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1. 发明申请

WO0009120A8 NEW USE OF TAXOID DERIVATIVES 审中-公开
标题翻译：新的使用紫杉醇衍生物
公开(公告)号：WO0009120A8
公开(公告)日：2001-04-05
申请号：PCT/EP9906291
申请日：1999-08-13
申请人： RHONE POULENC RORER SA , BISSERY MARIE CHRISTINE , VRIGNAUD PATRICIA , ROBERTS SIMON , BREALEY CLIVE
发明人： BISSERY MARIE-CHRISTINE , VRIGNAUD PATRICIA , ROBERTS SIMON , BREALEY CLIVE
IPC分类号： C07D305/14 , A61K31/335 , A61K31/337 , A61K38/00 , A61K38/19 , A61K38/20 , A61K38/21 , A61K39/395 , A61K45/00 , A61K45/06 , A61P35/00
CPC分类号： A61K31/335 , A61K31/337 , A61K38/191 , A61K38/20 , A61K38/212 , A61K38/215 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a new use of taxoid derivatives. It relates more precisely to a method for treating abnormal cell proliferation in the brain of mammals including men by administrating a taxoid derivative.
摘要翻译：本发明涉及紫杉烷衍生物的新用途。其更具体地涉及通过施用紫杉烷衍生物来治疗包括男性在内的哺乳动物的脑中的异常细胞增殖的方法。

2. 发明申请

WO0010547A3 NEW USE OF TAXOID DERIVATIVES 审中-公开
标题翻译：新的使用紫杉醇衍生物
公开(公告)号：WO0010547A3
公开(公告)日：2000-06-29
申请号：PCT/EP9906292
申请日：1999-08-18
申请人： AVENTIS PHARMA SA , BISSERY MARIE CHRISTINE , VRIGNAUD PATRICIA , ROBERTS SIMON , BREALEY CLIVE
发明人： BISSERY MARIE-CHRISTINE , VRIGNAUD PATRICIA , ROBERTS SIMON , BREALEY CLIVE
IPC分类号： C07D305/14 , A61K31/337 , A61P35/00 , A61P37/02 , A61K31/335
CPC分类号： A61K31/337
摘要： The present invention relates a new use of taxoid derivatives. It relates more precisely to a method for treating abnormal cell proliferation of different resistant cell lines expressing multidrug resistance P-glycoprotein. This type of cells are representative of colon cancer cells. The products of the present invention are also usable to treat the colon cancer of mammals including men. The preferred compound is 4 alpha -acetoxy-2 alpha -benzoyloxy-5 beta , 20-epoxy-1 beta -hydroxy-7 beta -dimethoxy-9-oxo-11-taxen-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate.
摘要翻译：本发明涉及紫杉烷衍生物的新用途。更具体地说，涉及用于治疗表达多药耐药性P-糖蛋白的不同抗性细胞系的异常细胞增殖的方法。这种类型的细胞是结肠癌细胞的代表。本发明的产品也可用于治疗包括男性在内的哺乳动物的结肠癌。优选的化合物是4α-乙酰氧基-2α-苯甲酰氧基-5β，20-环氧-1β-羟基-7β-二甲氧基-9-氧代-11-亚苄基-13α-基（2R，3S）-3 - 叔丁氧基羰基-2-羟基-3-苯基丙酸酯。

3. 发明申请

WO2006114618A3 IMPROVED CONNECTION OF SECURITY ALARM COMPONENTS 审中-公开
标题翻译：改进安全警报组件的连接
公开(公告)号：WO2006114618A3
公开(公告)日：2007-03-08
申请号：PCT/GB2006001517
申请日：2006-04-26
申请人： TEXECOM LTD , BROWN CLYM , ROBERTS SIMON
发明人： BROWN CLYM , ROBERTS SIMON
IPC分类号： G08B3/10 , G08B29/04
CPC分类号： G08B29/046 , G08B3/10
摘要： An alarm component such as a bell box is formed from a pair of interconnected moulded plastic parts (10) held together by complementary locking members (13, 26) provided around the edge of each respective part which engage to lock the edges together. The parts (10, 24) are finally secured by a screw fastener. To avoid loss of the fastener, the fastener is held captive within the structure of one part of one component and operation of the fastener acts to secure or release the locking members (13, 26) thereby allowing or preventing access to the interior of the component.
摘要翻译：诸如钟形盒的报警部件由一对互连的模制塑料部件（10）形成，所述模制塑料部件（10）通过互相配合的锁定部件（13,26）围绕各个部件的边缘设置，所述互锁锁定部件接合以将边缘锁定在一起。部件（10,24）最后通过螺丝紧固件固定。为了避免紧固件的损失，紧固件被保持在一个部件的一部分的结构内，并且紧固件的操作用于固定或释放锁定构件（13,26），从而允许或阻止进入组件的内部。

4. 发明申请

WO2009127863A4 TILT LIMIT AND LOCKING MECHANISM FOR A CHAIR 审中-公开
标题翻译：椅子的倾斜限制和锁定机构
公开(公告)号：WO2009127863A4
公开(公告)日：2010-06-10
申请号：PCT/GB2009050363
申请日：2009-04-14
申请人： SIMCLAR SEATING TECHNOLOGIES L , ROBERTS SIMON , JONES MARK
发明人： ROBERTS SIMON , JONES MARK
IPC分类号： A47C1/032
CPC分类号： A47C1/03255 , A47C1/03238
摘要： A chair has a back (2) and a seat part (1), which are pivoted at an axis (8), and to a fixed body (5) at a main pivot (7). An arm (16) is connected to the axis (8) by a link which is displaced by pivoting of the back (2), thereby moving the (arm16) reciprocally. The other end of the arm (16) is connected to a secondary pivot (15), which orbits the main pivot (7) on a further link. Main pivot (7) carries a latch (14) which is adapted to engage withstepped detents (21) on the upper edge of arm (16), while secondary pivot (15) carries a second latch (13) which is adapted to engage with stepped detents (18) formed in the base of body (5). The (arm16) is displaced by rotation of the link to pivot (8) so that latch (14) can engage with different ones of the detents (21), and at the same time displaceable latch (13) to engage with different ones of the fixed detents (18). Respective pivoted bell-crank levers (11) and (12) are also pivoted on axis (8), and have first respective ends which bear on respective latches (13 and 14), and second ends which bear a (cam10) carried on an axis which can be turned by a handle, to engage or disengage the latches. A tilt limiting device is provided by latch (13,14) engaging with stepped detents (119).
摘要翻译：椅子具有在轴线（8）处枢转的后部（2）和座椅部分（1），以及在主枢轴（7）处的固定体（5）。臂（16）通过由后部（2）的枢转而移动的连杆连接到轴线（8），从而使（臂16）往复移动。臂（16）的另一端连接到辅助枢轴（15），该枢轴绕枢轴（7）在另一个连杆上轨道运动。主枢轴（7）承载一个闩锁（14），该闩锁适于与臂（16）的上边缘上的步进棘爪（21）接合，而次枢轴（15）承载第二闩锁（13）形成在主体（5）的基部中的台阶式制动器（18）。（臂16）通过连杆的旋转而枢转枢转（8），使得闩锁（14）可以与不同的棘爪（21）接合，并且同时可移动的闩锁（13）与不同的棘爪固定掣子（18）。相应的枢轴式曲柄杆（11）和（12）也在轴线（8）上枢转，并且具有承载在相应的闩锁（13和14）上的第一相应的端部，并且承载一个（cam10）的第二端承载在轴可以由手柄转动，以使锁闩接合或脱开。倾斜限制装置由与步阶棘爪（119）接合的闩锁（13,14）提供。

5. 发明申请

WO2009155143A3 MONITORING HANDRAILS TO REDUCE FALLS 审中-公开
标题翻译：监督手段减少失败
公开(公告)号：WO2009155143A3
公开(公告)日：2010-03-25
申请号：PCT/US2009046455
申请日：2009-06-05
申请人： INTEL CORP , BEHAN JULIE , DISHONGH TERRY , O'DONOVAN KAROL , BURNS ADRIAN , ROBERTS SIMON
发明人： BEHAN JULIE , DISHONGH TERRY , O'DONOVAN KAROL , BURNS ADRIAN , ROBERTS SIMON
IPC分类号： G08B21/02 , G08B21/18
CPC分类号： B66B29/005 , E04F11/1802 , E04F2011/1872
摘要： A monitor, which may be closely associated with a handrail, may determine the amount of force applied to the handrail. The monitor may also determine the pattern in which force is applied to the handrail in order to assess how the user is contacting the handrail. The user's application of force to the handrail can be monitored along the course of movement along the handrail and may be compared to historical usage patterns.
摘要翻译：可能与扶手密切相关的监视器可以确定施加到扶手的力的量。监视器还可以确定施加到扶手的力的模式，以便评估用户如何与扶手接触。可以沿着扶手的移动过程来监视用户对扶手的施加力，并且可以将其与历史使用模式进行比较。

6. 发明申请

WO2009127863A3 TILT LIMIT AND LOCKING MECHANISM FOR A CHAIR 审中-公开
标题翻译：倾斜限制和锁定机制
公开(公告)号：WO2009127863A3
公开(公告)日：2010-01-21
申请号：PCT/GB2009050363
申请日：2009-04-14
申请人： SIMCLAR SEATING TECHNOLOGIES L , ROBERTS SIMON , JONES MARK
发明人： ROBERTS SIMON , JONES MARK
IPC分类号： A47C1/032
CPC分类号： A47C1/03255 , A47C1/03238
摘要： A chair has a back (2) and a seat part (1), which are pivoted at an axis (8), and to a fixed body (5) at a main pivot (7). An arm (16) is connected to the axis (8) by a link which is displaced by pivoting of the back (2), thereby moving the (arm16) reciprocally. The other end of the arm (16) is connected to a secondary pivot (15), which orbits the main pivot (7) on a further link. Main pivot (7) carries a latch (14) which is adapted to engage withstepped detents (21) on the upper edge of arm (16), while secondary pivot (15) carries a second latch (13) which is adapted to engage with stepped detents (18) formed in the base of body (5). The (arm16) is displaced by rotation of the link to pivot (8) so that latch (14) can engage with different ones of the detents (21), and at the same time displaceable latch (13) to engage with different ones of the fixed detents (18). Respective pivoted bell-crank levers (11) and (12) are also pivoted on axis (8), and have first respective ends which bear on respective latches (13 and 14), and second ends which bear a (cam10) carried on an axis which can be turned by a handle, to engage or disengage the latches. A tilt limiting device is provided by latch (13,14) engaging with stepped detents (119).
摘要翻译：椅子具有在轴线（8）处枢转的靠背（2）和座位部分（1）以及在主枢轴（7）处的固定体（5）。臂（16）通过连接件与轴（8）连接，该连接件通过背部（2）的枢转而移位，由此使（臂16）往复移动。臂（16）的另一端连接到辅助枢轴（15），辅助枢轴（15）在另一个连杆上围绕主枢轴（7）旋转。主枢轴7带有一个适于与臂16的上边缘上的制动掣子21啮合的闩锁14，而辅助枢轴15带有一个第二闩锁13，形成在主体（5）的基部中的阶梯式制动器（18）。（臂16）通过连杆转动到枢轴（8）而移动，使得闩锁（14）可以与不同的止动件（21）接合，并且同时可移动的闩锁（13）与不同的固定棘爪（18）。各枢轴式曲柄杠杆（11）和（12）也在轴线（8）上枢转，并且具有分别支承在相应的闩锁（13和14）上的第一端部和支承（凸轮10）可以通过手柄转动的轴，以啮合或脱离锁闩。倾斜限制装置通过与阶梯形棘爪（119）接合的闩锁（13,14）提供。

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