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1. 发明申请

WO2010044053A2 HYBRID ACTIVE LOCOMOTION TELEOPERATED ENDOSCOPIC CAPSULE 审中-公开
标题翻译：混合活性位置电除内囊
公开(公告)号：WO2010044053A2
公开(公告)日：2010-04-22
申请号：PCT/IB2009054491
申请日：2009-10-13
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT ANNA , MENCIASSI ARIANNA , DARIO PAOLO , VALDASTRI PIETRO , QUAGLIA CLAUDIO , BUSELLI ELISA , SIMI MASSIMILIANO
发明人： MENCIASSI ARIANNA , DARIO PAOLO , VALDASTRI PIETRO , QUAGLIA CLAUDIO , BUSELLI ELISA , SIMI MASSIMILIANO
IPC分类号： A61B1/273 , A61B1/31
CPC分类号： A61B1/273 , A61B1/00156 , A61B1/00158 , A61B1/041 , A61B1/31
摘要： A teleoperated endoscopic capsule for performing diagnostic and therapeutic activities in the gastro-intestinal tract of a patient, comprising a capsule body (1) extending longitudinally with a forward end (1a) and a rear end (1b), locomotion/orientation means (5) responsive to the action of a magnetic field controlled from the outside of the patient, image acquisition means (4) for acquiring images of at least predefined portions of the gastro-intestinal tract arranged at least at the forward end (1a) of the body (1), a power source (18), microprocessor means (16) for controlling the operation of the capsule, and means for receiving/transmitting signals(16, 17) from and towards an outside operator for transferring the acquired images and for sending control signals. Auxiliary locomotion means (6, 13, 15) are houseable inside the capsule in a rest condition and extendable from it to modify the external profile of the capsule. Sensors (23, 24) detect a stopped locomotion condition of the capsule and send a signal to the microprocessor means (16) to generate an actuation signal of the auxiliary locomotion means (6,13,15).
摘要翻译：一种用于在患者的胃肠道中执行诊断和治疗活动的远程操作的内窥镜胶囊，包括具有前端（1a）和后端（1b）纵向延伸的胶囊主体（1），运动/取向装置（5））响应于从患者外部控制的磁场的作用的图像获取装置（4），用于获取至少在身体的前端（1a）上布置的至少预定义的胃肠道部分的图像，（1），电源（18），用于控制胶囊的操作的微处理器装置（16）和用于从外部操作者接收/发送信号（16,17）的装置，用于传送所获取的图像并发送控制信号。辅助运动装置（6,13,15）可在静止状态下容纳在胶囊内部并且可从其延伸以修改胶囊的外部轮廓。传感器（23,24）检测胶囊的停止的运动状况，并向微处理器装置（16）发送信号以产生辅助运动装置（6,13,15）的致动信号。

2. 发明申请

WO2010119403A3 CELLULAR ELECTRIC STIMULATION MEDIATED BY PIEZOELECTRIC NANOTRANSDUCERS STIMULATED BY ULTRASONIC WAVES 审中-公开
标题翻译：由超声波刺激的压电纳米粒子介导的细胞电刺激
公开(公告)号：WO2010119403A3
公开(公告)日：2011-04-07
申请号：PCT/IB2010051602
申请日：2010-04-14
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT ANNA , FOND ISTITUTO ITALIANO DI TECNOLOGIA , CIOFANI GIANNI , RAFFA VITTORIA , DANTI SERENA , MENCIASSI ARIANNA , DARIO PAOLO , PETRINI MARIO , CUSCHIERI ALFRED
发明人： CIOFANI GIANNI , RAFFA VITTORIA , DANTI SERENA , MENCIASSI ARIANNA , DARIO PAOLO , PETRINI MARIO , CUSCHIERI ALFRED
IPC分类号： A61N1/36 , A61N1/05 , A61N1/20 , A61N1/32 , C12N5/00 , G01N33/58
CPC分类号： A61N1/205 , A61N1/326 , B82Y5/00
摘要： Piezoelectric nanotransducers for use in an in vivo treatment of cell stimulation through electrical stimulation comprising the steps of localizing the nanotransducers in a target site and inducing an electrical stimulus in the same site through external stimulation of nanotransducers by ultrasonic waves.
摘要翻译：用于通过电刺激的体内治疗细胞刺激的压电纳米转移体包括以下步骤：通过超声波对纳米传感器的外部刺激在目标部位定位纳米传感器并诱导相同部位的电刺激。

3. 发明申请

WO2008062378A3 NON INVASIVE METHOD OF ELECTROPORATION MEDIATED BY CARBON NANOTUBES AND DEVICE FOR PUTTING THE METHOD INTO PRACTICE 审中-公开
标题翻译：碳纳米管介导的非侵入式电穿孔方法及其实施方法
公开(公告)号：WO2008062378A3
公开(公告)日：2008-08-14
申请号：PCT/IB2007054754
申请日：2007-11-22
申请人： SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO SANT ANNA , RAFFA VITTORIA , MENCIASSI ARIANNA , PENSABENE VIRGINIA , CIOFANI GIANNI , DARIO PAOLO , VITTORIO ORAZIO
发明人： RAFFA VITTORIA , MENCIASSI ARIANNA , PENSABENE VIRGINIA , CIOFANI GIANNI , DARIO PAOLO , VITTORIO ORAZIO
IPC分类号： A61N1/32
CPC分类号： A61N1/327 , A61K41/0047 , A61N1/0424 , B82Y30/00 , C12M35/02 , C12N13/00
摘要： A non-invasive method for the electroporation of cells contained in a substrate wherein the cells are placed in contact with carbon nanotubes and then said substrate is subjected to the action of two orthogonal pulsed electric fields generated by means of two pairs of electrodes in contact with said substrate according to a specific time sequence in such a way that, when a pair of electrodes is active, the other pair of electrodes is deactivated and vice versa. A device for performing electroporation according to this method.
摘要翻译：一种用于电穿孔包含在基底中的细胞的非侵入性方法，其中将细胞放置成与碳纳米管接触，然后使所述基底经受两个正交脉冲电场的作用，所述两个正交脉冲电场通过两对接触的电极产生所述衬底按照特定的时间顺序以这样的方式，即当一对电极有效时，另一对电极不起作用，反之亦然。根据该方法进行电穿孔的装置。

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