tube is threaded with a box part having a tapered female screw threaded with the tapered male screw formed in the end part inner peripheral surface of the tube or a short tube, the taper of the incomplete thread part of the pin part being desirable to be 0.96-0.90 times the reference taper of the complete thread part.
摘要翻译：管接头，其包括具有0.5-1.0mm的短截边宽（C）的形状，短截线角度（θ）为15-60°，与轴线平行的螺纹的顶面和底面，以及在外螺纹短边侧角为1.0-1.25mm处的半径（R），其中形成在管的端部外周面中的具有锥形外螺纹的销部分带有带有锥形内螺纹的盒部件，形成在管的端部内周面或短管中的锥形外螺纹，销部分的不完全螺纹部分的锥度优选为完整螺纹部分的参考锥度的0.96-0.90倍。

2. 发明申请

WO2010032875A3 HETEROCYCLIC CARBOXAMIDE COMPOUNDS 审中-公开
标题翻译：杂环羧酰胺化合物
公开(公告)号：WO2010032875A3
公开(公告)日：2010-06-10
申请号：PCT/JP2009066840
申请日：2009-09-17
申请人： ASTELLAS PHARMA INC , TERASAWA TAKESHI , SHIGENAGA SHINJI , ITOH SHINJI , MAEDA JUN , WATANABE HIDEYUKI , KUBO SATOSHI , ISHII NOE
发明人： TERASAWA TAKESHI , SHIGENAGA SHINJI , ITOH SHINJI , MAEDA JUN , WATANABE HIDEYUKI , KUBO SATOSHI , ISHII NOE
IPC分类号： C07D213/82 , A61K31/44 , A61P9/00 , A61P19/00 , A61P27/00 , C07D239/48 , C07D241/26 , C07D401/12 , C07D409/12
CPC分类号： C07D213/82 , C07D239/48 , C07D241/26 , C07D401/12 , C07D409/12
摘要： This invention relates to novel heterocyclic carboxamide derivatives and salts thereof. More particularly, it relates to novel heterocyclic carboxamide derivatives and salts thereof which act as a ROCK inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of ROCK-related disease.
摘要翻译：本发明涉及新型杂环羧酰胺衍生物及其盐。更具体地说，本发明涉及作为ROCK抑制剂的新型杂环羧酰胺衍生物及其盐，涉及含有该杂环羧酰胺衍生物及其盐的治疗和/或预防ROCK相关疾病的方法。

3. 发明申请

WO2007026920A3 AMIDE DERIVATIVES AS ROCK INHIBITORS 审中-公开
标题翻译：酰胺衍生物作为岩石抑制剂
公开(公告)号：WO2007026920A3
公开(公告)日：2007-06-28
申请号：PCT/JP2006317412
申请日：2006-08-29
申请人： ASTELLAS PHARMA INC , SAWADA KOUZO , ZENKOH TATSUYA , TERASAWA TAKESHI , IMAMURA YOSHIMASA , FUKUDOME HIROKI , KURODA SATORU , MAEDA JUN , WATANABE JUNKO , INAMI HIROSHI , TAKESHITA NOBUAKI
发明人： SAWADA KOUZO , ZENKOH TATSUYA , TERASAWA TAKESHI , IMAMURA YOSHIMASA , FUKUDOME HIROKI , KURODA SATORU , MAEDA JUN , WATANABE JUNKO , INAMI HIROSHI , TAKESHITA NOBUAKI
IPC分类号： C07D213/40 , A61K31/4409 , A61K31/443 , A61K31/4436 , A61K31/4439 , A61K31/444 , C07D213/61 , C07D213/75 , C07D239/42 , C07D401/04 , C07D401/12 , C07D403/04 , C07D407/12 , C07D409/12 , C07D417/12
CPC分类号： C07D213/40 , C07D213/61 , C07D213/75 , C07D239/42 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D409/12 , C07D417/12
摘要： This invention relates to novel amide derivatives and salts thereof. More particularly, it relates to novel amide derivatives and salts thereof which act as a ROCK inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of ROCK-related disease. In the formula wherein A is lower alkyl, optionally substituted aryl, optionally substituted cycloalkyl or optionally substituted heterocyclic group; L 1 is -H or -NH 2 ; L 2 is CR 14 or N; L 3 is CH or N; L 4 is CR 2 or N.
摘要翻译：本发明涉及新颖的酰胺衍生物及其盐。更具体地说，本发明涉及作为ROCK抑制剂的新型酰胺衍生物及其盐，涉及含有该酰胺衍生物及其盐的治疗和/或预防ROCK相关疾病的方法。在其中A是低级烷基，任选取代的芳基，任选取代的环烷基或任选取代的杂环基团的式中： L 1是-H或-NH 2; L 2是CR 14或N; L 3是CH或N; L 4是CR 2 N或N.

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