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1. 发明申请

WO2012104799A1 PLANAR COIL ARRANGEMENT FOR A MAGNETIC INDUCTION IMPEDANCE MEASUREMENT APPARATUS 审中-公开
标题翻译：用于磁感应阻抗测量装置的平面线圈布置
公开(公告)号：WO2012104799A1
公开(公告)日：2012-08-09
申请号：PCT/IB2012/050469
申请日：2012-02-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , ROSELL FERRER, Francisco Javier , IGNEY, Claudia Hannelore , HAMSCH, Matthias
发明人： ROSELL FERRER, Francisco Javier , IGNEY, Claudia Hannelore , HAMSCH, Matthias
IPC分类号： A61B5/05 , G01N27/02
CPC分类号： A61B5/053 , A61B5/0522
摘要： A planar coil arrangement (400) for a magnetic induction impedance measurement apparatus comprises an excitation coil (102) configured for generating a magnetic excitation field in an object, and a detection coil (404) configured for detecting a magnetic response field generated in response to the magnetic excitation field inducing a current in the object. In order to minimize an effect of the magnetic excitation field in the detection coil (404), the detection coil (404) is radially symmetrical shaped with respect to the excitation coil (102) and is arranged relative to the excitation coil (102) such that the magnetic excitation field is minimized in the detection coil (404).
摘要翻译：用于磁感应阻抗测量装置的平面线圈装置（400）包括被配置为在物体中产生磁激励场的激励线圈（102），以及检测线圈（404），被配置为检测响应于励磁场引起物体中的电流。为了最小化检测线圈（404）中的磁激励场的影响，检测线圈（404）相对于励磁线圈（102）是径向对称的，并且相对于励磁线圈（102）布置成在检测线圈（404）中磁激励场被最小化。

2. 发明申请

WO2009138934A1 METHOD AND SYSTEM FOR DETECTING A FLUID DISTRIBUTION IN AN OBJECT OF INTEREST 审中-公开
标题翻译：用于检测物体中流体分布的方法和系统
公开(公告)号：WO2009138934A1
公开(公告)日：2009-11-19
申请号：PCT/IB2009/051908
申请日：2009-05-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , IGNEY, Claudia Hannelore , LANFERMANN, Gerd , HAMSCH, Matthias , VAUHKONEN, Marko Johannes
发明人： IGNEY, Claudia Hannelore , LANFERMANN, Gerd , HAMSCH, Matthias , VAUHKONEN, Marko Johannes
IPC分类号： A61B5/053 , G01V3/10
CPC分类号： G01V3/104 , A61B5/05 , A61B5/0522 , A61B5/4076
摘要： This invention relates to a method and device for detecting a fluid distribution in an object of interest. The method comprises the steps of: (a) measuring (102) magnetic induction signals associated with the object of interest to obtain a first set of measurement data; (b) introducing (104) a conductive contrast agent into the object of interest; (c) measuring (106) magnetic induction signals associated with the object of interest to obtain a second set of measurement data; and (d) calculating (108) a set of parameters based on the first and second sets of measurement data, the set of parameters reflecting a change of conductivity of the fluid distribution in the object of interest. In an embodiment, the method further comprises a step of identifying characteristics reflecting hemorrhagic tissue, ischemic tissue or healthy tissue in the object of interest, based on the set of parameters. (Fig.l)
摘要翻译：本发明涉及一种用于检测感兴趣物体中的流体分布的方法和装置。该方法包括以下步骤：（a）测量（102）与感兴趣对象相关联的磁感应信号以获得第一组测量数据; （b）将导电性造影剂引入（104）到感兴趣的对象中; （c）测量（106）与感兴趣对象相关联的磁感应信号以获得第二组测量数据; 以及（d）基于所述第一和第二组测量数据计算（108）一组参数，所述参数集反映所述感兴趣对象中的流体分布的电导率的变化。在一个实施方案中，该方法还包括基于该组参数来鉴定反映感兴趣对象中的出血组织，缺血组织或健康组织的特征的步骤。（图1）

3. 发明申请

WO2010092503A1 METHOD AND DEVICE FOR MAGNETIC INDUCTION TOMOGRAPHY 审中-公开
标题翻译：用于磁感应造影的方法和装置
公开(公告)号：WO2010092503A1
公开(公告)日：2010-08-19
申请号：PCT/IB2010/050422
申请日：2010-02-01
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , IGNEY, Claudia Hannelore , HAMSCH, Matthias , MAZURKEWITZ, Peter , LUEDEKE, Kai-Michael
发明人： IGNEY, Claudia Hannelore , HAMSCH, Matthias , MAZURKEWITZ, Peter , LUEDEKE, Kai-Michael
IPC分类号： A61B5/05
CPC分类号： A61B5/05 , A61B5/0522
摘要： This invention relates to a method and device for reconstructing images of an object of interest. According to the invention, the device comprises a plurality of transmitting coils (102, 103, 115, 116) for generating a primary magnetic field; a plurality of measurement coils (121, 122, 129, 136); and means (150) for selecting and exciting a first pair of transmitting coils (102, 116) among the plurality of transmitting coils, wherein the first pair of transmitting coils (102, 116) are selected and excited in a way such that the primary magnetic field generated by the first pair of transmitting coils is minimized at the location of at least one measurement coil among the plurality of measurement coils (121, 129). By minimizing the primary magnetic field at the location of the measurement coil(s), the device can reduce the dynamic range of measurement coils, resulting in simplified hardware design for magnetic induction tomography systems.
摘要翻译：本发明涉及一种重建感兴趣对象的图像的方法和装置。根据本发明，该装置包括用于产生初级磁场的多个发射线圈（102,103,115,116）; 多个测量线圈（121,122,129,136）; 以及用于选择和激励所述多个发射线圈中的第一对发射线圈（102,116）的装置（150），其中所述第一对发射线圈（102,116）被选择并激励，使得所述主发射线圈在多个测量线圈（121,129）中的至少一个测量线圈的位置处，由第一对发送线圈产生的磁场最小化。通过使测量线圈位置处的主磁场最小化，该装置可以减少测量线圈的动态范围，从而简化磁感应层析成像系统的硬件设计。

4. 发明申请

WO2010020902A1 METHOD AND DEVICE FOR MAGNETIC INDUCTION TOMOGRAPHY 审中-公开
标题翻译：用于磁感应造影的方法和装置
公开(公告)号：WO2010020902A1
公开(公告)日：2010-02-25
申请号：PCT/IB2009/053460
申请日：2009-08-07
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAUHKONEN, Marko Johannes , IGNEY, Claudia Hannelore , HAMSCH, Matthias , PINTER, Robert , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： VAUHKONEN, Marko Johannes , IGNEY, Claudia Hannelore , HAMSCH, Matthias , PINTER, Robert
IPC分类号： A61B5/053 , G01V3/10
CPC分类号： A61B5/0536 , A61B5/0522 , G01V3/104
摘要： This invention relates to a method and device for magnetic induction tomography. The device comprises a transmitting coil arrangement for generating a primary magnetic field, the primary magnetic field inducing an eddy current in an object of interest, and a measurement coil arrangement for measuring a secondary magnetic field generated by the eddy current to generate a set of measurement data used for image reconstruction of the object of interest, wherein the transmitting coil arrangement at least comprises a pair of transmitting coils intended for carrying substantially electrical currents flowing in the same direction and positioned symmetrically along a common axis and the measurement coil arrangement at least comprises a pair of measurement coils connected and positioned symmetrically along the axis. In an embodiment, the pair of transmitting coils and the pair of measurement coils are respectively Helmholtz coils.
摘要翻译：本发明涉及一种用于磁感应层析成像的方法和装置。该装置包括用于产生初级磁场的发射线圈装置，在感兴趣的物体中感应涡流的初级磁场和用于测量由涡流产生的次级磁场以产生一组测量的测量线圈装置用于感兴趣对象的图像重建的数据，其中发射线圈装置至少包括一对发射线圈，其用于承载沿相同方向流动并基本沿公共轴对称定位的基本电流，并且测量线圈装置至少包括一对测量线圈沿轴线对称地连接和定位。在一个实施例中，一对发射线圈和一对测量线圈分别是亥姆霍兹线圈。

5. 发明申请

WO2012038860A1 METHOD AND ARRANGEMENT FOR GENERATING OXYGEN AND NITRIC OXIDE. 审中-公开
标题翻译：生成氧和氮氧化物的方法和装置。
公开(公告)号：WO2012038860A1
公开(公告)日：2012-03-29
申请号：PCT/IB2011/054018
申请日：2011-09-14
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , HILBIG, Rainer , KOERBER, Achim Gerhard Rolf , IGNEY, Claudia Hannelore
发明人： HILBIG, Rainer , KOERBER, Achim Gerhard Rolf , IGNEY, Claudia Hannelore
IPC分类号： C01B13/02 , C01B21/24
CPC分类号： A61K33/00 , B01D63/00 , C01B13/0251 , C01B21/24 , A61K2300/00
摘要： The invention relates to a Method of generating oxygen and nitric oxide. The method comprises the steps of: guiding an oxygen comprising gas to a primary side of a dense membrane (42), heating the membrane (42) to a temperature at which it is permeable for oxygen, creating a pressure difference between the primary side of the membrane (42) and a secondary side of the membrane (42), wherein a stream of oxygen is generated at the secondary side of the membrane (42) and a stream of oxygen depleted gas is generated at the primary side of the membrane (42). The method according to the invention further comprises the steps of: providing a flow of nitrous oxide comprising gas and heating the nitrous oxide comprising gas to a temperature at which nitric oxide is generated. Thereby, according to the invention, heat generated in the process of operating the membrane is used. According to the invention it is possible to generate both oxygen and nitric oxide in one device making use of several synergistic effects, thus being energy saving.
摘要翻译：本发明涉及产生氧和一氧化氮的方法。该方法包括以下步骤：将含氧气体引导到致密膜（42）的初级侧，将膜（42）加热至可渗透氧气的温度，从而产生压力差膜（42）和膜（42）的次级侧，其中在膜（42）的次级侧产生氧气流，并且在膜的初级侧产生贫氧气体流（ 42）。根据本发明的方法还包括以下步骤：提供包含气体的一氧化二氮流并将包含一氧化二氮的气体加热至产生一氧化氮的温度。因此，根据本发明，使用在操作膜的过程中产生的热量。根据本发明，可以在一个使用几种协同效应的装置中产生氧和一氧化氮，从而节能。

6. 发明申请

WO2011077327A2 METHOD FOR GENERATING NITRIC OXIDE 审中-公开
标题翻译：生成氮氧化物的方法
公开(公告)号：WO2011077327A2
公开(公告)日：2011-06-30
申请号：PCT/IB2010/055856
申请日：2010-12-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , HILBIG, Rainer , PINTER, Robert , IGNEY, Claudia Hannelore
发明人： HILBIG, Rainer , PINTER, Robert , IGNEY, Claudia Hannelore
IPC分类号： C01B21/30
CPC分类号： C01B21/30 , A61K33/00 , A61M16/10 , A61M2202/0208 , A61M2202/0275
摘要： The invention relates to a method for generating nitric oxide, in particular for therapeutic applications, which comprises the steps of: guiding a process gas into a reaction chamber 3, wherein the process gas comprises nitrogen and oxygen, heating the process gas to a temperature which is sufficiently high to enable a reaction of oxygen and nitrogen to form nitric oxide, thereby forming a gas which comprises nitric oxide, and extracting the nitric oxide comprising gas from the reaction chamber 3, wherein oxygen is present in the process gas in the reaction chamber in an amount of
摘要翻译：本发明涉及一种用于产生一氧化氮的方法，特别是用于治疗应用，其包括以下步骤：将工艺气体引导到反应室3中，其中工艺气体包括氮和氧，将工艺气体加热至足够高以使氧和氮反应形成一氧化氮，从而形成包含一氧化氮的气体，并从反应室3中提取包含气体的一氧化氮，其中氧气存在于反应室中的工艺气体中数量<5vol-％。

7. 发明申请

WO2010097726A1 A MAGNETIC INDUCTION TOMOGRAPHY SYSTEM 审中-公开
标题翻译：磁感应造影系统
公开(公告)号：WO2010097726A1
公开(公告)日：2010-09-02
申请号：PCT/IB2010/050599
申请日：2010-02-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , YAN, Ming , LIU, Hui , JIN, Hua , CHEN, Dayu , KROON, Ron , IGNEY, Claudia Hannelore , VAUHKONEN, Marko, Johannes
发明人： YAN, Ming , LIU, Hui , JIN, Hua , CHEN, Dayu , KROON, Ron , IGNEY, Claudia Hannelore , VAUHKONEN, Marko, Johannes
IPC分类号： A61B5/05
CPC分类号： A61B5/05 , A61B5/0522 , A61B5/6814 , A61B5/6833 , A61B2562/164
摘要： The invention provides a magnetic induction tomography system (20) comprising: - an adaptive unit (21) arranged for detecting an electromagnetic signal from an object (30), wherein the adaptive unit (21) is adaptive to the shape of the object (30) for closely contacting the object (30); and - a main unit (23) for processing the electromagnetic signal received from the adaptive unit (21) through a connecting unit (22).
摘要翻译：本发明提供一种磁感应断层摄影系统（20），包括：自适应单元（21），被配置为检测来自物体（30）的电磁信号，其中所述自适应单元（21）适应于所述物体（30）的形状）用于紧密接触物体（30）; 以及 - 用于通过连接单元（22）处理从自适应单元（21）接收的电磁信号的主单元（23）。

8. 发明申请

WO2012114235A1 METHOD AND ARRANGEMENT FOR GENERATING A GAS STREAM COMPRISING NITRIC OXIDE 审中-公开
标题翻译：用于产生包含氮氧化物的气体流的方法和装置
公开(公告)号：WO2012114235A1
公开(公告)日：2012-08-30
申请号：PCT/IB2012/050716
申请日：2012-02-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , IGNEY, Claudia Hannelore , KOERBER, Achim , HILBIG, Rainer
发明人： IGNEY, Claudia Hannelore , KOERBER, Achim , HILBIG, Rainer
IPC分类号： A61M16/00 , A61M16/12
CPC分类号： A61M16/12 , A61M16/00 , A61M2202/0208 , A61M2202/0275
摘要： The invention relates to the field of nitric oxide generation. The present invention particularly relates to a method for generating a stream of gas, the gas comprising oxygen and nitric oxide. According to the invention, an intermittent stream of oxygen comprising gas having at least one gap is provided, in which gap a defined pulse of nitric oxide comprising gas is provided. The pulse of nitric oxide comprising gas is embedded in a first pulse of inert gas being provided before the pulse of nitric oxide comprising gas and a second pulse of inert gas being provided after the pulse of nitric oxide comprising gas, the first pulse of inert gas and the second pulse of inert gas being provided in the gap of the intermittent stream of oxygen comprising gas. The method according to the invention reduces the danger of toxic compounds to be formed in the generated gas stream and furthermore provides a method being usable for therapeutic applications independent from the breathing cycle of a patient.
摘要翻译：本发明涉及一氧化氮生成领域。本发明特别涉及一种产生气流的方法，所述气体包括氧和一氧化氮。根据本发明，提供了包含具有至少一个间隙的气体的间歇性氧气流，其中提供了包含气体的一定氧化物脉冲。在包含气体的一氧化氮脉冲之后，在包含气体的一氧化氮的脉冲之后，提供包含气体的一氧化氮的脉冲，该惰性气体的第一脉冲是在包含气体的一氧化氮的脉冲之前提供的，第一脉冲的惰性气体脉冲并且第二脉冲的惰性气体设置在包含气体的间歇氧气流的间隙中。根据本发明的方法降低了在产生的气流中形成的有毒化合物的危险性，并且还提供了可独立于患者呼吸循环的治疗应用的方法。

9. 发明申请

WO2008015598A3 SENSOR FOR DETECTING THE PASSING OF A PULSE WAVE FROM A SUBJECT´S ARTERIAL SYSTEM 审中-公开
公开(公告)号：WO2008015598A3
公开(公告)日：2008-02-07
申请号：PCT/IB2007/052763
申请日：2007-07-11
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N.V. , MÜHLSTEFF, Jens , IGNEY, Claudia Hannelore , THIJS, Jeroen Adrianus Johannes , PINTER, Robert
发明人： MÜHLSTEFF, Jens , IGNEY, Claudia Hannelore , THIJS, Jeroen Adrianus Johannes , PINTER, Robert
IPC分类号： A61B5/02
摘要： In order to provide an easy-to-use technique for measuring blood pressure and/or other vital signs of a subject, a sensor for detecting the passing of a pulse wave from a subject's arterial system is suggested, the sensor being adapted to be located at a sensing position on the exterior of the subject's body, characterized in that the sensor comprises a number of electrical coils for generating an inductive coupling to the subject's body in a way that the properties of said inductive coupling change if a pulse wave passes a screened volume underneath the sensing position, and a circuit connected to the number of electrical coils, said circuit being adapted to detect said property changes of the inductive coupling.

10. 发明申请

WO2007029138A2 SYSTEM AND METHOD FOR INDUCTIVELY MEASURING THE BIO-IMPEDANCE OF A CONDUCTIVE TISSUE 审中-公开
标题翻译：用于诱导测量导电组织的生物阻抗的系统和方法
公开(公告)号：WO2007029138A2
公开(公告)日：2007-03-15
申请号：PCT/IB2006/052979
申请日：2006-08-28
申请人： PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , KONINKLIJKE PHILIPS ELECTRONICS N. V. , IGNEY, Claudia Hannelore , WAFFENSCHMIDT, Eberhard , BRAUERS, Andreas , TE VRUGT, Juergen
发明人： IGNEY, Claudia Hannelore , WAFFENSCHMIDT, Eberhard , BRAUERS, Andreas , TE VRUGT, Juergen
IPC分类号： A61B5/053 , G01N27/02 , G01N27/90
CPC分类号： A61B5/053
摘要： The present invention relates to a system (100) and method of inductively measuring the bio-impedance of a conductive tissue (106). Furthermore the invention relates to a computer program (115) for operating such a system (100). In order to provide a fast, simple and reliable adjustment technique for an inductively bio- impedance measuring system (100) with separate generator and sensor coils (101, 108; 117) a system (100) is suggested, the system (100) comprising a generator coil (101) adapted for generating a primary magnetic field, said primary magnetic field inducing an eddy current in the conductive tissue (106), a separate sensor coil (108; 117) adapted for sensing a secondary magnetic field, said secondary magnetic field being generated as a result of said eddy current, with the axis (109) of the sensor coil (108; 117) being orientated substantially perpendicular to the flux lines of the primary magnetic field (103), and a shimming coil (113; 120) adapted for generating a tertiary magnetic field in a way that in the sensor coil (108; 117) the primary magnetic field is cancelled out.
摘要翻译：感测测量导电组织（106）的生物阻抗的系统（100）和方法技术领域本发明涉及感应测量导电组织（106）的生物阻抗的系统（100）和方法。此外，本发明涉及用于操作这种系统（100）的计算机程序（115）。为了为具有单独的发生器和传感器线圈（101,108; 117）的感应生物阻抗测量系统（100）提供快速，简单和可靠的调节技术，建议系统（100），系统（100）包括适于产生主磁场的发生器线圈（101），所述主磁场在所述导电组织（106）中感应出涡电流，单独的传感器线圈（108; 117）适于感测次级磁场，所述次级磁场所述传感器线圈（108; 117）的轴线（109）基本上垂直于所述主磁场（103）的磁通线而定向，并且所述涡电流产生于所述涡电流的结果，以及匀场线圈（113; 120），适合于以在传感器线圈（108; 117）中主磁场被抵消的方式产生第三磁场。

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