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    • 2. 发明申请
    • SYSTEMS, APPARATUS, AND METHODS FOR GENERATING AND ANALYZING RESISTOME PROFILES
    • 用于生成和分析RESISTOME PROFILES的系统,设备和方法
    • WO2015184017A1
    • 2015-12-03
    • PCT/US2015/032761
    • 2015-05-27
    • OPGEN, INC.
    • JONES, EvanSAPIRO, VadimWALKER, George TerranceSAEED, Alex
    • G06F19/18
    • G06F19/24G06F19/18G06F19/26
    • Systems, apparatus, and methods are disclosed for generating a resistome profile for a subject, monitoring an infection state of one or more subjects, and/or identifying a potential infection outbreak at a facility, for example, by obtaining first data representative of at least one measure of antibiotic resistance of an organism from a first sample, identifying the organism, determining at least one of an antibiotic susceptibility phenotype, an identity of an antibiotic resistance gene, and an antibiotic to which the organism is non-susceptible, generating and comparing a first pattern to at least one known pattern to determine and generate a profile uniqueness identifier indicating a degree of similarity above a threshold between the first pattern and the at least one known pattern.
    • 公开了系统,装置和方法,用于为受试者产生阻塞症状,监测一个或多个受试者的感染状态和/或识别设施处的潜在的感染爆发,例如通过获得至少代表至少 测定来自第一样品的生物体的抗生素抗性,鉴定生物体,确定抗生素敏感性表型,抗生素抗性基因的身份和生物体不易感染的抗生素中的至少一种,产生和比较 至少一个已知模式的第一模式,以确定和生成指示在所述第一模式和所述至少一种已知模式之间的阈值之上的相似度的简档唯一性标识符。