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1. 发明申请

WO2004093993A1 HAIR GROWTH 审中-公开
标题翻译：头发生长
公开(公告)号：WO2004093993A1
公开(公告)日：2004-11-04
申请号：PCT/CA2003/000603
申请日：2003-04-23
申请人： QLT INC. , HOULE, Jean-Marie , HUNT, David, W., C.
发明人： HOULE, Jean-Marie , HUNT, David, W., C.
IPC分类号： A61N5/06
CPC分类号： A61N5/0617 , A61N5/062
摘要： It has been discovered that photodynamic therapy (PDT) can stimulate an increase in hair count numbers and restore hair growth in areas of hair loss. A method according to the present invention comprises: a) administering an effective and/or sufficient amount of a photosensitizer to the target skin; b) irradiating the target skin with energy comprising one or more wavelength capable of activating said photosensitizer for a time period sufficient to activate the photosensitizer; wherein the there is an increase in hair count numbers in the treated area. In one aspect of the present invention, there is a 2 % or more increase in the number of terminal hairs within 3 months.
摘要翻译：已经发现，光动力疗法（PDT）可以刺激头发数量的增加并且在脱发区域恢复毛发生长。根据本发明的方法包括：a）向目标皮肤施用有效和/或足够量的光敏剂; b）用能够激活所述光敏剂的能量包括一种或多种能够激活光敏剂的时间段的能量照射目标皮肤; 其中处理区域的毛发数量增加。在本发明的一个方面，3个月以内的头发数量增加2％以上。

2. 发明申请

WO2005074987A1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF ACNE 审中-公开
标题翻译：用于治疗ACNE的光化疗法
公开(公告)号：WO2005074987A1
公开(公告)日：2005-08-18
申请号：PCT/CA2005/000141
申请日：2005-02-04
申请人： QLT INC. , CURAUDEAU, Alain, H. , NEYNDORFF, Herma, C. , TAO, Jing-Song , LAM, Morgan, Chun , CURRY, Patrick, Mark , RUBINCHIK, Valery , HUNT, David, W., C.
发明人： CURAUDEAU, Alain, H. , NEYNDORFF, Herma, C. , TAO, Jing-Song , LAM, Morgan, Chun , CURRY, Patrick, Mark , RUBINCHIK, Valery , HUNT, David, W., C.
IPC分类号： A61K41/00
CPC分类号： A61K31/07 , A61K31/203 , A61K31/409 , A61K31/555 , A61K41/0061 , A61K41/0071 , A61K41/0076 , A61N5/062
摘要： The present method involves the photodynamic treatment of acne vulgaris. The method involves the topical administration of a photosensitizer composition comprising hydrophobic green porphyrins such as lemuteporfin, polyethylene glycol and skin penetration enhancers such as oleyl alcohol and TRANSCUTOL TM to acne-affected skin and subsequent exposure of that skin to energy of a wavelength of activating the photosensitizer.
摘要翻译：本方法涉及寻常痤疮的光动力治疗。该方法包括局部施用光敏剂组合物，其包含疏水性绿色卟啉，例如lemuteporfin，聚乙二醇和皮肤渗透促进剂如油醇和TRANSCUTOL TM，用于受痤疮影响的皮肤，随后将该皮肤暴露于波长激活光敏剂。

3. 发明申请

WO2005120572A1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF HYPERACTIVE SEBACEOUS GLAND DISORDERS USING TOPICALLY APPLIED HYDROPHOBIC GREEN PORPHYRINS 审中-公开
标题翻译：使用主要应用的疏水性绿色磷脂治疗高血压性鼻炎疾病的光化疗法
公开(公告)号：WO2005120572A1
公开(公告)日：2005-12-22
申请号：PCT/CA2005/000154
申请日：2005-02-08
申请人： QLT INC. , CURAUDEAU, Alain, H. , NEYNDORFF, Herma, C. , TAO, Jing-Song , LEVY, Julia, G. , HUNT, David, W., C.
发明人： CURAUDEAU, Alain, H. , NEYNDORFF, Herma, C. , TAO, Jing-Song , LEVY, Julia, G. , HUNT, David, W., C.
IPC分类号： A61K41/00
CPC分类号： A61K31/07 , A61K31/203 , A61K31/409 , A61K31/555 , A61K41/0061 , A61K41/0071 , A61K41/0076 , A61N5/062
摘要： The present method involves the photodynamic treatment of hyperactive gland disorders. The method involves the topical administration of a photosensitizer composition comprising hydrophobic and/or lipophilic green porphyrins such as lemuteporfin, polyethylene glycol and skin penetration enhancers such as oleyl alcohol and TRANSCUTOL TM to affected skin and subsequent exposure of that skin to energy of a wavelength capable of activating the photosensitizer.
摘要翻译：本方法涉及光动力学治疗多发性腺体疾病。该方法涉及局部施用包含疏水性和/或亲脂性绿色卟啉如雷米他芬，聚乙二醇和皮肤渗透增强剂如油醇和TRANSCUTOL TM的光敏剂组合物，以影响皮肤并随后暴露于皮肤的能量波长能够激活光敏剂。

4. 发明申请

WO2003039596A1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF HAIR LOSS 审中-公开
标题翻译：光动力疗法治疗脱发
公开(公告)号：WO2003039596A1
公开(公告)日：2003-05-15
申请号：PCT/CA2002/001711
申请日：2002-11-08
申请人： QLT INC. , SIMKIN, Guillermo, O. , RICHTER, Anna, M. , HUNT, David, W., C. , NORTH, John, Robert , LUTWYCHE, Peter , BOCH, Ronald, Erwin
发明人： SIMKIN, Guillermo, O. , RICHTER, Anna, M. , HUNT, David, W., C. , NORTH, John, Robert , LUTWYCHE, Peter , BOCH, Ronald, Erwin
IPC分类号： A61K41/00
CPC分类号： A61K8/4913 , A61K9/0014 , A61K9/0019 , A61K31/40 , A61K31/555 , A61K41/0071 , A61K47/10 , A61K2800/434 , A61K2800/81 , A61N5/0617 , A61N5/062 , A61Q7/00
摘要： Photodynamic therapy (PDT) is used to stimulate and/or restore hair growth in areas of hair loss. Methods and compositions relating to PDT treatment for alopecia are disclosed. In light of PDT use to remove unwanted hair by inactivating or destroying hair follicles or destroying the tissue feeding the hair follicles, such methods and compositions relate to a surprising and unexpected discovery. PDT permits a means to treat conditions relating to hair loss such as androgenic alopecia, alopecia areata and drug-induced alopecia.
摘要翻译：光动力疗法（PDT）用于刺激和/或恢复脱发区域的毛发生长。公开了涉及用于脱发的PDT治疗的方法和组合物。鉴于通过灭活或破坏毛囊或破坏供给毛囊的组织而使用PDT去除不想要的毛发，此类方法和组合物涉及令人惊讶且意想不到的发现。 PDT允许治疗与脱发有关的疾病，例如雄激素性脱发，斑秃和药物引起的脱发。

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