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1. 发明申请

WO2008112135A2 METHOD AND APARATUS FOR SPECTROSCOPIC TISSUE ANALYTE MEASUREMENT 审中-公开
标题翻译：方法和APARATUS用于光谱组织分析仪测量
公开(公告)号：WO2008112135A2
公开(公告)日：2008-09-18
申请号：PCT/US2008/003014
申请日：2008-03-06
申请人： NELLCOR PURITAN BENNETT LLC , BAKER JR., Clark R. , DURR, Nicholas J. , MOGRI, Murtaza , HOARAU, Carine , OSTROWSKI, Rafael , DEBRECZENY, Martin P.
发明人： BAKER JR., Clark R. , DURR, Nicholas J. , MOGRI, Murtaza , HOARAU, Carine , OSTROWSKI, Rafael , DEBRECZENY, Martin P.
CPC分类号： A61B5/0059 , A61B5/4869 , A61B5/4878
摘要： Methods and systems for calculating body fluid metrics are provided. In accordance with an exemplary embodiment of the present technique, there is provided a method (50) for calculating body fluid metrics by acquiring an absorbance spectrum of a subject's tissue over a range of near-infrared light (56), performing a multi-linear regression of the absorbance spectrum of the subject's tissue in relation to absorbance spectra of tissue constituents (60), and calculating body fluid metrics based on the results of the multi-linear regression (66). A system (20) is provided having a sensor (24) for emitting the light into the subject's tissue and detecting reflected, scattered, or transmitted light, a spectrometer (40) for processing the detected light and generating the absorbance spectrum of the subject's tissue, memory (44) for storing absorbance spectra of the tissue constituents and a multi-linear regression model, and a processor (42) for performing the multi-linear regression and calculating the body fluid metrics.
摘要翻译：提供了用于计算体液量度的方法和系统。根据本技术的示例性实施例，提供了一种用于通过在近红外光范围（56）获取受试者组织的吸收光谱来计算体液量度的方法（50），执行多线性相对于组织成分的吸收光谱，对受试者组织的吸收光谱进行回归（60），并且基于多线性回归的结果计算体液量度（66）。一种系统（20），其具有传感器（24），用于将光发射到被检体的组织中并检测反射的，散射的或透射的光;光谱仪（40），用于处理检测到的光并产生受检者组织的吸收光谱，用于存储组织成分的吸收光谱的记忆（44）和多线性回归模型，以及用于执行多线性回归并计算体液量度的处理器（42）。

2. 发明申请

WO2008039424A2 CARBON DIOXIDE DETECTOR HAVING BOROSILICATE SUBSTRATE 审中-公开
标题翻译：含有硼硅酸盐基质的二氧化碳检测器
公开(公告)号：WO2008039424A2
公开(公告)日：2008-04-03
申请号：PCT/US2007/020616
申请日：2007-09-24
申请人： NELLCOR PURITAN BENNETT LLC , OSTROWSKI, Rafael , DEBRECZENY, Martin, P.
发明人： OSTROWSKI, Rafael , DEBRECZENY, Martin, P.
CPC分类号： G01N31/223 , A61M16/0084 , A61M16/08 , A61M16/0816 , A61M16/0825 , A61M16/085 , A61M2016/0413 , A61M2230/432 , G01N21/78
摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.
摘要翻译：本公开涉及具有硼硅酸盐基材的二氧化碳检测器。它也可以具有设置在硼硅酸盐基质上的二氧化碳响应指示剂溶液。二氧化碳检测器可以是二氧化碳检测器系统的一部分，二氧化碳检测器系统还包括可操作地连接到壳体以允许空气到达二氧化碳检测器的进气口。二氧化碳检测器可以包括设置在硼硅酸盐基底上的硼硅酸盐基底和二氧化碳响应指示剂溶液。该检测器可以是另一个系统的一部分，例如复苏系统。检测器可以通过用二氧化碳响应指示剂溶液润湿硼硅酸盐基质并干燥指示剂溶液以固定它并形成干燥的二氧化碳检测器来制备。通过将检测器暴露于样品，它可用于检测空气样品中二氧化碳的浓度。

3. 发明申请

WO2008039423A2 CARBON DIOXIDE DETECTOR HAVING BOROSILICATE SUBSTRATE 审中-公开
标题翻译：具有硼硅酸盐基底的二氧化碳探测器
公开(公告)号：WO2008039423A2
公开(公告)日：2008-04-03
申请号：PCT/US2007/020615
申请日：2007-09-24
申请人： NELLCOR PURITAN BENNETT LLC , OSTROWSKI, Rafael , DEBRECZENY, Martin, P.
发明人： OSTROWSKI, Rafael , DEBRECZENY, Martin, P.
IPC分类号： A61M16/08
CPC分类号： G01N31/223 , A61M16/0084 , A61M16/08 , A61M16/0816 , A61M16/0825 , A61M16/085 , A61M2016/0413 , A61M2230/432 , G01N21/78
摘要： The present disclosure relates to a carbon dioxide detector having a borosilicate substrate. It may also have a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. The carbon dioxide detector may be part of a carbon dioxide detector system also including an air intake operably connected to the housing to allow air to reach the carbon dioxide detector. The carbon dioxide detector may include a borosilicate substrate and a carbon dioxide responsive indicator solution disposed on the borosilicate substrate. This detector may be part of a further system, such as a resuscitation system. The detector may be made by wetting a borosilicate substrate with a carbon dioxide responsive indicator solution and drying the indicator solution to immobilize it and form a dried carbon dioxide detector. It may be used to detect the concentration of carbon dioxide in an air sample by exposing the detector to the sample.
摘要翻译：本发明涉及具有硼硅酸盐基质的二氧化碳检测器。也可以在硼硅酸盐基材上设置二氧化碳响应指示剂溶液。二氧化碳检测器可以是二氧化碳检测器系统的一部分，其还包括可操作地连接到壳体的空气进气口，以允许空气到达二氧化碳检测器。二氧化碳检测器可以包括硼硅酸盐底物和设置在硼硅酸盐衬底上的二氧化碳响应指示剂溶液。该检测器可以是另一系统的一部分，例如复苏系统。检测器可以通过用二氧化碳响应指示剂溶液润湿硼硅酸盐底物并干燥指示剂溶液以使其固化并形成干燥的二氧化碳检测器来制备。它可以用于通过将检测器暴露于样品来检测空气样品中二氧化碳的浓度。

4. 发明申请

WO2008039425A2 CARBOND-DIOXIDE-SENSING AIRWAY PRODUCTS AND TECHNIQUE FOR USING THE SAME 审中-公开
标题翻译：二氧化碳感应式航空母舰产品及其使用技术
公开(公告)号：WO2008039425A2
公开(公告)日：2008-04-03
申请号：PCT/US2007/020619
申请日：2007-09-24
申请人： NELLCOR PURITAN BENNETT LLC , BAKER, Clark, R. , MECCA, Roger , O'NEIL, Michael, P. , OSTROWSKI, Rafael
发明人： BAKER, Clark, R. , MECCA, Roger , O'NEIL, Michael, P. , OSTROWSKI, Rafael
IPC分类号： A61M16/04 , A61M16/01 , A61B5/083
CPC分类号： A61B5/091 , A61B5/0836 , A61B5/087 , A61B5/412 , A61M16/0057 , A61M16/04 , A61M16/0415 , A61M16/042 , A61M16/0434 , A61M16/0443 , A61M16/0459 , A61M16/0475 , A61M16/0486 , A61M16/08 , A61M2016/0413 , A61M2016/103 , A61M2230/40 , A61M2230/432
摘要： An airway device is provided that may track the flow of respiratory gases through the device with sensing elements at a plurality of locations along the gas flow path of the device. Such a device may be useful for assessing a variety of clinical states, for adjusting patient ventilator settings, or for determining whether or not an airway device has been properly inserted into a patient airway.
摘要翻译：提供了一种气道装置，其可以沿着装置的气体流动路径沿着多个位置跟踪具有感测元件的通过装置的呼吸气体的流动。这样的装置可用于评估各种临床状态，用于调节患者呼吸机设置，或用于确定气道装置是否已被正确地插入到患者气道中。

5. 发明申请

WO2008039412A2 CARBON DIOXIDE-SENSING AIRWAY PRODUCTS AND TECHNIQUE FOR USING THE SAME 审中-公开
标题翻译：二氧化碳感应式航空母舰产品及其使用技术
公开(公告)号：WO2008039412A2
公开(公告)日：2008-04-03
申请号：PCT/US2007/020587
申请日：2007-09-24
申请人： NELLCOR PURITAN BENNETT LLC , BAKER JR., Clark R. , MECCA, Roger , O'NEIL, Michael P. , OSTROWSKI, Rafael
发明人： BAKER JR., Clark R. , MECCA, Roger , O'NEIL, Michael P. , OSTROWSKI, Rafael
IPC分类号： A61M16/04 , A61M16/01 , A61B5/083
CPC分类号： A61B5/091 , A61B5/0836 , A61B5/087 , A61B5/412 , A61M16/0057 , A61M16/04 , A61M16/0415 , A61M16/042 , A61M16/0434 , A61M16/0443 , A61M16/0459 , A61M16/0475 , A61M16/0486 , A61M16/08 , A61M2016/0413 , A61M2016/103 , A61M2230/40 , A61M2230/432
摘要： An airway device is provided that may track the flow of respiratory gases through the device with sensing elements at a plurality of locations along the gas flow path of the device. Such a device may be useful for assessing a variety of clinical states, for adjusting patient ventilator settings, or for determining whether or not an airway device has been properly inserted into a patient airway.
摘要翻译：提供了一种气道装置，其可以沿着装置的气体流动路径沿着多个位置跟踪具有感测元件的通过装置的呼吸气体的流动。这样的装置可用于评估各种临床状态，用于调节患者呼吸机设置，或用于确定气道装置是否已被正确地插入到患者气道中。

6. 发明申请

WO2008039328A1 MEDICAL SENSOR AND TECHNIQUE FOR USING THE SAME 审中-公开
标题翻译：医疗传感器及其使用技术
公开(公告)号：WO2008039328A1
公开(公告)日：2008-04-03
申请号：PCT/US2007/020235
申请日：2007-09-18
申请人： NELLCOR PURITAN BENNETT LLC , OSTROWSKI, Rafael
发明人： OSTROWSKI, Rafael
IPC分类号： A61B5/00
CPC分类号： A61B5/1459 , A61B5/0059 , A61B5/14552 , A61B5/441 , A61B5/6848 , A61B5/685
摘要： A sensor 10 is provided that is appropriate for optical detection of dissolved carbon dioxide. Such a sensor 10 may be used for transcutaneous detection of carbon dioxide in the tissue. Alternatively, such sensors 10 may be inserted into the tissue. Detection of dissolved carbon dioxide in the tissue may serve as a useful clinical marker for physicians.
摘要翻译：提供适于光学检测溶解二氧化碳的传感器10。这种传感器10可用于组织中二氧化碳的经皮检测。或者，这样的传感器10可以插入到组织中。组织中溶解的二氧化碳的检测可作为医生的有用的临床标志物。

7. 发明申请

WO2007061754A1 METHOD FOR EVALUATING EXTRACELLULAR WATER CONCENTRATION IN TISSUE 审中-公开
标题翻译：用于评估组织中细胞外水分浓度的方法
公开(公告)号：WO2007061754A1
公开(公告)日：2007-05-31
申请号：PCT/US2006/044514
申请日：2006-11-16
申请人： NELLCOR PURITAN BENNETT INCORPORATED , BAKER, Clark, R., Jr. , SCHMITT, Joseph , CAMPBELL, Shannon, E. , DURR, Nick , HOARAU, Carine , OSTROWSKI, Rafael , DEBRECZENY, Martin
发明人： BAKER, Clark, R., Jr. , SCHMITT, Joseph , CAMPBELL, Shannon, E. , DURR, Nick , HOARAU, Carine , OSTROWSKI, Rafael , DEBRECZENY, Martin
IPC分类号： G01N21/27 , G01N21/35 , A61B5/00
CPC分类号： G01N21/359 , A61B5/0059 , A61B5/0537 , A61B5/4869 , G01N21/274
摘要： The present disclosure provides systems, devices, and/or methods for assessing body fluid-related metrics and/or changes therein. The disclosure further provides systems, devices, and/or methods for correlating body fluid-related metrics in a particular tissue with the corresponding whole-body metric. The disclosure also provides, systems, devices, and/or methods for assessment of such metrics to facilitate diagnosis and/or therapeutic interventions related to maintaining and/or restoring body fluid balance.
摘要翻译：本公开提供了用于评估体液相关度量和/或其变化的系统，装置和/或方法。本公开进一步提供用于将特定组织中的体液相关度量与相应的全身度量相关联的系统，装置和/或方法。本公开还提供了用于评估这些指标的系统，装置和/或方法，以便于与维持和/或恢复体液平衡有关的诊断和/或治疗干预。

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