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    • 2. 发明申请
    • PROCESS FOR PREPARATION OF HERBICIDAL CARBOXYLIC ACID SALTS
    • 制备除草剂羧酸盐的方法
    • WO2015062286A1
    • 2015-05-07
    • PCT/CN2014/080265
    • 2014-06-19
    • ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED
    • BRISTOW, James, Timothy
    • C07C51/41C07C59/70C07C63/08A01N37/10A01N39/02A01N43/70
    • C07C51/412A01N25/12A01N33/08A01N37/10A01N37/40A01N39/04A01N43/40A01N43/42C07C51/42C07C51/47C07C59/68C07C65/21C07C213/08C07C215/08C07D213/79C07D213/803C07D215/18
    • A process for preparing a herbicidally active carboxylic acid salt is disclosed, the process comprising the steps of: i) combining a carboxylic acid with a high-boiling, water-immiscible organic solvent to obtain a solution or slurry; ii) treating the solution or slurry produced in step (i) with a base to form a carboxylic acid salt; iii) removing solvent from the mixture produced in step (ii) to obtain a carboxylic acid salt cake; and v) drying the cake obtained in step (iii). The process is particularly suitable for preparing a salt of dicamba. A process for preparing dicamba-sodium comprises: (1) dissolving a carboxylic acid consisting essentially of dicamba in a high-boiling water-immiscible inert organic solvent to get a solution or slurry; (2) treating the dicamba solution or slurry in Step 1 with a base selected from sodium hydroxide, sodium bicarbonate and mixtures thereof, at a molar ratio of 1:0.97±0.6% to form dicamba-sodium; (3) centrifuging the reaction mixture in Step 2 to obtain dicamba-sodium salt cake; and (4) drying the dicamba-sodium cake obtained in Step 3 to get a dry dicamba- sodium consistently having a pH value between about 7 and 10 when dissolved in water.
    • 公开了一种制备除草活性羧酸盐的方法,该方法包括以下步骤:i)将羧酸与高沸点的与水不混溶的有机溶剂混合以获得溶液或浆料; ii)用碱处理在步骤(i)中产生的溶液或浆料以形成羧酸盐; iii)从步骤(ii)中制备的混合物中除去溶剂,得到羧酸盐饼; 和v)干燥步骤(iii)中获得的饼。 该方法特别适用于制备麦草畏的盐。 制备麦草畏钠的方法包括:(1)将基本上由麦草畏草组成的羧酸溶解在高沸水不溶混的惰性有机溶剂中以得到溶液或浆液; (2)以1:0.97±0.6%的摩尔比,用选自氢氧化钠,碳酸氢钠和其混合物的碱处理步骤1中的麦草畏溶液或淤浆,形成麦草畏; (3)在步骤2中离心反应混合物,得到麦草畏钠盐饼; 和(4)干燥步骤3中获得的麦草畏钠饼以获得当溶解在水中时,一般具有约7至10的pH值的干燥的麦角氨酸钠。