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1. 发明申请

WO2009145591A2 PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF 审中-公开
标题翻译：苯基哌嗪化合物，包括其的药物组合物及其用途
公开(公告)号：WO2009145591A2
公开(公告)日：2009-12-03
申请号：PCT/KR2009002881
申请日：2009-05-29
申请人： SK HOLDINGS CO LTD , KIM YONGGIL , CHO NAHMRYUNE , KIM YUNHEE , HEO JOON , DONG SEONMIN , JI MI KYUNG , CHA MAN-YOUNG , LEE KIHO
发明人： KIM YONGGIL , CHO NAHMRYUNE , KIM YUNHEE , HEO JOON , DONG SEONMIN , JI MI KYUNG , CHA MAN-YOUNG , LEE KIHO
IPC分类号： C07D241/04 , A61K31/498 , C07D241/02 , C07D403/08
CPC分类号： C07D295/088 , C07D295/096
摘要： The present invention relates to novel piperazine derivatives or pharmaceutically acceptable salts thereof, and a pharmaceutical composition for treatment and/or prevention of depression and anxiety including an effective amount of the piperazine compound.
摘要翻译：本发明涉及新颖的哌嗪衍生物或其药学上可接受的盐，以及用于治疗和/或预防抑郁和焦虑的药物组合物，包括有效量的哌嗪化合物。

2. 发明申请

WO2009145590A2 PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, AND USE THEREOF 审中-公开
标题翻译：苯基哌嗪化合物，包含其的药物组合物及其用途
公开(公告)号：WO2009145590A2
公开(公告)日：2009-12-03
申请号：PCT/KR2009002880
申请日：2009-05-29
申请人： SK HOLDINGS CO LTD , KIM YONGGIL , LEE KIHO , CHO NAHMRYUNE , YOO JIN UK , HEO JOON , RYU CHOONHO , DONG SEONMIN , CHA MAN-YOUNG , CHOI JONG GIL , KIM YUNHEE , JI MI KYUNG
发明人： KIM YONGGIL , LEE KIHO , CHO NAHMRYUNE , YOO JIN UK , HEO JOON , RYU CHOONHO , DONG SEONMIN , CHA MAN-YOUNG , CHOI JONG GIL , KIM YUNHEE , JI MI KYUNG
IPC分类号： C07D241/12 , A61K31/496 , A61P21/00 , C07D241/04
CPC分类号： C07D295/088 , C07D295/096
摘要： The present invention relates to a novel piperazine derivative or pharmaceutically acceptable salt thereof, a process for preparing the same, a pharmaceutical composition for treating central nervous system diseases comprising an effective amount of the piperazine compound and a method of treating central nervous system (CNS) disorder such as psychosis in a mammal.
摘要翻译：本发明涉及一种新的哌嗪衍生物或其药学上可接受的盐，其制备方法，用于治疗中枢神经系统疾病的药物组合物，其包含有效量的哌嗪化合物和治疗中枢神经系统（CNS）的方法，疾病如精神病在哺乳动物中。

3. 发明申请

WO2012067377A3 CAMERA MODULE AND METHOD FOR MANUFACTURING THE SAME 审中-公开
标题翻译：相机模块及其制造方法
公开(公告)号：WO2012067377A3
公开(公告)日：2012-09-20
申请号：PCT/KR2011008538
申请日：2011-11-10
申请人： LG INNOTEK CO LTD , LEE KIHO
发明人： LEE KIHO
IPC分类号： H04N5/225 , G03B3/02 , G03B17/02
CPC分类号： H04N5/2252 , G03B17/02 , H04N5/2253 , H04N5/2257 , Y10T29/49128
摘要： The present invention relates to a camera module, the camera module including: a PCB (Printed Circuit Board), an image sensor mounted on the PCB and formed with an imaging device for converting light to an electrical signal; a housing fixed a bottom end to an upper surface of the PCB, the housing being a case formed with a hole at an upper center and having a bottom-opened inner space; a lens assembly having at least one lens aligned to the lens hole by being positioned at and contacted to an upper surface of the image sensor and accommodated at an inner space of the housing; and an elastic stiffening material inserted between a lens hole periphery at an upper inner side of the housing and an upper edge of the lens assembly.
摘要翻译：本发明涉及一种照相机模块，该照相机模块包括：PCB（印刷电路板）;图像传感器，安装在PCB上并形成有用于将光转换为电信号的成像装置; 壳体，其底端固定到所述PCB的上表面，所述壳体是在上部中心处形成有孔且具有底部开口的内部空间的壳体; 透镜组件，所述透镜组件具有至少一个透镜，所述透镜通过定位在所述图像传感器的上表面并与所述上表面接触并且容纳在所述外壳的内部空间处而与所述透镜孔对准; 以及插入在壳体的上部内侧处的透镜孔周边与透镜组件的上部边缘之间的弹性加强材料。

4. 发明申请

WO2011043630A2 COMPOSITION FOR PREVENTING AND TREATING OBESITY DISEASES CONTAINING HIGHLY WATER-SOLUBLE 2-HYDROXYPROPYL-?-CYCLODEXTRIN AS ACTIVE INGREDIENT 审中-公开
标题翻译：用于预防和治疗含有高水溶性2-羟基丙酸 - β-环糊精作为活性成分的肥胖症的组合物
公开(公告)号：WO2011043630A2
公开(公告)日：2011-04-14
申请号：PCT/KR2010006912
申请日：2010-10-08
申请人： SONG HO BIOMED CO LTD , HAN GYOON-HEE , CHOI YONG SEOK , HAN SANG-BAE , LEE JONG HO , KIM HWAN MOOK , PARK SONG-KYU , LEE KIHO , KANG JONG SOON , LEE KI HOON , LEE CHANG WOO
发明人： HAN GYOON-HEE , CHOI YONG SEOK , HAN SANG-BAE , LEE JONG HO , KIM HWAN MOOK , PARK SONG-KYU , LEE KIHO , KANG JONG SOON , LEE KI HOON , LEE CHANG WOO
IPC分类号： A61K31/724 , A61P3/00 , A61P3/04
CPC分类号： A61K31/724 , A23L29/35 , A23L33/10 , A23V2002/00 , A23V2200/328 , A23V2200/332 , A23V2250/5112
摘要： The present invention relates to a composition for preventing and treating obesity containing highly water-soluble ß-cyclodextrin derivatives as an active ingredient. More specifically, the composition containing highly water-soluble ß-cyclodextrin derivatives, particularly 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD, HPBCD), inhibits the weight increase induced by a high fat diet, inhibits appetite through the decrease of food intake, reduces body fat, reduces the weight of a liver, and remarkably inhibits the rapid increase of blood glucose induced by the intake of glucose and maltose on an empty stomach, thereby enabling helpful use for preventing and treating obesity, preventing and treating various diseases induced by obesity and inhibiting the rapid increase of blood sugar after meals.
摘要翻译：本发明涉及用于预防和治疗含有高度水溶性β-环糊精衍生物作为活性成分的肥胖症的组合物。更具体地，含有高度水溶性的β-环糊精衍生物，特别是2-羟丙基-β-环糊精（HP-β-CD，HPBCD）的组合物抑制高脂肪饮食引起的体重增加，通过降低食物摄取，减少体脂肪，减轻肝脏的重量，并且显着抑制空腹时摄入葡萄糖和麦芽糖引起的血糖的快速增加，从而有助于预防和治疗肥胖症，预防和治疗各种各样的肥胖引起的疾病和饭后血糖快速增加。

5. 发明申请

WO2010064817A3 NOVEL COUMARIN-BASED COMPOUNDS, PREPARATION METHOD THEREOF, AND MULTIDRUG RESISTANCE INHIBITORY PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENTS 审中-公开
标题翻译：新型香豆素类化合物及其制备方法和含有该化合物作为活性成分的多药抗性抑制药物组合物
公开(公告)号：WO2010064817A3
公开(公告)日：2010-09-30
申请号：PCT/KR2009007077
申请日：2009-11-30
申请人： KOREA RES INST OF BIOSCIENCE , LEE KYEONG , MIN KYUNG HOON , LEE KIHO , CHOI YONGSEOK , JIN YINGLAN , XIA YAN
发明人： LEE KYEONG , MIN KYUNG HOON , LEE KIHO , CHOI YONGSEOK , JIN YINGLAN , XIA YAN
IPC分类号： C07D311/10
CPC分类号： C07D311/16
摘要： The present invention relates to novel coumarin-based compounds, to a preparation method thereof, and to multidrug resistance inhibitory pharmaceutical compositions containing same as active ingredients. The coumarin-based compounds according to the present invention exhibit inhibitory activities against the overexpression of P-glycoprotein (Pgp) which is the main cause of multidrug resistance, and increase anticancer activities when administered in combination with anticancer drugs. Therefore, the coumarin-based compounds of the present invention can be used as agents for overcoming, treating, or controlling multidrug resistance against anticancer drugs. The coumarin-based compounds of the present invention increase the effects of anticancer drugs to raise the survival rate of cancer patients. The coumarin-based compounds of the present invention reduce the dose of anticancer drugs administered in combination with the coumarin-based compounds to reduce the side effects against normal cells, and are therefore useful in anticancer treatments.
摘要翻译：本发明涉及新型香豆素类化合物，其制备方法以及含有该化合物作为活性成分的多药物抗性抑制药物组合物。本发明的香豆素类化合物对抗多药耐药的主要原因P-糖蛋白（Pgp）的过量表达具有抑制活性，并且与抗癌药物组合施用时提高抗癌活性。因此，本发明的香豆素类化合物可以用作克服，治疗或控制对抗癌药物的多重抗药性的药剂。本发明的基于香豆素的化合物增加抗癌药物的作用以提高癌症患者的存活率。本发明的基于香豆素的化合物减少了与香豆素类化合物组合给药的抗癌药物的剂量，以减少对正常细胞的副作用，因此可用于抗癌治疗。

6. 发明申请

WO2011043630A3 COMPOSITION FOR PREVENTING AND TREATING OBESITY DISEASES CONTAINING HIGHLY WATER-SOLUBLE 2-HYDROXYPROPYL-?-CYCLODEXTRIN AS ACTIVE INGREDIENT 审中-公开
公开(公告)号：WO2011043630A3
公开(公告)日：2011-10-13
申请号：PCT/KR2010006912
申请日：2010-10-08
申请人： SONG HO BIOMED CO LTD , HAN GYOON-HEE , CHOI YONG SEOK , HAN SANG-BAE , LEE JONG HO , KIM HWAN MOOK , PARK SONG-KYU , LEE KIHO , KANG JONG SOON , LEE KI HOON , LEE CHANG WOO
发明人： HAN GYOON-HEE , CHOI YONG SEOK , HAN SANG-BAE , LEE JONG HO , KIM HWAN MOOK , PARK SONG-KYU , LEE KIHO , KANG JONG SOON , LEE KI HOON , LEE CHANG WOO
IPC分类号： A61K31/724 , A61P3/00 , A61P3/04
CPC分类号： A61K31/724 , A23L29/35 , A23L33/10 , A23V2002/00 , A23V2200/328 , A23V2200/332 , A23V2250/5112
摘要： The present invention relates to a composition for preventing and treating obesity containing highly water-soluble ß-cyclodextrin derivatives as an active ingredient. More specifically, the composition containing highly water-soluble ß-cyclodextrin derivatives, particularly 2-hydroxypropyl-ß-cyclodextrin (HP-ß-CD, HPBCD), inhibits the weight increase induced by a high fat diet, inhibits appetite through the decrease of food intake, reduces body fat, reduces the weight of a liver, and remarkably inhibits the rapid increase of blood glucose induced by the intake of glucose and maltose on an empty stomach, thereby enabling helpful use for preventing and treating obesity, preventing and treating various diseases induced by obesity and inhibiting the rapid increase of blood sugar after meals.

7. 发明申请

WO2012053787A3 ARYLOXY PHENOXY ACRYLIC COMPOUND HAVING HIF-1 INHIBITION ACTIVITY, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS AN ACTIVE INGREDIENT 审中-公开
标题翻译：具有HIF-1抑制活性的芳氧基苯氧基丙烯酸化合物，其制备方法以及含有该化合物作为活性成分的药物组合物
公开(公告)号：WO2012053787A3
公开(公告)日：2012-07-26
申请号：PCT/KR2011007710
申请日：2011-10-17
申请人： KOREA RES INST OF BIOSCIENCE , UNIV DONGGUK IND ACAD COOP , LEE KYEONG , WON MI SUN , KIM HWAN MOOK , PARK SONG KYU , LEE KIHO , LEE KI HOON , LEE CHANG WOO , LEE JUNG JOON , CHUNG KYUNG SOOK , KIM BO KYUNG , JIN YINGLAN , LEE SEUNG-HEE
发明人： LEE KYEONG , WON MI SUN , KIM HWAN MOOK , PARK SONG KYU , LEE KIHO , LEE KI HOON , LEE CHANG WOO , LEE JUNG JOON , CHUNG KYUNG SOOK , KIM BO KYUNG , JIN YINGLAN , LEE SEUNG-HEE
IPC分类号： C07C235/38 , A61K31/167 , A61P35/00 , C07C231/02
CPC分类号： A61K31/5375 , A61K9/0019 , A61K9/08 , A61K9/14 , A61K9/20 , A61K9/48 , A61K31/167 , A61K31/196 , A61K31/24 , A61K31/34 , A61K31/40 , A61K31/417 , A61K31/4409 , C07C233/07 , C07C235/28 , C07C311/16 , C07C311/46 , C07C317/40 , C07C2603/74 , C07D295/088
摘要： The present invention relates to a compound having HIF-1 inhibition activity, to a method for preparing same, and to a pharmaceutical composition containing same as an active ingredient. The compound of the present invention exhibits anticancer activity by inhibiting the activity of HIF-1, which is a transcription factor that plays a significant role in cancer cell growth and metastasis, and does not indicate non-selective, cytotoxic anti-tumour activity. Accordingly, the compound or a pharmaceutically acceptable salt thereof according to the present invention inhibits HIF-1 activity, and therefore can be used as a therapeutic agent for solid tumours such as colon cancer, liver cancer, stomach cancer and breast cancer. In addition, the compound or the pharmaceutically acceptable salt thereof according to the present invention can be used as an active ingredient for a therapeutic agent for diabetic retinopathy or arthritis which may become worse when hypoxia-induced VEGF expression by HIF-1 increases.
摘要翻译：本发明涉及具有HIF-1抑制活性的化合物，其制备方法，以及含有该化合物作为有效成分的药物组合物。本发明化合物通过抑制作为在癌细胞生长和转移中起重要作用的转录因子HIF-1的活性而显示出抗癌活性，并且不表示非选择性的细胞毒性抗肿瘤活性。因此，本发明的化合物或其药学上可接受的盐可以抑制HIF-1活性，因此可以用作结肠癌，肝癌，胃癌，乳癌等实体瘤的治疗剂。另外，根据本发明的化合物或其药学上可接受的盐可以用作用于糖尿病性视网膜病或关节炎的治疗剂的活性成分，其在HIF-1引起的低氧诱导的VEGF表达增加时可能变得更差。

8. 发明申请

WO2011014009A3 NOVEL DI-SUBSTITUTED PHENOXYACETYL-BASED COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PRODUCTION METHOD FOR SAME AND PHARMACEUTICAL COMPOSITION FOR SUPPRESSING MULTIPLE DRUG RESISTANCE COMPRISING SAME AS AN ACTIVE INGREDIENT 审中-公开
标题翻译：新型二取代的基于羟基乙酸的化合物或其药学上可接受的盐，其生产方法和药物组合物，用于抑制包含作为活性成分的多种药物耐药性
公开(公告)号：WO2011014009A3
公开(公告)日：2011-04-28
申请号：PCT/KR2010004967
申请日：2010-07-28
申请人： KOREA RES INST OF BIOSCIENCE , LEE KYEONG , MIN KYUNG HOON , LEE KIHO , XIA YAN , JIN YINGLAN
发明人： LEE KYEONG , MIN KYUNG HOON , LEE KIHO , XIA YAN , JIN YINGLAN
IPC分类号： C07C235/38 , A61K31/167 , A61P35/00 , C07D217/12
CPC分类号： A61K31/167 , C07C235/40 , C07C237/42 , C07C255/60 , C07C2603/74 , C07D217/06
摘要： The present invention relates to a novel di-substituted phenoxyacetyl-based compound, a production method for the same and a pharmaceutical composition for suppressing multiple drug resistance comprising the same as an active ingredient. The novel di-substituted phenoxyacetyl-based compound of the present invention exhibits a suppressing activity on over-expression of P-glycoprotein (Pgp), which is a major cause of multiple drug resistance, and exhibits increased anticancer activity when administered conjointly with an anticancer agent such that it can be usefully employed in anticancer therapy as it can be used as a preparation for overcoming multiple drug resistance to anticancer agents, and as a therapeutic or a regulating preparation, and can enhance the effects of anticancer preparations and increase the survival rates of cancer patients, and can also lessen the side effects on normal cells since the dose(s) of the anticancer preparation(s) being used conjointly, can be reduced.
摘要翻译：本发明涉及一种新的二取代的苯氧基乙酰基类化合物，其制备方法和用于抑制多种耐药性的药物组合物，其包含其作为活性成分。本发明的新型二取代苯氧乙酰基类化合物对作为多重耐药性的主要原因的P-糖蛋白（Pgp）的过表达具有抑制活性，与抗癌剂一起施用时，其抗癌活性增加可以有效地用于抗癌治疗，因为它可以用作克服抗癌剂的多重耐药性的制剂，以及作为治疗或调节制剂，并且可以增强抗癌制剂的作用并增加存活率因为可以减少与抗癌剂一起使用的剂量，所以可以降低对正常细胞的副作用。

9. 发明申请

WO2009093872A3 NOVEL DIAMINE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR TREATING CANCERS CONTAINING SAME 审中-公开
标题翻译：新型DIAMINE化合物或其药学上可接受的盐，其制备方法和用于治疗含有其的癌症的药物组合物
公开(公告)号：WO2009093872A3
公开(公告)日：2009-11-05
申请号：PCT/KR2009000375
申请日：2009-01-23
申请人： KOREA RES INST OF BIOSCIENCE , SEOUL PHARMA CO LTD , IND ACADEMIC COOP , HAN GYOONHEE , YANG JEE SUN , NAM MIHEE , LEE CHUL HO , SONG DOONA , WON MISUN , CHUNG KYUNG-SOOK , KIM DONG-MYUNG , YOO HYANG-SOOK , KIM HWAN MOOK , PARK SONG-KYU , LEE KIHO , LEE CHANG WOO , KO WONJIN , RYOO BYUNG-HWAN , CHOI NAM-SONG , JEONG YONG-MI
发明人： HAN GYOONHEE , YANG JEE SUN , NAM MIHEE , LEE CHUL HO , SONG DOONA , WON MISUN , CHUNG KYUNG-SOOK , KIM DONG-MYUNG , YOO HYANG-SOOK , KIM HWAN MOOK , PARK SONG-KYU , LEE KIHO , LEE CHANG WOO , KO WONJIN , RYOO BYUNG-HWAN , CHOI NAM-SONG , JEONG YONG-MI
IPC分类号： C07C211/62
CPC分类号： C07C311/05 , C07C233/36 , C07C233/43 , C07C311/08
摘要： The present invention relates to a novel diamine compound or pharmaceutically acceptable salts thereof, method for preparing same, and a pharmaceutical composition for treating cancers containing same. The compound of the present invention exhibits superior effects of suppressing growth of tumor cells, and therefore can be valuable in treating cancer disease.
摘要翻译：本发明涉及新型二胺化合物或其药学上可接受的盐，其制备方法和用于治疗含有其的癌症的药物组合物。本发明的化合物表现出抑制肿瘤细胞生长的优异效果，因此在治疗癌症方面是有价值的。

10. 发明申请

WO2011081420A2 STABILIZED CAMERA MODULE 审中-公开
标题翻译：稳定相机模块
公开(公告)号：WO2011081420A2
公开(公告)日：2011-07-07
申请号：PCT/KR2010009449
申请日：2010-12-28
申请人： LG INNOTEK CO LTD , LEE KIHO
发明人： LEE KIHO
IPC分类号： H04N5/225
CPC分类号： H04N5/2252 , H04N5/2257
摘要： The present invention relates to a stabilized camera module configured to prevent instable movement of a bobbin caused by outside force, the module including a holder formed at a lateral surface with at least one slit, a bobbin movably coupled to an inside of the holder and having a protruder protruding outside of the holder by penetrating the slit, a lens assembly coupled to an inside of the bobbin and including one or more lenses receiving an optical image of an object, and one or more elastic members formed between the holder and the bobbin to prevent the bobbin from moving to one side of the holder.
摘要翻译：本发明涉及一种稳定的相机模块，其被配置为防止由外力引起的筒管不稳定的移动，所述模块包括形成在具有至少一个狭缝的侧表面的保持器，可移动地联接到所述保持器的内部的筒管，通过穿过狭缝而突出在保持器外侧的突出部，连接到线轴的内部并且包括容纳物体的光学图像的一个或多个透镜以及形成在保持器和线轴之间的一个或多个弹性部件的透镜组件，防止梭芯移动到支架的一侧。

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