专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2013164754A2 PROSTATE-ASSOCIATED ANTIGENS AND VACCINE-BASED IMMUNOTHERAPY REGIMENS 审中-公开
标题翻译： PROSTATE相关抗原和基于疫苗的免疫治疗方案
公开(公告)号：WO2013164754A2
公开(公告)日：2013-11-07
申请号：PCT/IB2013/053377
申请日：2013-04-29
申请人： PFIZER INC.
发明人： BINDER, Joseph John , CHO, Helen Kim , DERMYER, Michael Robert , JOOSS, Karin Ute , PIERCE, Brian Gregory , TAN, Joyce Tsi , TSAI, Van To
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K9/0019 , A61K31/404 , A61K31/7088 , A61K39/39 , A61K39/3955 , A61K2039/53 , A61K2039/55561 , C07K14/4748 , C07K16/2818 , C07K16/3023 , C07K16/303 , C07K16/3069 , C07K2317/21 , C07K2317/76 , C12N9/485 , C12N9/6445 , C12Y304/17021
摘要： The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.
摘要翻译：本公开内容提供（a）分离的免疫原性PAA多肽; （b）编码免疫原性PAA多肽的分离的核酸分子; （c）包含免疫原性PAA多肽或编码免疫原性PAA多肽的分离的核酸分子的疫苗组合物; （d）与多肽，核酸分子和组合物的用途有关的方法; 和（e）基于疫苗的免疫治疗方案，其涉及将疫苗与免疫抑制细胞抑制剂和免疫效应细胞增强剂组合共同给药。

2. 发明申请

WO2011154863A1 HER-2 PEPTIDES AND VACCINES 审中-公开
标题翻译： HER-2肽和疫苗
公开(公告)号：WO2011154863A1
公开(公告)日：2011-12-15
申请号：PCT/IB2011/052246
申请日：2011-05-23
申请人： PFIZER INC. , CHO, Helen Kim , GURU, Siradanahalli Chandrasekharaiah , TSAI, Van To , PIERCE, Brian Gregory
发明人： CHO, Helen Kim , GURU, Siradanahalli Chandrasekharaiah , TSAI, Van To , PIERCE, Brian Gregory
IPC分类号： C07K14/71 , C07K14/82 , A61K39/00 , A61P35/00
CPC分类号： C07K14/71 , A61K39/0011 , A61K2039/53 , C07K14/82
摘要： The present invention provides (a) isolated immunogenic HER-2 peptides capable of inducing immune responses against human HER-2 receptor; (b) isolated nucleic acid molecules encoding an isolated immunogenic HER-2 peptide; (c ) plasmid constructs comprising a nucleic acid molecule encoding an isolated immunogenic HER- 2 peptide; (d) vaccine compositions comprising an isolated immunogenic HER-2 peptide (e) vaccine compositions comprising an isolated nucleic acid molecule encoding an isolated immunogenic HER-2 peptide; and (f) methods of treating or preventing cancer, inhibiting abnormal cell proliferation, or eliciting an immune response against HER-2 protein in a mammal using (1 ) an isolated immunogenic HER-2 peptide, (2) nucleic acid molecule encoding an isolated immunogenic HER-2 peptide, or (3) a composition comprising an isolated immunogenic HER-2 peptide, or composition comprising a nucleic acid molecule encoding an isolated immunogenic HER-2 peptide.
摘要翻译：本发明提供（a）能够诱导针对人HER-2受体的免疫应答的分离的免疫原性HER-2肽; （b）编码分离的免疫原性HER-2肽的分离的核酸分子; （c）包含编码分离的免疫原性HER-2肽的核酸分子的质粒构建体; （d）包含分离的免疫原性HER-2肽（e）疫苗组合物的疫苗组合物，其包含编码分离的免疫原性HER-2肽的分离的核酸分子; 和（f）使用（1）分离的免疫原性HER-2肽，（2）编码分离的免疫原性HER-2肽的核酸分子来治疗或预防癌症，抑制异常细胞增殖或引起哺乳动物中对HER-2蛋白的免疫应答的方法免疫原性HER-2肽，或（3）包含分离的免疫原性HER-2肽或包含编码分离的免疫原性HER-2肽的核酸分子的组合物的组合物。

3. 发明申请

WO2017125844A1 CANCER VACCINES 审中-公开
标题翻译：癌症疫苗
公开(公告)号：WO2017125844A1
公开(公告)日：2017-07-27
申请号：PCT/IB2017/050229
申请日：2017-01-16
申请人： PFIZER INC.
发明人： BINDER, Joseph John , CHO, Helen Kim , COCKLE, Paul Jason , FALCONER, Derek John , GURU, Siradanahalli , JOOSS, Karin Ute , MARTINIC, Marianne Marcela Andrea , WILLS, Kenneth Nelson
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K2039/53 , A61K2039/57 , A61K2039/575 , A61K2039/585 , A61K2039/70
摘要： The present disclosure provides (a) isolated immunogenic TAA polypeptides (i.e., an immunogenic MUC1 polypeptides, an immunogenic MSLN polypeptides, and an immunogenic TERT polypeptides), (b) isolated nucleic acid molecules encoding one or more immunogenic TAA polypeptides, (c) vaccine compositions comprising an immunogenic TAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic TAA polypeptide, and (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions.
摘要翻译：（a）分离的免疫原性TAA多肽（即免疫原性MUC1多肽，免疫原性MSLN多肽和免疫原性TERT多肽），（b）分离的核酸分子，其编码一个或多个（c）包含免疫原性TAA多肽或编码免疫原性TAA多肽的分离的核酸分子的疫苗组合物，以及（d）涉及所述多肽，核酸分子和组合物的用途的方法。

4. 发明申请

WO2019012371A1 IMMUNOGENIC COMPOSITIONS COMPRISING CEA MUC1 AND TERT 审中-公开
公开(公告)号：WO2019012371A1
公开(公告)日：2019-01-17
申请号：PCT/IB2018/054926
申请日：2018-07-03
申请人： PFIZER INC.
发明人： BINDER, Joseph John , CHO, Helen Kim , COCKLE, Paul Jason , FALCONER, Derek John , GURU, Siradanahalli , MARTINIC, Marianne Marcela Andrea
IPC分类号： A61K39/00 , C12N7/00
摘要： The present disclosure provides: (a) isolated immunogenic CEA polypeptides; (b) isolated nucleic acid molecules encoding (i) an immunogenic CEA polypeptide, (ii) an immunogenic CEA polypeptide and an immunogenic MUC1 polypeptide, (iii) an immunogenic CEA polypeptide and an immunogenic TERT polypeptide, or (iv) an immunogenic CEA polypeptide, an immunogenic MUC1 polypeptide, and an immunogenic TERT polypeptide; (c) compositions comprising an isolated nucleic acid molecule; and (d) methods relating to uses of the immunogenic CEA polypeptides, nucleic acid molecules, and compositions.

5. 发明申请

WO2015063647A1 VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS 审中-公开
标题翻译：前列腺相关抗原表达载体
公开(公告)号：WO2015063647A1
公开(公告)日：2015-05-07
申请号：PCT/IB2014/065419
申请日：2014-10-17
申请人： PFIZER INC.
发明人： BINDER, Joseph John , CHO, Helen Kim
IPC分类号： A61K39/00
CPC分类号： A61K39/0011 , A61K31/404 , A61K31/436 , A61K31/44 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/7088 , A61K39/00 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/53 , A61K2039/55516 , A61K2039/55561 , A61K2039/645 , A61K2039/70 , C07K14/705 , C07K16/2818 , C07K16/2878 , C07K2317/75 , C07K2319/40 , C12N7/00 , C12N9/6424 , C12N2710/10343 , C12N2710/10371 , C12N2830/006 , C12N2840/20 , C12N2840/203 , C12Y304/21077 , A61K2300/00
摘要： The present disclosure provides (a) vectors comprising a multi-antigen construct encoding two, three, or more immunogenic PAA polypeptides; (b) compositions comprising the vectors, (c) methods relating to uses of the vectors and compositions for eliciting an immune response or for treating prostate cancers.
摘要翻译：本公开提供（a）载体，其包含编码两种，三种或更多种免疫原性PAA多肽的多抗原构建体; （b）包含载体的组合物，（c）与用于引发免疫应答或用于治疗前列腺癌的载体和组合物的用途有关的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式