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    • 3. 发明申请
    • KNOWLEDGE GRAPH-BASED CLINICAL DIAGNOSIS ASSISTANT
    • 基于知识图的临床诊断助手
    • WO2018077906A1
    • 2018-05-03
    • PCT/EP2017/077208
    • 2017-10-24
    • KONINKLIJKE PHILIPS N.V.
    • DATLA, Vivek, VarmaAL HASAN, Sheikh, SadidFARRI, Oladimeji, FeyisetanLIU, JunyiLEE, Kathy, Mi, YoungQADIR, AshequlPRAKASH, Adi
    • G16H50/20
    • G16H50/20G06F16/90324G06F16/907G06F17/10G16H50/70
    • A system (500) for automated clinical diagnosis includes: a knowledge graph (310, 510) generated using a curated corpus of medical information (520) and comprising a plurality of nodes; a user interface (512) configured to receive input comprising information about at least one patient symptom (316) and at least one patient demographic parameter (318); and a processor (530) configured to extract the at least one patient symptom and demographic parameter, and further configured to: (i) weight the extracted patient symptom; (ii) query the knowledge graph to generate a diagnosis graph as a subset of the knowledge graph; (iii) identify a ranked list of medical conditions for the patient from the diagnosis graph; and (iv) adjust, based on the extracted at least one demographic parameter about the patient, the ranking of the ranked list; wherein the identified medical conditions are provided to the user via the user interface.
    • 一种用于自动临床诊断的系统(500),包括:使用策划的医疗信息集(520)生成并包括多个节点的知识图(310,510) 用户接口(512),其被配置为接收包括关于至少一个患者症状(316)和至少一个患者人口统计参数(318)的信息的输入; 以及处理器(530),被配置为提取所述至少一个患者症状和人口统计参数,并且还被配置为:(i)对所提取的患者症状加权; (ii)查询知识图以生成作为知识图的子集的诊断图; (iii)从诊断图中识别患者的医疗状况的排序列表; 以及(iv)基于提取的关于患者的至少一个人口统计参数来调整排名列表的排名; 其中识别的医疗状况通过用户界面提供给用户。
    • 4. 发明申请
    • PATIENT-CENTRIC CLINICAL KNOWLEDGE DISCOVERY SYSTEM
    • 以病人为中心的临床知识发现系统
    • WO2018069026A1
    • 2018-04-19
    • PCT/EP2017/074155
    • 2017-09-25
    • KONINKLIJKE PHILIPS N.V.
    • FARRI, Oladimeji, FeyisetanAL HASAN, Sheikh, SadidLIU, JunyiLEE, Kathy, Mi, YoungDATLA, Vivek, Varma
    • G06F19/00G06F17/30G06F17/27
    • G06N5/04G06F16/35G06F17/2785G06N3/08G16H15/00G16H50/20G16H50/70
    • A medical information retrieval system comprises a natural language processing system that processes a vocal user query to identify key words and phrases. These key words and phrases are provided to an inferencing engine that provides a set of knowledge-based inferences from medical knowledge sources, based on these key words and phrases. Thereafter, these knowledge-based inferences are provided to an information retrieval engine that retrieves a corresponding plurality of medical articles based on these knowledge-based inferences, and ranks each with respect to the knowledge-based inferences. A summary engine receives the ranked articles and creates a model based on the topical keywords and candidate sentences found in the highly ranked articles. A paraphrase engine processes the candidate sentences to provide a summary response based on a knowledge-based paraphrase model. An audio output device renders the summary report as the response to the user's original vocal query.
    • 医疗信息检索系统包括处理声音用户查询以识别关键词和短语的自然语言处理系统。 这些关键词和短语被提供给推理引擎,其基于这些关键词和短语提供来自医学知识源的一组基于知识的推论。 此后,将这些基于知识的推论提供给信息检索引擎,该信息检索引擎基于这些基于知识的推论来检索相应的多个医学文章,并且将每个关于基于知识的推论进行排名。 摘要引擎接收排名的文章,并基于在高度排名的文章中找到的主题关键词和候选句子创建模型。 释义引擎处理候选句子以基于基于知识的释义模型提供总结响应。 音频输出设备将摘要报告呈现为对用户原始语音查询的响应。
    • 5. 发明申请
    • KNOWLEDGE DISCOVERY FROM SOCIAL MEDIA AND BIOMEDICAL LITERATURE FOR ADVERSE DRUG EVENTS
    • 来自社交媒体和不良药物事件的生物医学文献的知识发现
    • WO2018036894A1
    • 2018-03-01
    • PCT/EP2017/070814
    • 2017-08-17
    • KONINKLIJKE PHILIPS N.V.
    • LEE, Kathy, Mi, YoungFARRI, Oladimeji, FeyisetanHASAN, Sheikh, Sadid, AlDATLA, Vivek, VarmaLIU, Junyi
    • G06F17/30
    • In adverse drug event (ADE) monitoring and reporting, drug-related messages (60) are detected in one or more social media message streams as messages that include a name of a monitored drug. ADE reports (62) are extracted from the drug-related messages using an ADE classifier (46). The extracted ADE reports are validated by comparison with known ADEs of the monitored drug stored in an ADE knowledge base (64). Extracted ADE reports that fail the validating are collected in a non-validated ADE reports database (72). A report (74) is generated including information on at least one previously unrecognized ADE for which extracted ADE reports in the non-validated ADE reports database satisfy a previously unrecognized ADE criterion (in terms of number of messages or number of unique patients reporting the ADE).
    • 在不良药物事件(ADE)监测和报告中,在一个或多个社交媒体消息流中检测到与药物有关的消息(60)作为包括被监测药物名称的消息。 ADE报告(62)使用ADE分类器从药物相关信息中提取(46)。 提取的ADE报告通过与存储在ADE知识库中的已监测药物的已知ADE进行比较来验证(64)。 提取的ADE报告无法通过未经验证的ADE报告数据库收集验证(72)。 生成报告(74),其包括关于至少一个先前未识别的ADE的信息,未验证的ADE报告数据库中的提取的ADE报告满足先前未识别的ADE标准(根据消息的数量或报告ADE的独特患者的数量 )。
    • 9. 发明申请
    • MULTI DOMAIN REAL-TIME QUESTION ANSWERING SYSTEM
    • 多领域实时问题回答系统
    • WO2018077655A1
    • 2018-05-03
    • PCT/EP2017/076390
    • 2017-10-17
    • KONINKLIJKE PHILIPS N.V.
    • DATLA, Vivek, VarmaAL HASAN, Sheikh, SadidFARRI, Oladimeji, FeyisetanLIU, JunyiLEE, Kathy, Mi, YoungQADIR, AshequlPRAKASH, Adi
    • G06F17/30
    • A system (1000) for automated question answering, including: semantic space (210) generated from a corpus of questions and answers; a user interface (1030) configured to receive a question; and a processor (1100) comprising: (i) a question decomposition engine (1050) configured to decompose the question into a domain, a keyword, and a focus word; (ii) a question similarity generator (1060) configured to identify one or more questions in a semantic space using the decomposed question; (iii) an answer extraction and ranking engine (1080) configured to: extract, from the semantic space, answers associated with the one or more identified questions; and identify one or more of the extracted answers as a best answer; and (iv) an answer tuning engine (1090) configured to fine-tune the identified best answer using one or more of the domain, keyword, and focus word; wherein the fine-tuned answer is provided to the user via the user interface.
    • 一种用于自动问答的系统(1000),包括:从问题和答案的语料库生成的语义空间(210) 用户界面(1030),其被配置为接收问题; 以及处理器(1100),其包括:(i)问题分解引擎(1050),其被配置为将所述问题分解成域,关键词和焦点词; (ii)问题相似度生成器(1060),被配置为使用分解的问题来识别语义空间中的一个或多个问题; (iii)答案提取和排名引擎(1080),其被配置为:从语义空间提取与一个或多个识别的问题相关联的答案; 并将一个或多个提取的答案标识为最佳答案; (iv)回答调整引擎(1090),被配置为使用领域,关键词和焦点词中的一个或多个对所识别的最佳答案进行微调; 其中微调的答案通过用户界面提供给用户。