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    • 1. 发明申请
    • METHOD AND APPARATUS FOR IMPROVING IMAGE RESOLUTION
    • 改善图像分辨率的方法和装置
    • WO2008093099A3
    • 2008-10-02
    • PCT/GB2008000338
    • 2008-02-01
    • KING S COLLEGE LONDONHEINTZMANN RAINERWICKER KAI
    • HEINTZMANN RAINERWICKER KAI
    • G02B21/00
    • G02B21/0056
    • Embodiments of the invention allow the operation of confocal microscopes with relatively open pinholes (e.g. 1 Airy unit) whilst still giving a significant XY resolution improvement. In addition axial (Z) discrimination or resolution may also be improved. This is achieved by.splitting the emitted light path in an interf erometric fashion. One of the split beams is then directed to an image transformation system, which may perform an image inversion which inverts at least one coordinate in image space. The transformed beam and the non- trans formed beam are then recombined in an interf erometric fashion (i.e. coherently added), which provides an interference effect resulting in increased resolution of the image. Where the embodiments are being used in a confocal application, the resulting combined beam can then be subject to a spatially discriminating means, such as a pinhole, or the like.
    • 本发明的实施例允许具有相对开放的针孔(例如1个艾里单位)的共焦显微镜的操作,同时仍然给出显着的XY分辨率改进。 此外,还可以提高轴向(Z)辨别或分辨率。 这是通过以交互式测量方式对发射的光路进行分割来实现的。 分割光束中的一个然后被引导到图像变换系统,其可以执行在图像空间中反转至少一个坐标的图像反转。 然后,经过变换的波束和非反射形成的波束以界面测量方式(即相干地添加)重组,这提供了干扰效果,导致图像的分辨率增加。 在实施例用于共焦应用的情况下,所得到的组合光束然后可以经受空间鉴别手段,例如针孔等。