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    • 1. 发明申请
    • MAGNETIC SENSOR DEVICE WITH SUPPRESSION OF SPURIOUS SIGNAL COMPONENTS
    • 具有抑制SPUIOUS信号组件的磁传感器装置
    • WO2008075262A3
    • 2008-08-21
    • PCT/IB2007055057
    • 2007-12-12
    • KONINKL PHILIPS ELECTRONICS NVKAHLMANN JOSEPHUS A H MDE BOER BART MJANSEN THEODORUS P H GVEEN JEROEN
    • KAHLMANN JOSEPHUS A H MDE BOER BART MJANSEN THEODORUS P H GVEEN JEROEN
    • G01N33/543G01R33/09G01R33/12
    • G01R33/093B82Y25/00G01R33/1269
    • The invention relates to a magnetic sensor device for the determination of magnetized particles (3) which comprises a magnetic field generator (1, 1') (e.g. a conductor wire) that is driven with an excitation current (I I ) of a first frequency (f 1 ), and a magnetic sensor element (2) (e.g. a GMR resistance), that is driven with a sensor current (I 2 ) of a second frequency (f 2 ) for generating measurement signals (U GMR ). A preprocessed signal (uf) is then generated from the measurement signal (U GMR ) that comprises a predetermined frequency (?f), and an evaluation unit (10) separates from this preprocessed signal a spurious component that does not depend on the presence of magnetized particles (3) in the sample chamber. The spurious component (U Q ) may particularly be caused by self-magnetization (H 2 ) of the magnetic sensor element (2) in combination with parasitic (capacitive or inductive) cross-talk. Furthermore, an unknown, variable phase-shift (f SP ) in the preprocessed signal (u f ) may be determined by varying the ratio between the spurious component and a particle-dependent target component. This variation may for example be achieved if, in an optimization stage (OS), the excitation current (I 1 ) is conducted through a bypass resistor (R, R') and/or if an additional capacitor is introduced between the magnetic field generator and the magnetic sensor element. The determined phase shift can then be used to adjust the phase of a demodulation signal (u dem ) such that the spurious component is suppressed.
    • 本发明涉及一种用于确定磁化颗粒(3)的磁传感器装置,其包括用激励电流(I I')驱动的磁场发生器(1,1')(例如导线) 第一频率(f 1> 1)的磁传感器元件(2)(例如GMR电阻),以及传感器电流(I 2 2 / >)用于产生测量信号(U SUB GMR)的第二频率(f 2> 2)。 然后,从包括预定频率(Δf)的测量信号(U SUB GMR)产生预处理信号(uf),并且评估单元(10)从该预处理信号中分离出杂散分量, 不依赖于样品室中磁化颗粒(3)的存在。 杂散分量(U SUB)可以特别地由磁传感器元件(2)的自磁化(H 2 2 N)与寄生(电容或电感)组合引起。 相声。 此外,预处理信号(u> f>)中的未知的可变相移(f SP SP)可以通过改变杂散分量和粒子 - 依赖目标成分。 例如,如果在优化级(OS)中通过旁路电阻(R,R')传导激励电流(I,1')和/或如果附加电容器 介于磁场发生器和磁传感器元件之间。 然后可以使用所确定的相移来调整解调信号的相位,使得杂散分量被抑制。
    • 2. 发明申请
    • MAGNETIC SENSOR DEVICE WITH ROBUST SIGNAL PROCESSING
    • 具有稳健信号处理的磁性传感器装置
    • WO2008075274A3
    • 2008-08-21
    • PCT/IB2007055114
    • 2007-12-14
    • KONINKL PHILIPS ELECTRONICS NVVEEN JEROENJANSEN THEODORUS P H GDE BOER BART MKAHLMAN JOSEPHUS A H M
    • VEEN JEROENJANSEN THEODORUS P H GDE BOER BART MKAHLMAN JOSEPHUS A H M
    • G01N33/543G01R33/09G01R33/12
    • G01R33/093B82Y25/00G01R33/1269
    • The invention relates to a magnetic sensor device (100) comprising a magnetic field generator (1) driven with an excitation current of a first frequency (f 1 ) and a magnetic sensor element (e.g. a GMR sensor (2)) driven with a sensor current (I 2 ) of a second frequency (f 2 ) for measuring reaction fields (H B ) generated by magnetized particles (3). In an associated evaluation unit (10), a reference component (u Q ) of the measurement signal (u GMR ) is separated that depends on the excitation current (I 1 ) and the sensor current (I 2 ) but not on the presence of magnetized particles (3). The reference component (u Q ) may particularly be produced by a combination of the self- magnetization (H 2 ) of the magnetic sensor element (2) and cross-talk related currents. The reference component (u Q ) may be isolated based on its phase with respect to a particle-dependent component of the measurement signal (u GMR ) or based on its scaling with one of the current frequencies. Monitoring of the reference component (u Q ) reveals variations in operating conditions, for example in the sensor gain, that can be used to calibrate the measurement results.
    • 本发明涉及一种磁传感器装置(100),该磁传感器装置(100)包括利用第一频率(f 1)的激励电流驱动的磁场发生器(1)和磁传感器元件(例如GMR传感器 2))以第二频率(f 2 )的传感器电流(I 2 )驱动,以测量产生的反应场(H B ) 通过磁化粒子(3)。 在相关的评估单元(10)中,测量信号(u GMR )的参考分量(u Q )被分开,其取决于激励电流(I 1 )和传感器电流(I 2 ),但不存在磁化粒子(3)。 特别地,参考分量(u Q)可以通过磁传感器元件(2)的自磁化(H 2 SUB)和串扰相关 电流。 可以基于其相对于测量信号的微粒相关分量(u GMR )的相位或基于其相对于其测量信号的缩放来隔离参考分量(u Q 当前频率之一。 监测参考组分(u Q )可以发现运行条件的变化,例如传感器增益,可用于校准测量结果。
    • 3. 发明申请
    • SENSOR DEVICE FOR TARGET PARTICLES IN A SAMPLE
    • 传感器装置在样品中的目标颗粒
    • WO2009053902A3
    • 2009-12-10
    • PCT/IB2008054329
    • 2008-10-21
    • KONINKL PHILIPS ELECTRONICS NVVERSCHUREN COEN AKAHLMAN JOSEPHUS A H MIMMINK ALBERT H JMEGENS MISCHAVEEN JEROENDE BOER BART MJANSEN THEODORUS P H G
    • VERSCHUREN COEN AKAHLMAN JOSEPHUS A H MIMMINK ALBERT H JMEGENS MISCHAVEEN JEROENDE BOER BART MJANSEN THEODORUS P H G
    • G01N15/06
    • G01N15/06G01N15/0656G01N2015/0693G01R33/1269
    • The invention relates to a sensor device(100) and a method for the determination of the amount of target particles(1) at a contact surface(112) adjacent to a sample chamber(2). Target particles(1) in the sample chamber are detected by a sensor element(SE) and at least one corresponding sensor-signal (s, s') is provided. An evaluation unit(EU) then determines the amount of target particles(1) in a first zone(Z1) immediately at the contracts surface(112) and a second zone(Z2) a distance(z) away from the contact surface based on this sensor-signal. In an optical measurement approach, frustrated total internal reflection taking place under different operating conditions (e.g. wavelength, angle of incidenceq) may be used to extract information about the first and second zones(Z1, Z2). In a magnetic measurement approach, different magnetic excitation fields may be used to excite magnetic target particles differently inthe first and second zone(Z2). Moreover, the temporalcourse of a sensor-signal(s, s') can be evaluated, particularly with respect to stochastic movements ofthe target particles(1).
    • 本发明涉及一种传感器装置(100)和用于确定在与样品室(2)相邻的接触表面(112)处的目标颗粒(1)的量的方法。 通过传感器元件(SE)检测样品室中的目标颗粒(1),并提供至少一个对应的传感器信号(s,s')。 然后,评估单元(EU)基于紧接表面(112)立即确定第一区域(Z1)中的目标颗粒(1)的数量和远离接触表面的距离(z)的第二区域(Z2),基于 这个传感器信号。 在光学测量方法中,可以使用在不同操作条件(例如,波长,入射角q)处发生的沮丧的全内反射来提取关于第一和第二区域(Z1,Z2)的信息。 在磁测量方法中,可以使用不同的磁激励场来在第一和第二区(Z2)中不同地激励磁性目标颗粒。 此外,可以评估传感器信号(s,s')的时间,特别是关于目标颗粒(1)的随机运动。
    • 4. 发明申请
    • A METHOD FOR CALIBRATING A TRANSFER FUNCTION OF A MAGNETIC SENSOR
    • 一种用于校准磁传感器的传递函数的方法
    • WO2006059268A3
    • 2006-10-12
    • PCT/IB2005053930
    • 2005-11-28
    • KONINKL PHILIPS ELECTRONICS NVKAHLMAN JOSEPHUS A H MDE BOER BART M
    • KAHLMAN JOSEPHUS A H MDE BOER BART M
    • G01N27/74G01N33/543
    • G01R33/093B82Y25/00G01R33/1269
    • A method for calibrating a transfer function of a magnetic sensor (MS) on a substrate (SBSTR) in which sensor (MS) the presence of magnetizable objects (SPB) can be detected by magnetizing the objects (SPB) by a magnetic field (H) delivered by a magnetic field generator (WR 1 , WR 2 ) and in which the transfer function is defined as the transfer from an electrical input signal (I in ) for generating the magnet field H, via magnetic stray field (SF) radiated by the objects (SPB) when magnetized, to an electrical output signal (I out ) delivered by the sensor (MS), comprising the steps of: - putting sample fluid on the substrate (SBSTR), the sample fluid comprising a large amount of the magnetizable objects (SPB), - attracting part of the magnetizable objects (SPB) towards the magnetic sensor (MS), - activating the electrical input signal (I in ), thereby generating the magnet field (H), - measuring the electrical output signal (I out ) as a response to the electrical input signal (I in ), - calculating the transfer function from the electrical input and output signals (I in , I out ).
    • 用于校准传感器(MS)的磁传感器(MS)的传递函数的方法,其中传感器(MS)可磁化物体(SPB)的存在可以通过用磁场(H)磁化物体(SPB)来检测 ),并且其中传递函数被定义为从电输入信号(I< 1> 2> 用于通过被磁化时被物体(SPB)辐射的磁性杂散场(SF)产生磁场H以产生由传感器传送的电输出信号(I OUT)的磁场H(< / SUB> MS),包括以下步骤: - 将样品流体放置在基底(SBSTR)上,样品流体包含大量可磁化物体(SPB), - 将可磁化物体(SPB)的一部分吸引到磁传感器(MS ), - 激活电输入信号(中的I ),从而产生磁场(H), - 测量电输出信号(I SUB) >)作为对电输入信号(I 中的)的响应, - 从电输入和输出信号(I SUB)中计算传递函数,I )。
    • 5. 发明申请
    • MEANS AND METHOD FOR REDUCING MAGNETIC CROSS-TALK IN BIOSENSORS
    • 用于在生物传感器中减少磁性交叉的手段和方法
    • WO2006067646A3
    • 2006-10-12
    • PCT/IB2005053933
    • 2005-11-28
    • KONINKL PHILIPS ELECTRONICS NVKAHLMAN JOSEPHUS A H MDE BOER BART M
    • KAHLMAN JOSEPHUS A H MDE BOER BART M
    • G01N27/72G01R33/09
    • G01R33/093B82Y25/00G01R33/1269
    • A magnetic sensor (MS) for sensing a magnetic stray field (SF) generated by magnetizable object (SPB) when magnetized and for generating an electrical object signal (U OB ) which depends on the sensed magnetic stray field (SF), comprising a magnetic field generator (WR 1 , WR 2 ) for generating a magnetic main field (H) for magnetizing the magnetizable object (SPB), and cross-talk reduction means for reducing the effect of a cross talk signal component in the electrical object signal (U OB ) caused by magnetic cross-talk between the magnetic main field (H) and the magnetic stray field (SF), wherein the cross-talk reduction means is arranged for distinguishing a signal property between the cross-talk signal component and the remaining part of the electrical object signal (U OB ) and for generating an electrical output signal (U o ).
    • 一种用于感测磁化物体(SPB)产生的磁性杂散场(SF)的磁性传感器(MS),其被磁化并用于产生取决于感测的磁性杂散场的电气对象信号(U OB OB) (SF),包括用于产生用于磁化可磁化物体(SPB)的磁性主场(H)的磁场发生器(WR 1,W 2 S 2),并且交叉 - 减速装置,用于降低由磁性主场(H)和磁性杂散场(H)与磁性杂散场(H)之间的磁串扰引起的电气对象信号(U OB OB)中串扰信号分量的影响 SF),其中所述串扰减少装置被布置用于区分串扰信号分量与电对象信号的剩余部分(U OB OB)之间的信号特性,并用于产生电输出 信号(U o o)。
    • 6. 发明申请
    • DEVICE COMPRISING A MAGNETO RESISTIVE SYSTEM
    • 包含磁阻系统的器件
    • WO2007010464A3
    • 2007-07-19
    • PCT/IB2006052416
    • 2006-07-14
    • KONINKL PHILIPS ELECTRONICS NVVAN ZON HANSDE BOER BART M
    • VAN ZON HANSDE BOER BART M
    • G01R33/09
    • G01R33/09G01R33/096
    • Devices (1) comprising magneto resistive systems (2) for detecting incoming magnetic fields and comprising first/second branches with first/second magneto resistive elements (21-22) having first/second resistance values depending on the incoming magnetic fields according to first/second response curves are provided with shifting means for shifting the first/second response curves of the first/second branches into first/second directions to get an adapted linear behavior. The shifting means comprise first/second structures of the first/second branches resulting in a first/second local fields at the first/second branches such that the first/second response curves of the first/second branches are shifted into the first/second directions. The first/second branches comprise further first/second magneto resistive elements (26b,26c,27b,27c) coupled to the first/second magneto resistive elements (26a,27a) such that first/second currents flowing through these first/second magneto resistive elements (26a-26c,27a-27c) result in the first/second local fields at the first/second branches. The first/second structures comprise first/second meander structures (36,37) wherein first/second parts (36a-36c,37a-37c) comprise different first sizes such as alternating first/second widths.
    • 包括用于检测输入磁场的磁阻系统(2)并且包括具有第一/第二电阻值的第一/第二支路(21-22)的装置(1),所述第一/第二电阻值取决于根据第一/ 第二响应曲线设置有用于将第一/第二分支的第一/第二响应曲线移位到第一/第二方向以获得适应的线性行为的移位装置。 移位装置包括第一/第二分支的第一/第二结构,从而在第一/第二分支处产生第一/第二局部场,使得第一/第二分支的第一/第二响应曲线移位到第一/第二方向 。 第一/第二分支包括耦合到第一/第二磁阻元件(26a,27a)的另外的第一/第二磁阻元件(26b,26c,27b,27c),使得流过这些第一/第二磁阻 元件(26a-26c,27a-27c)在第一/第二分支处产生第一/第二局部场。 第一/第二结构包括第一/第二曲折结构(36,37),其中第一/第二部分(36a-36c,37a-37c)包括不同的第一尺寸,例如交替的第一/第二宽度。
    • 7. 发明申请
    • MEANS AND METHOD FOR SENSING A MAGNETIC STRAY FIELD IN BIOSENSORS
    • 用于感应生物传感器中磁场的方法和方法
    • WO2006059270A3
    • 2006-08-31
    • PCT/IB2005053935
    • 2005-11-28
    • KONINKL PHILIPS ELECTRONICS NVKAHLMAN JOSEPHUS A H MDE BOER BART M
    • KAHLMAN JOSEPHUS A H MDE BOER BART M
    • G01N27/72
    • G01R33/093B82Y25/00G01R33/1269
    • A magnetic sensor (MS) comprising a magneto-resistive element (GMR) for sensing a magnetic stray field (SF) generated by a magnetizable object (SPB) when magnetized and for generating an electrical object signal (UOB) which depends on the sensed magnetic stray field (SF), the sensor (MS) comprising a magnetic field generator (WR 1 , WR 2 ) for generating a magnetic field (H, H ext ) having a first frequency (? 1 ) for magnetizing the magnetizable object (SPB), a current source (AC 2 ) for at least generating an AC-current (I 2 sin? 2 t) having a second frequency (? 2 t) through the magneto-resistive element (GMR), and electronic means for generating an electrical output signal (U 0 ) derived from the electrical object signal (U OB ), the electronic means comprising stabilization means for stabilizing the amplitude of the electrical output signal (U 0 ), the stabilization means deriving its information which is needed for said stabilization from the amplitude of a signal component, which is present in the object signal (U OB ) during operation, which is linearly dependent on the steepness of the magneto-resistive element (GMR), the steepness being defined as the derivative of the resistance of the magneto-resistive element (GMR) as a function of the magnetic field through the magneto-resistive element in a magnetically sensitive direction of the magneto-resistive element (GMR).
    • 一种磁传感器(MS),包括用于感测由磁化物体(SPB)产生的磁性杂散场(SFB)的磁阻元件(GMR),并且用于产生取决于感测的磁性的电物体信号(UOB) 杂散场(SF),所述传感器(MS)包括用于产生磁场的磁场发生器(WR&lt; 1&gt;,&lt; 2&gt; 2&gt;), 具有用于磁化可磁化物体(SPB)的第一频率(α<1> 1 )的电流源(AC SUB2),用于至少产生AC- 具有通过磁阻元件(GMR)的第二频率(θ2> 2t)的电流(I 2 2 sin 2&lt; 2&gt; t),以及 用于产生从电气对象信号(U OB OB)导出的电输出信号(U SUB)的电子装置,该电子装置包括稳定装置,用于稳定电气信号 输出信号(U0 <0>),稳定装置导出它 根据存在于操作期间的对象信号(U OB OB)中的信号分量的幅度,所述稳定所需的信息是线性地取决于磁阻元件的陡度的信息 (GMR),陡度被定义为磁阻元件(GMR)的电阻的导数,其作为通过磁阻元件在磁阻元件(GMR)的磁敏方向上的磁场的函数, 。