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1. 发明申请

WO2010014792A3 METHOD AND DEVICE FOR INCREMENTAL WAVELENGTH VARIATION TO ANALYZE TISSUE 审中-公开
标题翻译：用于分析波长变化的分析方法和装置
公开(公告)号：WO2010014792A3
公开(公告)日：2010-04-08
申请号：PCT/US2009052220
申请日：2009-07-30
申请人： STERLING LC , JACOBSEN STEPHEN C , SMITH FRASER , MARCEAU DAVID
发明人： JACOBSEN STEPHEN C , SMITH FRASER , MARCEAU DAVID
IPC分类号： G01N21/47 , G01N21/35 , G01N33/483
CPC分类号： A61B1/06 , A61B1/00188 , A61B1/05 , A61B1/051 , A61B1/0638 , A61B1/0676 , A61B1/0684 , G01N21/255
摘要： A method of imaging a target using a miniaturized imaging device is disclosed comprising providing a miniaturized imaging device having a stationary lens system and an imaging array, wherein the distance from a distal end of the stationary lens system to the imaging array is fixed. The miniaturized imaging device is advanced near the desired target and a distance from a distal end of the stationary lens system to the desired target is determined. A desired wavelength of light is calculated based on the determined distance from the distal end of the stationary lens system to the desired target and the desired wavelength of light is propagated onto the target.
摘要翻译：公开了一种使用小型化成像装置对靶进行成像的方法，其包括提供具有固定透镜系统和成像阵列的小型化成像装置，其中固定透镜系统的远端与成像阵列的距离是固定的。小型化成像装置在期望的目标附近进行，并且确定从静止透镜系统的远端到期望目标的距离。基于从固定透镜系统的远端到期望的目标的确定的距离来计算期望的光波长，并且期望的光波长被传播到目标上。

2. 发明申请

WO2010053916A3 METHOD AND DEVICE FOR WAVELENGTH SHIFTED IMAGING 审中-公开
标题翻译：用于波长变换成像的方法和装置
公开(公告)号：WO2010053916A3
公开(公告)日：2010-08-26
申请号：PCT/US2009063116
申请日：2009-11-03
申请人： STERLING LC , JACOBSEN STEPHEN C , MARCEAU DAVID
发明人： JACOBSEN STEPHEN C , MARCEAU DAVID
IPC分类号： A61B5/1473 , A61B1/012 , A61B5/027
CPC分类号： A61B5/0084 , A61B1/00096 , A61B1/05 , A61B1/0638 , A61B5/0507 , A61B5/742 , A61B2576/00 , A61M25/0138
摘要： A micro-camera catheter device is disclosed comprising at least one light source disposed on a distal end of a catheter. The light source is capable of propagating a predetermined wavelength of light with a wavelength between approximately 1000 nanometers and approximately 2000 nanometers onto a target. The device further comprises a lens system disposed on the distal end of the catheter, said lens system configured to receive light reflected from the target. The device further comprises a non-linear optical media disposed behind the lens system configured to modify the light reflected from the target. The device also comprises a silicon-based solid state imaging device disposed behind the non-linear optical media configured to receive light from the non-linear optical media.
摘要翻译：公开了一种微型照相机导管装置，其包括设置在导管的远端上的至少一个光源。光源能够将波长在约1000纳米和约2000纳米之间的预定波长的光传播到目标上。该装置还包括设置在导管的远端上的透镜系统，所述透镜系统构造成接收从目标反射的光。该装置还包括布置在透镜系统后面的非线性光学介质，该非线性光学介质配置成修改从目标反射的光。该器件还包括设置在非线性光学介质后面的硅基固态成像器件，该非线性光学介质被配置为接收来自非线性光学介质的光。

3. 发明申请

WO2009155432A3 MINIATURIZED IMAGING DEVICE MULTIPLE GRIN LENSES OPTICALLY COUPLED TO MULTIPLE SSIDS 审中-公开
标题翻译：微型成像设备多个磨光镜片光耦合到多个SSIDS
公开(公告)号：WO2009155432A3
公开(公告)日：2010-02-25
申请号：PCT/US2009047817
申请日：2009-06-18
申请人： STERLING LC , JACOBSEN STEPHEN C , WELLS DAVID , MARCEAU DAVID
发明人： JACOBSEN STEPHEN C , WELLS DAVID , MARCEAU DAVID
IPC分类号： A61B1/00 , A61B1/05
CPC分类号： A61B1/041 , A61B1/00177 , A61B1/00179 , A61B1/00181 , A61B1/00188 , A61B1/051 , A61B5/6851 , A61B2562/0233 , A61B2562/043 , A61B2562/046
摘要： A miniaturized imaging device and method of viewing small luminal cavities are described. The imaging device can be used as part of a catheter, and can include at least one solid state imaging device (SSID) including multiple imaging arrays respectively, and multiple graduated refractive index (GRIN) lenses optically coupled to the multiple imaging arrays.
摘要翻译：描述了一种小型化成像装置和观察小腔腔的方法。成像装置可以用作导管的一部分，并且可以包括分别包括多个成像阵列的至少一个固态成像装置（SSID）和与多个成像阵列光学耦合的多个刻度折射率（GRIN）透镜。

4. 发明申请

WO2009089538A3 GRIN LENS MICROSCOPE SYSTEM 审中-公开
标题翻译： GRIN LENS MICROSCOPE系统
公开(公告)号：WO2009089538A3
公开(公告)日：2009-11-19
申请号：PCT/US2009030758
申请日：2009-01-12
申请人： STERLING LC , JACOBSEN STEPHEN C , MARCEAU DAVID P
发明人： JACOBSEN STEPHEN C , MARCEAU DAVID P
IPC分类号： G02B21/00 , G02B3/00 , G02B9/00 , G02B13/00 , G02B21/02 , G02B25/00
CPC分类号： G02B21/0008 , A61B1/00188 , G02B3/0087 , G02B6/08 , G02B6/32 , G02B21/36 , G02B23/2407
摘要： A device for magnifying an object comprising an SSID (15) having at least one imaging array disposed on a distal end (16) thereof. The device further comprises a first optical element (20) disposed on the distal end (16) of the SSID (15) wherein the first optical element (20) has a distal end (21) and a proximal end (22) defining a first longitudinal length. A GRIN lens (25) is disposed on the distal end (21) of the first optical element (20) and a second optical element (30) is disposed on the distal end (21) of the GRIN lens (25) defining a second longitudinal length. The first longitudinal length and the second longitudinal length are configured such that when viewing the object at a predetermined wavelength of light, the object is magnified at a predetermined level of magnification and the focal plane of the magnified object is aligned at the proximal end (22) of the first optical element (20).
摘要翻译：一种用于放大对象的装置，包括具有设置在其远端（16）上的至少一个成像阵列的SSID（15）。该装置还包括设置在SSID（15）的远端（16）上的第一光学元件（20），其中第一光学元件（20）具有远端（21）和近端（22），其限定第一纵长。 GRIN透镜（25）设置在第一光学元件（20）的远端（21）上，并且第二光学元件（30）设置在GRIN透镜（25）的远端（21）上，限定第二光学元件纵长。第一纵向长度和第二纵向长度被构造成使得当以预定波长的光线观察物体时，物体以预定的放大倍率放大，并且放大对象的焦平面在近端（22）处对准）的第一光学元件（20）。

5. 发明申请

WO2009155441A3 TRANSPARENT ENDOSCOPE HEAD DEFINING A FOCAL LENGTH 审中-公开
标题翻译：透明内窥镜头部定义一个正确的长度
公开(公告)号：WO2009155441A3
公开(公告)日：2010-04-15
申请号：PCT/US2009047829
申请日：2009-06-18
申请人： STERLING LC , JACOBSEN STEPHEN C , SMITH FRASER
发明人： JACOBSEN STEPHEN C , SMITH FRASER
IPC分类号： A61B1/05
CPC分类号： A61B1/00188 , A61B1/0008 , A61B1/00082 , A61B1/00147 , A61B1/00177 , A61B1/015 , A61B1/05 , A61B1/051
摘要： A catheter configured for imaging objects substantially in focus is described herein. An imaging device is disposed on the distal end of the catheter. The imaging device has an effective focal plane that is located in front of the imaging device. The catheter also includes a transparent focal instrument that has an outer periphery that is positioned at the effective focal plane of the imaging device, to enable objects in contact with the outer periphery of the transparent focal instrument to be imaged substantially in focus.
摘要翻译：这里描述了配置用于基本上聚焦的成像物体的导管。成像装置设置在导管的远端。成像装置具有位于成像装置前方的有效焦平面。导管还包括透明焦点仪器，其具有位于成像装置的有效焦平面处的外周边，以使得与透明焦点仪器的外周接触的物体能够被基本聚焦成像。

6. 发明申请

WO2011041724A3 METHOD AND APPARATUS FOR VIEWING A BODY CAVITY 审中-公开
标题翻译：用于观察身体腔的方法和设备
公开(公告)号：WO2011041724A3
公开(公告)日：2011-07-28
申请号：PCT/US2010051192
申请日：2010-10-01
申请人： JACOBSEN STEPHEN C , SMITH FRASER M , MARCEAU DAVID , MARKUS DAVID
发明人： JACOBSEN STEPHEN C , SMITH FRASER M , MARCEAU DAVID , MARKUS DAVID
IPC分类号： A61B1/05 , A61B1/055
CPC分类号： A61B1/042 , A61B1/00177 , A61B1/00179 , A61B1/00183 , A61B1/05 , A61B1/051
摘要： A method and apparatus to generate a planar representation of a longitudinally extending 360 degree continuous view within a body cavity of a patient is disclosed comprising advancing a portion of an imaging device into the body cavity of the patient, the imaging device having an image capture mechanism disposed on a distal end thereof configured to capture at least a 360 degree view of the inside of the body cavity. Further comprising withdrawing the imaging device at a controlled rate from the patient while simultaneously coordinating and generating 360 degree view image data from the imaging device and transmitting the image data from the imaging device to an image processor. The method further comprising processing the image data to produce a planar longitudinally continuous 360 degree view of the body cavity.
摘要翻译：公开了一种生成患者体腔内的纵向延伸的360度连续视图的平面表示的方法和装置，包括将成像装置的一部分推进到患者的体腔中，该成像装置具有图像捕获机构设置在其远端上，其被配置为捕获体腔内部的至少360度视图。进一步包括以受控的速率从患者取出成像装置，同时协调和生成来自成像装置的360度视图图像数据并将图像数据从成像装置传输到图像处理器。该方法还包括处理图像数据以产生体腔的平面纵向连续的360度视图。

7. 发明申请

WO2009140604A3 METHOD AND APPARATUS FOR IMAGING WITHIN A LIVING BODY 审中-公开
标题翻译：用于在生活体内成像的方法和装置
公开(公告)号：WO2009140604A3
公开(公告)日：2010-02-25
申请号：PCT/US2009044159
申请日：2009-05-15
申请人： STERLING LC , JACOBSEN STEPHEN C , WELLS DAVID H
发明人： JACOBSEN STEPHEN C , WELLS DAVID H
IPC分类号： A61B1/00 , A61B1/04 , A61B1/05
CPC分类号： A61B1/05 , A61B1/00188 , A61B1/051 , A61B5/6851 , A61M25/0147 , A61M25/0152 , A61M25/0158 , A61M2025/09183
摘要： A method and apparatus for imaging within a living body is described. The method includes directing a micro-guidewire along a primary path of the living body, the micro-guidewire having an imaging device including a SSID with an imaging array and a GRIN lens optically coupled to the imaging array. A secondary path can be identified, laterally branching from the primary path, the secondary path being of much smaller dimensions than the primary path. The distal end of the micro-guidewire can be turned and advanced into the secondary path by applied pressure at a proximal end of the micro- guidewire.
摘要翻译：描述了一种用于在活体内成像的方法和装置。该方法包括沿着生物体的主路径引导微导丝，该微导丝具有包括具有成像阵列的SSID和与成像阵列光耦合的GRIN透镜的成像装置。可以识别次要路径，从主路径横向分支，次要路径的尺寸比主路径小得多。微导丝的远端可以通过在微导丝的近端处施加的压力而转动并进入次级路径。

8. 发明申请

WO2007070534A2 ULTRA-HIGH DENSITY CONNECTOR 审中-公开
标题翻译：超高密度连接器
公开(公告)号：WO2007070534A2
公开(公告)日：2007-06-21
申请号：PCT/US2006047434
申请日：2006-12-12
申请人： SARCOS INVEST LC , JACOBSEN STEPHEN C , MARCEAU DAVID P , ZURN SHAYNE
发明人： JACOBSEN STEPHEN C , MARCEAU DAVID P , ZURN SHAYNE
IPC分类号： H01R13/648
CPC分类号： H01R13/22 , H01R13/005 , H01R13/025 , H01R13/26
摘要： Techniques for ultra-high density connection are disclosed. In one embodiment, an ultra-high density connector (10) includes a bundle of substantially parallel elongate cylindrical elements (12), where each cylindrical element is substantially in contact with at least one adjacent cylindrical element. Ends (14) of the elongate cylindrical elements are disposed differentially with respect to each other to define a three-dimensional interdigitating mating surface (16). At least one of the elongate cylindrical elements has an electrically conductive contact (18) positioned to tangentially engage a corresponding electrical contact of a mating connector.
摘要翻译：公开了用于超高密度连接的技术。在一个实施例中，超高密度连接器（10）包括一束基本平行的细长圆柱形元件（12），其中每个圆柱形元件基本上与至少一个相邻的圆柱形元件接触。细长圆柱形元件的端部（14）相对于彼此差异地设置以限定三维交错配合表面（16）。细长圆柱形元件中的至少一个具有导电接触件（18），其被定位成切向地接合配合连接器的相应电接触件。

9. 发明申请

WO2008137953A8 METHOD FOR MANUFACTURING A COMPLEX STRUCTURE 审中-公开
标题翻译：制造复杂结构的方法
公开(公告)号：WO2008137953A8
公开(公告)日：2008-12-24
申请号：PCT/US2008062945
申请日：2008-05-07
申请人： RAYTHEON SARCOS LLC , JACOBSEN STEPHEN C , MARCEAU DAVID
发明人： JACOBSEN STEPHEN C , MARCEAU DAVID
IPC分类号： A61M25/09 , A61B1/005 , B25J18/00
CPC分类号： A61M25/09 , A61M2025/09108 , Y10T29/49002 , Y10T29/49826 , Y10T428/24033
摘要： A method for manufacturing a complex structure from a two-dimensional layout, the method comprising: (a) obtaining a support plate (40) having a pre-determined, patterned recess (48) formed in a surface thereof; (b) depositing a first series of individual flexible interconnects (70) into the recess, the flexible interconnects being aligned parallel to one another in a common plane and supported by the support plate; (c) adhering, with adhering means, at least one rigid member (102) to each of the flexible interconnects of the first series; (d) adhering, with adhering means, a second series of individual flexible interconnects (132) to the rigid members to form a plurality of stations, wherein each of the second series of flexible interconnects is adhered to two rigid members of adjacent flexible interconnects of the first series, the flexible interconnects of the second series being formed perpendicular to the flexible interconnects of the first series; (e) curing the adhering means to form an assembled, layered structure; (f) removing the layered structure from the support plate; and (g) folding, systematically, the layered structure on itself and causing at least some of the stations to be supported about a central spine (160) in a segmented manner.
摘要翻译：一种从二维布局制造复杂结构的方法，所述方法包括：（a）获得在其表面形成有预定的图案化凹部（48）的支撑板（40）; （b）将第一系列单独的柔性互连件（70）沉积到所述凹部中，所述柔性互连件在公共平面中彼此平行对齐并由所述支撑板支撑; （c）用粘合装置将至少一个刚性构件（102）粘附到第一系列的每个柔性互连件上; （d）以粘合方式将第二系列单独的柔性互连件（132）粘附到所述刚性构件以形成多个工位，其中所述第二系列柔性互连件中的每一个粘附到所述第二组柔性互连件的两个刚性构件第一系列中，第二系列的柔性互连件垂直于第一系列的柔性互连件形成; （e）固化所述粘合装置以形成组装的层状结构; （f）从支撑板上移除层状结构; 并且（g）系统地折叠本身上的分层结构，并且使得至少一些站以分段方式被支撑在中心脊（160）周围。

10. 发明申请

WO2011041730A3 LIGHT DIFFUSION APPARATUS 审中-公开
标题翻译：光扩散装置
公开(公告)号：WO2011041730A3
公开(公告)日：2011-07-28
申请号：PCT/US2010051200
申请日：2010-10-01
申请人： JACOBSEN STEPHEN C , MARCEAU DAVID
发明人： JACOBSEN STEPHEN C , MARCEAU DAVID
IPC分类号： A61B1/06 , A61B1/05
CPC分类号： G02F1/133606 , A61B1/05 , A61B1/0676 , G02B5/0242 , G02B5/0247 , G02F1/133504 , G02F2001/133607 , H04N5/2251 , H04N5/2256
摘要： A light diffusing composition that optimizes image clarity from a SSID comprising a translucent matrix further comprising a plurality of hollow micro-particles. The plurality of hollow micro-particles are dispersed throughout the translucent matrix and a fluid is disposed within the hollow micro-particle. A refractive index of the fluid within the hollow micro-particle is different than a refractive index of the translucent matrix.
摘要翻译：一种光漫射组合物，其优化来自包含半透明基质的SSID的图像清晰度，所述半透明基质进一步包含多个中空微粒。多个中空微粒分散在整个半透明基质中，并且流体置于中空微粒内。中空微颗粒内的流体的折射率不同于半透明基质的折射率。

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