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1. 发明申请

WO2010075020A2 COLLABORATIVE SEARCHING 审中-公开
标题翻译：合作搜索
公开(公告)号：WO2010075020A2
公开(公告)日：2010-07-01
申请号：PCT/US2009067822
申请日：2009-12-14
申请人： MOTOROLA INC , MOK SWEE M , ALBERTH WILLIAM P , BARR JOHN R , ENGELSMA JONATHAN R , GILLIG STEVEN F , XU XIANG
发明人： MOK SWEE M , ALBERTH WILLIAM P , BARR JOHN R , ENGELSMA JONATHAN R , GILLIG STEVEN F , XU XIANG
IPC分类号： G06F17/30 , H04B1/40
CPC分类号： G06F17/30867 , G06F17/30678 , G06F17/30702
摘要： Disclosed are techniques that allow users (102, 104, 106) to collaborate in a search. Each user (102, 104, 106) can contribute (300, 400) to an original search and to refining (304, 410) the results of the search. Preferences of all of the users (102, 104, 106) are considered (308, 402) in the search even while those preferences can be kept private. In some embodiments of the present invention, at least two users (102, 104, 106) each submit (300, 304) a search query. The multiple search queries are logically combined (306) to produce (310) one set of search results. The results can be reviewed by the users (102, 104, 106) and refined (304) if necessary. In some embodiments, a search query can be specified (400) by a single user (102, 104, 106), but the search engine takes into consideration (402) the stored preferences of multiple users (102, 104, 106) (in addition to the search query itself, of course).
摘要翻译：公开了允许用户（102,104,106）在搜索中合作的技术。每个用户（102,104,106）可以贡献（300,400）到原始搜索并且精炼（304,410）搜索结果。在搜索中考虑所有用户（102,104,106）的偏好（308,402），即使这些偏好可以保持私密。在本发明的一些实施例中，至少两个用户（102,104,106）各自提交（300,304）搜索查询。多个搜索查询在逻辑上组合（306）以产生（310）一组搜索结果。如果有必要，结果可以由用户（102,104,106）查看并且精炼（304）。在一些实施例中，搜索查询可以由单个用户（102,104,106）指定（400），但是搜索引擎考虑（402）多个用户（102,104,106）的存储的偏好（在当然，除了搜索查询本身之外）。

2. 发明申请

WO2008067355A3 ON DEMAND RADIO ACCESS TECHNOLOGY SELECTION 审中-公开
标题翻译：需求无线电访问技术选择
公开(公告)号：WO2008067355A3
公开(公告)日：2008-08-21
申请号：PCT/US2007085717
申请日：2007-11-28
申请人： MOTOROLA INC , BARR JOHN R , ESSICK RAYMOND B
发明人： BARR JOHN R , ESSICK RAYMOND B
IPC分类号： H04W48/08 , H04W48/18 , H04W68/00 , H04W76/02 , H04W88/06
CPC分类号： H04W48/18 , H04W48/08 , H04W68/00 , H04W76/02 , H04W88/06
摘要： System and method for receiving a call in a wireless device. A notification message is received o
摘要翻译：用于在无线设备中接收呼叫的系统和方法。收到通知消息o

3. 发明申请

WO2009110873A3 IMPROVED VIRAL PROTEIN QUANTIFICATION AND VACCINE QUALITY CONTROL THEREWITH 审中-公开
标题翻译：改进的病毒蛋白定量和疫苗质量控制
公开(公告)号：WO2009110873A3
公开(公告)日：2009-11-12
申请号：PCT/US2008013396
申请日：2008-12-05
申请人： GOV OF THE USA AS REPRESENTED , WILLIAMS TRACIE L , BARR JOHN R , GUO ZHU , LUNA LEAH G , DONIS RUBIN , PIRKLE JAMES L
发明人： WILLIAMS TRACIE L , BARR JOHN R , GUO ZHU , LUNA LEAH G , DONIS RUBIN , PIRKLE JAMES L
IPC分类号： G01N33/483 , G01N30/00
CPC分类号： G01N30/7233 , G01N2030/045 , G01N2030/8831 , G01N2030/8868
摘要： A process of quantifying proteins in a complex mixture is provided. The invention has utility in quantifying proteins in a complex preparation of uni- or multivalent commercial or research vaccine preparations.
摘要翻译：提供了定量复杂混合物中蛋白质的过程。本发明可用于量化单价或多价商业或研究疫苗制剂的复合制剂中的蛋白质。

4. 发明申请

WO2007041457A2 PHILANTHROPY MANAGEMENT AND METRICS SYSTEM 审中-公开
标题翻译：哲学管理与量度系统
公开(公告)号：WO2007041457A2
公开(公告)日：2007-04-12
申请号：PCT/US2006038362
申请日：2006-10-02
申请人： NEWDEA INC , BARR JOHN R , KLINKEL GREG D , SHANNON GORDON , ALTEMOSE GLENN JR , STREMLER TROY
发明人： BARR JOHN R , KLINKEL GREG D , SHANNON GORDON , ALTEMOSE GLENN JR , STREMLER TROY
IPC分类号： G07F19/00 , G06Q10/00 , G06Q40/00
CPC分类号： G06Q30/0279 , G06Q10/06 , G06Q10/10 , G06Q40/02 , G06Q40/12 , G06Q50/26
摘要： Organizations, which may be charitable organizations, may plan, implement, and report to interested on the impact their projects. Users may create and modify components, which demonstrate a relationship between, for example, a donor donation, and an effect of that donation. Users can set up, modify and allowing reporting on, for example, activities sponsored by a charitable organization, inputs into that activity which may be sponsored by donors, and results of the activity. Results can be tracked over time producing a moving picture of the impact of the activity.
摘要翻译：可能是慈善组织的组织可以对其项目的影响进行计划，实施和报告。用户可以创建和修改组件，这些组件显示了捐赠者捐赠之间的关系，以及捐赠的效果。用户可以设置，修改和允许报告，例如，由慈善组织发起的活动，可能由捐助者赞助的活动的投入以及活动的结果。随着时间的推移可以跟踪结果，从而产生活动影响的动态图像。

5. 发明申请

WO2012074683A2 DETECTION OF ADENYLATE CYCLASE 审中-公开
标题翻译：检测腺苷酸环化酶
公开(公告)号：WO2012074683A2
公开(公告)日：2012-06-07
申请号：PCT/US2011059739
申请日：2011-11-08
申请人： US GOV HEALTH & HUMAN SERV , BOYER ANNE E , LINS RENATO C , KUKLENYIK ZSUZSANNA , GALLEGOS-CANDELA MARIBEL , QUINN CONRAD P , BARR JOHN R
发明人： BOYER ANNE E , LINS RENATO C , KUKLENYIK ZSUZSANNA , GALLEGOS-CANDELA MARIBEL , QUINN CONRAD P , BARR JOHN R
CPC分类号： G01N33/56911 , C12Q1/527 , G01N2333/32 , G01N2333/988
摘要： One major problem in diagnosis methods presently available for anthrax is that these methods require several days to produce a result, are rendered unusable after antibiotic use, or are not quantifiable. The only existing treatment for anthrax requires administration soon after infection at a time when patients are exhibiting only mild flu-like symptoms. Thus, by the time a diagnosis is made a patient may be days beyond the time when treatment would be effective. The present invention reduces diagnosis time to as little as four hours providing same day identification of anthrax radically increasing the odds of delivering proper treatment and patient recovery. The rapid identification of anthrax edema factor activity exhibited by the invention is also amenable to in vivo screening protocols for the discovery and development of anthrax vaccines, anti-toxins and edema factor inhibitors. The invention isolates and concentrates edema factor and edema toxin from nearly any sample. By capitalizing on the adenylate cyclase activity of edema factor the invention amplifies output signals producing reliable detection of low concentrations of edema factor previously unachievable. The invention involves novel purification and detection techniques and substrates for rapid, reproducible, and quantitative measurements of anthrax edema factor, and other adenylate cyclases in biological samples.
摘要翻译：目前可用于炭疽的诊断方法中的一个主要问题是这些方法需要几天才能产生结果，在抗生素使用后不能使用，或不能量化。炭疽病唯一现有的治疗方法需要在感染后立即进行治疗，当时患者只出现轻微的流感样症状。因此，在进行诊断的时候，患者可以是治疗有效的时间。本发明将诊断时间缩短至少于4小时，同时提供炭疽的同一天鉴定，从而大大增加了提供适当治疗和患者恢复的几率。本发明显示的炭疽水肿因子活性的快速鉴定也适用于发现和发展炭疽疫苗，抗毒素和水肿因子抑制剂的体内筛选方案。本发明从几乎任何样品中分离并浓缩水肿因子和水肿毒素。通过利用水肿因子的腺苷酸环化酶活性，本发明放大了产生可靠检测低浓度水肿因子的输出信号，这是先前无法实现的。本发明涉及用于快速，可重复和定量测量生物样品中炭疽水肿因子和其他腺苷酸环化酶的新型纯化和检测技术和底物。

6. 发明申请

WO2007136436A3 DETECTION OF ANTHRAX PATHOGENICITY FACTORS 审中-公开
标题翻译：检测ANTHRAX致病因子
公开(公告)号：WO2007136436A3
公开(公告)日：2008-07-24
申请号：PCT/US2007004156
申请日：2007-02-15
申请人： US GOV HEALTH & HUMAN SERV , BOYER ANNE E , QUINN CONRAD P , BARR JOHN R
发明人： BOYER ANNE E , QUINN CONRAD P , BARR JOHN R
IPC分类号： C12Q1/00 , C12N9/00
CPC分类号： G01N33/56911 , G01N2333/32 , G01N2500/00
摘要： One major problem in diagnosis methods presently available for anthrax is that these methods require several days to produce a result. The only existing treatment for anthrax requires administration soon after infection at a time when patients are exhibiting only mild flu- like symptoms. Thus, a patient may be days beyond the time when treatment would be effective by the time a diagnosis is made. The present invention reduces diagnosis time to as little as four hours providing same day identification of anthrax radically increasing the odds of delivering proper treatment and patient recovery. The rapid identification of anthrax lethal factor activity exhibited by the instant invention is also amenable to in vivo screening protocols for the discovery and development of anthrax vaccines and lethal factor inhibitors. The instant invention isolates and concentrates lethal factor and lethal toxin from nearly any biological sample. By capitalizing on the endopeptidase activity of lethal factor the present invention amplifies output signals producing reliable detection of picomolar concentrations of lethal factor. The instant invention involves novel purification and detection techniques and substrates for rapid, reproducible, and quantitative measurements of anthrax lethal factor in biological samples.
摘要翻译：目前可用于炭疽的诊断方法的一个主要问题是这些方法需要几天才能产生结果。炭疽病唯一现有的治疗方法需要在感染后立即进行治疗，当时患者仅出现轻微的流感样症状。因此，患者可能是在诊断时治疗有效的时间。本发明将诊断时间缩短至少于4小时，同时提供炭疽的同一天鉴定，从而大大增加了提供适当治疗和患者恢复的几率。本发明显示的炭疽致死因子活性的快速鉴定也适用于发现和发展炭疽疫苗和致死因子抑制剂的体内筛选方案。本发明从几乎任何生物样品中分离和浓缩致死因子和致死毒素。通过利用致死因子的内肽酶活性，本发明扩增了产生对皮摩尔浓度致死因子的可靠检测的输出信号。本发明涉及用于生物样品中炭疽致死因子的快速，可重复和定量测量的新颖的纯化和检测技术和底物。

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