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1. 发明申请

WO2011005867A8 POLYPEPTIDES HAVING CELLULOLYTIC ENHANCING ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
公开(公告)号：WO2011005867A8
公开(公告)日：2011-08-11
申请号：PCT/US2010041222
申请日：2010-07-07
申请人： NOVOZYMES INC , NOVOZYMES AS , DUAN JUNXIN , TANG LAN , LIU YE , WU WENPING , QUINLAN JASON , KRAMER RANDALL
发明人： DUAN JUNXIN , TANG LAN , LIU YE , WU WENPING , QUINLAN JASON , KRAMER RANDALL
IPC分类号： C12N15/82 , C12N9/24
CPC分类号： C12N15/8246 , C07K14/4705 , C12N9/2437 , C12N9/86 , C12Y302/01004 , C12Y305/02006
摘要： The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
摘要翻译：本发明涉及具有纤维素分解增强活性的分离的多肽和编码所述多肽的分离的多核苷酸。本发明还涉及包含所述多核苷酸的核酸构建体，载体和宿主细胞以及生产和使用所述多肽的方法。

2. 发明申请

WO2004055178A9 THERMOSTABLE ALPHA-AMYLASES 审中-公开
标题翻译：可热稳定的α-淀粉酶
公开(公告)号：WO2004055178A9
公开(公告)日：2004-10-07
申请号：PCT/DK0300882
申请日：2003-12-16
申请人： NOVOZYMES AS , TANG LAN , WU WENPING , DUAN JUNXIN , JOHANNESEN PIA FRANCKE
发明人： TANG LAN , WU WENPING , DUAN JUNXIN , JOHANNESEN PIA FRANCKE
IPC分类号： C12N9/26 , C12N9/30 , C12N15/56
CPC分类号： C12N9/242 , A21D8/042 , C12C11/003 , C12N9/2414 , C12P7/02 , C12P19/12 , C12P19/14 , C12Y302/01001 , D06M16/003 , Y02E50/17
摘要： An isolated polynucleotide comprising an open reading frame encoding a polypeptide having alpha-amylase activity, the polypeptide selected from the group consisting of: a) a polypeptide comprising an amino acid sequencewhich has at least 70% identity with amino acids 22 to 450 of SEQ ID NO:4; b) a polypeptide comprising an amino acid sequence which has at least 70% identity with the polypeptide encoded by the amylase encoding part of the polynucleotide inserted into a plasmid present in the E. coli host deposited under the Budapest Treaty with DSMZ under accession number DSM 15334; c) a polypeptide encoded by a polynucleotide comprising a nucleotide sequence which has at least 70% identity with the sequence shown from position 68 to 1417 in SEQ ID NO:3; and d) a fragment of (a), (b) or (c) that has alpha-amylase activity.
摘要翻译：一种分离的多核苷酸，其包含编码具有α-淀粉酶活性的多肽的开放阅读框，所述多肽选自：a）包含与SEQ ID NO：22的氨基酸22至450具有至少70％同一性的氨基酸序列的多肽 NO：4; b）一种多肽，其包含氨基酸序列，该氨基酸序列与插入存在于根据布达佩斯条约与DSMZ保藏的大肠杆菌宿主的质粒存在的质粒的多核苷酸编码的多肽编码的多肽相同， 15334; c）由多核苷酸编码的多肽，其包含与SEQ ID NO：3中的位置68至1417所示的序列具有至少70％同一性的核苷酸序列; 和d）具有α-淀粉酶活性的（a），（b）或（c）的片段。

3. 发明申请

WO2006069290A3 ENZYMES FOR STARCH PROCESSING 审中-公开
标题翻译：淀粉加工酶
公开(公告)号：WO2006069290A3
公开(公告)日：2007-05-31
申请号：PCT/US2005046725
申请日：2005-12-22
申请人： NOVOZYMES AS , NOVOZYMES NORTH AMERICA INC , FUKUYAMA SHIRO , MATSUI TOMOKO , SOONG CHEE-LEONG , ALLAIN ERIC , VIKSO-NIELSEN ANDERS , UDAGAWA HIROAKI , LIU YE , DUAN JUNXIN , WU WENPING , ANDERSEN LENE NONBOE , LANDVIK SARA
发明人： FUKUYAMA SHIRO , MATSUI TOMOKO , SOONG CHEE-LEONG , ALLAIN ERIC , VIKSO-NIELSEN ANDERS , UDAGAWA HIROAKI , LIU YE , DUAN JUNXIN , WU WENPING , ANDERSEN LENE NONBOE , LANDVIK SARA
IPC分类号： C12N9/32 , C07H21/04 , C12N1/16 , C12N15/74
CPC分类号： C12P19/14 , C07K2319/00 , C12N9/242 , C12N9/2428 , C12P7/06 , C12P19/02 , C12Y302/01001 , C12Y302/01003 , Y02E50/17
摘要： The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and an alpha-amylase amino acid sequence as well as to the application of such polypeptides.
摘要翻译：本发明涉及包含碳水化合物结合组件氨基酸序列和α-淀粉酶氨基酸序列以及这些多肽的应用的多肽。

4. 发明申请

WO2004056981A3 POLYPEPTIDES HAVING CELLOBIOHYDROLASE II ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：具有环糊精II活性的多肽和编码其的多核苷酸
公开(公告)号：WO2004056981A3
公开(公告)日：2004-11-11
申请号：PCT/DK0300914
申请日：2003-12-19
申请人： NOVOZYMES AS , WU WENPING , LANGE LENE , SKOVLUND DOMINIQUE AUBERT , LIU YE
发明人： WU WENPING , LANGE LENE , SKOVLUND DOMINIQUE AUBERT , LIU YE
IPC分类号： C11D3/386 , C12N9/42
CPC分类号： C11D3/38645 , C12N9/2437 , C12P7/06 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： The present invention relates to polypeptides having cellobiohydrolase II activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides, e.g. for producing ethanol from biomass or for shuffling of DNA.
摘要翻译：本发明涉及具有纤维二糖水解酶II活性的多肽和具有编码多肽的核苷酸序列的多核苷酸。本发明还涉及包含核酸构建体的核酸构建体，载体和宿主细胞，以及用于产生和使用多肽的方法。用于从生物量生产乙醇或进行洗牌。

5. 发明申请

WO2004072279A2 PROTEASES 审中-公开
标题翻译：蛋白酶
公开(公告)号：WO2004072279A2
公开(公告)日：2004-08-26
申请号：PCT/DK2004000091
申请日：2004-02-09
申请人： NOVOZYMES AS , PONTOPPIDAN KATRINE , WU WENPING , LAN TANG , LIU YE , MARIA LEONARDO DE
发明人： PONTOPPIDAN KATRINE , WU WENPING , LAN TANG , LIU YE , DE MARIA LEONARDO
IPC分类号： C12N9/52 , C12N9/58 , C12N15/57 , A23J3/34 , C12N9/64
CPC分类号： C12N9/52 , A01K2217/05 , C12N9/58 , C12N2310/111
摘要： The invention relates to a sub-class of novel proteases with distinct differences of expected structural relevance to known proteases of Metarhizium and Nocardiopsis. The sub-class encompasses proteases derived from Gliocladium, Periconia, Curvularia, and Brachysporiella. The invention also relates to DNA encoding such proteases, the expression thereof in a host cell, including animal and plant cells, as well as to the use thereof, e.g. in animal feed and in detergents. The invention furthermore relates to the use in animal feed of proteases of at least 55% identity to the protease derived from Brachysporiella. The Metarhizium protease is an The invention relates to a sub-class of novel proteases with distinct differences of expected structural relevance to known proteases of Metarhizium and Nocardiopsis. The sub-class encompasses proteases derived from Gliocladium, Periconia, Curvularia, and Brachysporiella. The invention also relates to DNA encoding such proteases, the expression thereof in a host cell, including animal and plant cells, as well as to the use thereof, e.g. in animal feed and in detergents. The invention furthermore relates to the use in animal feed of proteases of at least 55% identity to the protease derived from Brachysporiella. The Metarhizium protease is an example of such proteases.
摘要翻译：本发明涉及具有与已知的绿僵菌和拟诺卡氏菌蛋白酶的预期结构相关性明显不同的新型蛋白酶的亚类。亚类包括来源于粘帚霉（Gliocladium），Periconia，弯孢属（Curvularia）和短柄螺属（Brachysporiella）的蛋白酶。本发明还涉及编码这种蛋白酶的DNA，其在包括动物和植物细胞的宿主细胞中的表达，以及其用途，例如，在动物饲料和洗涤剂中。本发明还涉及在动物饲料中与来源于短柄螺属的蛋白酶具有至少55％同一性的蛋白酶的用途。 Metarhizium蛋白酶是一种新型蛋白酶的亚类，与已知的绿僵菌和拟诺卡氏菌蛋白酶的预期结构相关性有明显差异。亚类包括来源于粘帚霉（Gliocladium），Periconia，弯孢属（Curvularia）和短柄螺属（Brachysporiella）的蛋白酶。本发明还涉及编码这种蛋白酶的DNA，其在包括动物和植物细胞的宿主细胞中的表达，以及其用途，例如，在动物饲料和洗涤剂中。本发明还涉及在动物饲料中与来源于短柄螺属的蛋白酶具有至少55％同一性的蛋白酶的用途。 Metarhizium蛋白酶是这类蛋白酶的一个例子。

6. 发明申请

WO2005080559B1 FUNGALL CELL WALL DEGRADING ENZYME 审中-公开
公开(公告)号：WO2005080559B1
公开(公告)日：2005-09-29
申请号：PCT/DK2005000099
申请日：2005-02-16
申请人： NOVOZYMES AS , WU WENPING , SCHNORR KIRK MATTHEW
发明人： WU WENPING , SCHNORR KIRK MATTHEW
IPC分类号： A23K1/16 , A23K1/165 , A61K8/64 , A61K8/66 , A61K38/00 , A61K38/47 , A61Q11/00 , C11D3/386 , C12N9/36 , A61K7/28 , C12N15/56
CPC分类号： C12N9/2462 , A23K20/147 , A23K20/189 , A61K8/64 , A61K38/00 , A61Q11/00 , C11D3/386 , C11D3/38636
摘要： A novel fungal enzyme having lysozyme activity has been isolated. The invention further relates to a fungal polypeptide having lysozyme activity and belonging to the GH25 family, wherein the enzyme is selected from the group consisting of (a) a polypeptide comprising an amino acid sequence, which has at least 80% identity with amino acids 1 to 233 of SEQ ID NO:2; (b) a polypeptide comprising an amino acid sequence, which has at least 80% identity with the polypeptide encoded by the lysozyme encoding part of the nucleotide sequence inserted into a plasmid present in strain DSM16084; (c) a polypeptide which is encoded by a nucleotide sequence which hybridizes under high stringency conditions with a polynucleotide probe consisting of the complementary strand of nucleotides 84 to 782 of SEQ ID NO:1; or (d) a fragment of (a), (b) or (c) that has lysozyme activity.
摘要翻译：已经分离出具有溶菌酶活性的新型真菌酶。本发明还涉及具有溶菌酶活性并属于GH25家族的真菌多肽，其中所述酶选自（a）包含氨基酸序列的多肽，所述氨基酸序列与氨基酸1具有至少80％的同一性至233的SEQ ID NO：2; （b）包含氨基酸序列的多肽，所述氨基酸序列与插入到菌株DSM16084中存在的质粒中的编码核苷酸序列的部分的溶菌酶编码的多肽具有至少80％的同一性; （c）由在高严格条件下与SEQ ID NO：1的核苷酸84至782的互补链组成的多核苷酸探针的核苷酸序列编码的多肽; 或（d）具有溶菌酶活性的（a），（b）或（c）的片段。

7. 发明申请

WO03000941A2 POLYPEPTIDES HAVING CELLOBIOHYDROLASE I ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
标题翻译：具有环糊精I活性的多肽和编码其的多核苷酸
公开(公告)号：WO03000941A2
公开(公告)日：2003-01-03
申请号：PCT/DK0200429
申请日：2002-06-26
申请人： NOVOZYMES AS , LANGE LENE , WU WENPING , AUBERT DOMINIQUE , LANDVIK SARA , SCHNORR KIRK MATTHEW , CLAUSEN IB GROTH
发明人： LANGE LENE , WU WENPING , AUBERT DOMINIQUE , LANDVIK SARA , SCHNORR KIRK MATTHEW , CLAUSEN IB GROTH
IPC分类号： C07H21/04 , C07K16/40 , C12N9/00 , C12N9/42 , C12N15/55 , C12S11/00 , C21C1/00 , C21N
CPC分类号： C12N9/2437 , C11D3/386 , C11D3/38645 , C12N9/2408 , C12N9/2477 , C12P7/14 , C12Y302/01091 , Y02E50/16 , Y02E50/17
摘要： Abstract The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
摘要翻译：摘要本发明涉及具有纤维二糖水解酶I活性的多肽和具有编码多肽的核苷酸序列的多核苷酸。本发明还涉及包含核酸构建体的核酸构建体，载体和宿主细胞以及用于产生和使用多肽的方法。

8. 发明申请

WO2004050696A2 ANTIMICROBIAL POLYPEPTIDE ISOLATED FROM RHIZOMUCOR PUSILLUS 审中-公开
标题翻译：从促红细菌分离的抗微生物多肽
公开(公告)号：WO2004050696A2
公开(公告)日：2004-06-17
申请号：PCT/DK0300831
申请日：2003-12-04
申请人： NOVOZYMES AS , SCHNORR KIRK MATTHEW , WU WENPING
发明人： SCHNORR KIRK MATTHEW , WU WENPING
IPC分类号： A01N37/46 , A01N63/04 , C07K14/37 , C07K14/46
CPC分类号： C07K14/37 , A01N37/46 , A01N63/04
摘要： The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
摘要翻译：本发明涉及具有抗微生物活性的多肽和具有编码该多肽的核苷酸序列的多核苷酸。本发明还涉及包含核酸构建体的核酸构建体，载体和宿主细胞以及生产和使用该多肽的方法。

9. 发明申请

WO0196536A2 ASPARTIC ACID PROTEASES AND NUCLEIC ACIDS ENCODING SAME 审中-公开
标题翻译：味精酸蛋白和核酸编码相同
公开(公告)号：WO0196536A2
公开(公告)日：2001-12-20
申请号：PCT/DK0100379
申请日：2001-05-31
申请人： NOVOZYMES AS
发明人： WU WENPING , OESTERGAARD PETER R , KAUPPINEN MARKUS S
IPC分类号： C12N9/64 , C12P7/06 , C12N9/00
CPC分类号： C12N9/6413 , C12P7/06 , Y02E50/17
摘要： The present invention relates to novel isolated aspartic acid proteases and isolated nucleic acid sequences encoding such aspartic acid proteases. The present invention also relates to nucleic acid constructs, vectors and host cells comprising the nucleic acid sequences as well as to methods for producing and using the aspartic acid proteases.
摘要翻译：本发明涉及新型分离的天冬氨酸蛋白酶和分离的编码这种天冬氨酸蛋白酶的核酸序列。本发明还涉及包含核酸序列的核酸构建体，载体和宿主细胞以及用于产生和使用天冬氨酸蛋白酶的方法。

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