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    • 2. 发明申请
    • PET IMAGING USING ANATOMIC LIST MODE MASK
    • PET成像使用解剖列表模式掩模
    • WO2007054843A1
    • 2007-05-18
    • PCT/IB2006/053824
    • 2006-10-17
    • KONINKLIJKE PHILIPS ELECTRONICS, N.V.GAGNON, DanielWANG, WenliHU, Zhiqiang
    • GAGNON, DanielWANG, WenliHU, Zhiqiang
    • G01T1/29G06T11/00
    • G01T1/2985A61B6/037G01T1/1611G06T11/006G06T2211/424
    • A method and apparatus are provided for reconstructing list mode data acquired during a positron emission tomography scan of an object, the data including information indicative of a plurality of detected positron annihilation events. Detected events occurring in a region of interest are identified; the identified events are reconstructed using an iterative reconstruction technique which includes a ray tracing operation to generate volumetric data indicative of the region of interest, wherein the ray tracing operation traces only image matrix elements located in the region of interest; and a human readable image indicative of the volumetric data is generated. In another aspect an image mask and a projection mask are defined correlating to the region of interest; image matrix elements located in the region of interest are determined by applying the image mask; and detected events occurring in a region of interest are identified by applying the projection mask.
    • 提供了一种方法和装置,用于重构在对象的正电子发射断层摄影扫描期间获取的列表模式数据,该数据包括指示多个检测到的正电子湮灭事件的信息。 确定在感兴趣区域发生的检测事件; 使用迭代重建技术来重建所识别的事件,所述迭代重建技术包括用于产生指示感兴趣区域的体积数据的光线跟踪操作,其中光线跟踪操作仅跟踪位于感兴趣区域中的图像矩阵元素; 并产生指示体积数据的人类可读取的图像。 在另一方面,图像掩模和投影掩模被定义为与感兴趣区域相关; 通过应用图像掩模来确定位于感兴趣区域中的图像矩阵元素; 并且通过应用投影掩模来识别在感兴趣区域中发生的检测到的事件。
    • 3. 发明申请
    • METHOD AND SYSTEM FOR PET IMAGE RECONSTRUCTION USING PORTION OF EVENT DATA
    • 使用事件数据部分进行PET图像重构的方法和系统
    • WO2007052211A1
    • 2007-05-10
    • PCT/IB2006/054013
    • 2006-10-30
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.GAGNON, DanielKOLTHAMMER, Jeffrey, A.
    • GAGNON, DanielKOLTHAMMER, Jeffrey, A.
    • G06T11/00
    • A61B6/037G06T11/006
    • A method and system for use in positron emission tomography, wherein a list-based reconstructor means (129) is configured to generate first portion volumetric data responsive to a first portion of a plurality of positron annihilation events detected during a positron emission tomography scan; generate a human-readable image indicative of the first portion volumetric data; use a list-based reconstruction technique to generate composite volumetric data responsive to the first portion volumetric data and a second portion of the plurality of positron annihilation events; and generate a composite human-readable image indicative of the composite volumetric data. In another aspect the reconstructor (129) is configured to selecting first or second portion event quantities responsive to one or more parameters including image definition requirements and processing time requirements.
    • 一种用于正电子发射断层摄影的方法和系统,其中基于列表的重建器装置(129)被配置为响应于在正电子发射断层摄影扫描期间检测到的多个正电子湮灭事件的第一部分而产生第一部分体积数据; 生成指示第一部分体积数据的人类可读图像; 使用基于列表的重建技术来响应于第一部分体积数据和多个正电子湮灭事件的第二部分来生成复合体积数据; 并生成指示复合体积数据的复合人类可读图像。 在另一方面,重建器(129)被配置为响应于包括图像定义要求和处理时间要求的一个或多个参数来选择第一或第二部分事件量。
    • 5. 发明申请
    • OPTIMAL CONVERSION OF 3D IMAGE SETS BETWEEN DIFFERENT SPACES
    • 三维图像集在不同空间之间的最优转换
    • WO2006054193A1
    • 2006-05-26
    • PCT/IB2005/053630
    • 2005-11-04
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.GAGNON, DanielWANG, Wenli
    • GAGNON, DanielWANG, Wenli
    • G06T3/00
    • G06T3/4061A61B6/583
    • A multi-modality system (10) includes a nuclear imaging system (12) and a computed tomography (CT) scanner (14). The nuclear system (12) includes a PET scanner (28) which acquires electronic data that is reconstructed into a PET blob image by a PET reconstruction processor (50). The CT scanner (14) acquires the scanned data which is reconstructed into a 3D CT voxel image by a CT reconstruction processor (56). An interpolation processor (62) interpolates the PET blob image directly into the CT voxel space. Once the PET and CT images are in the same space, they are combined by a combining means (110). A video processor (66) processes the received composite PET-CT data for a display on a monitor (68).
    • 多模态系统(10)包括核成像系统(12)和计算机断层摄影(CT)扫描器(14)。 核系统(12)包括PET扫描器(28),其通过PET重建处理器(50)获取被重建为PET斑点图像的电子数据。 CT扫描器(14)通过CT重建处理器(56)获取重建成3D CT体素图像的扫描数据。 插值处理器(62)将PET斑点图像直接内插到CT体素空间中。 一旦PET和CT图像在相同的空间中,它们通过组合装置(110)组合。 视频处理器(66)处理所接收的复合PET-CT数据以用于监视器(68)上的显示。
    • 6. 发明申请
    • MR SEGMENTATION USING TRANSMISSION DATA IN HYBRID NUCLEAR/MR IMAGING
    • 在混合核/ MR成像中使用传输数据的MR分段
    • WO2010032167A2
    • 2010-03-25
    • PCT/IB2009/053944
    • 2009-09-09
    • KONINKLIJKE PHILIPS ELECTRONICS, N.V.GAGNON, DanielHU, Zhiquiang
    • GAGNON, DanielHU, Zhiquiang
    • G01R33/481G01R33/5608G06T7/11G06T2207/10088G06T2207/10104G06T2207/30004
    • When correcting attenuation in a nuclear image (e.g., PET or SPECT), an MR-based attenuation correction (AC) map (16) is generated using MR image data (14) of a subject (60). The subject (60) is then placed in a nuclear imaging device with a radioactive point or line source (18, 18') from which transmission data is measured as the patient is imaged. In order to resolve ambiguity between air voxels and bone voxels in the MR-based AC map (16), estimated transmission data (24) is generated from the AC map and compared to the measured transmission data (22) from the point or line source. An error is iteratively calculated for the estimated and measured transmission data, and attenuation values of the AC map (16) are refined to minimize the error. The refined AC map (32) is used to correct attenuation in collected nuclear data (41) which is reconstructed into an attenuation corrected image (99) of the patient.
    • 当校正核图像(例如PET或SPECT)中的衰减时,使用对象(60)的MR图像数据(14)来生成基于MR的衰减校正(AC)图(16)。 然后将受试者(60)放置在具有放射性点或线源(18,18')的核成像装置中,当患者被成像时,将从该成像装置测量透射数据。 为了解决基于MR的AC映射(16)中的空气体素和骨骼体素之间的模糊性,从AC映射产生估计的传输数据(24),并与来自点或线源的测量的传输数据(22)进行比较 。 对估计和测量的传输数据迭代地计算误差,并且AC图(16)的衰减值被改进以使误差最小化。 精细AC图(32)用于校正收集的核数据(41)中的衰减,其被重建为患者的衰减校正图像(99)。
    • 8. 发明申请
    • GEOMETRICAL TRANSFORMATIONS PRESERVING LIST-MODE FORMAT
    • 几何变换保存列表模式格式
    • WO2009144607A2
    • 2009-12-03
    • PCT/IB2009/051987
    • 2009-05-13
    • KONINKLIJKE PHILIPS ELECTRONICS, N.V.GAGNON, DanielOLIVIER, PatrickKHURD, Parmeshwar, Kishore
    • GAGNON, DanielOLIVIER, PatrickKHURD, Parmeshwar, Kishore
    • G01T1/1648A61B6/037G06T11/005
    • A diagnostic imaging device includes detector elements (16) for detecting γ- rays indicative of nuclear decay events. The detected γ-rays are used to produce lines of response (LORs) (46), which are time stamped (20) and stored in list mode. The LORs are reconstructed (34) into an image. An image analysis processor (38) analyzes the image for motion artifacts and iteratively adjusts an event transform processor (30) to transform selected LORs to minimize the motion artifacts. If the transformed LOR (50) does not correspond with a pair of detector elements (16), closest detector elements (52, 54) are determined. Candidate LORs (62) are created between the closest and neighboring detector elements. An event location (40) on an LOR (46) is determined from the time-of- flight (TOF) information and then transformed (47) to generate a transformed event location (48). The candidate LOR (62) which most nearly intersects the transformed event location (40) and the appropriately updated TOF information is selected for use in image reconstruction.
    • 诊断成像装置包括用于检测指示核衰变事件的γ射线的检测器元件(16)。 检测到的γ射线用于产生响应列(LOR)(46),它们是时间戳的(20)并以列表模式存储。 LOR被重构(34)成为图像。 图像分析处理器(38)分析运动伪影的图像并迭代地调整事件变换处理器(30)以变换所选择的LOR以最小化运动伪影。 如果变换的LOR(50)不对应于一对检测器元件(16),则确定最近的检测器元件(52,54)。 在最近和相邻的检测器元件之间创建候选LOR(62)。 从飞行时间(TOF)信息确定LOR(46)上的事件位置(40),然后变换(47)以生成转换的事件位置(48)。 选择与变换的事件位置(40)最接近相交的候选LOR(62)和适当更新的TOF信息用于图像重建。
    • 9. 发明申请
    • ASYMMETRIC AXIAL FILTER FOR PET IMAGING SYSTEMS
    • PET成像系统的不对称轴向过滤器
    • WO2005071439A1
    • 2005-08-04
    • PCT/IB2005/050058
    • 2005-01-05
    • KONINKLIJKE PHILIPS ELECTRONICS, N.V.GAGNON, DanielKOLTHAMMER, Jeffrey, A.
    • GAGNON, DanielKOLTHAMMER, Jeffrey, A.
    • G01T1/29
    • G01T1/2985A61B6/037G01T1/1615
    • A radiographic imaging system (10) includes an array of detectors (16) for detecting emission radiation emitted from a subject (14). The detectors (16) are arranged around a circular bore (18), defining a field of view of the imaging system (10). End shields (40) are disposed at an entrance and at an exit of the axial field-of-view (18) defining a subject receiving aperture (46). One or more septa (50), partially covering the circumference, shields the detectors (16) from the radiation originating outside of the axial field-of-view (18) as well as the body scattered radiation. Septa (50) are spread out sparsely across the field of view such that a ratio of the area shielded by the septa (50) to the field of view is negligible. The patient aperture (46) is increased without compromising the 3D imaging.
    • 射线照相成像系统(10)包括用于检测从被摄体(14)发射的发射辐射的检测器阵列(16)。 检测器(16)绕圆形孔(18)布置,限定成像系统(10)的视场。 端面罩(40)设置在限定被摄体接收孔(46)的轴向视场(18)的入口处和出口处。 部分覆盖圆周的一个或多个隔片(50)将来自位于轴向视野(18)外部的辐射以及身体散射辐射屏蔽到检测器(16)。 隔垫(50)在视野范围内稀疏地分布,使得隔膜(50)屏蔽的面积与视场的比率可以忽略不计。 病人孔径(46)增加而不损害3D成像。