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    • 4. 发明申请
    • COMPOSITION, APPARATUS, KIT AND METHOD AND USES THEREOF
    • 组合物,装置,套件及其方法及其用途
    • WO2013076450A1
    • 2013-05-30
    • PCT/GB2012/000866
    • 2012-11-26
    • SMITH & NEPHEW PLC
    • HARTWELL, Edward YerburyFRYER, Christopher JohnCOLLINSON, Sarah JennyPHILLIPS, Marcus Damian
    • A61F13/02A61L24/04A61M1/00
    • C09J183/00A61F13/00063A61F13/00068A61F13/0216A61F17/00A61L15/225A61L15/42A61L15/585A61M1/0088A61M5/19C09J201/02C08L83/04
    • A curable composition for use in wound care comprising, apportioned between at least one Part A and at least one Part B: one or more alkenyl-group containing polymers (i) having at least one alkenyl group or moiety per molecule, one or more SiH-containing polymers (ii) having at least one Si-H unit per molecule; and a catalyst (iii) for curing by addition of alkenyl-contatning polymer (i) to SiH-contain/ng polymer (ii), Part A and Part B independently having viscosity at 23°C in the range 5 - 300 Pa.s, preferably 10 - 100 Pa s, at a shearing rate of 10 s -1 , and when combined in one Part having cure time at 23° C in the range from 0.5 min to 25 min, wherein when dispensed into a location about a wound dressing, said wound dressing overlying a wound site and skin thereabout, said dispensing being so as to intimately contact and overlie an edge of said dressing and skin about said edge, the composition cures in contact with said edge and skin at 32° C to an elastomer exhibiting zero or low tack at a time in the range from 0.5 to less than 30 minutes, apparatus for use with said composition comprising dispensing apparatus or wound dressing, a kit comprising the same, and methods of dispensing and curing the same and of using the same in sealing a wound dressing and in treating a wound site of a human in need thereof.
    • 一种用于伤口护理的可固化组合物,包括在至少一份A部分和至少一份B部分之间分配:一种或多种含烯基基团的聚合物(i)每分子具有至少一个烯基或部分,一个或多个SiH (ii)每分子具有至少一个Si-H单元; 以及通过向含SiH的/ ng聚合物(ii),部分A和部分B中加入含链烯基的聚合物(i)固化的催化剂(iii),其独立地在23℃下的粘度在5-300Pa.s ,优选10-100Pa s,剪切速率为10s-1,当在一个部分中组合时,其固化时间为23℃,范围为0.5分钟至25分钟,其中当分配到围绕伤口的位置时 敷料,所述伤口敷料覆盖伤口部位和皮肤周围,所述分配是使所述敷料和皮肤的边缘与所述边缘紧密接触和覆盖,所述组合物在32℃下与所述边缘和皮肤接触固化至 在0.5至小于30分钟的时间内呈现零或低粘性的弹性体,用于所述组合物的装置包括分配装置或伤口敷料,包含该组合物的试剂盒及其分配和固化方法以及使用 密封伤口敷料和治疗伤口部位也是一样的 有需要的人。