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1. 发明申请

WO2009089395A2 OSTEOINTEGRATION APPARATUS 审中-公开
标题翻译： OSTEOINTEGRATION装置
公开(公告)号：WO2009089395A2
公开(公告)日：2009-07-16
申请号：PCT/US2009/030502
申请日：2009-01-08
申请人： POLARIS BIOTECHNOLOGY, INC. , HENDERSON, Fraser, Cummins, Sr. , HENDERSON, Rebecca, M., S. , NEWMAN, John, W.
发明人： HENDERSON, Fraser, Cummins, Sr. , HENDERSON, Rebecca, M., S. , NEWMAN, John, W.
IPC分类号： A61B17/72 , A61B17/62 , A61B17/58
CPC分类号： A61B17/7055 , A61B17/7011 , A61B17/7043 , A61B17/7044 , A61B17/7049 , A61B17/7052 , A61B17/8061
摘要： A method for effecting reduction, stabilization and enhancement of fusion of the human cranio-cervical junction, which may be performed in order to relieve mechanical stresses imparted to the spinal cord and brainstem as a result of an abnormal clivo-axial angle, includes steps of achieving the correct craniocervical relationship, of effecting a fusion of a first portion of a bone forming material based structural member to a human cranium, and effecting fusion of a second portion of the bone forming material based structural member to a least one portion of a human cervical spine. Fusion of the bone forming material based structural member to the human cranium may be promoted through the use an osteointegration apparatus that includes a porous ossomeric mesh and a frame member.
摘要翻译：包括以下步骤：用于减轻，稳定和增强人类颅颈交界处融合的方法，所述方法可以执行以减轻由于异常的轴向角度而施加给脊髓和脑干的机械应力实现正确的颅颈关系，实现基于骨形成材料的结构构件的第一部分与人颅骨的融合，并且将骨形成材料基结构构件的第二部分熔化到人的至少一部分颈椎。可以通过使用包括多孔骨架网和框架构件的骨整合装置来促进基于骨形成材料的结构构件与人颅骨的融合。

2. 发明申请

WO2011088358A2 CRANIOSPINAL FUSION METHOD AND APPARATUS 审中-公开
标题翻译：电子束融合方法和设备
公开(公告)号：WO2011088358A2
公开(公告)日：2011-07-21
申请号：PCT/US2011/021351
申请日：2011-01-14
申请人： POLARIS BIOTECHNOLOGY, INC. , HENDERSON, Fraser, Cummins, SR. , NEWMAN, John, W.
发明人： HENDERSON, Fraser, Cummins, SR. , NEWMAN, John, W.
CPC分类号： A61B17/7055 , A61B17/7011 , A61B17/7043 , A61B17/7044 , A61B17/7049 , A61B17/7052 , A61B17/8061
摘要： A spinal stabilization system that may be used to fix craniocervical junction. The system includes a cranial spinal attachment system that anchors one or more surgical instruments to a cranial surface using at least one cranial clamp and cranial fastener. The cranial spinal attachment system may be positioned along a perimeter of a cranial defect.
摘要翻译：
一种可用于固定颅颈交界处的脊柱稳定系统。该系统包括颅侧脊柱附接系统，其使用至少一个颅侧夹和颅侧紧固件将一个或多个手术器械锚定到颅侧表面。颅侧脊柱连接系统可以沿颅骨缺损的周边定位。

3. 发明申请

WO2009064536A1 VERTEBRA ATTACHMENT METHOD AND SYSTEM 审中-公开
标题翻译： VERTEBRA附件方法和系统
公开(公告)号：WO2009064536A1
公开(公告)日：2009-05-22
申请号：PCT/US2008/077115
申请日：2008-09-19
申请人： POLARIS BIOTECHNOLOGY, INC. , HENDERSON, Fraser, Cummins, SR. , NEWMAN, John, W.
发明人： HENDERSON, Fraser, Cummins, SR. , NEWMAN, John, W.
IPC分类号： A61B17/70
CPC分类号： A61B17/7056 , A61B17/7011 , A61B17/7047 , A61B17/7049 , A61B17/7052 , A61B17/7055 , A61B17/7062 , A61B17/7082 , A61B17/8605 , A61B17/863 , A61B2017/00004
摘要： A vertebral attachment method and system (100) that minimizes or eliminates the risk of severing, compressing, impinging or otherwise injuring the vertebral artery vertebral vein, spinal nerve roots and/or spinal cord,. The system includes at least one plate (3) that may be anchored to a posterior region of a vertebra using at least one clamp (1) and fastener (2). The system may be specifically designed to retain a portion of the posterior region of the vertebra.
摘要翻译：脊椎附着方法和系统（100），其最小化或消除了切断，压缩，撞击或以其他方式伤害椎动脉脊椎静脉，脊神经根和/或脊髓的风险。该系统包括至少一个板（3），其可以使用至少一个夹具（1）和紧固件（2）锚固到椎骨的后部区域。该系统可以被专门设计成保留椎骨后部区域的一部分。

4. 发明申请

WO2010002409A1 CRANIOSPINAL FUSION METHOD AND APPARATUS 审中-公开
标题翻译： CRANIOSPINAL FUSION方法和装置
公开(公告)号：WO2010002409A1
公开(公告)日：2010-01-07
申请号：PCT/US2008/069036
申请日：2008-07-02
申请人： POLARIS BIOTECHNOLOGY, INC. , HENDERSON, Fraser, Cummins , NEWMAN, John, W.
发明人： HENDERSON, Fraser, Cummins , NEWMAN, John, W.
IPC分类号： A61B17/70
CPC分类号： A61B17/7055 , A61B17/7011 , A61B17/7032 , A61B17/7052 , A61B17/7059
摘要： A method for effecting reduction stabilization and enhancement of fusion of the human cranio-cervical junction, which may be performed in order to relieve mechanical stresses imparted to the spinal cord and brainstem as a result of an abnormal clivo-axial angle, includes steps of achieving the correct craniocervical relationship, of effecting a fusion of a first portion of a bone forming material based structural member (16, 18) to a human cranium, and effecting fusion of a second portion of the bone forming material based structural member (20, 22) to at least one portion of a human cervical spine (C1, C2). Fusion of the bone forming material based structural member (12, 14) to the human cranium may be promoted through the use of plate member (24) that is shaped to define a graft accommodation space (32) between the plate member and the cranium.
摘要翻译：包括以下步骤：实现人颅颈交界处的还原稳定化和增强融合的方法，所述方法可以是为了减轻作为异常轴向角度而导致的对脊髓和脑干施加的机械应力而进行的正确的颅颈关系，使得骨形成材料基结构构件（16,18）的第一部分与人颅骨融合，并且使骨形成材料基结构构件（20,22）的第二部分熔化）到人类颈椎（C1，C2）的至少一部分。可以通过使用成形为在板构件和颅骨之间限定移植物容纳空间（32）的板构件（24）来促进基于骨形成材料的结构构件（12,14）与人颅骨的融合。

5. 发明申请

WO2012003372A3 METHOD AND APPARATUS FOR THE REMOTE NONDESTRUCTIVE EVALUATION OF AN OBJECT 审中-公开
公开(公告)号：WO2012003372A3
公开(公告)日：2012-01-05
申请号：PCT/US2011/042673
申请日：2011-06-30
申请人： NEWMAN, John, W.
发明人： NEWMAN, John, W.
IPC分类号： G01B11/16 , G01L1/24
摘要： A method and apparatus for the remote nondestructive evaluation of an object such as a wind turbine blade involves applying mechanical and/or thermal stress to the object and then scanning the object using long-range thermographic and/or laser interferometric imaging. The laser interferometric imaging is preferably performed by a long range shearography camera capable of imaging deformation derivatives at long distances coupled with a blade stressing mechanism incorporating either thermal or internal blade pressurization for the purpose of detecting remotely and at high speed, changes in the structural integrity of an installed wind turbine blade.

6. 发明申请

WO2014008505A1 METHOD AND SYSTEM FOR MEASURING A PROPERTY OF A NON-NEWTONIAN FLUID 审中-公开
标题翻译：用于测量非牛顿流体的性质的方法和系统
公开(公告)号：WO2014008505A1
公开(公告)日：2014-01-09
申请号：PCT/US2013/049591
申请日：2013-07-08
申请人： NEWMAN, John, W.
发明人： NEWMAN, John, W.
IPC分类号： G01N11/00 , G01N33/42
CPC分类号： G01N11/00 , G01N11/06 , G01N33/26 , G01N33/42 , G01N2203/0044 , G01N2203/0094
摘要： A system and method for measuring the deformation over time of the surface of a non- Newtonian fluid in a sampling container in response to an airjet that is applied for a specified time are disclosed. The change is the sample surface displacement is measured quantitatively by means of optical triangulation or other similar optical or electronic distance measuring device. After cessation of the airjet, gravitational forces cause the sample material to flow back to its original surface profile. Both the amplitude of the deformation displacement due to the force of the airjet and the recovered displacement, within specific time periods are characteristic of asphalt binder material with varying amounts of polymer or other additives used to control the ultimate properties and performance of the material. As a result, comparison of the quantitative measurements of control samples can allow discrimination from samples with different properties and hence different formulations.
摘要翻译：公开了一种用于响应于施加特定时间的空气喷射来测量采样容器中的非牛顿流体的表面随时间的变形的系统和方法。该变化是样品表面位移通过光学三角测量或其他类似的光学或电子距离测量装置定量测量。在喷气停止之后，重力导致样品材料回流到其原始表面轮廓。在特定的时间段内由于喷气推力和回收的位移而引起的变形位移的幅度都是沥青粘合剂材料的特征，其中沥青粘合剂材料具有用于控制材料的最终性能和性能的不同量的聚合物或其他添加剂。因此，比较对照样品的定量测量结果可以区分具有不同性质和不同配方的样品。

7. 发明申请

WO2004089296A2 IMPROVED INHIBITORS FOR THE SOLUBLE EPOXIDE HYDROLASE 审中-公开
标题翻译：改进的可溶性环氧化物水解抑制剂
公开(公告)号：WO2004089296A2
公开(公告)日：2004-10-21
申请号：PCT/US2004/010298
申请日：2004-04-02
申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , HAMMOCK, Bruce, D. , KIM, In-Hae , MORISSEAU, Christophe , WATANABE, Takaho , NEWMAN, John, W.
发明人： HAMMOCK, Bruce, D. , KIM, In-Hae , MORISSEAU, Christophe , WATANABE, Takaho , NEWMAN, John, W.
IPC分类号： A61K
CPC分类号： C07C275/26 , C07C275/30 , C07C275/42 , C07C311/04 , C07C311/05 , C07C311/51 , C07C323/59 , C07C2601/02 , C07C2601/14 , C07C2603/74 , C07D207/16 , C07D233/24 , C07D233/64
摘要： Inhibitors of the soluble epoxide hydrolase (sEH) are provided that incorporate multiple pharmacophores and are useful in the treatment of diseases.
摘要翻译：提供了可溶性环氧化物水解酶（sEH）的抑制剂，其包含多个药效团并且可用于治疗疾病。

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