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1. 发明申请

WO2008051800A2 VISUAL PROSTHESIS 审中-公开
标题翻译：视觉预告
公开(公告)号：WO2008051800A2
公开(公告)日：2008-05-02
申请号：PCT/US2007/081811
申请日：2007-10-18
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , GREENBERG, Robert, J. , MCCLURE, Kelly, H. , ROY, Arup
发明人： GREENBERG, Robert, J. , MCCLURE, Kelly, H. , ROY, Arup
IPC分类号： A61N1/36 , A61F9/00
CPC分类号： A61F9/08 , A61N1/36046 , A61N1/37276 , A61N1/3787 , G02C11/10 , H04N5/2254
摘要： A visual prosthesis apparatus and a method for limiting power consumption in a visual prosthesis apparatus. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit associated with the camera, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stop stimulating neural tissue in a subject's eye based on the stimulation patterns when an error is detected in a forward telemetry received from the video processing unit.
摘要翻译：一种视觉假体装置和用于限制视力假体装置中的功率消耗的方法。视觉假体装置包括用于捕获视频图像的相机，与相机相关联的视频处理单元，视频处理单元，被配置为将视频图像转换为刺激图案;以及视网膜刺激系统，被配置为停止刺激受试者的神经组织基于在从视频处理单元接收的前向遥测中检测到错误时的刺激模式的眼睛。

2. 发明申请

WO2006081300A1 NEURAL STIMULATION FOR INCREASED PERSISTENCE 审中-公开
标题翻译：神经刺激增加的持续时间
公开(公告)号：WO2006081300A1
公开(公告)日：2006-08-03
申请号：PCT/US2006/002659
申请日：2006-01-24
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , DOHENY EYE INSTITUTE , ROY, Arup , GREENBERG, Robert, J , HUMAYUN, Mark, S , MCCLURE, Kelly, H
发明人： ROY, Arup , GREENBERG, Robert, J , HUMAYUN, Mark, S , MCCLURE, Kelly, H
IPC分类号： A61N1/36
CPC分类号： A61N1/36046
摘要： The present invention is directed to neural stimulation and more specifically to an improved apparatus and method of neural stimulation for improved persistence of electrical neural stimulation, and specifically an apparatus and a method of improving the persistence of an image supplied to the retina, or visual cortex, through a visual prosthesis. A continuously stimulated retina, or other neural tissue, will adapt or desensitize after a time period in the range of 20 to 150 seconds. However, an interruption of the stimulation on the order of a few milliseconds will restore the retinal sensitivity without the user perceiving the interruption, or with the user barely perceiving the interruption. A typical perceptual response to a constant stimulus begins to decay immediately. A stimulus creates a percept (50) that gradually decays (52) until the precept disappears, (54). An interruption of the stimulus, (56) brings the precept back to a full response (58) and decay begins again.
摘要翻译：本发明涉及神经刺激，并且更具体地涉及用于改善电神经刺激持续性的神经刺激的改进的装置和方法，具体地说，一种改善提供给视网膜或视皮层的图像持续性的装置和方法，通过视觉假体。持续刺激的视网膜或其他神经组织将在20至150秒的时间段内适应或脱敏。然而，几毫秒级别的刺激的中断将恢复视网膜灵敏度，而不会使用户感觉到中断，或者用户几乎感觉到中断。对恒定刺激的典型感知反应立即开始衰减。刺激产生一种逐渐衰退（52）的知觉（50），直到戒律消失，（54）。刺激的中断，（56）使得戒律恢复到完全的反应（58），衰减再次开始。

3. 发明申请

WO2008153592A1 VIDEO PROCESSING UNIT FOR A VISUAL PROSTHETIC APPARATUS 审中-公开
标题翻译：视频预处理设备的视频处理单元
公开(公告)号：WO2008153592A1
公开(公告)日：2008-12-18
申请号：PCT/US2007/083944
申请日：2007-11-07
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , MCCLURE, Kelly H. , ROY, Arup , CASTRO, Richard Agustin , YADAV, Sumit , DAI, Rongqing , GREENBERG, Robert J. , CHANG, Da-Yu , WU, Xiaofan , LOFTIN, Scott , MCCORD, Susan
发明人： MCCLURE, Kelly H. , ROY, Arup , CASTRO, Richard Agustin , YADAV, Sumit , DAI, Rongqing , GREENBERG, Robert J. , CHANG, Da-Yu , WU, Xiaofan , LOFTIN, Scott , MCCORD, Susan
IPC分类号： A61N1/36
CPC分类号： A61N1/36046 , A61N1/37247 , A61N1/37258
摘要： A visual prosthesis apparatus and a method for providing artificial vision are disclosed in the present disclosure. The visual prosthesis apparatus comprises a video capture device for capturing a video image, a video processing unit associated with the video capture device, the video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured to stimulate neural tissue in a subject's eye based on the stimulation patterns, wherein the video processing unit is configured to be powered on after a first time interval upon activation of a power button, wherein the video processing unit is configured to be powered off after a second time interval upon activation of a power button.
摘要翻译：在本公开中公开了一种视觉假体装置和用于提供人造视觉的方法。视觉假体装置包括用于捕获视频图像的视频捕获装置，与视频捕捉装置相关联的视频处理单元，被配置为将视频图像转换成刺激模式的视频处理单元以及被配置为刺激神经组织的视网膜刺激系统基于刺激模式在受试者的眼中，其中视频处理单元被配置为在激活电源按钮之后在第一时间间隔之后通电，其中视频处理单元被配置为在第二时间间隔之后关闭电源激活电源按钮。

4. 发明申请

WO2008109771A2 SALIENCY-BASED APPARATUS AND METHODS FOR VISUAL PROSTHESES 审中-公开
标题翻译：基于SALIENCY的设备和视觉展示的方法
公开(公告)号：WO2008109771A2
公开(公告)日：2008-09-12
申请号：PCT/US2008/056089
申请日：2008-03-06
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , DOHENY EYE INSTITUTE , GREENBERG, Robert, J. , HORSAGER, Alan, Matthew , HUMAYUN, Mark, S. , MCCLURE, Kelly, H. , MCMAHON, Matthew, J. , MEILSTRUP, Peter , PARIKH, Neha, Jagdish , ROY, Arup , WEILAND, James, D. , ZHOU, Chunhong
发明人： GREENBERG, Robert, J. , HORSAGER, Alan, Matthew , HUMAYUN, Mark, S. , MCCLURE, Kelly, H. , MCMAHON, Matthew, J. , MEILSTRUP, Peter , PARIKH, Neha, Jagdish , ROY, Arup , WEILAND, James, D. , ZHOU, Chunhong
IPC分类号： A61N1/36
CPC分类号： A61N1/36046 , A61F9/08 , G06K9/4604 , G06K9/4628 , G06K9/605 , G09B21/008
摘要： Saliency-based apparatus and methods for visual prostheses are disclosed. A saliency-based component processes video data output by a digital signal processor before the video data are input to the retinal stimulator. In a saliency-based method, an intensity stream is extracted from an input image, feature maps based on the intensity stream are developed, plural most salient regions of the input image are detected and one of the regions is selected as a highest saliency region.
摘要翻译：公开了用于视觉假体的基于显着性的装置和方法。基于显眼的组件在将视频数据输入到视网膜刺激器之前处理由数字信号处理器输出的视频数据。在基于显着性的方法中，从输入图像中提取强度流，基于强度流形成特征图，检测输入图像的多个最显着区域，并选择其中一个区域作为最高显着区域。

5. 发明申请

WO2008011096A2 APPARATUS AND METHOD FOR VISUAL STIMULATION INDICATION 审中-公开
标题翻译：视觉刺激指征的装置和方法
公开(公告)号：WO2008011096A2
公开(公告)日：2008-01-24
申请号：PCT/US2007/016360
申请日：2007-07-19
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , VYAS, Neha , WEBBER, Donald, A. , REINHOLD, John, R. , ROY, Arup , CASTRO, Richard, Agustin , MCCLURE, Kelly, H. , GREENBERG, Robert, J.
发明人： VYAS, Neha , WEBBER, Donald, A. , REINHOLD, John, R. , ROY, Arup , CASTRO, Richard, Agustin , MCCLURE, Kelly, H. , GREENBERG, Robert, J.
IPC分类号： A61N1/36 , A61F9/08
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37241 , A61N1/37247 , G09B21/00 , G09B23/28
摘要： Methods and devices for verifying that proper visual stimulation is applied to the visual prostheses are described. In one of the methods, a retinal stimulation system implanted on a subject is simulated externally. An external testing device is also discussed.
摘要翻译：描述了用于验证适当视觉刺激应用于视觉假体的方法和装置。在其中一种方法中，外部模拟植入对象的视网膜刺激系统。还讨论了外部测试设备。

6. 发明申请

WO2008140980A1 VIDEO CONFIGURATION FILE EDITOR FOR VISUAL PROSTHESIS FITTING AND RELATED METHOD 审中-公开
标题翻译：视频配置文件编辑器，用于视觉配置和相关方法
公开(公告)号：WO2008140980A1
公开(公告)日：2008-11-20
申请号：PCT/US2008/062533
申请日：2008-05-02
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , ROY, Arup , ZHOU, Chunhong , MCCLURE, Kelly, H. , MCMAHON, Matthew, J. , CASPI, Avraham, I. , MAKSY, Pishoy , GREENBERG, Robert, J.
发明人： ROY, Arup , ZHOU, Chunhong , MCCLURE, Kelly, H. , MCMAHON, Matthew, J. , CASPI, Avraham, I. , MAKSY, Pishoy , GREENBERG, Robert, J.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/3605 , A61N1/37235 , A61N1/37247 , G06K9/4661 , G06T7/0012
摘要： A method of editing a video configuration file downloadable to or from a video processing unit of a fitting system for a visual prosthesis is shown. The visual prosthesis has a plurality of electrodes and the video configuration file defines mapping of a video signal captured from a camera of the visual prosthesis to an electrical signal for the electrodes. The editing controls a brightness map for an individual electrode or electrode groups, together with a temporal stimulation pattern to which an individual electrode or electrode groups are assigned. A related computer-operated system is also disclosed.
摘要翻译：示出了编辑可下载到视觉假体的装配系统的视频处理单元的视频配置文件的方法。视觉假体具有多个电极，并且视频配置文件定义从视觉假体的照相机捕获的视频信号到用于电极的电信号的映射。编辑控制单个电极或电极组的亮度图，以及分配单个电极组的时间刺激图案。还公开了一种相关的计算机操作系统。

7. 发明申请

WO2007035743A3 DOWNLOADABLE FILTERS FOR A VISUAL PROSTHESIS 审中-公开
公开(公告)号：WO2007035743A3
公开(公告)日：2007-03-29
申请号：PCT/US2006/036501
申请日：2006-09-18
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , MCCLURE, Kelly, H. , ROY, Arup , YADAV, Sumit , MAKSY, Pishoy , MELISTRUP, Peter
发明人： MCCLURE, Kelly, H. , ROY, Arup , YADAV, Sumit , MAKSY, Pishoy , MELISTRUP, Peter
IPC分类号： A61N1/36 , A61F9/08 , A61N1/05 , A61F2/14
摘要： The present invention is a method of neural stimulation and more specifically an improved method of providing flexible video/image possessing in a visual prosthesis by providing downloadable video filters. In a visual prosthesis, the input video image will, for the foreseeable future, be higher resolution than the output stimulation of the retina, optic nerve or visual cortex. This is due to limits of electrode array technology and the rapid advancement of video camera technology. It is therefore, advantageous to apply video processing algorithms (filters) to help provide the most useful information to the lower resolution electrode array. Different filters are more effective in different environments and for different subjects. Furthermore, filters will continue to improve over time. Examples of situation dependent filters include reverse image, contrast increasing, edge detection, segmentation using chromatic information and motion detection. Filters loaded in the video processing unit may be selected dynamically to suit the situation or the user's preference. It is therefore advantageous to provide flexibility in applying filters. However, it is also important to maintain the security necessary for a medical device. The present invention provides for an external (not implanted) video processing unit with downloadable video filters.

8. 发明申请

WO2008013937A2 VISUAL PROSTHESIS 审中-公开
标题翻译：视觉假体
公开(公告)号：WO2008013937A2
公开(公告)日：2008-01-31
申请号：PCT/US2007/016897
申请日：2007-07-27
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , MCCLURE, Kelly, H. , ROY, Arup , YADAV, Sumit , CASTRO, Richard, Agustin , MCCORD, Susan
发明人： MCCLURE, Kelly, H. , ROY, Arup , YADAV, Sumit , CASTRO, Richard, Agustin , MCCORD, Susan
IPC分类号： A61N1/36
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/3787
摘要： A visual prosthesis apparatus and a method for providing artificial vision are disclosed in the present disclosure. The visual prosthesis apparatus comprises a camera for capturing a video image, a video processing unit configured to convert the video image to stimulation patterns, and a retinal stimulation system configured stimulate neural tissue in a subjects eye based on the stimulation patterns. An artificial vision may be provided by capturing a video image, converting the video image to stimulation patterns, and stimulating neural tissue in a subjects eye based on the stimulation patterns.
摘要翻译：在本公开中公开了一种用于提供人造视觉的视觉假体装置和方法。视觉假体装置包括用于捕获视频图像的相机，配置成将视频图像转换为刺激图案的视频处理单元，以及配置的视网膜刺激系统基于刺激图案刺激对象眼睛中的神经组织。可以通过捕获视频图像，将视频图像转换成刺激图案，并基于刺激图案刺激对象眼睛中的神经组织来提供人工视觉。

9. 发明申请

WO2013052139A1 HYBRID FITTING FOR A VISUAL PROSTHESIS 审中-公开
标题翻译：混合配件用于视觉展示
公开(公告)号：WO2013052139A1
公开(公告)日：2013-04-11
申请号：PCT/US2012/000510
申请日：2012-10-03
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , DORN, Jessy , ROY, Arup , GREENBERG, Robert, J. , CASPI, Avraham, I
发明人： DORN, Jessy , ROY, Arup , GREENBERG, Robert, J. , CASPI, Avraham, I
IPC分类号： A61N1/05 , A61N1/36 , A61N1/372
CPC分类号： A61N1/36046 , A61N1/0543 , A61N1/37241 , A61N1/37247 , A61N1/37252
摘要： The present invention is an improved fitting and training system for a visual prosthesis. Fitting a visual prosthesis through automated means is challenging and fitting a visual prosthesis manually is tedious for clinician and patent, and provides great opportunity for error. A hybrid of computer controlled and manual fitting provides effective, efficient and controlled fitting process. The process includes testing a group of electrodes in random order by providing a prompt followed by stimulation and the patient responding if they saw a percept. After each set, a maximum likelihood algorithm is used to determine the next stimulation level, or if further stimulation is needed for each electrode.
摘要翻译：本发明是用于视觉假体的改进的装配和训练系统。通过自动化手段装配视觉假体是一个挑战，手动修复视觉假体对于临床医师和专利是乏味的，并为错误提供了很大的机会。计算机控制和手动配件的混合提供了有效，高效和可控制的装配过程。该过程包括通过提供紧随刺激的方式随机测试一组电极，并且如果他们看到感知，则患者作出响应。在每组之后，使用最大似然算法来确定下一个刺激水平，或者如果每个电极需要进一步的刺激。

10. 发明申请

WO2016044296A1 METHOD AND SYSTEM FOR DETECTING OBSTACLES FOR A VISUAL PROSTHESIS 审中-公开
标题翻译：用于检测视觉障碍物的障碍物的方法和系统
公开(公告)号：WO2016044296A1
公开(公告)日：2016-03-24
申请号：PCT/US2015/050226
申请日：2015-09-15
申请人： SECOND SIGHT MEDICAL PRODUCTS, INC. , GREENBERG, Robert, J. , ROY, Arup , CASPI, Avraham, I. , PATEL, Uday , WELCH, Mark, D.
发明人： GREENBERG, Robert, J. , ROY, Arup , CASPI, Avraham, I. , PATEL, Uday , WELCH, Mark, D.
IPC分类号： G06K9/00 , G09B21/00 , A61N1/36
CPC分类号： A61N1/36046 , A61N1/0543 , G06K9/00671 , G06K9/00805 , G09B21/008 , H04N5/2252 , H04N13/128 , H04N13/239 , H04N2013/0081
摘要： Systems and methods for detecting and displaying obstacles to visually impaired persons are disclosed. Images from a captured scene are analyzed to detect obstacles. A V-Disparity algorithm is employed to detect the ground plane and remove it from the images, thereby enhancing the capacity of retinal implants to display only obstacles. The system includes cameras to capture images; a processor with memory to detect obstacles in the captured images, to remove a ground plane, and to calculate a map of pixels representing the obstacles; and a retinal implant configured to receive the map of pixels and display the obstacles to a system user by electrically stimulating retinal nerves. The method includes synchronizing captured images and calculating a disparity map between the captured images to detect obstacles and remove a ground plane from processed images. A map of pixels representing the obstacle is transmitted to a retinal implant. Depth information may derive from stereo cameras, a time of flight camera or a structured light camera.
摘要翻译：公开了用于检测和显示障碍物的障碍物的系统和方法。分析捕获场景中的图像以检测障碍物。采用V-Disparity算法来检测地平面并将其从图像中去除，从而增强视网膜植入物仅显示障碍物的能力。该系统包括拍摄图像的相机; 具有存储器的处理器，用于检测所捕获的图像中的障碍物，以去除接地平面，并计算表示障碍物的像素的图; 以及视网膜植入物，被配置为接收像素的图并且通过电刺激视网膜神经将障碍物显示给系统用户。该方法包括同步捕获的图像并计算所捕获的图像之间的视差图，以检测障碍物并从经处理的图像中移除接地平面。将表示障碍物的像素的图像发送到视网膜植入物。深度信息可以来自立体相机，飞行时间相机或结构光照相机。

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