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1. 发明申请

WO2008075034A1 STORAGE COMBINATION BOILER 审中-公开
标题翻译：存储组合锅炉
公开(公告)号：WO2008075034A1
公开(公告)日：2008-06-26
申请号：PCT/GB2007/004871
申请日：2007-12-19
申请人： MICROGEN ENERGY LIMITED , CLARK, David , STEADE, David
发明人： CLARK, David , STEADE, David
IPC分类号： F24H1/00
CPC分类号： F24H1/00 , F02G2254/10 , F24H2240/04 , Y02E20/14
摘要： A storage combination (combi) boiler system and a method for providing heating, comprising: a domestic combined heat and power (dchp) unit, which provides a heat output and an electricity output; a first piping system, containing fluid which is heated by the heat output of the dchp unit; a second piping system, containing fluid which is heated by transfer of heat from the fluid in the first piping system using a heat exchanger; and a storage vessel, located within the first piping system, downstream from the heat exchanger, for receiving and storing fluid within that first piping system so as to provide a thermal store for the heat in the first piping system.
摘要翻译：一种存储组合（combi）锅炉系统和一种提供加热的方法，包括：提供热量输出和电力输出的家用热电联产单元; 第一管道系统，包含由dchp单元的热输出加热的流体; 第二管道系统，其包含通过使用热交换器从第一管道系统中的流体传递热量而被加热的流体; 以及存储容器，位于所述第一管道系统内，在所述热交换器的下游，用于在所述第一管道系统内接收和存储流体，以便为所述第一管道系统中的热提供热存储。

2. 发明申请

WO2005070893A2 AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS 审中-公开
标题翻译： AZADECALIN GLUCOCORTICOID受体调节剂
公开(公告)号：WO2005070893A2
公开(公告)日：2005-08-04
申请号：PCT/US2005/000607
申请日：2005-01-10
申请人： CORCEPT THERAPEUTICS, INC. , CLARK, Robin, D. , RAY, Nicholas, C. , BLANEY, Paul , HURLEY, Christopher , WILLIAMS, Karen , HUNT, Hazel , CLARK, David
发明人： CLARK, Robin, D. , RAY, Nicholas, C. , BLANEY, Paul , HURLEY, Christopher , WILLIAMS, Karen , HUNT, Hazel , CLARK, David
IPC分类号： C07D217/00
CPC分类号： C07D217/04 , C07D217/02 , C07D217/06 , C07D217/08 , C07D401/10 , C07D401/12 , C07D405/06 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D491/10 , C07D513/04 , C07D513/06
摘要： The present invention provides a novel class of azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
摘要翻译：本发明提供了一类新颖的氮杂环丁烷化合物和使用该化合物作为糖皮质激素受体调节剂的方法。

3. 发明申请

WO2004060509A2 FREE-SPACE (NON-TACTILE) HUMAN INTERFACE FOR INTERACTIVE MUSIC, FULL-BODY MUSICAL INSTRUMENT, AND IMMERSIVE MEDIA CONTROLLER 审中-公开
标题翻译：交互式音乐，全身音乐仪器和独立媒体控制器的自由空间（非触觉）人机界面
公开(公告)号：WO2004060509A2
公开(公告)日：2004-07-22
申请号：PCT/US2003/041798
申请日：2003-12-30
申请人： CLARK, David , GIBBON, John
发明人： CLARK, David , GIBBON, John
IPC分类号： A63F
CPC分类号： G10H1/0008 , G10H1/0066 , G10H1/0553 , G10H2220/341 , G10H2220/401 , G10H2220/415
摘要： Method and apparatus entraining interactive media players into a sustained experience of "Kinesthetic Spatial Sync" defined as a perceived simultaneity and spatial superposition between a non-tactile, full body input contro process and immersive multisensory feedback. Asynchronous player input actions and clock-synchronous media feedback events exhibit a seamless synesthesia or multisensory events fused into an integral event perception, this being between musical sound (hearing), visual responses (sight), and body kinesthetic (radial extension, angular position, height, speed, timing and precision). This non-tactile interface process and multisensory feedback
摘要翻译：将交互式媒体播放器带入“动感空间同步”的持续体验中的方法和设备被定义为非触觉，全身输入控制过程和沉浸式多感觉反馈之间的感知同时性和空间叠加。异步播放器输入动作和时钟同步媒体反馈事件呈现融合到整体事件感知中的无缝感觉或多感觉事件，这是在音乐声音（听觉），视觉响应（视觉）和身体动觉（径向延伸，角位置，高度，速度，时间和精度）。这种非触觉界面过程和多感觉反馈

4. 发明申请

WO2007031782A1 DEVICE FOR INDICATING DIRECTION TO PREDETERMINED LOCATION 审中-公开
标题翻译：用于指示预定位置的设备
公开(公告)号：WO2007031782A1
公开(公告)日：2007-03-22
申请号：PCT/GB2006/003452
申请日：2006-09-18
申请人： CRACOL DEVELOPMENTS LTD , CLARK, David , BLANCHARD, Claude, Georges, Andre
发明人： CLARK, David , BLANCHARD, Claude, Georges, Andre
IPC分类号： G01C17/00
CPC分类号： G01C17/28 , G01C21/20 , G01S19/48
摘要： A non-navigation device for assisting the orientation of a user towards a predetermined location, comprising, operatively connected together; a GPS receiver; a compass; a memory device; and a first indicator for informing the user of the orientation of the non- navigation device, wherein the GPS receiver provides current location data concerning the location of the non-navigation device when located in a first location so as to receive GPS signals, and the memory device stores the current location data, such that on movement of the non-navigation device to a second location shielded from GPS signals, orientation data concerning the orientation of the non-navigation device in the second location is determined by the compass in conjunction with the current location data stored in the memory device, while the non-navigation device is shielded from GPS signals.
摘要翻译：一种用于辅助用户朝向预定位置的定向的非导航设备，包括：可操作地连接在一起; GPS接收机; 指南针记忆装置; 以及用于向用户通知非导航装置的方向的第一指示符，其中，当位于第一位置时，GPS接收器提供关于非导航装置的位置的当前位置数据，以便接收GPS信号，并且存储器装置存储当前位置数据，使得在非导航装置移动到与GPS信号屏蔽的第二位置时，关于第二位置中的非导航装置的取向的取向数据由指南针结合存储在存储设备中的当前位置数据，而非导航设备被屏蔽掉GPS信号。

5. 发明申请

WO2005072433A2 TOXIN INDUCED SYMPATHECTOMY 审中-公开
标题翻译：毒素诱导的症状
公开(公告)号：WO2005072433A2
公开(公告)日：2005-08-11
申请号：PCT/US2005/003081
申请日：2005-01-26
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , CARROLL, Ian , CLARK, David , MACKEY, Sean
发明人： CARROLL, Ian , CLARK, David , MACKEY, Sean
IPC分类号： F16C17/10 , F16C33/10 , F16C33/20 , F16C33/74 , H02K5/16 , H02K7/08
CPC分类号： A61K38/4893
摘要： A selective and extended sympathetic nerve block is achieved by administration of a botulinum toxin at and/or around a targeted sympathetic ganglion. The toxin induced sympathetic block finds use for the treatment of sympathetically maintained pain. The toxin induced sympathetic block is also used to treat cardiovascular conditions of sympathetically maintained vasoconstriction; and of undesirable smooth muscle spasm.
摘要翻译：通过在目标交感神经节和/或周围施用肉毒杆菌毒素来实现选择性和延长的交感神经阻滞。毒素诱导的交感神经阻滞可用于治疗交感神经保持的疼痛。毒素诱导的交感神经阻滞也用于治疗交感神经维持血管收缩的心血管疾病; 和不希望的平滑肌痉挛。

6. 发明申请

WO2014113666A1 DEVICES, SYSTEMS, AND METHODS FOR ACTIVE VIBRATION CONTROL FORCE, SPEED AND VIBRATION MONITORING AND CONTROL 审中-公开
标题翻译：主动振动控制力，速度和振动监测与控制的装置，系统和方法
公开(公告)号：WO2014113666A1
公开(公告)日：2014-07-24
申请号：PCT/US2014/012044
申请日：2014-01-17
申请人： LORD CORPORATION , SWANSON, Doug A. , BLACK, Paul R. , CLARK, David , FERGUSON, Matthew K. , RYU, Jihan
发明人： SWANSON, Doug A. , BLACK, Paul R. , CLARK, David , FERGUSON, Matthew K. , RYU, Jihan
IPC分类号： B64C27/00 , F16F15/22 , G01H1/00
CPC分类号： G05D19/02 , B64C27/001 , G01H1/00 , G05B15/02 , G10K2210/1291
摘要： The present subject matter relates to systems and methods for active vibration control system speed monitoring and control in which a speed protection monitor configured to receive index pulses as inputs to monitor the speed of one or more force generators. A rotary actuator control system can be connected in communication with the speed protection monitor and the one or more force generators, wherein the rotary actuator control system is configured to shut down or adjust the speed of the one or more force generators if the one or more force generators are determined to be operating at undesired speeds.
摘要翻译：本主题涉及用于主动振动控制系统速度监测和控制的系统和方法，其中速度保护监视器被配置为接收索引脉冲作为输入以监视一个或多个力发生器的速度。旋转致动器控制系统可以与速度保护监视器和一个或多个力发生器连接，其中旋转致动器控制系统被配置为关闭或调整一个或多个力发生器的速度，如果一个或多个力发生器被确定为以不期望的速度运行。

7. 发明申请

WO2014075030A1 ACTIVE VIBRATION CONTROL SYSTEMS AND METHODS FOR VEHICLES 审中-公开
标题翻译：主动振动控制系统和车辆方法
公开(公告)号：WO2014075030A1
公开(公告)日：2014-05-15
申请号：PCT/US2013/069524
申请日：2013-11-12
申请人： LORD CORPORATION , SWANSON, Doug A. , EDEAL, David W. , PEDERSEN, Douglas G. , CLARK, David
发明人： SWANSON, Doug A. , EDEAL, David W. , PEDERSEN, Douglas G. , CLARK, David
IPC分类号： B64C27/00 , F16F15/00
CPC分类号： B64C27/001 , B64C2027/004 , F16F15/002 , G05D19/02
摘要： Active vibration control systems (100) and methods are provided herein. Systems (100) are expandable and include a plurality of vibration control devices (110) and at least a first controller (102) digitally linked with a second controller (104) via an interface (108). The first and the second controllers exchange information for generation of a force control command (FCC) either the first or second controller. The FCC is then executed at a first vibration control device (110) of the plurality of vibration control devices (FG) for providing active vibration control within a vehicle. A method of providing vibration control in a vehicle includes providing a plurality of active vibration control devices (100) and providing at least a first controller (102) digitally linked with a second controller (104). The method further includes generating a FCC using information exchanged between the first and the second controllers. The method further includes sending the FCC to a first vibration control device (110) of the plurality of devices (FG).
摘要翻译：本文提供了主动振动控制系统（100）和方法。系统（100）是可扩展的并且包括多个振动控制装置（110）和至少第一控制器（102），其经由接口（108）与第二控制器（104）数字联接。第一和第二控制器交换用于产生第一或第二控制器的力控制命令（FCC）的信息。然后，在多个振动控制装置（FG）的第一振动控制装置（110）处执行FCC，以在车辆内提供主动振动控制。一种在车辆中提供振动控制的方法包括提供多个主动振动控制装置（100）并且提供至少与第二控制器（104）数字连接的第一控制器（102）。该方法还包括使用在第一和第二控制器之间交换的信息来生成FCC。该方法还包括将FCC发送到多个设备（FG）的第一振动控制设备（110）。

8. 发明申请

WO2012012642A1 TRICYCLIC COMPOUNDS AND METHDS OF MAKING AND USING SAME 审中-公开
标题翻译：三元化合物及其制备和使用方法
公开(公告)号：WO2012012642A1
公开(公告)日：2012-01-26
申请号：PCT/US2011/044864
申请日：2011-07-21
申请人： ZAFGEN CORPORATION , CLARK, David , CRAMP, Susan, Mary , DYKE, Hazel, Joan , PALLIN, Thomas, David , ZAHLER, Robert
发明人： CLARK, David , CRAMP, Susan, Mary , DYKE, Hazel, Joan , PALLIN, Thomas, David , ZAHLER, Robert
IPC分类号： C07D491/00 , C07D493/00 , C07D513/00 , A61K31/353 , A61K31/425 , A61K31/4738 , A61P3/04
CPC分类号： A61K31/35 , A61K9/0053 , A61K31/335 , A61K31/397 , A61K31/4025 , A61K31/429 , A61K31/4741 , A61K31/5377 , C07D491/048 , C07D493/04 , C07D513/04
摘要： The invention provides tricyclic compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tricyclic compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
摘要翻译：本发明提供三环化合物及其在治疗医学疾病如肥胖症中的用途。提供制备各种三环化合物的药物组合物和方法。化合物被认为具有抗甲硫氨酰氨基肽酶2的活性。

9. 发明申请

WO2010065930A1 METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING NARCOTIC WITHDRAWAL SYMPTOMS 审中-公开
标题翻译：治疗或预防麻醉性抽搐症状的方法和组合
公开(公告)号：WO2010065930A1
公开(公告)日：2010-06-10
申请号：PCT/US2009/066877
申请日：2009-12-04
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , PELTZ, Gary , CLARK, David , CHU, Lawrence
发明人： PELTZ, Gary , CLARK, David , CHU, Lawrence
IPC分类号： C07K14/435 , C12N15/85
CPC分类号： A61K31/4178 , A61K31/444 , A61K31/485 , A61K31/495 , A61K2300/00
摘要： This invention provides methods and pharmaceutical compositions for preventing or treating physical dependence and/or withdrawal associated with narcotic use, in particular by modulating a 5-HT3 receptor. Using a computational genetic approach in mice, a gene conserved between mice and humans was identified as candidate as a modulator of physical dependence to morphine. Administration of compounds that modulate 5-HT3 receptors was found to control withdrawal from morphine in mice and humans.
摘要翻译：本发明提供了用于预防或治疗与麻醉药物使用相关的身体依赖和/或戒断的方法和药物组合物，特别是通过调节5-HT 3受体。在小鼠中使用计算遗传学方法，将小鼠和人之间保守的基因鉴定为作为吗啡物理依赖的调节剂的候选物。发现调节5-HT 3受体的化合物的给药可以控制小鼠和人类的吗啡戒断。

10. 发明申请

WO2012112909A1 ENDODONTIC BURS, KITS, AND METHODS FOR USING ENDODONTIC BURS 审中-公开
标题翻译： ENDODONTIC BURS，KITTS和方法使用ENDODONTIC BURS
公开(公告)号：WO2012112909A1
公开(公告)日：2012-08-23
申请号：PCT/US2012/025675
申请日：2012-02-17
申请人： SS WHITE BURS, INC. , CLARK, David , QUIGLEY, Michael , MILES, Brant
发明人： CLARK, David , QUIGLEY, Michael , MILES, Brant
IPC分类号： A61C3/02
CPC分类号： A61C5/42
摘要： A conical dental bur for endodontic procedures, including exploration, deep troughing, enlargement of orifices, and canal navigation is presented. The bur of the present invention has a narrow, conical bur head with cutting members along its length. The head of the bur of the present invention is mounted to a shank that tapers to the bur head, allowing microscopic observations of endodontic procedures. The bur may be manufactured of tungsten carbide, diamond, ceramics, or other materials. Burs according to the present invention of various shapes and sizes, suited for particular procedures, may be packaged together in kits. Methods of using the burs in endodontic procedures are also disclosed.
摘要翻译：提供牙髓手术的锥形牙科钻头，包括探查，深槽，孔口扩大和运河导航。本发明的钻头具有窄的圆锥形头部，其切割构件沿着其长度。本发明的头部的头部被安装到一个向头部头部变细的柄部，允许对根管手术的显微观察。钻头可以由碳化钨，金刚石，陶瓷或其他材料制成。根据本发明的适用于特定程序的各种形状和尺寸的袋可以一起包装在套件中。还公开了在根管手术中使用毛刺的方法。

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