专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO1997000948A1 OXIDASE, MICROORGANISMS PRODUCING THE SAME AND USE OF THE SAME 审中-公开
标题翻译：氧化物，生产相同的微生物和使用它们
公开(公告)号：WO1997000948A1
公开(公告)日：1997-01-09
申请号：PCT/JP1996001594
申请日：1996-06-12
申请人： NOVO NORDISK A/S , ECHIGO, Takashi , OHNO, Ritsuko , FUKUYAMA, Shiro
发明人： NOVO NORDISK A/S
IPC分类号： C12N09/02
CPC分类号： C12Y110/03001 , C11D3/38654 , C12N9/0004 , C12N9/0059 , C12P7/22 , C12R1/645 , D06L4/12 , D21C5/005
摘要： A polyphenol oxidase which is produced by bacteria belonging to the genus Myrothecium and has the optimum pH value in the alkaline region of pH (8) or above; a process for producing the oxidase; Myrothecium verrucaria SD3001 (FERM P-14955) and Myrothecium roridum SD3002 (FERM P-15225) which are novel microorganisms producing the oxidase; and use of the oxidase in the fields of oxidizing, washing, etc. of colored materials and polyphenol-containing materials.
摘要翻译：一种多酚氧化酶，其由属于黑腹菌属的细菌产生，并且在pH（8）以上的碱性区域具有最佳pH值; 一种生产氧化酶的方法; 作为产生氧化酶的新型微生物的疣状疟原虫SD3001（FERM P-14955）和罗非鱼SD3002（FERM P-15225）以及在着色材料和含多酚材料的氧化，洗涤等领域中使用氧化酶。

2. 发明申请

WO1997028257A1 BACTERIAL POLYPHENOL OXIDASE FROM BACILLUS FOR USE IN OXIDATION OF COLORED SUBSTANCES 审中-公开
标题翻译：来自BACILLUS的细菌多酚氧化酶用于着色物质的氧化
公开(公告)号：WO1997028257A1
公开(公告)日：1997-08-07
申请号：PCT/DK1997000038
申请日：1997-01-29
申请人： NOVO NORDISK A/S , ECHIGO, Takashi , OHNO, Ritsuko
发明人： NOVO NORDISK A/S
IPC分类号： C12N09/02
CPC分类号： C12N9/0059 , C11D3/0021 , C11D3/38654 , D06L4/10 , D21C5/005
摘要： A novel polyphenol oxidase is produced extracellularly by bacteria, particularly from the genus Bacillus. The enzyme is useful for bleaching and oxidizing a variety of substrates.
摘要翻译：一种新的多酚氧化酶由细菌，特别是芽孢杆菌属细菌细胞外产生。该酶可用于漂白和氧化各种底物。

3. 发明申请

WO1997016541A1 ALKALINE PROTEASE, PROCESS FOR THE PRODUCTION THEREOF, USE THEREOF, AND MICROORGANISM PRODUCING THE SAME 审中-公开
标题翻译：碱性蛋白酶，其生产方法，用途及其生产的微生物
公开(公告)号：WO1997016541A1
公开(公告)日：1997-05-09
申请号：PCT/JP1996003216
申请日：1996-11-01
申请人： NOVO NORDISK A/S , MIYOTA, Yoshiaki , FUKUYAMA, Shiro , YONEDA, Tadashi
发明人： NOVO NORDISK A/S
IPC分类号： C12N09/54
CPC分类号： C12R1/07 , C11D3/386 , C11D3/38609 , C11D3/38618 , C12N9/54
摘要： A novel strain of Bacillus sp. (accession number: FERM BP-5736) and a protease which is obtained by incubating this strain or its variant, shows a high stability in the presence of surfactants, and has the following properties: (1) hydrolyzing proteins and peptides; (2) having an optimum pH value of around 12, when reacted with the use of casein as the substrate at 30 DEG C for 10 minutes; (3) having a stable pH value of from 5 to 11, when incubated with the use of casein as the substrate at 30 DEG C for 24 hours; (4) having an optimum action temperature of around 60 DEG C, when reacted with the use of casein as the substrate at pH 10 for 10 minutes; (5) having a molecular weight of 29,000 +/- 2,000 determined by SDS polyacrylamide gel electrophoresis; (6) having an isoelectric piont of 10.1 +/- 0.5 determined by isoelectric polyacrylamide gel electrphoresis; and (7) having a residual activity of 60 % or above in a 500 ppm LAS solution after 30 minutes at 40 DEG C or 20 % or above after 15 minutes at 55 DEG C.
摘要翻译：一种新型芽孢杆菌菌株（登录号：FERM BP-5736）和通过温育该菌株或其变体获得的蛋白酶在表面活性剂存在下显示出高稳定性，具有以下性质：（1）水解蛋白质和肽; （2）当在30℃下与酪蛋白作为底物反应10分钟时，具有约12的最佳pH值; （3）当在30℃下使用酪蛋白作为底物孵育24小时时，其稳定的pH值为5至11; （4）在pH 10下与酪蛋白作为底物反应10分钟时，具有约60℃的最佳作用温度; （5）通过SDS聚丙烯酰胺凝胶电泳测定分子量为29,000 +/- 2,000; （6）通过等电聚丙烯酰胺凝胶电泳测定等电点为10.1 +/- 0.5; 和（7）在55℃下在30分钟后在30分钟内在500ppm LAS溶液中具有60％或更高的残留活性，在55℃下15分钟后具有20％或更高的残余活性。

4. 发明申请

WO1998005765A1 DOUBLE-STRANDED DNA WITH COHESIVE END(S), AND METHOD OF SHUFFLING DNA USING THE SAME 审中-公开
标题翻译：具有粘结末端的双链DNA和使用其的DNA的方法
公开(公告)号：WO1998005765A1
公开(公告)日：1998-02-12
申请号：PCT/DK1997000317
申请日：1997-07-23
申请人： NOVO NORDISK A/S , MIYOTA, Yoshiaki , FUKUYAMA, Shiro
发明人： NOVO NORDISK A/S
IPC分类号： C12N15/10
CPC分类号： C12N15/10 , C12N15/1027 , C12N15/66 , C12Q1/68 , C12Q1/6811
摘要： To provide a method of mutation of DNAs, which is substantially different from the conventional methods applicable to naturally-existing DNAs, and also to provide useful genetic products to be produced by the use of thus-mutated DNAs. A DNA with a cohesive end comprising (a) a double-stranded DNA having the same sequence as that of a part of a gene, and (b) a single-stranded DNA having a base sequence that exists on said gene at the site not adjoining the part corresponding to said double-stranded DNA or a base sequence which said gene does not have, wherein the single-stranded DNA is linked to either one end of the double-stranded DNA to form a cohesive end; a method for producing it; a method of shuffling a DNA using it; a DNA and a DNA pool to be obtained by the shuffling method; a method for producing the DNA pool; and a genetic product to be obtained by expressing the genetic information existing in the DNA pool.
摘要翻译：提供DNA的突变方法，其与适用于天然存在的DNA的常规方法基本上不同，并且还提供通过使用由此突变的DNA产生的有用的遗传产物。具有粘性末端的DNA包含（a）与基因的一部分具有相同序列的双链DNA，和（b）在所述位点处存在于所述基因上的碱基序列的单链DNA，邻接对应于所述双链DNA的部分或所述基因不具有的碱基序列，其中所述单链DNA连接到所述双链DNA的任一端以形成粘性末端; 一种生产它的方法; 使用它洗脱DNA的方法; 通过洗牌法获得的DNA和DNA库; 一种生产DNA池的方法; 以及通过表达DNA池中存在的遗传信息而获得的遗传产物。

5. 发明申请

WO1998005764A1 NUCLEIC ACID POOL AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：核酸池及其生产方法
公开(公告)号：WO1998005764A1
公开(公告)日：1998-02-12
申请号：PCT/DK1997000316
申请日：1997-07-23
申请人： NOVO NORDISK A/S , MIYOTA, Yoshiaki , FUKUYAMA, Shiro
发明人： NOVO NORDISK A/S
IPC分类号： C12N15/10
CPC分类号： C12N9/54 , C12N15/10
摘要： To efficiently provide a number of base sequences existing in spaces significantly apart from naturally-existing base sequence spaces. A nucleic acid pool comprising two or more different nucleic acids, which is constructed by dividing all or a part of one or more genes into 3 or more blocks followed by ligating all or a part of these blocks into sequences that are different from the sequence or sequences of the original, non-divided gene or genes, and a method for producing the pool; and also a genetic product to be obtained by expressing the genetic information existing in the nucleic acid pool.
摘要翻译：为了有效地提供存在于空间中的许多碱基序列，其显着远离天然存在的碱基序列空间。包含两个或更多个不同核酸的核酸池，其通过将一个或多个基因的全部或部分划分为3个或更多个嵌段，然后将这些嵌段的全部或部分连接到不同于该序列的序列或原始的，未分裂的基因或基因的序列，和用于产生游泳池的方法; 以及通过表达存在于核酸池中的遗传信息而获得的遗传产物。

6. 发明申请

WO1998028409A1 PHYTASE POLYPEPTIDES 审中-公开
公开(公告)号：WO1998028409A1
公开(公告)日：1998-07-02
申请号：PCT/DK1997000568
申请日：1997-12-15
申请人： NOVO NORDISK A/S
发明人： NOVO NORDISK A/S , LASSEN, Soren, Flensted , BECH, Lisbeth , OHMANN, Anders , BREINHOLT, Jens , FUGLSANG, Claus, Crone
IPC分类号： C12N09/16
CPC分类号： C12Y301/03026 , A23K20/189 , A23L5/25 , A23L29/06 , C12N9/16
摘要： The present invention relates to isolated polypeptides having phytase activity, the corresponding cloned DNA sequences, a process for preparing such polypeptides, and the use thereof for a number of industrial applications. In particular, the invention relates to phytases derived from the phyllum Basidiomycota, phytases of certain consensus sequences and fungal 6-phytases.
摘要翻译：本发明涉及具有植酸酶活性的分离的多肽，相应的克隆的DNA序列，制备该多肽的方法及其在许多工业应用中的应用。特别地，本发明涉及源自担子菌的植酸酶，某些共有序列的植酸酶和真菌6-肌醇六磷酸酶。

7. 发明申请

WO1998020895A1 USE OF GLP-1 PEPTIDES 审中-公开
标题翻译：使用GLP-1肽
公开(公告)号：WO1998020895A1
公开(公告)日：1998-05-22
申请号：PCT/DK1997000509
申请日：1997-11-07
申请人： NOVO NORDISK A/S , KNUDSEN, Liselotte, Bjerre , THIM, Lars , JUDGE, Martin, Edward , HOLST, Jens, Juul , ASTRUP, Arne, Vernon , WULFF, Brigitte, Schjellerup
发明人： NOVO NORDISK A/S
IPC分类号： A61K38/26
CPC分类号： A61K38/26
摘要： GLP-1(1-45) or a fragment or an analogue thereof can be used in the preparation of a medicament for peripheral administration in the suppression of appetite or induction of satiety.
摘要翻译： GLP-1（1-45）或其片段或类似物可用于制备用于抑制食欲或诱导饱腹感的外周施用的药物。

8. 发明申请

WO1998020136A1 GLUCOSE OXIDASES 审中-公开
标题翻译：葡萄糖氧化
公开(公告)号：WO1998020136A1
公开(公告)日：1998-05-14
申请号：PCT/US1997020174
申请日：1997-11-03
申请人： NOVO NORDISK BIOTECH, INC. , NOVO NORDISK A/S
发明人： NOVO NORDISK BIOTECH, INC. , NOVO NORDISK A/S , CHERRY, Joel, R. , BERKA, Randy, M. , HALKIER, Torben
IPC分类号： C12N15/53
CPC分类号： C12N9/0006
摘要： The invention is directed to alkaline glucose oxidases comprising novel peptide sequences. Furthermore, the invention relates to methods for producing and using said glucose oxidases.
摘要翻译：本发明涉及包含新肽序列的碱性葡萄糖氧化酶。此外，本发明涉及生产和使用所述葡萄糖氧化酶的方法。

9. 发明申请

WO1998018776A1 NOVEL CIS-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES 审中-公开
公开(公告)号：WO1998018776A1
公开(公告)日：1998-05-07
申请号：PCT/DK1997000483
申请日：1997-10-28
申请人： NOVO NORDISK A/S
发明人： NOVO NORDISK A/S , JACOBSEN, Poul , TREPPENDAHL, Svend , STANLEY BURY, Paul , KANSTRUP, Anders , BROWN CHRISTIANSEN, Lise
IPC分类号： C07D311/74
CPC分类号： C07D413/04 , C07D311/58
摘要： The present invention relates to therapeutically active compounds of formula (I), a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.

10. 发明申请

WO1998018771A1 NOVEL (-)-ENANTIOMERS OF CIS-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES 审中-公开
标题翻译：新的（ - ） - CIS-3,4-CHROMAN衍生物的有效用于预防或治疗雌激素相关疾病或综合症
公开(公告)号：WO1998018771A1
公开(公告)日：1998-05-07
申请号：PCT/DK1997000478
申请日：1997-10-28
申请人： NOVO NORDISK A/S
发明人： NOVO NORDISK A/S , JACOBSEN, Paul , TREPPENDAHL, Svend , BURY, Paul, Stanley , KANSTRUP, Anders , CHRISTIANSEN, Lise, Brown
IPC分类号： C07D311/74
CPC分类号： C07D311/74
摘要： The present invention relates to therapeutically active compounds of formula (I), a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in the prevention or treatment of estrogen related diseases or syndromes.
摘要翻译：本发明涉及式（I）的治疗活性化合物，其制备方法和包含该化合物的药物组合物。新型化合物可用于预防或治疗雌激素相关疾病或综合征。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式