专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2006089118A3 PHOTOREACTIVE SYSTEM AND METHODS FOR PROPHYLACTIC TREATMENT OF ATHEROSCLEROSIS 审中-公开
标题翻译：光学治疗系统和方法治疗甲状腺功能亢进
公开(公告)号：WO2006089118A3
公开(公告)日：2007-11-15
申请号：PCT/US2006005648
申请日：2006-02-17
申请人： LIGHT SCIENCES ONCOLOGY INC , CHEN JAMES C , YEO NICHOLAS , BURWELL PHILLIP , WENGER THOMAS
发明人： CHEN JAMES C , YEO NICHOLAS , BURWELL PHILLIP , WENGER THOMAS
IPC分类号： A61M29/00
CPC分类号： A61K41/0071 , A61N5/0601 , A61N5/062 , A61N2005/0602 , A61N2005/0651 , A61N2005/0661
摘要： The present invention provides a prophylactic light activated treatment method for subjects at risk of a plaque-mediated thrombotic event, such as acute coronary syndromes. In one embodiment, the subject receives a dose of photosensitizer sufficient to result in a concentration of photosensitizer in the neovascularization associated with atherosclerotic disease to permit effective photodynamic therapy. Light of a wavelength that excites the photosensitizer, but that does not to any significant extent penetrate to an adventitial layer of the blood vessel, is applied to the region of the blood vessel. The therapeutic light dose, which may be applied in sequential stages, is sufficient to cause closure of neovasculature leakage and lead to plaque stabilization and reduced adverse clinical outcomes. The present invention further provides light transmission devices and systems useful in carrying out the methods of the present invention.
摘要翻译：本发明为患有斑块介导的血栓形成事件风险的受试者，例如急性冠状动脉综合征提供预防性光活化治疗方法。在一个实施方案中，受试者接受足以导致与动脉粥样硬化疾病相关的新血管形成中的光敏剂浓度以允许有效的光动力疗法的剂量的光敏剂。激发光敏剂的波长的光被施加到血管的区域，而不是任何显着程度的透射到血管的外膜层。可以按顺序施用的治疗光剂量足以引起新血管渗漏的闭合并导致斑块稳定化并减少不良临床结果。本发明还提供了用于实施本发明的方法的光传输装置和系统。

2. 发明申请

WO2008086376A3 THERAPEUTIC DEVICES FOR THE TREATMENT OF VARICOSITY 审中-公开
标题翻译：用于治疗病变的治疗设备
公开(公告)号：WO2008086376A3
公开(公告)日：2008-10-09
申请号：PCT/US2008050545
申请日：2008-01-08
申请人： LIGHT SCIENCES ONCOLOGY INC , GUO ZIHONG , YEO NICHOLAS , BURWELL PHIL , CESPEDES IGNACIO , WATTERS WADE
发明人： GUO ZIHONG , YEO NICHOLAS , BURWELL PHIL , CESPEDES IGNACIO , WATTERS WADE
IPC分类号： A61N5/06
CPC分类号： A61B18/24 , A61N5/0601 , A61N5/062 , A61N2005/0652 , A61N2005/0659 , A61N2005/0662
摘要： The present invention provides methods and devices for treating varicosities, including varicose veins, by administering therapeutic energy. In one embodiment, energy is delivered to the interior of a vessel using a catheter containing an energy emitting source, thereby causing ablation of the vessel without damage to surrounding tissue. The methods of the invention may further include the use of a photosensitizer that binds to the interior of the vessel wall or a chromophore, both of which generate localized thermal damage to the interior vessel wall without harming surrounding tissue. In another embodiment, the present invention provides less invasive methods of treating varicosities, which include introducing a heat-activated glue, photosensitizer solution, or heatable liquid into a vessel being treated and administering light from an external source sufficient to activate the glue to close the vessel, activate the photosensitizer to damage the vessel, or heat the liquid to damage the vessel.
摘要翻译：本发明提供了通过施用治疗能量来治疗静脉曲张的方法和装置，包括静脉曲张。在一个实施例中，使用包含能量发射源的导管将能量输送到容器的内部，由此引起容器的消融而不损坏周围的组织。本发明的方法还可以包括使用光敏剂，其结合血管壁或发色团的内部，两者都会对内部血管壁产生局部热损伤而不伤害周围组织。在另一个实施方案中，本发明提供了治疗静脉曲张的侵入性较差的方法，其包括将热活化胶，光敏剂溶液或可加热液体引入正在治疗的血管中，并从外部来源施加足以激活胶水的光以封闭容器，激活光敏剂以损坏容器，或加热液体以损坏容器。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式