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1. 发明申请

WO2003039437A2 ORAL VERABREICHBARE PHARMAZEUTISCHE ZUBEREITUNG UMFASSEND LIPOSO MAL VERKAPSELTES TAXOL 审中-公开
标题翻译：口服给药的药物制剂，综合LIPOSO MAL包封紫杉醇
公开(公告)号：WO2003039437A2
公开(公告)日：2003-05-15
申请号：PCT/DE2002/004120
申请日：2002-11-06
申请人： MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN , RESZKA, Regina , FICHTNER, Iduna
发明人： RESZKA, Regina , FICHTNER, Iduna
IPC分类号： A61K
CPC分类号： A61K38/19 , A61K9/127 , A61K9/1271 , A61K31/337 , A61K38/13 , A61K2300/00
摘要： Die Erfindung betrifft pharmazeutische Zubereitungen, die zur oralen Anwendung von liposomal verkapseltem Taxol, seinen Derivaten und Taxan geeignet sind. Bevorzugt enthalten sie zusätzlich mindestens einen Immunmodulator, vorzugsweise Cyclosporine, und/oder mindestens ein Cytokin, vorzugsweise PEG-Cytokine.
摘要翻译：本发明涉及药物制剂，其适合于脂质体包囊的泰素，其衍生物和紫杉烷的口服应用。优选地，它们还含有至少一种免疫调节剂，优选环孢菌素，和/或至少一种细胞因子，优选PEG-细胞因子。

2. 发明申请

WO2003039437A3 ORAL VERABREICHBARE PHARMAZEUTISCHE ZUBEREITUNG UMFASSEND LIPOSO MAL VERKAPSELTES TAXOL 审中-公开
公开(公告)号：WO2003039437A3
公开(公告)日：2003-05-15
申请号：PCT/DE2002/004120
申请日：2002-11-06
申请人： MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN , RESZKA, Regina , FICHTNER, Iduna
发明人： RESZKA, Regina , FICHTNER, Iduna
IPC分类号： A61K9/127
摘要： Die Erfindung betrifft pharmazeutische Zubereitungen, die zur oralen Anwendung von liposomal verkapseltem Taxol, seinen Derivaten und Taxan geeignet sind. Bevorzugt enthalten sie zusätzlich mindestens einen Immunmodulator, vorzugsweise Cyclosporine, und/oder mindestens ein Cytokin, vorzugsweise PEG-Cytokine.

3. 发明申请

WO2013079594A1 DEVICE AND METHODS TO DIAGNOSE PANCREATIC CANCER 审中-公开
标题翻译：诊断胰腺癌的装置和方法
公开(公告)号：WO2013079594A1
公开(公告)日：2013-06-06
申请号：PCT/EP2012/073965
申请日：2012-11-29
申请人： METANOMICS HEALTH GMBH , UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN , ERNST-MORITZ-ARNDT UNIVERSITÄT GREIFSWALD , RESZKA, Regina , KAMLAGE, Beate , KALTHOFF, Holger , SCHNIEWIND, Bodo , MAYERLE, Julia , LERCH, Markus M. , PILARSKY, Christian , GRÜTZMANN, Robert
发明人： RESZKA, Regina , KAMLAGE, Beate , KALTHOFF, Holger , SCHNIEWIND, Bodo , MAYERLE, Julia , LERCH, Markus M. , PILARSKY, Christian , GRÜTZMANN, Robert
IPC分类号： G01N33/574
CPC分类号： G01N33/57438 , G01N2033/57461
摘要： The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreatic cancer in a subject, a method for identifying whether a subject is in need for a therapy of pancreatic cancer or a method for determining whether a pancreatic cancer therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
摘要翻译：本发明涉及诊断方法领域。具体地，本发明考虑了用于诊断受试者中胰腺癌的方法，用于鉴定受试者是否需要胰腺癌治疗的方法或者确定胰腺癌治疗是否成功的方法。本发明还涉及用于执行上述方法的工具，例如诊断装置。

4. 发明申请

WO2003077930A1 VERWENDUNG VON MINDESTENS EINEM FLAVONOID DES QUERCETINS ZUR ERHÖHUNG DES SPIEGELS VON NÜTZLICHEN KURZKETTIGEN FETTSÄUREN IM UNTEREN INTESTINALTRAKT 审中-公开
标题翻译： USE一种类黄酮槲皮素至少对增强有用镜短链脂肪酸下部肠道
公开(公告)号：WO2003077930A1
公开(公告)日：2003-09-25
申请号：PCT/DE2003/000475
申请日：2003-02-15
申请人： G.O.T. THERAPEUTICS GMBH , SCHMIEDL, Detlef , RESZKA, Regina
发明人： SCHMIEDL, Detlef , RESZKA, Regina
IPC分类号： A61K31/70
CPC分类号： A61K45/06 , A61K31/352 , A61K31/702 , A61K31/7048 , A61K31/716 , A61K31/718 , A61K2300/00
摘要： Die Erfindung betrifft die Verwendung von mindestens einem Flavonoid des Quercetins in Kombination mit mindestens einem Saccharid ausgewählt aus resistenter Stärke (RS), einem Nichtstärke-Polysaccharid oder einem Oligosaccharid zur kontinuierlich verbesserten Erhöhung des Spiegels von nützlichen kurzkettigen Fettsäuren (SCFA) im unteren Intestinaltrakt sowie zur Stimulierung der Rückresorption von Flüssigkeit und gelöster Elektrolyte.
摘要翻译：本发明涉及一种组合使用至少一种类黄酮槲皮素与至少一种糖从抗性淀粉（RS）中选择，非淀粉的多糖或寡糖，不断改进的有用的短链脂肪酸在肠道下部的水平（SCFA）的仰角以及刺激的流体和电解质重吸收溶解。

5. 发明申请

WO2012164026A8 METHODS FOR DIAGNOSING MULTIPLE SCLEROSIS 审中-公开
公开(公告)号：WO2012164026A8
公开(公告)日：2012-12-06
申请号：PCT/EP2012/060262
申请日：2012-05-31
申请人： METANOMICS HEALTH GMBH , RESZKA, Regina , RENNEFAHRT, Ulrike , CARVALHO, Susan , HEMMER, Bernhard
发明人： RESZKA, Regina , RENNEFAHRT, Ulrike , CARVALHO, Susan , HEMMER, Bernhard
IPC分类号： G01N33/564
摘要： The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing multiple sclerosis in a subject, a method for identifying whether a subject is in need for a therapy of multiple sclerosis or a method for determining whether a multiple sclerosis therapy is successful. Moreover, contributed is a method for diagnosing or predicting the risk of an active status of multiple sclerosis in a subject. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.

6. 发明申请

WO2013014286A2 MEANS AND METHODS FOR DIAGNOSING AND MONITORING HEART FAILURE IN A SUBJECT 审中-公开
标题翻译：诊断和监测受试者心力衰竭的手段和方法
公开(公告)号：WO2013014286A2
公开(公告)日：2013-01-31
申请号：PCT/EP2012/064823
申请日：2012-07-27
申请人： METANOMICS GMBH , RUPRECHT-KARLS-UNIVERISTÄT HEIDELBERG , RESZKA, Regina , FUHRMANN, Jens , KASTLER, Jürgen , BETHAN, Bianca , KLUTTIG, Martin , KATUS, Hugo , FREY, Norbert , WOLF, Johanna , WEIS, Tanja
发明人： RESZKA, Regina , FUHRMANN, Jens , KASTLER, Jürgen , BETHAN, Bianca , KLUTTIG, Martin , KATUS, Hugo , FREY, Norbert , WOLF, Johanna , WEIS, Tanja
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N30/72 , G01N30/8668 , G01N33/50 , G01N33/62 , G01N33/6806 , G01N33/743 , G01N33/92 , G01N2030/3076 , G01N2030/8813 , G01N2405/04 , G01N2405/08 , G01N2560/00 , G01N2800/325 , G01N2800/56 , Y10T436/143333 , Y10T436/144444 , Y10T436/145555 , Y10T436/146666 , Y10T436/147777 , Y10T436/148888 , Y10T436/163333 , Y10T436/171538 , Y10T436/173845 , Y10T436/200833 , Y10T436/201666 , Y10T436/203332 , Y10T436/21
摘要： The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject and a method for monitoring progression or regression of heart failure in a subject. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
摘要翻译：本发明涉及诊断方法领域。具体而言，本发明考虑了用于诊断受试者中的心力衰竭的方法以及用于监测受试者中心力衰竭的进展或衰退的方法。本发明还涉及用于执行上述方法的工具，例如诊断设备。

7. 发明申请

WO2011092285A2 MEANS AND METHODS FOR DIAGNOSING HEART FAILURE IN A SUBJECT 审中-公开
标题翻译：用于诊断主体心脏衰竭的手段和方法
公开(公告)号：WO2011092285A2
公开(公告)日：2011-08-04
申请号：PCT/EP2011/051208
申请日：2011-01-28
申请人： METANOMICS GMBH , RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG , FUHRMANN, Jens , RESZKA, Regina , KASTLER, Jürgen , BUSCH, Kristina , LEIBOLD, Edgar , KATUS, Hugo , FREY, Norbert , WOLF, Johanna , WEIS, Tanja
发明人： FUHRMANN, Jens , RESZKA, Regina , KASTLER, Jürgen , BUSCH, Kristina , LEIBOLD, Edgar , KATUS, Hugo , FREY, Norbert , WOLF, Johanna , WEIS, Tanja
IPC分类号： G01N33/92
CPC分类号： G01N33/92 , G01N33/64 , G01N33/6893 , G01N2570/00 , G01N2800/325 , G01N2800/52
摘要： The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing heart failure in a subject, a method for identifying whether a subject is in need for a therapy of heart failure or a method for determining whether a heart failure therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
摘要翻译：本发明涉及诊断方法领域。具体地，本发明考虑了用于诊断受试者的心力衰竭的方法，用于识别受试者是否需要心力衰竭治疗的方法或用于确定心力衰竭疗法是否成功的方法。本发明还涉及用于执行上述方法的工具，例如诊断装置。

8. 发明申请

WO2011067243A1 MEANS AND METHODS FOR DIAGNOSING MULTIPLE SCLEROSIS 审中-公开
标题翻译：用于诊断多发性硬化的手段和方法
公开(公告)号：WO2011067243A1
公开(公告)日：2011-06-09
申请号：PCT/EP2010/068508
申请日：2010-11-30
申请人： METANOMICS HEALTH GMBH , CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN , RESZKA, Regina , RENNEFAHRT, Ulrike , HEWELT, Andreas , KASTLER, Jürgen , FUHRMANN, Jens , ZIPP, Frauke , INFANTE-DUARTE, Carmen
发明人： RESZKA, Regina , RENNEFAHRT, Ulrike , HEWELT, Andreas , KASTLER, Jürgen , FUHRMANN, Jens , ZIPP, Frauke , INFANTE-DUARTE, Carmen
IPC分类号： G01N33/564
CPC分类号： G01N33/564 , G01N2800/285 , G01N2800/50 , G01N2800/52
摘要： The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing multiple sclerosis in a subject, a method for identifying whether a subject is in need for a therapy of multiple sclerosis or a method for determining whether a multiple sclerosis therapy is successful. Moreover, contributed is a method for diagnosing or predicting the risk of an active status of multiple sclerosis in a subject. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
摘要翻译：本发明涉及诊断方法领域。具体地，本发明考虑了用于诊断受试者中的多发性硬化的方法，用于鉴定受试者是否需要多发性硬化症的治疗的方法或用于确定多发性硬化症疗法是否成功的方法。此外，贡献是用于诊断或预测受试者中多发性硬化的活动状态的风险的方法。本发明还涉及用于执行上述方法的工具，例如诊断装置。

9. 发明申请

WO2011151252A2 MEANS AND METHODS FOR DIAGNOSING PANCREATIC CANCER IN A SUBJECT 审中-公开
标题翻译：用于诊断主体中胰腺癌的手段和方法
公开(公告)号：WO2011151252A2
公开(公告)日：2011-12-08
申请号：PCT/EP2011/058670
申请日：2011-05-26
申请人： METANOMICS HEALTH GMBH , UNIKLINIKUM SCHLESWIG-HOLSTEIN , ERNST-MORITZ-ARNDT UNIVERSITÄT , KAMLAGE, Beate , RESZKA, Regina , KLUTTIG, Martin , KALTHOFF, Holger , SCHNIEWIND, Bodo , MEYERLE, Julia , LERCH, Markus
发明人： KAMLAGE, Beate , RESZKA, Regina , KLUTTIG, Martin , KALTHOFF, Holger , SCHNIEWIND, Bodo , MEYERLE, Julia , LERCH, Markus
IPC分类号： G01N33/574
CPC分类号： G01N33/574 , G01N33/57438
摘要： The present invention relates to the field of diagnostic methods. Specifically, the present invention contemplates a method for diagnosing pancreatic cancer in a subject, a method for identifying whether a subject is in need for a therapy of pancreatic cancer or a method for determining whether a pancreatic cancer therapy is successful. The invention also relates to tools for carrying out the aforementioned methods, such as diagnostic devices.
摘要翻译：本发明涉及诊断方法领域。具体地，本发明考虑了用于诊断受试者中胰腺癌的方法，用于鉴定受试者是否需要胰腺癌治疗的方法或者确定胰腺癌治疗是否成功的方法。本发明还涉及用于执行上述方法的工具，例如诊断装置。

10. 发明申请

WO2010139711A1 MEANS AND METHODS FOR DIAGNOSING PROSTATE CARCINOMAS 审中-公开
标题翻译：用于诊断前列腺癌的手段和方法
公开(公告)号：WO2010139711A1
公开(公告)日：2010-12-09
申请号：PCT/EP2010/057680
申请日：2010-06-02
申请人： METANOMICS HEALTH GMBH , CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN , KAMLAGE, Beate , BETHAN, Bianca , RESZKA, Regina , LEIBOLD, Edgar , JUNG, Klaus , LEIN, Michael , KRISTIANSEN, Glen
发明人： KAMLAGE, Beate , BETHAN, Bianca , RESZKA, Regina , LEIBOLD, Edgar , JUNG, Klaus , LEIN, Michael , KRISTIANSEN, Glen
IPC分类号： G01N33/574
CPC分类号： G01N33/57484 , G01N33/57434
摘要： The present invention relates to a method, preferably an ex vivo method, for diagnosing prostate carcinomas and/or predisposition thereof comprising determining at least one metabolite in a test sample of a subject suspected to suffer from prostate carcinomas or to have a predisposition therefor and comparing said at least one metabolite to a reference, whereby prostate carcinomas or a predisposition therefor is to be diagnosed. Moreover, the present invention encompasses a collection of metabolites, a data collection comprising characteristic values of metabolites and a storage medium comprising said data collection. Furthermore, the present invention also relates to a system comprising means for comparing characteristic values of metabolites of a sample operatively linked to a data storage medium. Further encompassed by the present invention are diagnostic means comprising at least one metaboiite and the use of said at least one metabolite for the manufacture of diagnostic means for or for diagnosing prostate carcinomas. Finally, the present invention pertains to a method for identifying prostate carcinoma-related metabolites.
摘要翻译：本发明涉及用于诊断前列腺癌和/或其倾向性的方法，优选离体方法，其包括测定怀疑患有前列腺癌的受试者的测试样品中的至少一种代谢物或具有易感性并比较将至少一种代谢物称为参考，由此前列腺癌或其易感性被诊断。此外，本发明包括代谢物的集合，包括代谢物的特征值的数据收集和包含所述数据收集的存储介质。此外，本发明还涉及一种系统，其包括用于比较可操作地连接到数据存储介质的样品的代谢物的特征值的装置。本发明进一步包括的是诊断方法，其包括至少一种生物元素和所述至少一种代谢产物用于制造用于诊断前列腺癌或用于诊断前列腺癌的诊断方法。最后，本发明涉及鉴定前列腺癌相关代谢物的方法。

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