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1. 发明申请

WO2011132153A2 METHODS AND DEVICES FOR APPLYING TISSUE SEALANTS AND ADHESIVES 审中-公开
标题翻译：用于组织组织密封剂和粘合剂的方法和装置
公开(公告)号：WO2011132153A2
公开(公告)日：2011-10-27
申请号：PCT/IB2011/051714
申请日：2011-04-20
申请人： LIFEBOND LTD. , PREISS-BLOOM, Orahn , ATTAR, Ishay , SHEZIFI, Omer , SHEZIFI, Yuval , SALMAN, Golan
发明人： PREISS-BLOOM, Orahn , ATTAR, Ishay , SHEZIFI, Omer , SHEZIFI, Yuval , SALMAN, Golan
IPC分类号： A61B17/00
CPC分类号： A61B17/00491 , A61B17/07292 , A61B17/1155 , A61B2017/00495 , A61B2017/00858
摘要： Methods of application and devices thereof for tissue adhesives. The adhesives comprise a plurality of components which are provided separately but which are mixed together to form the adhesive. At least one component is a crosslinkable protein solution and at least one other component is a crosslinking material solution. The devices preferably include a mixing unit, which may include dynamic mixing elements, static mixing elements, or a combination of the two.
摘要翻译：用于组织粘合剂的应用方法及其装置。粘合剂包括分开设置但被混合在一起以形成粘合剂的多个组分。至少一种组分是可交联的蛋白质溶液，并且至少一种其它组分是交联材料溶液。装置优选地包括混合单元，其可以包括动态混合元件，静态混合元件或两者的组合。

2. 发明申请

WO2012085916A2 DEVICE AND METHOD FOR DEFLECTING EMBOLI IN AN AORTA 审中-公开
标题翻译：用于在AORTA中定位EMBOLI的装置和方法
公开(公告)号：WO2012085916A2
公开(公告)日：2012-06-28
申请号：PCT/IL2011/000963
申请日：2011-12-22
申请人： SMT RESEARCH AND DEVELOPMENT LTD. , SHEZIFI, Yuval , SHIMON, Dov V. , SALMAN, Iddo , MIKOVSKY, Tzeela
发明人： SHEZIFI, Yuval , SHIMON, Dov V. , SALMAN, Iddo , MIKOVSKY, Tzeela
CPC分类号： A61F2/01 , A61F2002/016 , A61F2002/018 , A61F2220/0008 , A61F2230/0019 , A61F2230/0095
摘要： An intra-vascular device may include a skeleton to hold a blood filter, an upper member to fit into a branch artery of an aorta, and a pair of lower members whose distal ends are not connected to each other, such lower members to press against a wall of an ascending artery and to provide lift to the device so that a middle portion of the device is above a lateral plane of the device. The device may be positioned in a middle area of an aortic arch near but not covering an opening of the branch arteries of the aorta, and may filter or deflect emboli or other large objects from entering into the branch arteries.
摘要翻译：血管内装置可以包括用于保持血液过滤器的骨架，上部构件以配合到主动脉的分支动脉中，以及一对下部构件，其远端彼此不连接，这样的下部构件被压靠上升的动脉的壁并且向装置提供升力，使得装置的中间部分在装置的横向平面之上。该装置可以位于主动脉弓的中间区域中，但是不覆盖主动脉的分支动脉的开口，并且可以过滤或偏转栓塞或其他大物体进入分支动脉。

3. 发明申请

WO2009004625A3 BONE ANCHORING SYSTEM 审中-公开
公开(公告)号：WO2009004625A3
公开(公告)日：2009-01-08
申请号：PCT/IL2008/000913
申请日：2008-07-02
申请人： SCORPION SURGICAL TECHNOLOGIES LTD. , BEN-ARYE, Asaf , SHEZIFI, Yuval , EPSTEIN, Arnon
发明人： BEN-ARYE, Asaf , SHEZIFI, Yuval , EPSTEIN, Arnon
IPC分类号： A61F5/00
摘要： Methods and apparatus for connecting to a bone, which avoid the use of bone screws. A triangular shaped modular implant is used, with two sides of the structure and their respective vertex secured generally within the bone, with the base of the triangle outside the bone. These two arms, whether straight or arcuate, are cannulated, and are held together at their distal ends by a tightened cable that runs through both of the arms. The proximal ends of these arms are connected to a base side that completes the triangular structure. The device may be inserted into a vertebra and the base used for vertebral fusion. Alternatively, the arms themselves may be used to stabilize and fixate adjacent vertebrae, by insertion through adjacent vertebrae trans-segmentally. In the latter case, the vertex may be within the intervertebral space or within the vertebral body close to the intervertebral space.

4. 发明申请

WO2003059180A3 MINIMALLY INVASIVE MODULAR SUPPORT IMPLANT DEVICE AND METHOD 审中-公开
公开(公告)号：WO2003059180A3
公开(公告)日：2003-07-24
申请号：PCT/IL2002/000916
申请日：2002-11-17
申请人： EXPANDIS LTD. , GRUNBERG, Ilan , OHANA, Nissim , BEN-ARYE, Asaf , SHEZIFI, Yuval
发明人： GRUNBERG, Ilan , OHANA, Nissim , BEN-ARYE, Asaf , SHEZIFI, Yuval
IPC分类号： A61B17/58
摘要： Device and method comprising a plate (50) for use in conjunction with at least another one of a plurality of other plates in a modular reconstructing and supporting assembly for reconstructing and supporting a diseased or fractured bone or within a space previously occupied by a diseased intervertebral disc (17) of a patient. The plate is sized small enough to be suitable for separate insertion into the bone or the space, preferably through a canula (44), and stacked on top of each other to construct a scaffolding. The plate has at least two substantially opposite aspects with interlocking features designed to facilitate interlocking of adjacent plates.

5. 发明申请

WO2012160556A1 AN EMBOLIC FILTER DEVICE AND METHOD OF USE THEREOF 审中-公开
标题翻译：一种嵌入式滤波器装置及其使用方法
公开(公告)号：WO2012160556A1
公开(公告)日：2012-11-29
申请号：PCT/IL2012/000208
申请日：2012-05-28
申请人： KEYSTONE HEART LTD. , NAOR, Gil , SHEZIFI, Yuval
发明人： NAOR, Gil , SHEZIFI, Yuval
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2250/0067
摘要： In general, the invention features an intra-vascular device for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels. The device of the invention may include a filter, an central member, additional supporting members, and a delivery cable and may serve to filter or deflect emboli or other large objects from entering protected secondary vessels. The device may be capable of collapse along its longitudinal axis for ease of delivery to the treatment site. The device may further be compatible with common delivery methods used in interventional cardiology (e.g., TAVI procedures). The device may be integrated into the delivery systems. In other embodiments the device may be detachable from the delivery system. Upon deployment, the device may be positioned so as to contact the orifice of one or more secondary blood vessels. Upon retrieval the device may be retracted in an orientation substantially similar to the original deployment orientation.
摘要翻译：通常，本发明的特征在于用于过滤或偏转栓塞或其他大物体进入受保护的次级血管或血管的血管内装置。本发明的装置可以包括过滤器，中心构件，附加的支撑构件和输送电缆，并且可以用于过滤或偏转栓塞或其他大物体进入受保护的次级容器。该装置可能能够沿其纵向轴线折叠以便于输送到治疗部位。该装置还可以与介入心脏病学中使用的常规递送方法（例如，TAVI程序）兼容。该装置可以集成到递送系统中。在其他实施例中，装置可以从输送系统脱离。在展开时，可以将装置定位成接触一个或多个次要血管的孔口。在取回时，可以以基本上类似于原始展开方向的方向缩回装置。

6. 发明申请

WO2004086934A3 MINIMALLY INVASIVE DISTRACTION DEVICE AND METHOD 审中-公开
公开(公告)号：WO2004086934A3
公开(公告)日：2004-10-14
申请号：PCT/IL2004/000171
申请日：2004-02-22
申请人： EXPANDIS LTD. , SHEZIFI, Yuval , GRUNBERG, Ilan , OHANA, Nissim , BEN-ARYE, Asaf
发明人： SHEZIFI, Yuval , GRUNBERG, Ilan , OHANA, Nissim , BEN-ARYE, Asaf
IPC分类号： A61B17/56
摘要： A device (10) for distracting and supporting two substantially opposing tissue surfaces in a patient’s body, to be introduced within the tissue surfaces in a minimally invasive procedure. The device comprises: a wrapping element (12); and an expandable structure (24) insertable between the two substantially opposing suport surfaces of the wrapping element, adapted to be expanded between the two substantially opposing surfaces to a predetermined dimension.

7. 发明申请

WO2003059180A2 MINIMALLY INVASIVE MODULAR SUPPORT IMPLANT DEVICE AND METHOD 审中-公开
标题翻译：最小的入侵模块化支持植入器件和方法
公开(公告)号：WO2003059180A2
公开(公告)日：2003-07-24
申请号：PCT/IL2002/000916
申请日：2002-11-17
申请人： EXPANDIS LTD. , GRUNBERG, Ilan , OHANA, Nissim , BEN-ARYE, Asaf , SHEZIFI, Yuval
发明人： GRUNBERG, Ilan , OHANA, Nissim , BEN-ARYE, Asaf , SHEZIFI, Yuval
IPC分类号： A61B17/58
CPC分类号： A61B17/8852 , A61B17/8858 , A61B90/92 , A61F2/30965 , A61F2/44 , A61F2/4455 , A61F2002/30062 , A61F2002/30225 , A61F2002/30266 , A61F2002/30331 , A61F2002/30383 , A61F2002/30387 , A61F2002/30401 , A61F2002/30599 , A61F2002/30604 , A61F2002/30677 , A61F2002/448 , A61F2210/0004 , A61F2220/0025 , A61F2220/0033 , A61F2230/0069 , A61F2230/0082 , A61F2250/0063 , A61F2310/00017 , A61F2310/00023 , A61F2310/00161 , A61F2310/00179 , A61F2310/00293 , A61F2310/00796 , A61F2310/00976
摘要： Device and method are disclosed of a plate for use in conjunction with at least another one of a plurality of other plates in a modular reconstructing and supporting assembly for reconstructing and supporting a diseased or fractured bone or within a space previously occupied by a diseased intervertebral disc of a patient. The plate is sized small enough to be suitable for separate insertion into the bone or the space, preferably through a canule, and arrangement with the other plates adjacently one on top of the other to construct scaffolding, so as to provide a supporting prosthesis.In another preferred embodiment the plate has at least two substantially opposite aspects with interlocking features designed to facilitate interlocking of adjacent plates so as to prevent or restrain their sliding off each other.
摘要翻译：公开了一种用于与模块化重建和支撑组件中的多个其它板中的至少另一个板结合使用的装置和方法，用于重构和支撑患病或断裂的骨骼，或者在先前由病变椎间盘占据的空间内的病人该板的尺寸足够小以适合于单独插入到骨骼或空间中，优选地通过一个小管，并且与其他板相互排列，一个在另一个之上，以构成脚手架，以便提供支撑假体。另一个优选实施例中，板具有至少两个基本上相反的方面，其中互锁特征被设计成便于相邻板的互锁，以便防止或限制它们彼此滑动。

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