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1. 发明申请

WO2009126685A3 SYSTEMS AND METHODS FOR COUNTING CELLS AND BIOMOLECULES 审中-公开
公开(公告)号：WO2009126685A3
公开(公告)日：2009-10-15
申请号：PCT/US2009/039863
申请日：2009-04-08
申请人： NEXCELOM BIOSCIENCE , LIN, Bo , LI, Peter , QIU, Jean , SMITH, Timothy , SOBOLEWSKI, Todd , PIRANI, Alnoor
发明人： LIN, Bo , LI, Peter , QIU, Jean , SMITH, Timothy , SOBOLEWSKI, Todd , PIRANI, Alnoor
IPC分类号： C12M1/34 , C12Q1/00 , G02B21/34
摘要： The present invention generally relates to systems and methods for counting biomolecules or cells. In certain embodiments, the invention provides a cell counting or biomolecule counting system including: a covered chamber having a known height and configured to hold a suspension of biomolecules or cells in a sample; at least one fluorescent light source connected to at least one fluorescent light beam narrowing device; a bright-field light source connected to a bright-field light beam narrowing device; a microscope objective; a detection device; a fluorescent filter assembly to allow only excitation light to illuminate the sample and allow only emission light from the sample to be imaged by the detection device; and a movable light shutter to block bright-field light during fluorescent detection.

2. 发明申请

WO2003064995A3 A GUIDED MODE RESONANT FILTER BIOSENSOR USING A LINEAR GRATING SURFACE STRUCTURE 审中-公开
公开(公告)号：WO2003064995A3
公开(公告)日：2003-08-07
申请号：PCT/US2003/001175
申请日：2003-01-16
申请人： SRU BIOSYSTEMS, LLC , CUNNINGHAM, Brian, T. , PEPPER, Jane , LIN, Bo , LI, Peter , QIU, Jean , PIEN, Homer
发明人： CUNNINGHAM, Brian, T. , PEPPER, Jane , LIN, Bo , LI, Peter , QIU, Jean , PIEN, Homer
IPC分类号： G01N33/543
摘要： Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters.

3. 发明申请

WO2006085958A2 INTEGRATION OF DIRECT BINDING SENSORS WITH MASS SPECTROMETRY FOR FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF MOLECULES 审中-公开
标题翻译：直接结合传感器与质谱联用分子功能和结构表征
公开(公告)号：WO2006085958A2
公开(公告)日：2006-08-17
申请号：PCT/US2005/022719
申请日：2005-06-28
申请人： SRU BIOSYSTEMS, INC. , LI, Peter , LIN, Bo , WILLIAMS, Chris , LAING, Lance
发明人： LI, Peter , LIN, Bo , WILLIAMS, Chris , LAING, Lance
IPC分类号： G01N21/27 , G01N33/487 , G01N33/543
CPC分类号： G01N33/6848 , G01N21/27 , G01N33/542 , G01N33/543 , G01N33/54373
摘要： The invention provides methods for the detection, quantification, identification and structural analysis of one or more molecules. Mass spectrometry (MS) is not a universal detector as all molecules do not ionize equally well leading to poor signal to quantity information. MS can be optimized to identify the specific mass of a binding component when the presence of a material is known. Colorimetric resonant reflectance optical sensors provide a universal mass detector in that nearly all biological masses give equally proportional signals. The combined methods allow selection and or detection with quantification of all masses binding to the sensor with the ability to identify specific molecules by their individual masses and structure analyses.
摘要翻译：本发明提供了用于一种或多种分子的检测，定量，鉴定和结构分析的方法。质谱（MS）不是一种通用的检测器，因为所有分子都不能很好地电离，导致信号量差的信息。当材料的存在已知时，MS可以被优化以识别结合成分的特定质量。比色共振反射光学传感器提供了一个通用质量检测器，几乎所有的生物质量都可以提供同等比例的信号。这些组合方法允许选择和检测所有与传感器结合的质量，并能够通过各自的质量和结构分析来识别特定分子。

4. 发明申请

WO2005031349A2 LABEL-FREE METHODS FOR PERFORMING ASSAYS USING A COLORIMETRIC RESONANT REFLECTANCE OPTICAL BIOSENSOR 审中-公开
标题翻译：使用彩色共振反射光学生物传感器进行测试的无标签方法
公开(公告)号：WO2005031349A2
公开(公告)日：2005-04-07
申请号：PCT/US2004/030893
申请日：2004-09-22
申请人： SRU BIOSYSTEMS, INC. , LIN, Bo , CUNNINGHAM, Brian, T. , LI, Peter
发明人： LIN, Bo , CUNNINGHAM, Brian, T. , LI, Peter
IPC分类号： G01N33/50
CPC分类号： B01L3/5085 , C12Q1/6816 , C40B30/04 , C40B30/10 , G01N21/253 , G01N21/255 , G01N21/4788 , G01N21/7743 , G01N33/54366 , G01N33/54373 , G02B5/1809 , Y10S435/808 , Y10S436/805 , Y10S436/809
摘要： The instant invention provides compositions and methods for determining cell interactions that are faster than conventional methods and that require the use of fewer reagents than conventional methods.
摘要翻译：本发明提供了用于确定细胞相互作用的组合物和方法，其比常规方法更快，并且需要使用比常规方法更少的试剂。

5. 发明申请

WO2012150910A1 FIBER BRAGG GRATING (FBG) SENSOR 审中-公开
标题翻译：光纤光栅（FBG）传感器
公开(公告)号：WO2012150910A1
公开(公告)日：2012-11-08
申请号：PCT/SG2012/000157
申请日：2012-05-04
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , HAO, Jianzhong , DONG, Bo , PAULOSE, Varghese , LIN, Bo
发明人： HAO, Jianzhong , DONG, Bo , PAULOSE, Varghese , LIN, Bo
IPC分类号： G01L1/24 , G02B6/02 , G08B13/12
CPC分类号： G01L1/246 , G02B6/02209 , G02B6/2558 , G02B6/34 , G08B13/124 , Y10T29/49826
摘要： A fiber Bragg grating (FBG) sensor structure, a method of fabricating a FBG sensor structure, and a method of employing a FBG sensor structure comprising an optical fiber portion having at least one FBG formed therein. The FBG sensor structure comprises an optical fiber portion having at least one FBG formed therein; and a sleeve structure capable of transferring vibrations and/or strain along a length thereof; wherein the optical fiber portion is coupled to the sleeve structure such that the central wavelength of the FBG, is variable under the transferred vibrations and/or strain.
摘要翻译：光纤布拉格光栅（FBG）传感器结构，FBG传感器结构的制造方法以及采用FBG传感器结构的方法，所述FBG传感器结构包括其中形成有至少一个FBG的光纤部分。 FBG传感器结构包括其中形成有至少一个FBG的光纤部分; 以及能够沿其长度传递振动和/或应变的套筒结构; 其中光纤部分耦合到套筒结构，使得FBG的中心波长在转移的振动和/或应变下是可变的。

6. 发明申请

WO2008040393A1 ERROR CORRECTION APPARATUS, METHOD OF CORRECTING AN ERROR AND METHOD OF GENERATING ERROR LOCATION DATA 审中-公开
标题翻译：错误校正装置，校正错误的方法和产生错误位置数据的方法
公开(公告)号：WO2008040393A1
公开(公告)日：2008-04-10
申请号：PCT/EP2006/067114
申请日：2006-10-05
申请人： FREESCALE SEMICONDUCTOR, INC. , LIN, Bo , EDMISTON, Graham
发明人： LIN, Bo , EDMISTON, Graham
IPC分类号： H03M13/09 , H04L1/00
CPC分类号： H03M13/09 , H04L1/0061 , H04L1/0072
摘要： An error correction apparatus (100) comprises an input (102) for receiving data (300). The received data includes error-check data (304). The apparatus (100) also includes a processing resource (106) arranged to calculate parity check data. A data store (110) is coupled to the processing resource (106) for storing look-up data for identifying, when in use, a location of an error in the received data (300). The look-up data is a compressed form of indexed error location data (200).
摘要翻译：纠错装置（100）包括用于接收数据（300）的输入（102）。所接收的数据包括错误检查数据（304）。设备（100）还包括被配置为计算奇偶校验数据的处理资源（106）。数据存储器（110）耦合到处理资源（106），用于存储用于在使用中识别接收数据（300）中的错误位置的查找数据。查找数据是索引错误位置数据的压缩形式（200）。

7. 发明申请

WO2008009300A1 SCHEDULING WIRELESS COMMUNICATION 审中-公开
标题翻译：调度无线通信
公开(公告)号：WO2008009300A1
公开(公告)日：2008-01-24
申请号：PCT/EP2006/007054
申请日：2006-07-18
申请人： FREESCALE SEMICONDUCTOR, INC. , LIN, Bo , ROUWET, Wim, J.
发明人： LIN, Bo , ROUWET, Wim, J.
IPC分类号： H04L12/56
CPC分类号： H04L47/2416 , H04L47/14 , H04L47/2441 , H04L47/32 , H04L47/50 , H04L47/527 , H04L47/564 , H04L47/6225 , H04L47/626
摘要： A method of scheduling wireless communication for one or more data flows, wherein, for each data flow, there is: a corresponding queue (200) to store data of that data flow; one or more quality-of-service parameters associated with that data flow; and a flow type associated with that data flow, there being a plurality of possible flow types; characterised in that the method comprises, during each time frame of a sequence of time frames, the steps of: maintaining (S400), for each of the plurality of possible flow types, a queue list (300) that identifies the queues corresponding to data flows of that flow type; and processing the queue lists in a predetermined order, in which processing a queue list comprises, for each queue identified in that queue list, attempting to schedule (S406, S410, S422, S430, S436, S440, S444) the communication of data stored on that queue during a current time frame in dependence upon the one or more quality-of-service parameters associated with the corresponding data flow and an amount of bandwidth available for the wireless communication during the current time frame.
摘要翻译：一种为一个或多个数据流调度无线通信的方法，其中对于每个数据流，存在：存储该数据流的数据的相应队列（200）; 与该数据流相关联的一个或多个服务质量参数; 以及与该数据流相关联的流类型，存在多个可能的流类型; 其特征在于，所述方法包括：在时间序列序列的每个时间帧期间，为所述多个可能的流类型中的每一个维护（S400）识别对应于数据的队列的队列列表（300）流量类型; 并且以预定顺序处理队列列表，其中处理队列列表包括对于在该队列列表中识别的每个队列，尝试调度（S406，S410，S422，S430，S436，S440，S444）存储的数据的通信在当前时间帧内，根据与当前时间帧相关联的一个或多个与相应数据流相关联的服务质量参数和可用于无线通信的带宽量在当前时间帧内。

8. 发明申请

WO2007003231A1 VECTOR CRC COMPUTATION ON DSP 审中-公开
标题翻译： DSP上的矢量CRC计算
公开(公告)号：WO2007003231A1
公开(公告)日：2007-01-11
申请号：PCT/EP2005/053119
申请日：2005-06-30
申请人： FREESCALE SEMICONDUCTOR, INC , LIN, Bo
发明人： LIN, Bo
IPC分类号： H03M13/09
CPC分类号： H03M13/091 , H03M13/6569
摘要： A method of generating Cyclic Redundancy Checking codes based upon an N-bit binary string (200) comprises initially reducing the N-bit binary string (20C into a compressed string of bits (B', B'', B''') using a compression look-up table (202, 204). In a vector, subblocks are reduced in parallel by parallel table look-ups using the same table. The compressed string of bits (B', B''') is congruent with the N-bit binary string (200) and so share a same CRC code. Using the compressed string of bits, a conventional CRC generation technique employed to generate the CRC code. For processing on a SIMD vector DSP.
摘要翻译：一种基于N位二进制串（200）产生循环冗余校验码的方法包括：首先使用以下方式将N位二进制串（20C）减少为压缩的比特串（B'，B“，B”'）压缩查找表（202,204），在向量中，使用相同的表，通过并行表查找并行地减少子块，压缩的位串（B'，B“'）与 N位二进制串（200）等共享相同的CRC码，使用压缩的比特串，用于生成CRC码的常规CRC生成技术，用于在SIMD向量DSP上进行处理。

9. 发明申请

WO2007003230A1 ENCRYPTION APPARATUS AND METHOD THEREFOR 审中-公开
标题翻译：加密设备及其方法
公开(公告)号：WO2007003230A1
公开(公告)日：2007-01-11
申请号：PCT/EP2005/053118
申请日：2005-06-30
申请人： FREESCALE SEMICONDUCTOR, INC , LIN, Bo
发明人： LIN, Bo
IPC分类号： H04L9/06 , H04L9/00
CPC分类号： H04L9/0625 , H04L2209/12 , H04L2209/24
摘要： A modified implementation of the Kasumi algorithm executes on a 32-bit processor (100) using full 32-bit operations. The implementation comprises a series of four rounds (202, 204, 206, 208), each round (202, 204, 206, 208) including an intermediate sub-function executed between two executions of an FL sub-function (300). The intermediate sub-function is functionally equivalent to two consecutive 16-bit FO sub- functions.
摘要翻译： Kasumi算法的修改实现在32位处理器（100）上执行，使用完整的32位操作。该实现包括一系列四轮（202,204,206,208），每轮（202,204,206,208）包括在FL子功能（300）的两次执行之间执行的中间子功能。中间子功能在功能上等同于两个连续的16位FO子功能。

10. 发明申请

WO2010095004A1 PRIORITY SEARCH TREES 审中-公开
标题翻译：优先搜索
公开(公告)号：WO2010095004A1
公开(公告)日：2010-08-26
申请号：PCT/IB2009/050721
申请日：2009-02-23
申请人： FREESCALE SEMICONDUCTOR, INC. , LIN, Bo , ROUWET, Wim
发明人： LIN, Bo , ROUWET, Wim
IPC分类号： G06F17/30 , G06F17/00
CPC分类号： G06F17/30961
摘要： An apparatus (100) arranged to implement a priority search tree to represent a plurality of data elements, the apparatus comprising: a memory (102); and a processor (104) comprising: a storage unit (110) for storing in the memory (100) for each of said data elements a corresponding data point (200) for the priority search tree, said the data point (200) having a first component value and a second component value; a tree-processing module (112) for performing at least one function operation on the data points (200), the at least one function operation involving using a comparison module (114) to perform a comparison operation to determine the relative positions of a first data point (200) and a second data point (200) in an ordering for the data points (200), the comparison operation comprising one of: (i) determining the relative positions of a first data point (200) and a second data point (200) based on a comparison of the respective first component values of the first and second data points (200) and, if the first component value of the first data point (200) equals the first component value of the second data point (200), based on a comparison of the respective second component values of the first and second data points (200); or (ii) determining the relative positions of a first data point (200) and a second data point (200) based on a comparison of the respective second component values of the first and second data points (200) and, if the second component value of the first data point (200) equals the second component value of the second data point (200), based on a comparison of the respective first component values of the first and second data points (200).
摘要翻译：一种被设置为实现优先搜索树以表示多个数据元素的装置（100），所述装置包括：存储器（102）; 以及处理器（104），包括：存储单元（110），用于将每个所述数据元素存储在所述存储器（100）中，所述数据点（200）用于所述优先级搜索树，所述数据点（200）具有第一分量值和第二分量值; 用于对所述数据点（200）执行至少一个功能操作的树处理模块（112），所述至少一个功能操作涉及使用比较模块（114）执行比较操作，以确定第一数据点（200）和第二数据点（200），所述比较操作包括以下之一：（i）确定第一数据点（200）和第二数据（200）的相对位置（200）的第一分量值与第一数据点（200）的第一分量值等于第二数据点（200）的第一分量值 200），基于第一和第二数据点（200）的各个第二分量值的比较; 或者（ii）基于第一和第二数据点（200）的相应第二分量值的比较来确定第一数据点（200）和第二数据点（200）的相对位置，如果第二分量基于第一和第二数据点（200）的各个第一分量值的比较，第一数据点（200）的值等于第二数据点（200）的第二分量值。

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