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1. 发明申请

WO2013011094A4 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES 审中-公开
标题翻译：包含含有羟基和醚官能度的特定极性基团的美菁衍生物的化妆品和/或皮肤病学组合物
公开(公告)号：WO2013011094A4
公开(公告)日：2013-07-11
申请号：PCT/EP2012064195
申请日：2012-07-19
申请人： OREAL , RICHARD HERVE , MARAT XAVIER , L ALLORET FLORENCE , CANDAU DIDIER , SONGEUR-GENEY JULIE , GRUMELARD JULIE , WINKLER BARBARA , HUGLIN DIETMAR
发明人： RICHARD HERVE , MARAT XAVIER , L ALLORET FLORENCE , CANDAU DIDIER , SONGEUR-GENEY JULIE , GRUMELARD JULIE , WINKLER BARBARA , HUGLIN DIETMAR
IPC分类号： A61K8/41 , A61K8/42 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/44 , A61K8/347 , A61K8/41 , A61K8/42 , A61K8/49 , A61K8/4926 , A61K8/4973 , A61Q17/04
摘要： The present invention relates to a cosmetic and/or dermatologigal composition comprising in a physiologically acceptable medium at least one merocyanine derivative of formula (1) or (2) and/or its E,E-, E,Z- or Z,Z-geometrical isomer forms: comprising specific polar groups consisting of hydroxyl- and ether-functionalities. Another object of the present invention relates to a cosmetic process for controlling and/or improving the darkening of the skin under exposure to UV radiation and the homogeneity of the colour of the complexion which comprises the application onto the skin of a cosmetic composition as above defined. Another object of the present invention relates to a cosmetic process for protecting the keratinic materials and particularly the skin against photo-ageing which comprises the application onto the keratinic material of a cosmetic composition as above defined.
摘要翻译：（1）或（2）的部花青衍生物和/或其E，E-，E，Z-或Z，Z- 几何异构体形式：包含由羟基官能团和醚官能团组成的特定极性基团。本发明的另一个目的涉及一种用于在暴露于UV辐射下控制和/或改善皮肤变黑的化妆方法和该肤色的均匀性，该方法包括将上述定义的化妆品组合物施用到皮肤上。本发明的另一个目的涉及一种用于保护角蛋白材料特别是皮肤免受光老化的美容方法，其包括将如上所定义的化妆品组合物施用到角蛋白材料上。

2. 发明申请

WO2013011094A3 COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES 审中-公开
标题翻译：含有包含羟基和其他功能的特定极性基团的梅毒衍生物的化妆和/或皮肤组合物
公开(公告)号：WO2013011094A3
公开(公告)日：2013-06-06
申请号：PCT/EP2012064195
申请日：2012-07-19
申请人： OREAL , RICHARD HERVE , MARAT XAVIER , L ALLORET FLORENCE , CANDAU DIDIER , SONGEUR-GENEY JULIE , GRUMELARD JULIE , WINKLER BARBARA , HUGLIN DIETMAR
发明人： RICHARD HERVE , MARAT XAVIER , L ALLORET FLORENCE , CANDAU DIDIER , SONGEUR-GENEY JULIE , GRUMELARD JULIE , WINKLER BARBARA , HUGLIN DIETMAR
IPC分类号： A61K8/41 , A61K8/42 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/44 , A61K8/347 , A61K8/41 , A61K8/42 , A61K8/49 , A61K8/4926 , A61K8/4973 , A61Q17/04
摘要： The present invention relates to a cosmetic and/or dermatologigal composition comprising in a physiologically acceptable medium at least one merocyanine derivative of formula (1) or (2) and/or its E,E-, E,Z- or Z,Z-geometrical isomer forms: comprising specific polar groups consisting of hydroxyl- and ether-functionalities. Another object of the present invention relates to a cosmetic process for controlling and/or improving the darkening of the skin under exposure to UV radiation and the homogeneity of the colour of the complexion which comprises the application onto the skin of a cosmetic composition as above defined. Another object of the present invention relates to a cosmetic process for protecting the keratinic materials and particularly the skin against photo-ageing which comprises the application onto the keratinic material of a cosmetic composition as above defined.
摘要翻译：本发明涉及化妆品和/或皮肤病学组合物，其包含在生理学上可接受的培养基中，至少一种式（1）或（2）的部花青衍生物和/或其E，E-，E，Z-或Z，Z- 几何异构体形式：包括由羟基和醚官能团组成的特定极性基团。本发明的另一个目的涉及一种用于控制和/或改善在暴露于紫外线辐射下的皮肤变暗的化妆方法和肤色的均匀性，其包括如上所述在化妆品组合物的皮肤上施用。本发明的另一个目的涉及一种用于保护角质化材料，特别是皮肤抵抗光老化的美容方法，其包括将上述应用于上述化妆品组合物的角蛋白材料。

3. 发明申请

WO2009068469A3 GRINDING AIDS FOR MICRONIZED ORGANIC UV ABSORBERS 审中-公开
标题翻译：研磨艾滋病微生物有机紫外线吸收剂
公开(公告)号：WO2009068469A3
公开(公告)日：2009-07-16
申请号：PCT/EP2008065916
申请日：2008-11-20
申请人： CIBA HOLDING INC , MONGIAT SEBASTIEN , GRUMELARD JULIE , EHLIS THOMAS
发明人： MONGIAT SEBASTIEN , GRUMELARD JULIE , EHLIS THOMAS
IPC分类号： A61K8/35 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/411 , A61K8/0241 , A61K8/494 , A61K8/496 , A61K8/4966 , A61K2800/412 , A61Q17/04
摘要： A method of preparing a composition, comprising (a) a micronised insoluble organic UV absorber, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus, in the presence of a grinding aid selected from the groups (b1) carboxylic acids and their salts; (b2) fatty acid esters (b3) alkyl phosphates or phosphoric acid esters; (b4) ethoxylated carboxylic acids or polyethyleneglycol (PEG) esters; (b5) fatty alcohol polyethyleneglycol (PEG) ethers of fatty alcohols; (b6) polyethylene/polypropylene -glycol ethers of saturated or unsaturated C4 - C28 fatty acids; (b7) ethoxylated alkylphenols or ethoxylated alkylphenyl ethers; (b8) esters of polyol and mono-, di- or tri-glycerides; (b9) esters of fatty acids and saccharose; (b10) sorbitan mono- and di-esters of saturated and/or unsaturated C6 - C22 fatty acids and ethylene oxide groups; and (b11) surfactants which are mainly acting as detergent or cleansing agents.
摘要翻译：一种制备组合物的方法，该方法包括（a）微粉化的不溶性有机紫外线吸收剂，该方法包括在研磨装置中，在选自以下的研磨助剂存在下以粗颗粒形式研磨不溶性有机紫外线吸收剂： b1）羧酸及其盐; （b2）脂肪酸酯（b3）烷基磷酸酯或磷酸酯; （b4）乙氧基化羧酸或聚乙二醇（PEG）酯; （b5）脂肪醇的脂肪醇聚乙二醇（PEG）醚; （b6）饱和或不饱和C 4 -C 28脂肪酸的聚乙烯/聚丙二醇醚; （b7）乙氧基化烷基酚或乙氧基化烷基苯基醚; （b8）多元醇与甘油单酯，甘油二酯或甘油三酯的酯; （b9）脂肪酸和蔗糖的酯; （b10）饱和和/或不饱和C6-C22脂肪酸和环氧乙烷基团的脱水山梨糖醇单酯和二酯; 和（b11）主要用作清洁剂或清洁剂的表面活性剂。

4. 发明申请

WO2010091963A3 STABILIZATION OF COSMETIC COMPOSITIONS 审中-公开
标题翻译：化妆品组合物的稳定性
公开(公告)号：WO2010091963A3
公开(公告)日：2013-05-02
申请号：PCT/EP2010051011
申请日：2010-01-28
申请人： BASF SE , HERZOG BERND , GRUMELARD JULIE
发明人： HERZOG BERND , GRUMELARD JULIE
IPC分类号： A61K8/35 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/494 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/411 , A61K8/496 , A61K8/4966 , A61K2800/52 , A61K2800/592 , A61Q17/04
摘要： Disclosed is the Use of UV absorbers selected from (a1) diphenylacrylates; and (a2) specific hydroxyphenyl triazines for stabilizing cosmetic compositions comprising an organic UV absorber selected from (b1) a specific benzophenone derivative, (b2) a specific benzotriazole derivative and (b3) a specific triazine derivative and UV filters selected from (c1) cinnamic acid derivatives; and (c2) dibenzoylmethane derivatives.
摘要翻译：公开了使用选自（a1）二苯基丙烯酸酯的UV吸收剂; 和（a2）用于稳定化妆品组合物的特定羟基苯基三嗪，其包含选自（b1）特定二苯甲酮衍生物，（b2）特定苯并三唑衍生物和（b3）特定三嗪衍生物的有机UV吸收剂和选自（c1）肉桂酸酸衍生物; 和（c2）二苯甲酰甲烷衍生物。

5. 发明申请

WO2008107347A3 USE OF AMINES AND AMIDES FOR THE STABILIZATION OF ORGANIC MICRONIZED UV ABSORBERS 审中-公开
标题翻译：用于有机微波紫外线吸收剂稳定化的氨基和氨基酸的使用
公开(公告)号：WO2008107347A3
公开(公告)日：2009-05-07
申请号：PCT/EP2008052336
申请日：2008-02-27
申请人： CIBA HOLDING INC , DESHAYES CYRILLE , EHLIS THOMAS , GRUMELARD JULIE
发明人： DESHAYES CYRILLE , EHLIS THOMAS , GRUMELARD JULIE
IPC分类号： A61K8/04 , A61K8/35 , A61K8/41 , A61K8/42 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/41 , A61K8/35 , A61K8/494 , A61K2800/52 , A61Q17/04
摘要： Disclosed is the use of amines and amides for the stabilization of a cosmetic composition comprising: (a) an organic micronized UV absorber selected from a benzophenone derivative and (b) a dibenzoylmethane derivative. The use of the amines and amides results in the stabilization of the end-product formulations.
摘要翻译：公开了胺和酰胺用于稳定化妆品组合物的用途，包括：（a）选自二苯甲酮衍生物和（b）二苯甲酰甲烷衍生物的有机微粉化UV吸收剂。使用胺和酰胺导致最终产品配方的稳定化。

6. 发明申请

WO2008135421A3 CRYSTAL MODIFICATIONS OF TRANSMISSION DYES 审中-公开
标题翻译：传染性染色体的晶体修饰
公开(公告)号：WO2008135421A3
公开(公告)日：2009-03-05
申请号：PCT/EP2008055139
申请日：2008-04-28
申请人： CIBA HOLDING INC , VOGT MARTIN , MUELLER STEFAN , GRUMELARD JULIE , DESHAYES CYRILLE , PAUL HOLGER , HAASE JUERG , EHLIS THOMAS
发明人： VOGT MARTIN , MUELLER STEFAN , GRUMELARD JULIE , DESHAYES CYRILLE , PAUL HOLGER , HAASE JUERG , EHLIS THOMAS
IPC分类号： A61K8/49 , A61Q17/04 , A61Q19/08
CPC分类号： C07D295/192 , A61K8/04 , A61K8/494 , A61K31/495 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： Disclosed is the use of an aqueous dispersion comprising (a) a micronized sparingly soluble organic benzophenone derivative of formula (1), selected from the crystal modifications (B) and (C), wherein the crystal modification (B) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.70 Å; and wherein the crystal modification (C) is characterized by a peak in the X-ray diffraction pattern at a d-spacing of about 7.06 Å; and (b) a dispersing agent selected from anionic, non-ionic and amphoteric surfactants; for protecting the human skin from browning and skin aging. The new crystal modification (C) represents a thermodynamically stable compound of formula (1) at 25°C. This modification is therefore suitable in dispersions comprising micro-fine particles.
摘要翻译：公开了含有（a）选自晶体改性（B）和（C）的式（1）的微粉化的微溶有机二苯甲酮衍生物的水性分散体的用途，其中所述晶体改性（B）的特征在于峰在X射线衍射图中，d-间距约为7.70; 并且其中所述晶体改性（C）的特征在于在约7.06的d间距处的X射线衍射图中的峰; 和（b）选自阴离子，非离子和两性表面活性剂的分散剂; 用于保护人体皮肤免受褐变和皮肤老化。新的结晶改性（C）在25℃下代表热力学稳定的式（1）化合物。因此，该修饰适用于包含微细颗粒的分散体。

7. 发明申请

WO2011003774A3 UV FILTER COMBINATIONS COMPRISING BENZYLIDENE MALONATES 审中-公开
标题翻译：包含苯甲酸二甲酯的UV过滤器组合
公开(公告)号：WO2011003774A3
公开(公告)日：2011-04-21
申请号：PCT/EP2010059181
申请日：2010-06-29
申请人： BASF SE , GRUMELARD JULIE , EHLIS THOMAS , HANSCH MARKUS , SOHN MYRIAM
发明人： GRUMELARD JULIE , EHLIS THOMAS , HANSCH MARKUS , SOHN MYRIAM
IPC分类号： A61K8/29 , A61K8/35 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/49 , A61K8/58 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/37
摘要： Disclosed is the use of a UV filter combination, comprising (a) a first UV filter selected from benzylidene malonates of formula (1), wherein R1 methyl; ethyl; propyl; or n-butyl; if R1 is methyl, then R is tert. butyl; formula (II); formula (III); a radical of formula (1a); or a radical of formula (1b); wherein R2 and R3, independently from each other are hydrogen; or methyl; R4 is methyl; ethyl; or n-propyl; R5 and R6 independently from each other are hydrogen; or C1-C3alkyl; if R1 is ethyl; propyl; or n-butyl, then R is isopropyl; and (b) a second UV filter selected from (b1) Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine; (b2) Butyl Methoxydibenzoylmethane; (b3)Diethylhexyl Butamido Triazone; (b4) Ethylhexyl Triazone; (b5) Diethylamino Hydroxy Benzoyl Hexyl Benzoate; (b6) Ethylhexyl Methoxycinnamate; (b7) Ethylhexyl Salicylate; (b8) Homosalate; (b9) Octocrylene; (b10) micronized Methylene Bis-Benzotriazolyl Tetramethylbutylphenol; (b11) Phenylbenzimidazole Sulfonic Acid; (b12) Titanium Dioxide; (b13) micronized Tris-Biphenyl Triazine; and (b14) micronized (2-{4-[2-(4-Diethylamino-2-hydroxy-benzoyl)-benzoyl]-piperazine-1-carbonyl}-phenyl)-(4-diethylamino-2-hydroxy-phenyl)-methanone; (b15) benzoicacid,4,4-[[3-[1,3,3,3-tetramethyl-1-[trimethylsilyl)oxy]-1-disiloxanyl]propyl]amino]-1,3,5-triazine-2,4-diyl]diimino]bis-, dibutyl ester wherein the UV filter combination comprises at least 2 UV filters of component (b1)-(b14); for the protection of human and animal hair and skin against UV radiation.
摘要翻译：公开了UV过滤剂组合的用途，其包含（a）选自式（1）的亚甲基丙二酸酯的第一UV过滤剂，其中R 1甲基; 乙基; 丙基; 或正丁基; 如果R1是甲基，则R是叔。丁基; 公式（II）; 公式（III）; 式（1a）的基团; 或式（1b）的基团; 其中R 2和R 3彼此独立地为氢; 或甲基; R4是甲基; 乙基; 或正丙基; R5和R6彼此独立地为氢; 或C 1 -C 3烷基; 如果R1是乙基; 丙基; 或正丁基，则R是异丙基; 和（b）选自（b1）双 - 乙基己氧基苯酚甲氧基苯基三嗪的第二UV过滤剂; （b2）丁基甲氧基二苯甲酰基甲烷; （b3）二乙基己基丁酰氨基三嗪酮; （b4）乙基己基三嗪酮; （b5）二乙氨基羟苯甲酰基苯甲酸己酯; （b6）甲氧基肉桂酸乙基己酯; （b7）水杨酸乙基己酯; （b8）胡莫柳油; （b9）奥克立林; （b10）微粉化的亚甲基双 - 苯并三唑基四甲基丁基苯酚; （b11）苯基苯并咪唑磺酸; （b12）二氧化钛; （b13）微粉化的三联苯三嗪; 和（b14）微粉化（2- {4- [2-（4-二乙基氨基-2-羟基 - 苯甲酰基） - 苯甲酰基] - 哌嗪-1-羰基} - 苯基） - （4-二乙基氨基-2-羟基 - 苯基） - 甲酮; （b15）苯甲酸，4,4 - [[3- [1,3,3,3-四甲基-1- [三甲基甲硅烷基]氧基] -1-二硅氧烷基]丙基]氨基] -1,3,5-三嗪-2 （b1） - （b14）的至少2个紫外线过滤剂;其中所述紫外线过滤剂组合物包含至少2种组分（b1） - （b14）的紫外线过滤剂; 用于保护人类和动物毛发和皮肤免受紫外线辐射。

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