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1. 发明申请

WO2016106094A2 METAL-ORGANIC FRAMEWORKS FOR THE CONVERSION OF LIGNOCELLULOSIC DERIVATIVES TO RENEWABLE PLATFORM CHEMICALS 审中-公开
标题翻译：用于向可再生平台化学品转化LELLOCELLULOSIC衍生物的金属有机框架
公开(公告)号：WO2016106094A2
公开(公告)日：2016-06-30
申请号：PCT/US2015/066474
申请日：2015-12-17
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , SANDIA CORPORATION , VIRDIA INC.
发明人： SATHITSUKSANOH, Noppadon , ALLENDORF, Mark D. , GEORGE, Anthe , JANSEN, Robert , LEONG, Kirsty , SIMMONS, Blake A. , SINGH, Seema , TRAVISANO III, Philip
IPC分类号： C07D307/50 , C07D307/48 , C08B1/00
CPC分类号： C07D307/46
摘要： Methods of processing lignocellulose using metal-organic frameworks (MOFs) to form renewable platform chemicals that may be used as initial feedstock are provided. Metal -organic frameworks react with lignocellulosic derivatives such as glucose and fructose to form 5-hydroxymethyl furfural (HMF) with high yield and high selectivity for FIMF production.
摘要翻译：提供了使用金属 - 有机骨架（MOFs）处理木质纤维素以形成可用作初始原料的可再生平台化学品的方法。金属 - 有机骨架与木质纤维素衍生物如葡萄糖和果糖反应形成5-羟甲基糠醛（HMF），具有高产率和高选择性的FIMF生产。

2. 发明申请

WO2014172042A1 SYNTHESIS OF NOVEL IONIC LIQUIDS FROM LIGNIN-DERIVED COMPOUNDS 审中-公开
标题翻译：来自LIGNIN衍生化合物的新型离子液体的合成
公开(公告)号：WO2014172042A1
公开(公告)日：2014-10-23
申请号：PCT/US2014/028684
申请日：2014-03-14
申请人： SANDIA CORPORATION , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： SOCHA, Aaron , SINGH, Seema , SIMMONS, Blake A. , BERGERON, Maxime
IPC分类号： C07C211/01 , B01F1/00
CPC分类号： C07D307/52 , C07C209/00 , C07C209/04 , C07C209/28 , C07C211/28 , C07C211/63 , C07C213/02 , C07C213/08 , C07C215/66 , C07C217/58 , C07D295/03 , C08H8/00 , C09K3/00 , C12P19/02 , C12P19/14 , H01M10/0569 , H01M2300/0037 , H01M2300/0045 , C07C215/50 , C07C211/27
摘要： Methods and compositions are provided for synthesizing ionic liquids from lignin derived compounds comprising: contacting a starting material comprising lignin with a depolymerization agent to depolymerize the lignin and form a mixture of aldehyde containing compounds; contacting the mixture of aldehyde containing compounds with an amine under conditions suitable to convert the mixture of aldehyde containing compounds to a mixture of amine containing compounds; and contacting the mixture of amine containing compounds with an acid under conditions suitable to form an ammonium salt, thereby preparing the ionic liquid.
摘要翻译：提供了用于从木质素衍生的化合物合成离子液体的方法和组合物，包括：使包含木质素的原料与解聚剂接触以使木质素解聚并形成含醛化合物的混合物; 在适于将含醛化合物的混合物转化为含胺化合物的混合物的条件下，使含醛化合物的混合物与胺接触; 并在适于形成铵盐的条件下使含胺化合物的混合物与酸接触，由此制备离子液体。

3. 发明申请

WO2012151214A1 GLYCOSIDE HYDROLASES HAVING MULTIPLE HYDROLASE ACTIVITIES 审中-公开
标题翻译：具有多种水解活性的甘氨酸水解剂
公开(公告)号：WO2012151214A1
公开(公告)日：2012-11-08
申请号：PCT/US2012/036007
申请日：2012-05-01
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , SANDIA CORPORATION , CHEN, Zhiwei , FRIEDLAND, Gregory D. , CHHABRA, Swapnil R. , CHIVIAN, Dylan C. , SIMMONS, Blake A.
发明人： CHEN, Zhiwei , FRIEDLAND, Gregory D. , CHHABRA, Swapnil R. , CHIVIAN, Dylan C. , SIMMONS, Blake A.
IPC分类号： C12N9/42
CPC分类号： C12P19/14 , C12N9/2434 , C12N9/2437 , C12P19/02 , C12Y302/01004
摘要： Glycoside hydrolases having at least two different hydrolytic activities are provided. In one embodiment, an isolated recombinant hydrolase having at least two activities selected from a group including asparagine derivatives,glutamine derivatives,and histidine derivatives is provided. Further, a method of generating free sugars from a mixture comprising asparagine derivatives, glutamine derivatives, and histidine derivatives is provided.
摘要翻译：提供具有至少两种不同水解活性的糖苷水解酶。在一个实施方案中，提供了具有选自包括天冬酰胺衍生物，谷氨酰胺衍生物和组氨酸衍生物的组中的至少两种活性的分离的重组水解酶。此外，提供了从包含天冬酰胺衍生物，谷氨酰胺衍生物和组氨酸衍生物的混合物产生游离糖的方法。

4. 发明申请

WO2021231096A1 USE OF ALKANOLAMINES FOR LIGNIN EXTRACTION IN THE PRETREATMENT OF BIOMASS 审中-公开
公开(公告)号：WO2021231096A1
公开(公告)日：2021-11-18
申请号：PCT/US2021/030023
申请日：2021-04-29
申请人： NATIONAL TECHNOLOGY AND ENGINEERING SOLUTIONS OF SANDIA, LLC , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人： ACHINIVU, Ezinne , GLADDEN, John M. , SIMMONS, Blake A.
IPC分类号： C12P7/02 , C12P7/10 , D21C3/00 , D21C3/20
摘要： The present invention provides for a method to produce a sugar compound from a biomass, the method comprising: (a) providing a first mixture comprising a solubilized biomass and an alkanolamine; (b) recovering at least part of the alkanolamine from the first mixture in order to separate the at least part of the alkanolamine from the first mixture; (c) optionally introducing an enzyme and/or a microbe to the first mixture such that the enzyme and/or microbe produce a sugar from the solubilized biomass; and, (d) optionally the sugar is separated from the first mixture.

5. 发明申请

WO2021168154A1 USE OF DISTILLABLE VOLATILE SALT FOR THE PRETREATMENT OF BIOMASS 审中-公开
公开(公告)号：WO2021168154A1
公开(公告)日：2021-08-26
申请号：PCT/US2021/018630
申请日：2021-02-18
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , NATIONAL TECHNOLOGY AND ENGINEERING SOLUTIONS OF SANDIA, LLC
发明人： ACHINIVU, Ezinne C. , GLADDEN, John M. , CHOUDHARY, Hemant , SIMMONS, Blake A.
IPC分类号： C12P19/00 , C12P7/04
摘要： The present invention provides for a method to produce a sugar from a biomass, the method comprising: (a) providing a first mixture comprising a solubilized biomass and a distillable acid-base conjugate salt (DABCS) or deep eutectic solvent (DES), wherein (i) the DABCS is a protic ionic liquid (PIL) or a protic salt comprising a DABCS cation and a DABCS anion, and (ii) the DES is any combination of Lewis or Brønsted acid and base comprising any anionic and/or cationic species that have sufficient vapor pressure so that it can be readily distilled; and (b) distilling at least part of the DABCS from the first mixture in order to separate the at least part of the DABCS from the first mixture.

6. 发明申请

WO2017087980A1 HIGH GRAVITY, FED-BATCH IONIC LIQUID BASED PROCESS FOR DECONSTRUCTING BIOMASS 审中-公开
标题翻译：基于FED-BATCH离子液体的高分解生物质解决方案
公开(公告)号：WO2017087980A1
公开(公告)日：2017-05-26
申请号：PCT/US2016/063195
申请日：2016-11-21
申请人： SANDIA CORPORATION
发明人： XU, Feng , SIMMONS, Blake A. , SINGH, Seema
IPC分类号： C12M1/33 , C12M1/00 , C12P7/10 , C12P7/06
CPC分类号： C12P19/14 , C12P19/02 , C12P2201/00
摘要： In one aspect, the present invention provides methods for preparing a fermentation product. The methods include pre-treating a mixture of biomass and ionic liquid, wherein the ionic liquid comprises a choline cation and the biomass comprises polysaccharide and lignin. The methods further include forming hydrolysates from the introduction of glycoside hydrolase to the pre-treated mixture at conditions sufficient to produce a sugar composition mixture for fermentation steps. The present invention provides methods for loading biomass mixtures in a batch-fed process, wherein the biomass slurries can be loaded into water or a concentrated sugar composition for hydrolysate production. The methods can be performed in a one-pot process, wherein the ionic liquids are present in the mixtures throughout each step. Aspects of the invention provide compositions of sugar composition mixtures and fermentation product mixtures.
摘要翻译：一方面，本发明提供了用于制备发酵产物的方法。所述方法包括预处理生物质和离子液体的混合物，其中离子液体包含胆碱阳离子并且生物质包含多糖和木质素。所述方法进一步包括在足以产生用于发酵步骤的糖组合物混合物的条件下从由糖苷水解酶引入预处理的混合物形成水解产物。本发明提供了用间歇进料方法装载生物质混合物的方法，其中生物质浆液可以被装载到水或浓缩的糖组合物中用于水解产物的生产。该方法可以在一锅法中进行，其中离子液体在整个每个步骤中都存在于混合物中。本发明的方面提供了糖组合物混合物和发酵产物混合物的组合物。

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