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1. 发明申请

WO2011011430A2 METHOD AND APPARATUS FOR PERFORMING CYTOMETRY 审中-公开
标题翻译：用于进行细胞测量的方法和设备
公开(公告)号：WO2011011430A2
公开(公告)日：2011-01-27
申请号：PCT/US2010/042629
申请日：2010-07-20
申请人： SONY CORPORATION , SONY CORPORATION OF AMERICA , SHINODA, Masataka , DURACK, Gary
发明人： SHINODA, Masataka , DURACK, Gary
IPC分类号： C12Q1/02 , G01N33/483 , C12M1/34
CPC分类号： G01N15/1484 , G01N2015/1006 , G01N2015/149
摘要： Embodiments of the present disclosure generally include a method and apparatus for performing cytometry. Specifically, embodiments of the invention comprise apparatus for providing a sample fluid to a cytometry system comprising a cytometry chip and a holder. The cytometry chip is for channeling a sample fluid from a sample fluid port to an output channel. The holder is configured to retain the cytometry chip within the holder. The holder comprises an interface between the cytometry chip and at least one of a source of the sample fluid, a source of a sheath fluid or a source of electric charge. Embodiments of a method comprise using the apparatus to provide a sample fluid to a cytometry system.
摘要翻译：本公开的实施例一般包括用于执行细胞计数的方法和装置。具体而言，本发明的实施方式包括用于将样品流体提供至包含细胞计数芯片和保持器的细胞计量系统的装置。流式细胞仪芯片用于将来自样品流体端口的样品流体引导至输出通道。保持器被构造成将细胞术芯片保持在保持器内。保持器包括细胞计量芯片与样品流体源，鞘液源或电荷源中的至少一个之间的界面。方法的实施方案包括使用该装置将样品流体提供给细胞计量系统。

2. 发明申请

WO2019013064A1 INFORMATION PROCESSING APPARATUS, INFORMATION PROCESSING METHOD, PROGRAM, AND OBSERVATION SYSTEM 审中-公开
公开(公告)号：WO2019013064A1
公开(公告)日：2019-01-17
申请号：PCT/JP2018/025333
申请日：2018-07-04
申请人： SONY CORPORATION
发明人： SHINODA, Masataka , OHASHI, Takeshi
IPC分类号： G06K9/00 , C12M1/34 , G06T7/00
摘要： There is provided an information processing apparatus, including: an image obtaining unit configured to obtain a plurality of images of a fertile ovum captured in time series; a recognizing unit including a probability image generating unit configured to generate, for each image of the fertile ovum, a probability image, wherein each position in the probability image represents the probability that at least part of the fertile ovum is present at the corresponding position in the image of the fertile ovum; and a feature amount calculating unit configured to calculate time-series transformation of the fertile ovum from the probability images over the time series, and calculate a feature amount of the fertile ovum based on the transformation.

3. 发明申请

WO2018179769A1 EMBRYONIC DEVELOPMENT ANALYSIS SYSTEM, EMBRYONIC DEVELOPMENT IMAGE ANALYSIS METHOD, NON-TRABSITORY COMPUTER READABLE MEDIUM, AND EMBRYONIC DEVELOPMENT ANALYSIS IMAGE PROCESSING DEVICE 审中-公开
公开(公告)号：WO2018179769A1
公开(公告)日：2018-10-04
申请号：PCT/JP2018/002469
申请日：2018-01-26
申请人： SONY CORPORATION
发明人： SHINODA, Masataka , OHASHI, Takeshi , ONUMA, Tomoya
IPC分类号： G06K9/00
摘要： There is provided an embryonic development analysis system, including: processing circuitry configured to: recognize a shape of one or more cells represented in one or more of a plurality of embryonic development images captured in a time series; calculate a time-series change of the shape of the one or more cells based on the recognized shape of the one or more cells in the one or more of the plurality of embryonic development images; and calculate a first feature amount based on the calculated time-series change of the shape.

4. 发明申请

WO2017056362A1 METHOD FOR ANALYZING CELL, CHIP FOR CELL ANALYSIS, REAGENT FOR CELL ANALYSIS, KIT FOR CELL ANALYSIS, AND APPARATUS FOR CELL ANALYSIS 审中-公开
标题翻译：细胞分析方法，细胞分析芯片，细胞分析试剂，细胞分析试剂盒，细胞分析仪
公开(公告)号：WO2017056362A1
公开(公告)日：2017-04-06
申请号：PCT/JP2016/003608
申请日：2016-08-04
申请人： SONY CORPORATION
发明人： MATSUMOTO, Masahiro , SHINODA, Masataka , WATANABE, Yuuki
IPC分类号： G01N33/569
CPC分类号： G01N33/569
摘要： According to some aspects, a method for analyzing a cell is provided. The method includes trapping the cell by binding a first molecule to the cell. The method further includes binding a second molecule to the cell. The second molecule includes a binding portion capable of specific binding to a cell-surface molecule of the cell. The second molecule further includes an identifying portion, a labeling portion coupled to the identifying portion, and a stimulus-degradable linker between the binding portion and the identification portion. The method further includes detaching the identifying portion from the binding portion by stimulating the stimulus-degradable linker where the detached identifying portion is coupled to the labeling portion. The method further includes binding the detached identifying portion through specific binding to an identifying portion recognizing molecule and detecting the labeling portion.
摘要翻译：根据一些方面，提供了一种用于分析单元的方法。该方法包括通过将第一分子结合到细胞来捕获细胞。该方法还包括将第二分子与细胞结合。第二分子包括能够特异性结合细胞的细胞表面分子的结合部分。第二分子还包括识别部分，耦合到识别部分的标记部分和结合部分和识别部分之间的刺激可降解接头。该方法还包括通过刺激可分解的识别部分与标记部分耦合的刺激可降解的接头来将其识别部分从结合部分分离。该方法还包括通过特异性结合将分离的识别部分结合到识别部分识别分子并检测标记部分。

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