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    • 3. 发明申请
    • METHOD AND APPARATUS FOR CARRYING OUT THE CONTROLLED HEATING OF TISSUE IN THE REGION OF DERMIS
    • 在德米尔斯地区实施组织控制加热的方法和装置
    • WO2008051411A2
    • 2008-05-02
    • PCT/US2007022130
    • 2007-10-16
    • APSARA MEDICAL CORPEGGERS PHILIP EEGGERS ANDREW REGGERS ERIC A
    • EGGERS PHILIP EEGGERS ANDREW REGGERS ERIC A
    • A61F7/12
    • A61B18/082A61B2017/00747A61F2007/126
    • Implant apparatus and method for effecting a controlled heating of tissue within the region of dermis of skin. The heater implants are configured with a thermally insulative generally flat support functioning as a thermal barrier. One surface of this thermal barrier carries one or more polymerically encapsulated heater resistor segments with a lead assemblage exhibiting a 4-point topology. Each of the encapsulated heater segments may be thermally associated with a metal thermal spreader dimensioned in correspondence with and aligned with the heater segments. The implants are located within heating channels at the interface between skin dermis and the next adjacent subcutaneous tissue layer such that the heat spreaders are contactable with the lower region of dermis. During therapy a conformal heat sink is positioned against the skin above the implants and a slight tamponade is applied through the heat sink to assure a proper form of conduction heat transfer. An adjuvant may be employed to infiltrate dermis to significantly lower the thermal threshold transition temperature for dermis or dermis component shrinkage. The method and apparatus also may be employed in the treatment of capillary malformation (port wine stain).
    • 用于在皮肤真皮区域内进行组织受控加热的植入装置和方法。 加热器植入物配置有用作热障的热绝缘的大体平坦的支撑。 该热障的一个表面承载一个或多个聚合物密封的加热电阻器段,其具有呈现4点拓扑的引线组合。 每个封装的加热器段可以与金属散热器热关联,金属散热器的尺寸与加热器段对应并对齐。 植入物位于皮肤真皮和下一个相邻的皮下组织层之间的界面处的加热通道内,使得散热器可与真皮的下部区域接触。 在治疗期间,保形散热器抵靠植入物上方的皮肤定位,并且通过散热器施加轻微的填塞以确保适当形式的传导热传递。 可以使用佐剂来渗透真皮以显着降低真皮或真皮成分收缩的热阈值转变温度。 该方法和装置也可用于治疗毛细血管畸形(葡萄酒葡萄酒渍)。