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1. 发明申请

WO2008073573A2 METHOD AND APPARATUS FOR ALERTING NODES OF A MALICIOUS NODE IN A MOBILE AD-HOC COMMUNICATION SYSTEM 审中-公开
标题翻译：用于在移动通信系统中警告恶意节点的方法和装置
公开(公告)号：WO2008073573A2
公开(公告)日：2008-06-19
申请号：PCT/US2007081713
申请日：2007-10-18
申请人： MOTOROLA INC , NAHRSTEDT KLARA , LEE WHAY CHIOU , HE WENBO , HUANG YING
发明人： HE WENBO , HUANG YING
IPC分类号： G06F15/16
CPC分类号： H04L63/1416 , H04W12/12 , H04W84/18
摘要： A method and apparatus for alerting nodes of a malicious node in a mobile ad-hoc communication system is provided herein. Particularly, a method and apparatus for distributing an alert message to nodes surrounding a recently discovered malicious node is provided. This alert technique further leverages mobility to distribute the alert message to a large majority of nodes in the ad hoc wireless network within a reasonable amount of time.
摘要翻译：本文提供了用于在移动自组织通信系统中警告恶意节点的节点的方法和装置。特别地，提供了用于向最近发现的恶意节点周围的节点分发警报消息的方法和装置。该警报技术进一步利用移动性在合理的时间内将警报消息分发到自组织无线网络中的大多数节点。

2. 发明申请

WO2006138265A3 HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS, PREPARATION AND USE THEREOF 审中-公开
标题翻译：杂环蛋白质蛋白酶抑制剂，其制备和使用
公开(公告)号：WO2006138265A3
公开(公告)日：2007-03-01
申请号：PCT/US2006022919
申请日：2006-06-12
申请人： SCHERING CORP , PHARMACOPEIA DRUG DISCOVERY , STAMFORD ANDREW , LI GUOQING , GREENLEE WILLIAM J , ZHU ZHAONING , MCKITTRICK BRIAN , MAZZOLA ROBERT , HUANG YING , GUO TAO , LE THUY X H , QIAN GANG , SHAO YUEFEI
发明人： STAMFORD ANDREW , LI GUOQING , GREENLEE WILLIAM J , ZHU ZHAONING , MCKITTRICK BRIAN , MAZZOLA ROBERT , HUANG YING , GUO TAO , LE THUY X H , QIAN GANG , SHAO YUEFEI
IPC分类号： A61K31/519 , A61K31/4035 , A61P9/00 , A61P25/28 , A61P31/18 , A61P33/00 , C07D487/04
CPC分类号： C07D471/04 , C07D209/44 , C07D487/04
摘要： Disclosed are compounds of the formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein Q, T, U, Y, Z, ring A and R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 6 , R 7 and R 7' are as defined in the specification; pharmaceutical compositions comprising the compounds of formula I and the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases.
摘要翻译：公开了式（I）化合物或其立体异构体，互变异构体或其药学上可接受的盐或溶剂化物，其中Q，T，U，Y，Z，环A和R，R 1，R R 2，R 3，R 4，R 5，R 6，R 6，R 4， 7＆lt; 6＆gt;和＆lt; 7＆gt;和＆lt; 7＆gt;是如说明书中所定义的; 包含式I化合物的药物组合物和抑制天冬氨酰蛋白酶的方法，特别是治疗心血管疾病，认知和神经变性疾病的方法。

3. 发明申请

WO2007070592A9 THREE DIMENSIONAL DIELECTROPHORECTIC SEPARATOR AND METHODS OF USE 审中-公开
标题翻译：三维电化学分离器及其使用方法
公开(公告)号：WO2007070592A9
公开(公告)日：2007-08-16
申请号：PCT/US2006047576
申请日：2006-12-13
申请人： NANOGEN INC , HODKO DALIBOR , HUANG YING , SMOLKO DANIEL
发明人： HODKO DALIBOR , HUANG YING , SMOLKO DANIEL
CPC分类号： G01N27/447 , B03C5/005 , B03C5/026
摘要： Devices and methods for performing separation of cell particles by dielectrophoresis in three dimensions. In one embodiment the device comprises a flow chamber having microfabricated chip with a plurality of vertical and horizontal electrodes, which may be coated with a protective layer to prevent direct contact between any electrode and a sample. The horizontal electrodes are in electrical communication with a DC or an AC power source, while the vertical electrodes are in electrical communication with an AC power source.
摘要翻译：用于通过三维介电泳进行细胞颗粒分离的装置和方法。在一个实施例中，所述装置包括具有微制造芯片的流动室，所述微制造芯片具有多个垂直和水平电极，所述电极可以涂覆有保护层以防止任何电极和样品之间的直接接触。水平电极与DC或AC电源电连通，而垂直电极与AC电源电连通。

4. 发明申请

WO2012092629A3 METHODS, CELLS, AND SYSTEMS FOR INCORPORATING NON-CANONICAL AMINO ACIDS INTO PROTEINS 审中-公开
标题翻译：将非经典氨基酸掺入蛋白质的方法，细胞和系统
公开(公告)号：WO2012092629A3
公开(公告)日：2014-04-10
申请号：PCT/US2012022054
申请日：2012-01-20
申请人： WATERSTONE PHARMACEUTICALS , LIU WENSHE , HUANG YING
发明人： LIU WENSHE , HUANG YING
IPC分类号： C12P21/06 , C12N15/00 , C12N15/74 , C12Q1/48 , G01N33/569
CPC分类号： C12N15/67
摘要： The present disclosure pertains to methods of incorporating one or more non-canonical amino acids into a protein during a translation of the protein in bacterial cells. The present disclosure also pertains to methods of incorporating one or more non-canonical amino acids into a protein during an in vitro translation of the protein. In additional embodiments, the present disclosure pertains to isolated bacterial cells and in vitro translation systems (e.g., cell-free extract systems) for incorporating one or more non-canonical amino acids into a protein during a translation of the protein.
摘要翻译：本公开涉及在蛋白质在细菌细胞中翻译期间将一种或多种非标准氨基酸掺入蛋白质的方法。本公开还涉及在体外翻译蛋白质期间将一种或多种非标准氨基酸掺入蛋白质的方法。在另外的实施方案中，本公开涉及在翻译蛋白质期间将一种或多种非标准氨基酸掺入蛋白质的分离的细菌细胞和体外翻译系统（例如，无细胞提取系统）。

5. 发明申请

WO2006066153A3 ACTINOMADURA CHROMOPROTEIN, APOPROTEIN, AND GENE CLUSTER 审中-公开
标题翻译： ACTINOMADURA CHROMOPROTEIN，APOPROTEIN和GENE CLUSTER
公开(公告)号：WO2006066153A3
公开(公告)日：2007-12-13
申请号：PCT/US2005045818
申请日：2005-12-16
申请人： WYETH CORP , HALTLI BRADLEY , HE HAIYIN , HUANG YING , RABINDRAN SRIDHAR KRISHNA , WU JIANG , HE MIN
发明人： HALTLI BRADLEY , HE HAIYIN , HUANG YING , RABINDRAN SRIDHAR KRISHNA , WU JIANG , HE MIN
IPC分类号： C07K14/195
CPC分类号： C12N15/52
摘要： The present invention provides a chromoprotein produced by Actinomadura sp. 21G792, as well as amino acid and nucleic acid sequences of the apoprotein component of the chromoprotein and of components of the biosynthetic pathway for the chromophore. The present invention is useful for developing pharmaceutical and treating diseases such as cancer or bacterial infections.
摘要翻译：本发明提供了由放线菌属（Actinomadura） 21G792，以及发色团的脱辅基蛋白组分的氨基酸和核酸序列以及发色团的生物合成途径的组分。本发明可用于开发药物和治疗诸如癌症或细菌感染的疾病。

6. 发明申请

WO2005116009B1 SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS 审中-公开
标题翻译：作为PDE4抑制剂有用的取代的2-喹啉氧化物
公开(公告)号：WO2005116009B1
公开(公告)日：2006-01-26
申请号：PCT/US2005017134
申请日：2005-05-16
申请人： SCHERING CORP , KUANG RONGZE , BLYTHIN DAVID , SHIH NENG-YANG , SHUE HO-JANE , CHEN XIAO , CAO JIANHUA , GU DANLIN , HUANG YING , SCHWERDT JOHN H , TING PAULINE C , WONG SHING-CHUN , XIAO LI
发明人： KUANG RONGZE , BLYTHIN DAVID , SHIH NENG-YANG , SHUE HO-JANE , CHEN XIAO , CAO JIANHUA , GU DANLIN , HUANG YING , SCHWERDT JOHN H , TING PAULINE C , WONG SHING-CHUN , XIAO LI
IPC分类号： A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/498 , A61K31/501 , A61K31/506 , A61K31/519 , C07D401/04 , C07D405/04 , C07D405/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
CPC分类号： C07D405/14 , C07D401/04 , C07D405/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14
摘要： The invention claims compounds of the: (formula I); wherein: (formula II) is a 5-membered heteroaryl; X is S or O; R
摘要翻译：本发明要求下列化合物：（式I）; 其中：（式II）是5元杂芳基; X为S或O; [R

7. 发明申请

WO2005016876A3 CYCLIC AMINE BACE-1 INHIBITORS HAVING A BENZAMIDE SUBSTITUENT 审中-公开
标题翻译：具有苯甲酸替代物的循环胺BACE-1抑制剂
公开(公告)号：WO2005016876A3
公开(公告)日：2005-09-22
申请号：PCT/US2004025018
申请日：2004-08-04
申请人： SCHERING CORP , PHARMACOPEIA DRUG DISCOVERY , CUMMING JARED N , ISERLOH ULRICH , STAMFORD ANDREW , STRICKLAND COREY , VOIGT JOHANNES H , WU YUSHENG , HUANG YING , XIA YAN , CHACKALAMANNIL SAMUEL , GUO TAO , HOBBS DOUGLAS W , LE THUY X H , LOWRIE JEFFREY F , SAIONZ KURT W , BABU SURESH D
发明人： CUMMING JARED N , ISERLOH ULRICH , STAMFORD ANDREW , STRICKLAND COREY , VOIGT JOHANNES H , WU YUSHENG , HUANG YING , XIA YAN , CHACKALAMANNIL SAMUEL , GUO TAO , HOBBS DOUGLAS W , LE THUY X H , LOWRIE JEFFREY F , SAIONZ KURT W , BABU SURESH D
IPC分类号： A61K31/55 , A61K31/553 , A61K31/554 , A61K31/675 , C07D207/09 , C07D211/26 , C07D217/18 , C07D241/04 , C07D243/08 , C07D401/06 , C07D403/12 , C07D403/14 , C07D413/06 , C07F9/38 , A61K31/40 , A61K31/47 , A61K31/495 , A61K31/5355 , A61K33/42
CPC分类号： C07D243/08 , C07D205/04 , C07D207/08 , C07D207/09 , C07D207/12 , C07D207/26 , C07D209/52 , C07D211/26 , C07D211/46 , C07D217/18 , C07D233/32 , C07D241/04 , C07D241/08 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/12 , C07D403/14 , C07D409/06 , C07D409/12 , C07D413/06
摘要： Disclosed are compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R is-C(O)-N(R )(R ) or and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of treating cognitive or neurodegenerative diseases such as Alzheimer's disease. Also disclosed are pharmaceutical compositions and methods of treating cognitive or neurodegenerative diseases comprising the compounds of formula I in combination with a beta-secretase inhibitor other than those of formula I, an HMG-CoA reductase inhibitor, a gamma-secretase inhibitor, a non-steroidal anti-inflammatory agent, and N-methyl-D-aspartate receptor antagonist, a cholinesterase inhibitor or an anti-amyloid antibody.
摘要翻译：公开了下式的化合物或其药学上可接受的盐或溶剂化物，其中R是-C（O）-N（R 27）（R 28）），其余的变量如说明书中所定义。还公开了包含式I化合物的药物组合物。还公开了治疗认知或神经变性疾病如阿尔茨海默病的方法。还公开了治疗认知或神经变性疾病的药物组合物和方法，其包含式I化合物与除式I以外的β-分泌酶抑制剂，HMG-CoA还原酶抑制剂，γ-分泌酶抑制剂，甾族抗炎剂和N-甲基-D-天冬氨酸受体拮抗剂，胆碱酯酶抑制剂或抗淀粉样蛋白抗体。

8. 发明申请

WO2004092397A3 TMPRSS2 REGULATORY SEQUENCES AND USES THEREOF 审中-公开
标题翻译： TMPRSS2法规序列及其用途
公开(公告)号：WO2004092397A3
公开(公告)日：2005-02-10
申请号：PCT/US2004011623
申请日：2004-04-15
申请人： NOVARTIS AG , IRM LLC , HALLENBECK PAUL , HAMPTON GARRET , HAY CARL , HUANG YING , JAKUBCZAK JOHN
发明人： HALLENBECK PAUL , HAMPTON GARRET , HAY CARL , HUANG YING , JAKUBCZAK JOHN
IPC分类号： A01N63/00 , A61K48/00 , C07H21/04 , C07K14/47 , C12N5/00 , C12N15/63 , C12N15/85 , C12N15/861 , C12Q20060101
CPC分类号： C07K14/4702 , C12N15/85 , C12N15/86 , C12N2710/10332 , C12N2710/10343 , C12N2840/007
摘要： TMPRSS2 transcriptional regulatory sequences (TREs) are provided. TMPRSS2 TREs provide for transcriptional regulation dependent upon transcription factors that are only active in prostate cancer cells. The TMPRSS2 TREs may be used as a vehicle for introducing new genetic capability, particularly associated with cytotoxicity, for selective expression in prostate cancer cells.
摘要翻译：提供TMPRSS2转录调控序列（TRE）。 TMPRSS2 TRE提供依赖于仅在前列腺癌细胞中活跃的转录因子的转录调节。 TMPRSS2 TREs可以用作引入新的遗传能力，特别是与细胞毒性有关的载体，用于在前列腺癌细胞中选择性表达。

9. 发明申请

WO2010121440A9 MOBILE COMMUNICATION METHOD, DEVICE AND SYSTEM FOR ENSURING SERVICE CONTINUITY 审中-公开
标题翻译：移动通信方法，用于维护服务连续性的设备和系统
公开(公告)号：WO2010121440A9
公开(公告)日：2011-07-21
申请号：PCT/CN2009071468
申请日：2009-04-24
申请人： HUAWEI TECH CO LTD , HUANG YING , YANG LI
发明人： HUANG YING , YANG LI
IPC分类号： H04W76/02
CPC分类号： H04W36/0055 , H04W36/0033 , H04W76/028
摘要： A mobile communication method, a device and a system are provided by embodiments of the present invention. The mobile communication system includes a user side equipment, a first network side equipment and a second network side equipment which cover the user side equipment together. The method includes: the user side equipment sends a reconnection request message to the second network side equipment when disconnecting from the first network side equipment and detecting remote link failure (RLF); the second network side equipment tries to obtain context data of the user side equipment; if the second network side equipment fails to obtain the context data, then sends a reconnection failure message to the user side equipment; and if the second network side equipment obtains the context data successfully, then sends a reconnection acknowledge message, the user side equipment connects to the second network side equipment responding to the reconnection acknowledge message. The communication method, the device and the system can ensure service continuity of the user side equipment to the utmost extent when a cell has malfunction suddenly and fails to work normally.
摘要翻译：通过本发明的实施例提供移动通信方法，设备和系统。移动通信系统包括将用户侧设备覆盖在一起的用户侧设备，第一网络侧设备和第二网络侧设备。该方法包括：当与第一网络侧设备断开连接并检测远程链路故障（RLF）时，用户侧设备向第二网络侧设备发送重新连接请求消息; 第二网络侧设备尝试获取用户侧设备的上下文数据; 如果第二网络侧设备无法获得上下文数据，则向用户侧设备发送重连失败消息; 并且如果第二网络侧设备成功获得上下文数据，则发送重新连接确认消息，用户侧设备根据重新连接确认消息连接到第二网络侧设备。通信方法，设备和系统可以在单元突然发生故障，无法正常工作的情况下，最大限度地保证用户侧设备的业务连续性。

10. 发明申请

WO2007053623A3 METHOD AND APPARATUS FOR PERFORMING ENCRYPTION OF DATA AT REST AT A PORT OF A NETWORK DEVICE 审中-公开
标题翻译：用于在网络端口端执行数据恢复的方法和装置
公开(公告)号：WO2007053623A3
公开(公告)日：2009-05-07
申请号：PCT/US2006042477
申请日：2006-10-30
申请人： CISCO TECH INC , PARLAN JONATHAN , KLOTH RAYMOND J , HUANG YING , MAINO FABIO R , AGRAWAL PAWAN
发明人： PARLAN JONATHAN , KLOTH RAYMOND J , HUANG YING , MAINO FABIO R , AGRAWAL PAWAN
IPC分类号： H04L9/00
CPC分类号： H04L9/0897 , H04L9/0891 , H04L9/0894 , H04L9/3247 , H04L63/0428 , H04L63/0485 , H04L2209/56 , H04L2209/80
摘要： Methods and apparatus for performing encryption for data at rest at a port of a network device such as a switch are disclosed. Specifically, when data is received from a host during a write to a storage medium such as a disk, the data is encrypted by the port prior to transmitting the encrypted data to the storage medium. Similarly, when a host attempts to read data from the storage medium, the port of the network device receives the encrypted data from the storage medium, decrypts the data, and transmits the decrypted data to the host. In this manner, encryption and decryption of data at rest are supported by the port of the network device.
摘要翻译：公开了用于在诸如交换机的网络设备的端口处静止的数据执行加密的方法和装置。具体地说，当在向诸如盘的存储介质的写入期间从主机接收到数据时，在将加密数据发送到存储介质之前，数据被端口加密。类似地，当主机尝试从存储介质读取数据时，网络设备的端口从存储介质接收加密的数据，解密数据，并将解密的数据发送到主机。以这种方式，网络设备的端口支持静止数据的加密和解密。

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