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1. 发明申请

WO2007016673A2 TOTAL ARTIFICIAL DISC 审中-公开
标题翻译：总人造盘
公开(公告)号：WO2007016673A2
公开(公告)日：2007-02-08
申请号：PCT/US2006030267
申请日：2006-08-02
申请人： PERUMALA CORP , PISHARODI MADHAVAN
发明人： PISHARODI MADHAVAN
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/3094 , A61F2/441 , A61F2002/30069 , A61F2002/30075 , A61F2002/30331 , A61F2002/30426 , A61F2002/30546 , A61F2002/30563 , A61F2002/30566 , A61F2002/30571 , A61F2002/30578 , A61F2002/30579 , A61F2002/30581 , A61F2002/30601 , A61F2002/3067 , A61F2002/30795 , A61F2002/30841 , A61F2002/449 , A61F2002/4495 , A61F2002/482 , A61F2210/0061 , A61F2220/0025 , A61F2220/0033 , A61F2250/0002 , A61F2250/0012 , A61F2310/00011 , A61F2310/00023 , A61F2310/00029 , A61F2310/00161 , A61F2310/00407 , A61F2310/00796
摘要： An artificial disc prosthesis having load-bearing characteristics that mimic those of the normal, healthy intervertebral disc so as to provide resist flexion and axial compression of the spine in a way that preserves normal spinal function. The disc prosthesis includes three main components, a frame, a cushion molded over the frame, and a sac containing a hydrogel for maintaining disc height that is confined within a cavity in the cushion. Disc height is changed by increasing and/or decreasing the amount of hydrogel in the sac in accordance with the particular needs of the patient into which the artificial disc is implanted. Also provided is a frame for an artificial intervertebral disc that allows the axis of rotation of the spine to shift in a manner that replicates, or mimics, the normal function of the intervertebral disc.
摘要翻译：具有模拟正常健康椎间盘的承载特性的人造椎间盘假体，以便以保持正常脊柱功能的方式提供脊柱的抵抗屈曲和轴向压缩。椎间盘假体包括三个主要部件，框架，模制在框架上的衬垫，以及包含水凝胶的囊，用于保持限制在衬垫中的空腔内的盘高度。通过根据植入人造椎间盘的患者的特定需要增加和/或减少囊中的水凝胶的量来改变椎间盘的高度。还提供了一种用于人造椎间盘的框架，其允许脊柱的旋转轴线以复制或模拟椎间盘的正常功能的方式移动。

2. 发明申请

WO0018312B1 MULTI-AXIS CONNECTIONS BETWEEN SPINAL STABILIZERS AND SCREWS 审中-公开
标题翻译：脊柱稳定器和螺钉之间的多轴连接
公开(公告)号：WO0018312B1
公开(公告)日：2000-06-02
申请号：PCT/US9922232
申请日：1999-09-24
申请人： PERUMALA CORP , PISHARODI MADHAVAN
发明人： PISHARODI MADHAVAN
IPC分类号： A61B17/70 , A61B17/86
CPC分类号： A61B17/7043 , A61B17/7011 , A61B17/7041 , A61B17/7058 , A61B17/8695
摘要： A multi-axis correction washer for use with a spinal stabilizer for internal spinal fixation. The bodies of the washer are provided in cylindrical and wedge-shaped cylindrical configurations with a passage in the center of the longitudinal axis of the cylinder and/or offset from the center axis of the cylindrical washer and a shoulder or other structure for rotatably engaging a hole in a spinal implant. The spinal implant can be a plate and screw-type, ladder-type, or monorail-type spinal fixation system. The washer is rotated to provide an infinite range of angles and screw placements relative to the central axis of the spinal column for maximum flexibility of installation and to effectively transfer the load on the spinal column to the implant, all while maintaining an angle of approximately 90 DEG between the head of the screw and/or nut and the washer which engages the implant.
摘要翻译：用于内部脊柱固定的脊柱稳定器的多轴校正垫圈。垫圈的主体设置成圆柱形和楔形圆柱形构造，其具有在圆柱体的纵向轴线的中心和/或从圆柱形垫圈的中心轴线偏移的通道以及肩部或其他结构，用于可旋转地接合在脊柱植入物的孔。脊柱种植体可以是板式和螺旋式，阶梯式或单轨式脊柱固定系统。旋转垫圈以提供相对于脊柱的中心轴线的无限范围的角度和螺钉放置，以实现最大的安装灵活性并且有效地将脊柱上的负载转移到植入物，同时保持约90°的角度 DEG位于螺钉头部和/或螺母与接合植入物的垫圈之间。

3. 发明申请

WO0182844A3 ROTATING, LOCKING INTERVERTEBRAL DISK STABILIZER 审中-公开
标题翻译：旋转，锁定椎间盘稳定器
公开(公告)号：WO0182844A3
公开(公告)日：2002-04-11
申请号：PCT/US0113824
申请日：2001-04-30
申请人： PERUMALA CORP , PISHARODI MADHAVAN
发明人： PISHARODI MADHAVAN
IPC分类号： A61F2/00 , A61F2/02 , A61F2/28 , A61F2/30 , A61F2/44 , A61F2/46
CPC分类号： A61F2/4611 , A61F2/28 , A61F2/3094 , A61F2/442 , A61F2/4455 , A61F2002/2825 , A61F2002/2839 , A61F2002/30057 , A61F2002/30507 , A61F2002/30538 , A61F2002/30594 , A61F2002/30904 , A61F2002/4649 , A61F2220/0025 , A61F2250/0006
摘要： A middle expanded, removable disk implant for stabilizing adjacent vertebrae. The implant is substantially rectangular in cross-sectional shape with a minimal height and a width greater than the height. The implant is detachably mounted to an applicator for insertion into the space between two adjacent vertebrae from which a portion of the intervertebral disk has been removed. Once inserted, the implant is positioned by anterior-posterior movement in the disk space to the position in which both the expanded, larger width middle portion and the smaller end portions engage the bodies of the adjacent vertebrae and the implant is then rotated to bring the sides of the rectangularly-shaped implant defining the width of the implant, with its larger dimension, into engagement with the bodies of the vertebrae. A locking piece is then inserted into the disk space adjacent the rotated implant. The locking piece includes a surface for bearing against the bodies of the adjacent vertebrae to resist rotation of the locking piece along the longitudinal axis thereof and an implant bearing surface for engaging one of the sides of the implant defining the width of the implant to resist rotation of the implant relative to the locking piece. Both implant and locking piece are comprised of bone, the locking piece being preferably comprised of both cortical and cancellous bone, or the implant is comprised of metal, bio-compatible polymer, or other suitable material. The implant may also include a flared end for maintaining proper spinal curvature of the patient.
摘要翻译：用于稳定相邻椎骨的中间扩展的可移动盘植入物。植入物具有基本上矩形的横截面形状，具有最小的高度和宽度大于高度。植入物可拆卸地安装到施用器上，以插入两个相邻椎骨之间的空间中，椎间盘的一部分从该植入物移除。一旦插入，通过椎间盘内的前后运动将植入物定位到膨胀的较大宽度中间部分和较小端部部分与相邻椎骨的主体接合的位置，然后旋转植入物以使矩形植入物的侧面限定植入物的宽度，其较大的尺寸与椎骨的主体接合。然后将锁定件插入与旋转的植入物相邻的盘片空间中。锁定件包括用于抵靠相邻椎骨的主体的表面，以抵抗锁定片沿着其纵向轴线的旋转;以及植入物支承表面，用于接合限定植入物宽度的植入物的侧面中的一个以抵抗旋转的植入物相对于锁定片。植入物和锁定片都由骨组成，锁定片优选由皮质和松质骨组成，或者植入物由金属，生物相容性聚合物或其它合适的材料组成。植入物还可以包括用于维持患者适当脊柱弯曲的扩张端。

4. 发明申请

WO9640016A3 INTERVERTEBRAL DISK STABILIZER AND INSTRUMENT FOR REDUCTION OF SPONDYLOLISTHESIS 审中-公开
标题翻译：椎间盘稳定器和减少螺旋体的仪器
公开(公告)号：WO9640016A3
公开(公告)日：1997-02-13
申请号：PCT/US9609114
申请日：1996-06-06
申请人： PISHARODI MADHAVAN
发明人： PISHARODI MADHAVAN
IPC分类号： A61F2/44 , A61B17/02 , A61B17/58 , A61B17/70 , A61F2/00 , A61F2/28 , A61F2/30 , A61F2/46
CPC分类号： A61F2/446 , A61B17/025 , A61B2017/0256 , A61F2/30965 , A61F2/442 , A61F2/4611 , A61F2002/2835 , A61F2002/30169 , A61F2002/30214 , A61F2002/30224 , A61F2002/30253 , A61F2002/30286 , A61F2002/3037 , A61F2002/30398 , A61F2002/30405 , A61F2002/30426 , A61F2002/30433 , A61F2002/30434 , A61F2002/30553 , A61F2002/30579 , A61F2002/30594 , A61F2002/30777 , A61F2002/30797 , A61F2002/3085 , A61F2002/30874 , A61F2002/30879 , A61F2002/4475 , A61F2002/4623 , A61F2002/4627 , A61F2002/4629 , A61F2220/0025 , A61F2220/0033 , A61F2220/0041 , A61F2230/0047 , A61F2230/0063 , A61F2230/0067 , A61F2230/0069 , A61F2230/0076 , A61F2250/0008 , A61F2310/00023
摘要： A middle expanded, removable disk implant (22) with substantially rectangular cross-sectional shape with a minimal height (H) and a width (W) greater than the height which is detachably mounted to an applicator (52) for insertion into the anatomical region between two adjacent vertebrae (16, 18) from which a portion of the intervertebral disk has been removed. The implant is positioned by anterior-posterior movement in the disk space to the position in which both the expanded middle portion and the smaller diameter end (25, 36) portions of the implant engage the bodies (12, 14) of the adjacent vertebrae and then rotated to bring the sides (34) of the implant defining the height of the implant into engagement with the bodies of the adjacent vertebrae. A lock (24) is then secured to the implant to prevent further rotation thereof. In the event the adjacent vertebrae need to be aligned before fusion, an elongate implant (112) is provided which is split longitudinally into side-by-side members (113, 114) movable relative to each other and which is inserted into the disk space between two misaligned vertebrae (133, 137). The members are provided with teeth (138) for engaging the adjacent vertebrae and the implant formed by the two side-by-side members is rectangularly-shaped in cross section, the height (H6) of the rectangularly-shaped cross section being less than the width (W6) so that the implant can be inserted between the adjacent vertebrae with the lesser, height dimension oriented in the same direction as the axis of the spinal column and the larger width dimension at approximately a right angle to that axis. One member is then moved relative to the other from the first side-by-side position along the longitudinal axis of the implant to a second position in which the members are aligned with the respective, adjacent, misaligned vertebrae and the implant is rotated 90° to engage the teeth to the bodies of the adjacent vertebrae. The two members are then brought back into the first side-by-side position to draw the vertebrae into alignment and the implant is rotated approximately 90° to disengage the teeth from the vertebrae for removal from the disk space.

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