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1. 发明申请

WO2022018107A1 ELECTRONIC SYSTEM FOR A DRUG DELIVERY DEVICE, DRUG DELIVERY DEVICE, AND ASSOCIATED METHOD 审中-公开
公开(公告)号：WO2022018107A1
公开(公告)日：2022-01-27
申请号：PCT/EP2021/070315
申请日：2021-07-21
申请人： SANOFI
发明人： DRAPER, Paul, Richard , O'HARE, Aidan, Michael , MARSH, William, Geoffrey, Arthur , GLEDHILL, Richard, Paul , MORRIS, Anthony, Paul , JENKINS, Daniel, Paul , EARWALKER, Tom, Alexander , GAZELEY, Oliver, Charles , HARVEY-COOK, Adam, Moyo , ALT, Stefan
IPC分类号： A61M5/315
摘要： An electronic system (1000) for a drug delivery device (1) is provided, the electronic system comprising: at least one user interface member (1600) configured to be manipulated by a user for performing a dose setting operation to set a dose of drug to be delivered by the drug delivery device and/or for performing a dose delivery operation for delivering a set dose, an electronic control unit (1100) configured to control operation of the electronic system, the electronic system having a first state and a second state, wherein the electronic system has an increased electrical power consumption in the second state as compared to the first state, an electrical signaling unit (1300) configured to provide at least one electrical signal when the user interface member is manipulated, wherein the user interface member is further configured to be manipulated for an activation operation, a manipulation evaluation unit (1150), the manipulation evaluation unit being operatively connected to the electrical signaling unit and configured to evaluate the at least one electrical signal of the signaling unit in order to determine whether the manipulation of the user interface member indicated by the at least one signal of the signaling unit qualifies as an activation operation, wherein the manipulation of the user interface member for the activation operation is different from the manipulation of the user interface member for the dose setting operation and for the dose delivery operation, and wherein the electronic control unit is configured to switch the electronic system into the second state of higher power consumption when the manipulation evaluation unit has confirmed that the manipulation qualifies as activation operation. Further, a drug delivery device, a method and a computer program product are disclosed.

2. 发明申请

WO2022263514A1 DRUG DELIVERY DEVICE AND METHOD FOR OPERATING A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2022263514A1
公开(公告)日：2022-12-22
申请号：PCT/EP2022/066312
申请日：2022-06-15
申请人： SANOFI
发明人： GAZELEY, Oliver, Charles , JONES, Matthew, Meredith , NANAYAKKARA, Prasannah
IPC分类号： A61M5/20 , A61M5/315 , F16D27/00 , F16D11/14 , F16D27/108 , F16D27/118 , F16D48/06
摘要： The present invention refers to a drug delivery device (1) and to a method of operating same. The drug delivery device (1) may comprise a housing (10; 32), a dial grip (12) manually operable by a user for setting an individual dose to be delivered by the drug delivery device (1), a dose setting and drive mechanism, which is configured to perform a dose setting operation in response to the operation of the dial grip (12) and which is configured to perform a dose delivery operation for delivering the set dose, a clutch (20) comprising two clutch members (21, 22; 31, 33; 43, 44) for rotationally coupling and de-coupling the dial grip (12) to the housing (10; 32) and/or to the dose setting and drive mechanism, at least one processor, a sensor arrangement (29, 30) connected to the at least one processor and operable to generate measurement data indicative of the dose setting operation, and a power source (28) connected to the at least one processor. The drug delivery device (1) further comprises a clutch actuator (23, 24; 23; 39, 23, 42) operable by the at least one processor to trigger a switch of the state of the clutch (20). The at least one processor is configured to operate the clutch actuator (23, 24; 23; 39, 23, 42) if the measurement data generated by the sensor arrangement (29, 30) reaches a threshold.

3. 发明申请

WO2022171548A1 A DOSE COUNTING SYSTEM 审中-公开
公开(公告)号：WO2022171548A1
公开(公告)日：2022-08-18
申请号：PCT/EP2022/052801
申请日：2022-02-07
申请人： SANOFI
发明人： EARWALKER, Tom Alexander , HARVEY-COOK, Adam, Moyo , HOBSON, Matthew, Francis , GAZELEY, Oliver, Charles
IPC分类号： A61M5/315 , G16H20/60 , G16H50/30
摘要： A dose counting system of an injection device or of a module configured to be used with or applied to an injection device, the dose counting system comprising a sensor arrangement comprising a first sensor configured to output a first signal and a second sensor configured to output a second signal, wherein the first sensor and the second sensor have an angular offset relative to each other and wherein the sensor arrangement is configured to detect movement of a rotary encoder system relative to the sensor arrangement during dosing of a medicament; and a processor configured to: detect a peak in the first signal when the first signal has increased by at least a predefined up threshold above the previous minimum of the first signal and the first signal exceeds the value of the second signal by more than a predetermined crossover threshold; subsequent to detecting a peak in the first signal, determine that a unit of medicament has been administered when the first signal drops from the peak by more than a predefined down threshold and the preceding peak occurred in the second signal; and determine a medicament dosage administered by the injection device by counting the administered units of medicament.

4. 发明申请

WO2022262992A1 A METHOD AND SYSTEM FOR ASSOCIATING DOSE RELATED DATA CAPTURED WITH AND STORED IN AN ADD-ON DEVICE TO A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2022262992A1
公开(公告)日：2022-12-22
申请号：PCT/EP2021/066591
申请日：2021-06-18
申请人： SANOFI
发明人： ALLERDINGS, Alexander , HARVEY-COOK, Adam, Moyo , PLUMPTRE, David Aubrey , GAZELEY, Oliver, Charles , VEASEY, Robert , O'HARE, Aiden Michael
IPC分类号： G16H20/13 , G16H40/60 , G16H10/60 , G16H20/17
摘要： A method for associating dose related data captured with and stored in an add-on device (10) to a drug delivery device (12) by means of an external computing device (14), the method comprising the steps: providing a drug delivery device (12) comprising identification information (126), providing an add-on device (10), comprising communication means (100) allowing the add-on device to communicate with an external computing device, means (102, 104, 106) for capturing and storing dose related data from a drug delivery device when mounted thereon, wherein the add-on device (10) is adapted to be releasably mounted on and in engagement with the drug delivery device (12),providing an external computing device (14) comprising, means (140, 142) for receiving the identification information from the drug delivery device, communication means (144) allowing the external control device to communicate with the add-on device (10), processor means (146), storage means (148) comprising a computer program, wherein the computer program configures the external computing device (14) to execute the following steps: receiving the identification information from the drug delivery device (12), obtaining information about the drug contained in the drug delivery device (12) based on the identification information, and labelling captured and stored dose related data based on the received information about the drug.

5. 发明申请

WO2022090274A1 ELECTRONIC SYSTEM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2022090274A1
公开(公告)日：2022-05-05
申请号：PCT/EP2021/079747
申请日：2021-10-27
申请人： SANOFI
发明人： ALT, Stefan , GAZELEY, Oliver, Charles , HARVEY-COOK, Adam, Moyo , INGRAM, Stephen , MASON, Craig, Ashley , O'HARE, Aidan, Michael , PLUMPTRE, David, Aubrey
IPC分类号： A61M5/315
摘要： 62 PAT20006-WO-PCT Abstract 5 Electronic system for a drug delivery device and drug delivery device An electronic system (1000) for a drug delivery device (1) is provided, the electronic system comprising: at least one user interface member (1600) configured to be manipulated by a user for performing a dose operation, e.g. a dose setting operation to set a dose of drug to be 10 delivered by the drug delivery device and/or a dose delivery operation for delivering a set dose, an electronic control unit (1100), the electronic control unit being configured to control operation of the electronic system, the electronic system having a first state and a second state, wherein the electronic system has an increased electrical power consumption in the second state as compared to the first state, an electrical signaling unit (1300), the signaling unit being configured 15 to provide an electrical signal indicative that the user interface member is being manipulated, wherein the electronic control unit is configured to switch the electronic system from the first state into the second state in response to the electrical signal, and wherein the user interface member comprises a first portion (1603) and a second portion (1604), wherein the first portion is movable relative to the second portion from a rest position of the first portion to a signaling 20 position of the first portion, wherein the signaling unit is configured to provide the electrical signal in response to the movement of the first portion relative to the second portion from the rest position into the signaling position. Figure 7A 25

6. 发明申请

WO2022129170A1 ELECTRODE SYSTEM, ELECTRONIC SYSTEM, DRUG DELIVERY DEVICE, AND A METHOD OF MANUFACTURING AN ELECTRONIC SYSTEM 审中-公开
公开(公告)号：WO2022129170A1
公开(公告)日：2022-06-23
申请号：PCT/EP2021/085890
申请日：2021-12-15
申请人： SANOFI
发明人： ALLERDINGS, Alexander , DRAKE, Jonathan, Jason , HARVEY-COOK, Adam, Moyo , GAZELEY, Oliver, Charles
IPC分类号： A61M5/24
摘要： The present disclosure relates to sensor electrode system (1345) for an electronic system (1000), the sensor electrode system comprising: a flexible conductor carrier (1350) which is electrically insulating; and an electrode arrangement (1360), wherein the electrode arrangement comprises at least two electrically conductive electrode tracks (1362, 1364, 1378), wherein the electrically conductive electrode tracks extend along the flexible conductor carrier, wherein the electrically conductive electrode tracks are electrically separated from one another along the conductor carrier, wherein one of the electrically conductive electrode tracks forms a sensing electrode (1366, 1376), and wherein the sensing electrode extends in a sensing region (1310, 1320) of the flexible conductor carrier. Furthermore, an electronic system, a drug delivery device and a method are disclosed.

7. 发明申请

WO2022029052A1 DRUG DELIVERY DEVICE AND MODULE HEREWITH 审中-公开
公开(公告)号：WO2022029052A1
公开(公告)日：2022-02-10
申请号：PCT/EP2021/071518
申请日：2021-08-02
申请人： SANOFI
发明人： GAZELEY, Oliver, Charles , TOPOREK, Maurice
IPC分类号： A61M5/31 , A61M5/315 , A61M2005/3126 , A61M2205/6027 , A61M5/3129 , A61M5/3135 , A61M5/3155 , A61M5/31568
摘要： The present invention refers to a drug delivery device, comprising a dose setting and driving assembly for dialing and dispensing a dose of a medicament from a cartridge of the drug delivery device. The dose setting and driving assembly comprises an outer housing (1, 11), a number sleeve (3) and a dose dial grip (4), wherein the number sleeve (3) and the dose dial grip (4) are rotatable relative to the outer housing (1, 11) during dose dialing and wherein the number sleeve (3) is rotatable relative to the outer housing (1, 11) during dose dispensing, while the dose dial grip (4) is axially displaceable and rotationally constrained to the outer housing (1, 11) during dose dispensing. The dose dial grip (4) comprises an outer skirt (6) partially protruding out of the outer housing (1, 11) and comprising a profiled gripping surface (7) at the proximal end of the dose dial grip (4). At least one of the number sleeve (3) and the skirt (6) of the dose dial grip (4) is provided with a series of circumferentially spaced conductive strips (12, 13, 14; 29) distributed around the outer circumference of the number sleeve (3) or the skirt (6). Further, a series of contacts (164, 166, 168; 30) is arranged within the outer housing (1, 11) biased to abut the conductive strips, wherein the conductive strips (12, 13, 14; 29) and/or the contacts (15; 164, 166, 168; 30) are directly accessible from outside the outer housing (1, 11).

8. 发明申请

WO2022018106A1 ELECTRONIC SYSTEM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2022018106A1
公开(公告)日：2022-01-27
申请号：PCT/EP2021/070314
申请日：2021-07-21
申请人： SANOFI
发明人： ALT, Stefan , GAZELEY, Oliver, Charles , HARVEY-COOK, Adam, Moyo , O'HARE, Aidan, Michael , INGRAM, Stephen , CALTON, Paul, Andrew
IPC分类号： A61M5/315
摘要： An electronic system (1000) for a drug delivery device (1) is provided, the electronic system comprising: at least one user interface member (1600, 11, 12), which is arranged to be manipulated by a user of the drug delivery device, wherein the user interface member has an exterior operation surface (1610, 1620) arranged and configured to be touched by a user of the drug delivery device during operation of the drug delivery device, and wherein the electronic system further comprises an electrical user proximity detection unit (1330) which is configured to generate a signal, when the user is close to or touches the exterior operation surface.

9. 发明申请

WO2021260161A2 IMPROVEMENTS OF AN OPTICAL SENSING SYSTEM OF A DRUG DELIVERY DEVICE 审中-公开
公开(公告)号：WO2021260161A2
公开(公告)日：2021-12-30
申请号：PCT/EP2021/067443
申请日：2021-06-25
申请人： SANOFI
发明人： MASON, Craig, Ashley , GAZELEY, Oliver, Charles , O'HARE, Aidan, Michael , HOBSON, Matthew, Francis , ALLERDINGS, Alexander
IPC分类号： G01D5/347 , A61M2205/3306 , A61M2205/3317 , A61M2205/3561 , A61M2205/50 , A61M5/24 , A61M5/31551 , G01D5/34723
摘要： Optical guiding means (10) configured for application with a drug delivery device having a movable dosage programming component (12) comprising a rotary encoder system and a sensor arrangement (14) comprising at least one optical sensor (16, 16') configured to detect movement of the movable dosage programming component (12) relative to the sensor arrangement (14) during dosing of a drug by emitting radiation (18, 18') and detecting reflections (20, 20') of the emitted radiation from the rotary encoder system, wherein the optical guiding means (10) are configured for guiding the radiation (18, 18') and reflections (20, 20') of the emitted radiation and comprise at least one light pipe (100, 100') having the shape of a frustum with a sensor-side surface (102, 102') and a encoder-side surface (104,104'). The at least one light pipe comprises one or more of the following features: the ratio of the sensor-side surface (102) and the encoder-side surface (104) being equal to or larger than about 1.0; the ratio of the surface (24) of a discreet encoding target (22) of the rotary encoder system and the encoder-side surface (104) being equal to or larger than 1.0; the encoder-side surface (104) having a roughness with an average feature size in the range of the wavelength of the radiation emitted by the at least one optical sensor (16, 16'); the sensor-side surface forms a single lens face (26) being moulded as part of the optical guiding means (10), wherein the single lens face (26) is formed as collimating optics.

10. 发明申请

WO2021116387A1 MODULAR SYSTEM FOR A DRUG DELIVERY DEVICE WITH ELECTRONIC AND CORRESPONDING MODULES AND METHOD 审中-公开
公开(公告)号：WO2021116387A1
公开(公告)日：2021-06-17
申请号：PCT/EP2020/085728
申请日：2020-12-11
申请人： SANOFI
发明人： PLUMPTRE, David, Aubrey , GAZELEY, Oliver, Charles , VEASEY, Robert , JUGL, Michael , BLANCKE, Stefan
IPC分类号： A61M5/315
摘要： Disclosed is a modular system (98) for a drug delivery device with electronic, comprising: - a mechanical module (100) that comprises: - a distal end (D) and a proximal end (P), and - a mechanism (106) that is configured to set and/or to deliver a dose of the drug out of the distal end (D) of the mechanical module (100), - an electronic module (120, 220) that comprises: - a detector unit (254, 264, 266), and - an electronic unit (240) that is operatively coupled to the detector unit (254, 264, 266), wherein the electronic module (120, 220) is removably mechanically coupled or coupleable to the mechanical module (100) in a proximal end region of the mechanical module (100).

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