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1. 发明申请

WO2008061139A2 HEATING AND STERILIZING APPARATUS AND METHOD OF USING SAME 审中-公开
标题翻译：加热灭菌装置及其使用方法
公开(公告)号：WO2008061139A2
公开(公告)日：2008-05-22
申请号：PCT/US2007/084670
申请日：2007-11-14
申请人： MICROPYRETICS HEATERS INTERNATIONAL, INC. , VISSA, Ramgopal , REDDY, Ganta, S. , SEKHAR, Jainagesh, A.
发明人： VISSA, Ramgopal , REDDY, Ganta, S. , SEKHAR, Jainagesh, A.
IPC分类号： A61L2/07 , F24H1/16
CPC分类号： A61L2/07 , F24H3/0423
摘要： An apparatus (200, 300, 400) for generating superheated steam capable of reducing or eliminating microorganisms associated with an item (230) includes a gas heater (10) for heating a gas, a steam generator coupled to the gas heater (10) and having a reservoir (216, 304) for supplying water, wherein the heater (10) heats the gas such that when water is combined therewith, a mixture of superheated steam and gas capable of reducing or eliminating microorganisms is discharged from the apparatus (200, 300, 400). The generation of the steam-gas mixture may be done at one atmosphere of pressure and the mixing may be done prior to expelling the fluid from the apparatus (200, 300, 400). The apparatus (400) may be configured as a hand-held device, A method of treating an item (230) for microorganisms includes generating a superheated steam at approximately one atmosphere of pressure, directing a flow of the steam onto the item (230), and reducing or eliminating microorganisms using the steam.
摘要翻译：一种用于产生能够减少或消除与物品（230）相关联的微生物的过热蒸汽的装置（200,300,400）包括用于加热气体的气体加热器（10），耦合到所述气体加热器（10）的蒸汽发生器和具有用于供应水的储存器（216,304），其中所述加热器（10）加热气体，使得当与其组合时，过热蒸汽和能够减少或消除微生物的气体的混合物从所述设备（200， 300,400）。蒸汽 - 气体混合物的产生可以在一个压力气氛下进行，混合可以在从装置（200,300,400）排出流体之前进行。一种处理微生物物品（230）的方法包括在大约一个压力的气氛下产生一个过热蒸汽，将蒸汽流引导到物品（230）上，该装置（400）可以被配置为手持装置。，并使用蒸汽减少或消除微生物。

2. 发明申请

WO2008061137A2 APPARATUS AND METHOD FOR STERILIZING ITEMS 审中-公开
标题翻译：用于灭菌物品的装置和方法
公开(公告)号：WO2008061137A2
公开(公告)日：2008-05-22
申请号：PCT/US2007/084667
申请日：2007-11-14
申请人： MICROPYRETICS HEATERS INTERNATIONAL, INC. , REDDY, Ganta, S. , VISSA, Ramgopal , SEKHAR, Jainagesh, A.
发明人： REDDY, Ganta, S. , VISSA, Ramgopal , SEKHAR, Jainagesh, A.
IPC分类号： A61L2/07
CPC分类号： A61L2/07 , A61L2/025 , A61L2/04 , A61L2/08 , A61L2/20 , A61L2/208
摘要： A sterilizing apparatus (10, 80) includes an enclosure (18, 84) defining an interior chamber (20, 86) and a door (22) for accessing the interior chamber (20, 86). A fluid source (42, 88) communicates with the chamber (20, 86) to supply a working fluid thereto. A heater (64, 102) heats the fluid in the chamber (20, 86) and a pump (62, 82) moves the fluid in the chamber (20, 86) by the heater (64, 102). A valve (50, 150) communicates with the chamber (20, 86) and with the exterior of the chamber (20, 86) and is configured to vent the fluid in the chamber (20, 86) to the exterior at a pressure of approximately one atmosphere. Such provides superheating and concentrating of the working fluid in the chamber (20, 86). A method of sterilization includes introducing a working fluid into an interior chamber (20, 86) and circulating the fluid through at least one recirculation loop (54, 96) having a heater (64, 102) for heating the fluid to an operational temperature suitable for killing microorganisms. The method further provides venting of the fluid from the chamber (20, 86) so as to maintain the pressure at approximately one atmosphere. The method further provides for killing of very high temperature resistant microorganisms.
摘要翻译：杀菌装置（10,80）包括限定内部腔室（20,86）和用于进入内部腔室（20,86）的门（22）的外壳（18,84）。流体源（42,88）与腔室（20,86）连通以向其供应工作流体。加热器（64,102）加热腔室（20,86）中的流体，泵（62,82）通过加热器（64,102）移动腔室（20,86）中的流体。阀（50,150）与腔室（20,86）和腔室（20,86）的外部连通并且构造成将腔室（20,86）中的流体以大约一个大气。这样可以提供工作流体在腔室（20,86）中的过热和浓缩。灭菌方法包括将工作流体引入内部腔室（20,86）并使流体循环通过具有加热器（64,102）的至少一个再循环回路（54,96），用于将流体加热至适合的操作温度用于杀死微生物。该方法进一步提供流体从腔室（20,86）的排气，以将压力保持在大约一个大气压。该方法进一步提供杀灭非常耐高温的微生物。

3. 发明申请

WO2012050639A1 ANTIBIOFILM NANOPOROUS NANOSTRUCTURES AND METHOD TO PRODUCE SAME 审中-公开
标题翻译：抗生物膜纳米生物纳米结构及其生产方法
公开(公告)号：WO2012050639A1
公开(公告)日：2012-04-19
申请号：PCT/US2011/034879
申请日：2011-05-03
申请人： MICROPYRETICS HEATERS INTERNATIONAL, INC. , REDDY, Ganta, S. , SEKHAR, Jainagesh, A.
发明人： REDDY, Ganta, S. , SEKHAR, Jainagesh, A.
IPC分类号： C23C4/12 , B05D1/04 , C23C28/02 , C23C4/04
CPC分类号： C09D5/1681 , A01N25/34 , C23C4/04 , C23C4/131 , C23C26/00 , Y10T428/249921 , Y10T428/249967 , Y10T428/249969 , Y10T428/24997 , Y10T428/249979 , A01N59/16
摘要： Durable nanoporous nanostructured materials that modify, eliminate and destroy biofilms that may develop due to the presence of bacteria, fungi and other microbes and method for making the same. Such nanoporous nanostructures may be deposited as coatings on a substrate and such coatings may include at least one nanopore and a plurality of nanoparticles which adhere to the substrate and/or other particles. The nanostructure can be produced using a single-sided electrode arrangement, which is configured to produce an electrical arc or discharge at one end of an electrode and to emit the nanoparticles from the electrode, where the arc or discharge can be produced without the end of the electrode being in proximity to a grounded object. The nanoparticles form a non-porous framework which delineates any nanopores and which can be deposited as one or more layers of nanothickness. Such nanostructures may be resistant to removal from the substrate. Also described are testing methods and apparatus for the quick, accurate and simple evaluation of the efficacy of the antibiofilm properties of the nanoporous nanostructure.
摘要翻译：耐久的纳米多孔纳米结构材料，其可以修饰，消除和破坏由于细菌，真菌和其他微生物的存在而可能发展的生物膜及其制备方法。这样的纳米多孔纳米结构可以作为涂层沉积在基底上，并且这样的涂层可以包括粘附到基底和/或其它颗粒上的至少一个纳米孔和多个纳米颗粒。可以使用单面电极布置来制造纳米结构，其被配置为在电极的一端产生电弧或放电并从电极发射纳米颗粒，其中可以产生电弧或放电而不停止电极接近接地物体。纳米颗粒形成无孔框架，其描绘任何纳米孔，并且可以沉积为一层或多层纳米孔。这样的纳米结构可能抵抗从基底去除。还描述了用于快速，准确和简单地评估纳米多孔纳米结构的抗菌膜性质的功效的测试方法和装置。

4. 发明申请

WO2008136866A2 ANTIMICROBAL MATERIALS AND COATINGS 审中-公开
标题翻译：抗微生物材料和涂料
公开(公告)号：WO2008136866A2
公开(公告)日：2008-11-13
申请号：PCT/US2007/085564
申请日：2007-11-27
申请人： MICROPYRETICS HEATERS INTERNATIONAL, INC. , REDDY, Ganta, S. , SEKHAR, Jainagesh, A.
发明人： REDDY, Ganta, S. , SEKHAR, Jainagesh, A.
IPC分类号： C09D5/14 , A01N59/16 , D21H21/36
CPC分类号： D21H21/36 , A01N25/34 , A01N59/16 , C09D5/14 , C09D5/1618 , C09D5/1625 , C09D5/1681 , C09D5/1687 , Y10T428/25 , Y10T428/256 , Y10T428/257 , Y10T428/258 , Y10T428/259 , Y10T428/2982 , A01N59/00 , A01N59/20
摘要： Durable antimicrobial coatings which may be deposited on a substrate, and method and apparatus for producing them. Such coatings can include a plurality of particles which adhere to the substrate and/or other particles. The particles can be provided using a single-sided electrode arrangement, which is configured to produce an electrical arc or discharge at one end of an electrode and to emit the particles from the electrode, where the arc or discharge can be produced without the end of the electrode being in proximity to a grounded object. The particles can be provided as one or more layers of nanoscale particles having an average size of less than about 1000 nm, 800 nm, 500 nm, or 200 nm. Such coatings can have a thickness that is less than about 1000 nm, 800 nm, 500 nm, or 250 nm. Thicker coatings may also be provided. The coatings may preferably include silver, tungsten, noble metals, nonstoichiometric compounds including ceramics, other metals including rare earth metals and compounds thereof, and combinations thereof. Such coatings may be resistant to removal from the substrate and can exhibit antimicrobial properties, e.g., they may kill or inhibit growth of bacteria and other microbes.
摘要翻译：可沉积在基材上的耐久的抗微生物涂层，以及用于生产它们的方法和装置。这种涂层可以包括粘附到基底和/或其它颗粒上的多个颗粒。可以使用单面电极布置来提供颗粒，其被配置为在电极的一端产生电弧或放电并且从电极发射颗粒，其中可以产生电弧或放电而不会结束电极接近接地物体。颗粒可以作为平均尺寸小于约1000nm，800nm，500nm或200nm的一层或多层纳米尺寸颗粒提供。这种涂层可以具有小于约1000nm，800nm，500nm或250nm的厚度。也可以提供较厚的涂层。涂层可以优选包括银，钨，贵金属，包括陶瓷的非化学计量化合物，包括稀土金属的其它金属及其化合物，以及它们的组合。这样的涂层可能抵抗从底物中除去并且可以表现出抗微生物性质，例如它们可能杀死或抑制细菌和其它微生物的生长。

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