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    • 1. 发明申请
    • THERAPEUTIC AGENTS
    • 治疗药剂
    • WO2007132273A2
    • 2007-11-22
    • PCT/GB2007/050269
    • 2007-05-17
    • RECKITT & COLMAN (OVERSEAS) LIMITEDSTRODTHOLZ, IrisSCHMIDT, Timm
    • STRODTHOLZ, IrisSCHMIDT, Timm
    • A61K8/31A61K8/46A61K8/81A61K8/92A61Q19/10
    • A61Q19/10A61K8/31A61K8/463A61K8/8117A61K8/922A61Q19/00
    • A rinse-off composition suitable for topical application comprising a skincare active ingredient capable of regulating the barrier properties of the skin and a carrier therefor, said carrier comprising a) a physiologically acceptable oil present in an amount of at least 25% by weight of the composition; b) a surfactant selected from an anionic surfactant, a non-ionic surfactant or a mixture thereof; and c) a miscible non-aqueous film former. The invention particularly relates to skincare active ingredients which are substantially insoluble in water. The composition is especially useful in the treatment of eczema, psoriasis, rosacea-prone skin, inflamed skin and acne. On applying the composition to the skin and rinsing off, an emulsion is formed which may be washed away and a film deposited on the skin comprising a therapeutically effective amount of said skincare active.
    • 适用于局部应用的漂洗组合物,其包含能够调节皮肤的阻隔性能的护肤活性成分及其载体,所述载体包含a)以至少25重量%的量存在的生理上可接受的油, 组成; b)选自阴离子表面活性剂,非离子表面活性剂或其混合物的表面活性剂; 和c)可混溶的非水性成膜剂。 本发明特别涉及基本上不溶于水的护肤活性成分。 该组合物特别适用于治疗湿疹,牛皮癣,易发红斑痤疮的皮肤,发炎皮肤和痤疮。 在将组合物施用于皮肤并漂洗时,形成可以被洗去的乳液,并且沉积在皮肤上的膜包含治疗有效量的所述护肤活性物质。