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    • 1. 发明申请
    • METHOD FOR DISCOVERING AN ORTHOLOGOUS GENE USING GENE NOMENCLATURE
    • 使用基因名称发现人类基因的方法
    • WO2011087266A3
    • 2011-12-01
    • PCT/KR2011000209
    • 2011-01-12
    • KOREA BASIC SCIENCE INSTKWON KYUNG-HOONCHOI SUN SHIMPARK SEUNG GU
    • KWON KYUNG-HOONCHOI SUN SHIMPARK SEUNG GU
    • C12Q1/68G01N33/68G06F19/00
    • G06F19/18G06F19/14G06F19/22G06F19/28Y02A90/24Y02A90/26
    • The present invention relates to a method for discovering an orthologous gene, and more specifically, to an orthologous gene identification method, which comprises: classifying two genes according to molecular biological functions and biological processes by using gene ontology; preparing a gene ontology tree to analyze the gene classification pattern; and identifying an orthologous gene if the number of common interconnects is greater than that between ordinary genes yet the sequence is similar. The method of the present invention can be easily used for the analysis of gene function, and using an orthologous gene, the study of gene function of a species whose gene function is relatively easy to analyze can be applied to the analysis of gene function of a species, such as humans, which is difficult to study. Therefore, the method of the present invention is useful for the prevention or treatment of human diseases or the development of new drugs.
    • 本发明涉及一种用于发现直系同源基因的方法,更具体地涉及直系同源基因鉴定方法,其包括:通过使用基因本体,根据分子生物学功能和生物学过程对两个基因进行分类; 准备基因本体树分析基因分类模式; 并且如果共同互连的数量大于普通基因之间,而序列相似,则鉴定直系同源基因。 本发明的方法可以容易地用于基因功能的分析,并且使用直系同源基因,基因功能相对容易分析的物种的基因功能的研究可以应用于基因功能的分析 物种,如人类,难以研究。 因此,本发明的方法可用于预防或治疗人类疾病或开发新药。