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1. 发明申请

WO2008050208A1 TRANSFER LINE 审中-公开
标题翻译：转运线
公开(公告)号：WO2008050208A1
公开(公告)日：2008-05-02
申请号：PCT/IB2007/003157
申请日：2007-10-17
申请人： PFIZER PRODUCTS INC. , VAN GOOLEN, Gunther, Victor, Maria, Emiel , VANQUICKENBORNE, Stefaan, Jaak , HARRISON, Nigel
发明人： VAN GOOLEN, Gunther, Victor, Maria, Emiel , VANQUICKENBORNE, Stefaan, Jaak , HARRISON, Nigel
IPC分类号： A61J3/07
CPC分类号： A61J3/07 , A61J3/072 , A61J3/074 , B65G35/08
摘要： The present invention relates to a transfer line for the transfer of identical filled two-piece capsules between two successive processing stations comprising a and on unloading area, a plurality of identical transfer units each comprising a plurality of cavities each adapted to receive a capsule at the loading area and to let such capsule being unloaded at the unloading area, said plurality of cavities of each transfer unit being designed so as to receive in a first relative configuration the groups of filled two-piece capsules when located at a loading position in the loading area and so as to discharge these groups when located at an unloading position in the unloading area, a conveyor device adapted to temporarily and individually support the transfer units so as to transfer them from the loading position to the unloading position and vice-versa, while keeping them substantially in a same orientation in the loading and unloading positions, and at least from the loading position to the unloading position.
摘要翻译：本发明涉及一种用于在两个连续的处理站之间传送相同的填充的两件式胶囊的传送管线，包括装载区域和卸载区域，多个相同的传送单元，每个传送单元包括多个腔室，每个腔体适于容纳胶囊在所述装载区域处，并且使所述胶囊在所述卸载区域被卸载，所述每个传送单元的所述多个空腔被设计成在第一相对构型中接收所述填充的两件式胶囊组，当位于所述装载位置装载区域，并且当位于卸载区域中的卸载位置时排出这些组;传送装置，其适于临时和单独地支撑传送单元，以便将它们从装载位置传送到卸载位置，反之亦然同时保持它们在装载和卸载位置上基本保持相同的方向，并且至少从装载位置到卸载位置。

2. 发明申请

WO2008015555A2 APPARATUS AND METHOD FOR REMOVING MOLDED ARTICLES FROM THEIR MOLDS 审中-公开
标题翻译：用于从其模具中取出模制制品的设备和方法
公开(公告)号：WO2008015555A2
公开(公告)日：2008-02-07
申请号：PCT/IB2007/002224
申请日：2007-07-27
申请人： PFIZER PRODUCTS INC. , GOOSSENS, Francies, Petrus, Joseph , SURINX, Dominique, Suzanne, François , VANQUICKENBORNE, Stefaan, Jaak
发明人： GOOSSENS, Francies, Petrus, Joseph , SURINX, Dominique, Suzanne, François , VANQUICKENBORNE, Stefaan, Jaak
CPC分类号： B29C37/0003 , B29C31/006 , B29C33/444 , B29C2043/5007 , B29C2043/5069
摘要： The present invention relates to a method and apparatus for removing a plurality of molded articles from respective molds each having an external molding surface oriented according to a mold axis (X), said molds (12) being arranged with their axis (X) parallel. The apparatus comprises a plurality of pairs of jaws (4,6), each corresponding to a respective mold (12) and including a first jaw (4) and an opposed second jaw (6) which are moveable with respect to the respective mold (12) according to a first relative motion, between an open position wherein the jaws (4, 6) are spaced apart from the mold (;12) and a closed position wherein the jaws (4, 6) engage the mold (12), and a substantially axial second relative motion, wherein the pair of jaws (4,6) is slidably displaced along the mold axis (X) so as to remove it from the mold (12), The jaws (4, 6), for the first relative motion, are linearly moveable in parallel directions which are radial to the respective mold axis (X).
摘要翻译：本发明涉及一种用于从各个模具中取出多个模制品的方法和设备，每个模具具有根据模具轴线（X）定向的外部模制表面，所述模具（12）被布置与它们的轴线（X）平行。该装置包括多对夹爪（4,6），每对夹爪对应于相应的模具（12）并且包括可相对于相应的模具移动的第一夹爪（4）和相对的第二夹爪（6）在夹爪（4,6）与模具（12）间隔开的打开位置和夹爪（4,6）与模具（12）接合的闭合位置之间，根据第一相对运动，和基本上轴向的第二相对运动，其中所述一对钳口（4,6）沿着所述模具轴线（X）可滑动地移动，以将其从所述模具（12）中移出。所述钳口（4,6）第一相对运动可以在相应模具轴线（X）的径向的平行方向上线性地移动。

3. 发明申请

WO2008050205A1 CAPSULE FORMATION 审中-公开
标题翻译：胶囊形成
公开(公告)号：WO2008050205A1
公开(公告)日：2008-05-02
申请号：PCT/IB2007/003144
申请日：2007-10-17
申请人： PFIZER PRODUCTS INC. , DE BOCK, Jan, Juilen, Irma , SINNAEVE, Jan, Donaat , VANQUICKENBORNE, Stefaan, Jaak
发明人： DE BOCK, Jan, Juilen, Irma , SINNAEVE, Jan, Donaat , VANQUICKENBORNE, Stefaan, Jaak
IPC分类号： A61J3/07
CPC分类号： B29C35/02 , A61J3/077
摘要： A method and apparatus for forming hard shell capsule components, wherein the capsule components are formed from a material which undergoes gelation upon heating, such as HPMC. A heat station is provided to heat a plurality of molds prior to dipping into a solution of the thermogeling material. The drying conditions following dipping are carefully controlled to control the rate of drying.
摘要翻译：一种用于形成硬壳胶囊组分的方法和装置，其中胶囊组分由加热时经历凝胶化的材料形成，例如HPMC。提供加热站以在浸入热胶材料的溶液之前加热多个模具。仔细控制浸渍后的干燥条件以控制干燥速率。

4. 发明申请

WO2009138920A1 IMPROVED CAPSULE WITH AIR-VENTS 审中-公开
标题翻译：改进的CAPSULE与空气
公开(公告)号：WO2009138920A1
公开(公告)日：2009-11-19
申请号：PCT/IB2009/051880
申请日：2009-05-07
申请人： PFIZER INC. , BUYDTS, Hilde , SINNAEVE, Jan, Donaat , VANQUICKENBORNE, Stefaan, Jaak
发明人： BUYDTS, Hilde , SINNAEVE, Jan, Donaat , VANQUICKENBORNE, Stefaan, Jaak
IPC分类号： A61J3/07
CPC分类号： A61J3/072
摘要： The invention relates to a capsule comprising a hollow tubular body (2), a hollow cap (3) telescopically engageable on the body (2), the body (2) and the cap (3) defining an inner volume therebetween and being provided with complementary snap-fit means (12, 21 ) for locking the cap (3) on the body (2) in the fully closed final position, the complementary snap-fit means (12, 21 ) comprising a locking ring (12) formed on the body (2) and a complementary ridge member (21 ) formed on the cap (3), at least one air-vent (14) formed as an axial recess on the outer surface of the body (2) and suitable for ensuring fluid communication between the inner volume and the atmosphere. The capsule (1 ) is configured such that, in the fully closed final position, the inner surface of the cap (3) fits on the outer surface of the body (2) over a continuous circumferential contact section (33) and the air-vent (14) axially extends from the open end (5) of the body (2) toward the contact section (33), so as to provide fluid communication between the inner volume and the atmosphere over the whole range of engagement positions, excluding the fully closed final position wherein the inner surface of the cap (3) sealingly engages the outer surface of the body (2) over the contact section (33). Application to capsules for liquid dosages.
摘要翻译：本发明涉及一种胶囊，其包括中空管状体（2），可伸缩地接合在主体（2）上的空心帽（3），主体（2）和帽（3）在其间限定内部容积，用于在完全闭合的最终位置中将盖（3）锁定在主体（2）上的互补卡扣配合装置（12,21），所述互补卡扣配合装置（12,21）包括形成在主体（2）和形成在盖（3）上的互补脊部件（21），至少一个形成为主体（2）的外表面上的轴向凹槽的排气口（14），并且适于确保流体内容与气氛之间的沟通。胶囊（1）构造成使得在完全闭合的最终位置中，盖（3）的内表面在连续的圆周接触部分（33）上装配在主体（2）的外表面上，排气口（14）从主体（2）的开口端（5）朝向接触部分（33）轴向延伸，以便在整个接合位置范围内在内部容积和大气之间提供流体连通，不包括完全闭合的最终位置，其中盖（3）的内表面在接触部分（33）上密封地接合主体（2）的外表面。用于液体剂量的胶囊。

5. 发明申请

WO2009027809A2 LIQUID PUMP 审中-公开
标题翻译：液体泵
公开(公告)号：WO2009027809A2
公开(公告)日：2009-03-05
申请号：PCT/IB2008/002250
申请日：2008-08-22
申请人： PFIZER INC. , VAN GOOLEN, Gunther , VANQUICKENBORNE, Stefaan, Jaak
发明人： VAN GOOLEN, Gunther , VANQUICKENBORNE, Stefaan, Jaak
IPC分类号： F04B1/16 , F04B53/10 , F04B53/14
CPC分类号： F04B1/16 , F04B53/10 , F04B53/147 , F05C2203/08
摘要： A liquid pump for dispensing a liquid is provided. The pump comprises a body which defines a plurality of cylinders therein, each cylinder having located therein a respective piston, wherein each cylinder and respective piston is shaped and configured such that the fit between them substantially prevents leakage of the liquid to be dispensed. Such a liquid pump may be used to fill pharmaceutical dosage forms, such as capsules, with liquid pharmaceutical compositions.
摘要翻译：提供了一种用于分配液体的液体泵。该泵包括在其中限定多个缸体的主体，每个缸体中具有相应的活塞，其中每个缸体和相应的活塞被成形和构造成使得它们之间的配合基本上防止待分配的液体泄漏。这种液体泵可用于用液体药物组合物填充药物剂型，例如胶囊剂。

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