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    • 4. 发明申请
    • COMPOSITIONS COMPRISING A POLYSACCHARIDE COMPONENT AND ONE OR MORE COATING LAYERS
    • 包含多糖组分和一个或多个涂层的组合物
    • WO2004073636A3
    • 2005-04-14
    • PCT/US2004004653
    • 2004-02-18
    • PROCTER & GAMBLEMYATT GRAHAM JOHNCIMILUCA PAUL ALFRED
    • MYATT GRAHAM JOHNCIMILUCA PAUL ALFRED
    • A61K20060101A61K9/00A61K9/16A61K9/68A61K31/715A61K35/78
    • A61K9/1652A61K9/167A61K9/5073Y10S514/884Y10S514/892
    • The present disclosure provides compositions comprising a plurality of agglomerates comprising a polysaccharide component comprising xylose and arabinose, wherein the ratio of xylose to arabinose is at least about 3 : 1, by weight; wherein the compositions further comprise: (i) optionally, a first surrounding layer which surrounds the agglomerate, wherein the first surrounding layer is a hydrophobic layer; and (ii) optionally, a second surrounding layer which surrounds the agglomerate, wherein the second surrounding layer is a hydrophilic layer; wherein the compositions comprise at least one of the first surrounding layer and the second surrounding layer, and wherein when the agglomerate comprises the first surrounding layer and the second surrounding layer then the first surrounding layer is a preceding layer relative to the second surrounding layer. In another embodiment, the disclosure provides compositions comprising a plurality of polysaccharide particles, wherein the polysaccharide particles comprise a polysaccharide component comprising xylose and arabinose, wherein the ratio of the xylose to the arabinose is at least about 3 : 1, by weight, and wherein the polysaccharide particles have a mean particle size distribution of from about 0.001 microns to about 150 microns, wherein the polysaccharide particles each, independently, comprise: (i) optionally, a first surrounding layer which surrounds the particle, wherein the first surrounding layer is a hydrophobic layer; and (ii) optionally, a second surrounding layer which surrounds the particle, wherein the second surrounding layer is a hydrophilic layer; wherein the polysaccharide particles each, independently, comprise at least one of the first surrounding layer and the second surrounding layer, and wherein when the particle comprises the first surrounding layer and the second surrounding layer then the first surrounding layer is a preceding layer relative to the second surrounding layer. The present compositions are useful for the treatment of a variety of benefits, including providing treatment for gastrointestinal conditions or providing other gastrointestinal benefits.
    • 本公开提供了包含多个附聚物的组合物,其包含包含木糖和阿拉伯糖的多糖组分,其中木糖与阿拉伯糖的比例为至少约3:1重量比; 其中所述组合物还包含:(i)任选的包围所述附聚物的第一环绕层,其中所述第一环绕层是疏水层; 和(ii)任选地,围绕所述附聚物的第二周围层,其中所述第二周围层是亲水层; 其中所述组合物包括所述第一环绕层和所述第二环绕层中的至少一个,并且其中当所述附聚物包含所述第一环绕层和所述第二环绕层时,所述第一环绕层是相对于所述第二环绕层的先前层。 在另一个实施方案中,本公开提供了包含多个多糖颗粒的组合物,其中所述多糖颗粒包含包含木糖和阿拉伯糖的多糖组分,其中所述木糖与阿拉伯糖的比例为至少约3:1重量比,并且其中 多糖颗粒具有约0.001微米至约150微米的平均粒度分布,其中多糖颗粒各自独立地包含:(i)任选的包围颗粒的第一环绕层,其中第一环绕层为 疏水层; 和(ii)任选地,围绕所述颗粒的第二周围层,其中所述第二周围层是亲水层; 其中所述多糖颗粒各自独立地包含所述第一环绕层和所述第二环绕层中的至少一个,并且其中当所述颗粒包括所述第一环绕层和所述第二环绕层时,所述第一环绕层是相对于 第二周边层。 本发明的组合物可用于治疗各种益处,包括为胃肠道病症提供治疗或提供其它胃肠道益处。
    • 7. 发明申请
    • COMPOSITIONS COMPRISING A DEFINED POLYSACCHARIDE COMPONENT
    • 包含定义的多糖组分的组合物
    • WO2004073637A3
    • 2004-11-25
    • PCT/US2004004654
    • 2004-02-18
    • PROCTER & GAMBLEMYATT GRAHAM JOHNCIMILUCA PAUL ALFRED
    • MYATT GRAHAM JOHNCIMILUCA PAUL ALFRED
    • A61K20060101A61K9/00A61K9/16A61K9/68A61K31/715A61K35/78
    • A61K9/0095A61K9/10A61K9/1652A61K31/715A61K47/12A61K47/36Y10S514/884Y10S514/892
    • The present disclosure provides compositions comprising an extracted portion of psyllium seed in combination with one or more of a binder, suspending agent, or edible acid. In particular, the present invention is directed to compositions comprising: (a) a polysaccharide component comprising xylose and arabinose, wherein the ratio of xylose to arabinose is at least about 3 : 1, by weight; and (b) a dispersing component selected from the group consisting of binders, suspending agents, edible acids, and mixtures thereof. In a preferred embodiment, the compositions further comprise an aqueous liquid, for example, water or juice (e.g., fruit or vegetable juice). As such, the present invention further relates to methods of preparing a product comprising admixing the present compositions with an aqueous liquid. The present compositions are useful for the treatment of a variety of benefits, including providing treatment for gastrointestinal conditions or providing other gastrointestinal benefits.
    • 本公开提供了组合物,其包含与一种或多种粘合剂,悬浮剂或食用酸组合的车前子的提取部分。 特别地,本发明涉及包含以下组分的组合物:(a)包含木糖和阿拉伯糖的多糖组分,其中木糖与阿拉伯糖的比例为至少约3:1重量比; 和(b)选自粘合剂,悬浮剂,食用酸及其混合物的分散组分。 在优选的实施方案中,组合物还包含水性液体,例如水或果汁(例如水果或蔬菜汁)。 因此,本发明还涉及制备产品的方法,包括将本发明组合物与水性液体混合。 本发明的组合物可用于治疗各种益处,包括为胃肠道病症提供治疗或提供其它胃肠道益处。
    • 8. 发明申请
    • COMPOSITIONS COMPRISING A PLURALITY OF PARTICLES OR AGGLOMERATES HAVING A DEFINED PARTICLE SIZE
    • 包含具有确定颗粒尺寸的多种颗粒或聚集体的组合物
    • WO2004073635A2
    • 2004-09-02
    • PCT/US2004004652
    • 2004-02-18
    • PROCTER & GAMBLEMYATT GRAHAM JOHNCIMILUCA PAUL ALFREDGILLISPIE HASANI
    • MYATT GRAHAM JOHNCIMILUCA PAUL ALFREDGILLISPIE HASANI
    • A61K20060101A61K9/00A61K9/16A61K9/68A61K31/715A61K
    • A61K47/36A61K9/0095A61K9/1652A61K47/12Y10S514/884Y10S514/892
    • The present disclosure provides compositions comprising an extracted portion of psyllium seed in combination with one or more of a binder or edible acid. In particular, the present invention is directed to compositions comprising a polysaccharide component comprising xylose and arabinose, wherein the ratio of the xylose to the arabinose is at least about 3 : 1, by weight, and wherein the polysaccharide particles have a mean particle size distribution of from about 0.001 microns to about 150 microns. In a further embodiment, the compositions comprise a plurality of agglomerates comprising the polysaccharide component and a dispersing component selected from binders, suspending agents, edible acids, and mixtures thereof. In yet a further embodiment, the compositions comprise agglomerates comprising a polysaccharide component, wherein the agglomerates have a mean particle size distribution of from about 100 to about 500 microns. The present compositions are useful for the treatment of a variety of benefits, including providing treatment for gastrointestinal conditions or providing other gastrointestinal benefits.
    • 本公开提供了组合物,其包含欧车前籽的提取部分与一种或多种粘合剂或食用酸的组合。 具体而言,本发明涉及包含含有木糖和阿拉伯糖的多糖组分的组合物,其中木糖与阿拉伯糖的重量比为至少约3:1,并且其中多糖颗粒的平均粒度分布 为约0.001微米至约150微米。 在另一个实施方案中,组合物包含多个附聚物,所述附聚物包含多糖组分和选自粘合剂,悬浮剂,食用酸及其混合物的分散组分。 在又一个实施方案中,组合物包含含有多糖组分的附聚物,其中附聚物具有约100至约500微米的平均粒度分布。 本发明组合物可用于治疗各种益处,包括提供胃肠病症治疗或提供其他胃肠益处。