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1. 发明申请

WO1998006321A1 FORMING AN IMAGE OF A TURBID MEDIUM USING A FLUID TO REDUCE BOUNDARY EFFECTS 审中-公开
标题翻译：使用流体来形成涡轮介质的图像以减少边界效应
公开(公告)号：WO1998006321A1
公开(公告)日：1998-02-19
申请号：PCT/IB1997000955
申请日：1997-07-31
申请人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB
发明人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB , PAPAIOANNOU, Dimitrios , 'T HOOFT, Gert, W. , VAN DER MARK, Martinus, B.
IPC分类号： A61B05/00
CPC分类号： A61B5/0091 , A61B5/4312 , G01N21/4795
摘要： A device for imaging a turbid medium, for example a breast of a female, comprising a holder for comprising the turbid medium, a light source, a photodetector and a processing unit for deriving the image from the intensities measured is adapted to comprise besides the turbid medium also an adaptation medium having substantial identical optical parameters as the optical parameters of the turbid medium. In this way artefacts in the reconstructed image due to the boundary effect between the turbid medium and the holder can be reduced. When a liquid is used as an adaptation medium a perfect match between the holder and the shape of the turbid medium can be obtained. Further, according to the invention also intensity differences in the image due to different path lengths between light source and photodetector could be equalized.
摘要翻译：用于对浑浊介质（例如女性乳房）进行成像的装置，包括用于包括浑浊介质的保持器，光源，光电检测器和用于从测量的强度导出图像的处理单元，除了混浊之外还包括介质也是具有与混浊介质的光学参数大致相同的光学参数的适应介质。以这种方式，可以减少由于混浊介质和保持器之间的边界效应引起的重建图像中的伪像。当液体用作适应介质时，可以获得保持器与混浊介质的形状之间的完美匹配。此外，根据本发明，由于光源和光电检测器之间的不同路径长度的图像中的强度差也可以相等。

2. 发明申请

WO1997023161A3 DEVICE FOR LOCALIZING AN OBJECT IN A TURBID MEDIUM 审中-公开
公开(公告)号：WO1997023161A3
公开(公告)日：1997-07-03
申请号：PCT/IB1996001396
申请日：1996-12-09
申请人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB
发明人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB , PAPAIOANNOU, Dimitrios , 'T HOOFT, Gert, Wim
IPC分类号： A61B05/00

3. 发明申请

WO1996029000A1 DEVICE FOR CARRYING OUT OPTICAL MEASUREMENTS IN TURBID MEDIA 审中-公开
标题翻译：在涡轮介质中进行光学测量的装置
公开(公告)号：WO1996029000A1
公开(公告)日：1996-09-26
申请号：PCT/IB1996000201
申请日：1996-03-11
申请人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB
发明人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB , PAPAIOANNOU, Dimitrios
IPC分类号： A61B05/00
CPC分类号： A61B5/0091 , A61B5/4312
摘要： A device for localizing an object (118) in a turbid medium (111), comprising a laser (100) which is used for generating amplitude-modulated light which is conducted into a turbid media (111), and a detection unit (107) for measuring the amplitude-modulated light emanating from the turbid media. A signal processing unit (109) measures a phase and amplitude from the detector signal (115). It appears that the accuracy of the measured phase is influenced by higher harmonics present in the detector signal (115). The accuracy of the phase detection is improved by reducing the higher harmonics in the detector signal (115). This is achieved by reducing the higher harmonics in the amplitude-modulated light from the laser (100) by utilizing a two-mode laser.
摘要翻译：一种用于将物体（118）定位在混浊介质（111）中的装置，包括用于产生传导到浑浊介质（111）中的调幅光的激光（100）和检测单元（107）用于测量从混浊介质发出的幅度调制光。信号处理单元（109）从检测器信号（115）测量相位和幅度。看来，测量相位的精度受检测器信号（115）中存在的高次谐波的影响。通过降低检测器信号（115）中的高次谐波来提高相位检测的精度。这是通过利用双模激光器来降低来自激光器（100）的调幅光的高次谐波来实现的。

4. 发明申请

WO1996000893A1 DEVICE FOR AND METHOD OF CARRYING OUT OPTICAL MEASUREMENTS IN TURBID MEDIA 审中-公开
标题翻译：在涡轮介质中进行光学测量的装置和方法
公开(公告)号：WO1996000893A1
公开(公告)日：1996-01-11
申请号：PCT/IB1995000485
申请日：1995-06-15
申请人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB
发明人： PHILIPS ELECTRONICS N.V. , PHILIPS NORDEN AB , PAPAIOANNOU, Dimitrios
IPC分类号： G01N21/49
CPC分类号： G01N21/4795
摘要： Device for carrying out optical measurements in turbid media (105), e.g. biological tissue (119), comprising a coherent light source (150), a modulator (101) to modulate the frequency of the light source (150) and a detector (108), being sensitive to a small band of the modulated light frequencies of the light source. Light source (104) and detector (107) are placed opposite each other in a turbid medium (105). Because the behaviour of the transmission of the FM-modulated light in the medium can be described by means of a travelling wave, the detector shows different amplitudes and phases of the FM-modulation as a function of the distance to the light source. From the measured amplitudes and phases characteristics of the turbid medium can be derived. By applying two groups of light sources and the modulation of one group of light sources is in phase opposition within the other group of light sources it is possible to detect objects in the turbid medium. The device offers possibilities as a diagnostic tool for biological tissue, e.g. detection of tumours in mammal tissue.
摘要翻译：用于在混浊介质（105）中进行光学测量的装置，例如生物组织（119），包括相干光源（150），用于调制光源（150）的频率的调制器（101）和检测器（108），对于调制光频率光源。光源（104）和检测器（107）在混浊介质（105）中相对放置。由于可以通过行波来描述FM调制光在介质中传输的行为，所以检测器根据到光源的距离来显示FM调制的不同幅度和相位。可以从测量的混沌介质的振幅和相位特征中得出。通过应用两组光源，并且一组光源的调制在另一组光源内相位相反，可以检测混浊介质中的物体。该装置提供用于生物组织的诊断工具的可能性，例如。检测哺乳动物组织中的肿瘤。

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