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    • 9. 发明申请
    • MEDICAL DEVICE FOR DELIVERING BIOLOGICALLY ACTIVE MATERIAL
    • 提供生物活性物质的医疗设备
    • WO2006053159A2
    • 2006-05-18
    • PCT/US2005/040822
    • 2005-11-08
    • BOSTON SCIENTIFIC SCIMED, INC.ROSENTHAL, ArthurBARRY, James, J.MILLER, Matthew
    • ROSENTHAL, ArthurBARRY, James, J.MILLER, Matthew
    • A61L27/00A61F2/00A61F2/90A61K31/337A61K31/436A61K31/517A61K31/573A61K38/00
    • A61F2/90A61F2/91A61F2/915A61F2002/91525A61F2002/91533A61F2002/91575A61F2250/0014A61F2250/0067A61L31/16A61L31/18A61L2300/00
    • This invention relates generally to medical devices, such as stents, for delivering a biologically active material to a desired location within the body of a patient. In particular, the invention relates generally to a medical device for delivering a biologically active material to a surface of a body lumen. More particularly, the invention is directed to a medical device comprising two opposing end sections, each having a surface, and a middle portion. The middle portion comprises a plurality of struts and the two opposing end sections comprises non-structural elements. The end sections of the surface either (1) contain a greater amount of a biologically active material per unit length of the surface or (2) have a greater capacity per unit length to contain such material than the middle section of the surface than the middle section. The struts and the non-structural elements comprise biologically active material to the body tissue of a patient by inserting this medical device into the body of the patient. Still further, the invention is directed to a method of treating a body lumen surface by preventing or treating restenosis or hyperplasia, using the system of the invention. Still further, the invention is directed to a stent having a sidewall which comprises a middle section, a first end section and a second end section. The stent also comprises a band comprising a biologically active material. The band is connected to the first end section and/or second end section of the stent.
    • 本发明一般涉及用于将生物活性物质递送至患者体内期望位置的医疗装置,例如支架。 具体而言,本发明总体上涉及用于将生物活性物质递送至体腔表面的医疗装置。 更具体地说,本发明涉及一种医疗装置,其包括两个相对的端部部分,每个端部部分具有表面和中间部分。 中间部分包括多个支柱,并且两个相对的端部部分包括非结构元件。 表面的末端部分(1)每单位长度的表面包含更大量的生物活性材料或者(2)每单位长度具有更大的容量以容纳除表面的中间部分之外的材料比中间部分 部分。 通过将该医疗装置插入患者体内,支柱和非结构元件包括生物活性物质到患者的身体组织。 另外,本发明涉及使用本发明的系统通过预防或治疗再狭窄或增生来治疗体腔表面的方法。 更进一步,本发明涉及一种具有侧壁的支架,该侧壁包括中间部分,第一末端部分和第二末端部分。 支架还包含含有生物活性物质的带。 带被连接到支架的第一端部和/或第二端部。